Cited by 203Pituitary Gland Disorders and TreatmentsAdrenal Hormones and DisordersElectrolyte and hormonal disorders

Hypopituitarism

Vance, Mary Lee·1994·New England Journal of Medicine

Abstract

Hypopituitarism may be either partial or complete and may result from either pituitary or hypothalamic disease. Its clinical manifestations vary, depending on the extent and severity of the pituitary hormone deficiency. Thus, a patient may present in extremis with acute adrenal insufficiency or profound hypothyroidism, with symptoms indicating a pituitary mass lesion, or with nonspecific symptoms of fatigue and malaise.Most of the hypothalamic-pituitary-target-organ axes are tightly coordinated systems in which hormonal signals from the hypothalamus stimulate or inhibit secretion of anterior pituitary hormones; these hormones, in turn, act on specific organs. These axes are frequently described as closed-loop or . . .

Integrity signals

Registry

Crossref · 10.1056/nejm199406093302306

Cites

52 of 52 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Cites

Flagged first, then by citations

Cited by

Sorted by citations

Authors
Vance, M. L.
Affiliations
University of Virginia Health System (US)
Corresponding author
Vance, Mary Lee
Venue
New England Journal of Medicine
Published
1994-06-09
Volume
330
Issue
23
Pages
1651-1662
ISSN
  • 0028-4793 (ISSN-L)
  • 1533-4406
OpenAlex
W4249920490
Cited by
203
References
52
Citations by year
2026: 2 · 2025: 3 · 2024: 2 · 2023: 4 · 2021: 6 · 2020: 5 · 2019: 6 · 2018: 6 · 2017: 4 · 2016: 3 · 2015: 4 · 2014: 5 · 2013: 8 · 2012: 8
FWCI
2.30
Type
journal article
Language
en
Open access
closed
Locations
  • New England Journal of Medicine (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Pituitary Gland Disorders and Treatments
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Adrenal Hormones and Disorders
  • Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Electrolyte and hormonal disorders
Keywords
hypopituitarism, pituitary hormone deficiency, hypothalamic disease, pituitary disorders, adrenal insufficiency, hypothyroidism, anterior pituitary hormones
MeSH terms
Humans, Hypopituitarism

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review