Cited by 295Substance Abuse Treatment and OutcomesOpioid Use Disorder TreatmentYouth, Drugs, and Violence

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Management of Cocaine Abuse and Dependence

Mendelson, Jack H., Mello, Nancy K.·1996·New England Journal of Medicine

DOI 10.1056/nejm199604113341507

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Abstract

During the 20th century, there have been recurrent episodes of cocaine abuse in the United States that have achieved epidemic proportions.1 Although the total number of people using the drug has decreased in the past decade, cocaine-related biomedical and psychosocial problems remain a major public health problem in the United States and many other countries. The expanding list of cocaine-related toxic effects, acute and chronic, includes reproductive dysfunction, hepatic necrosis, and pulmonary disease.2 Abuse of and dependence on cocaine may also be associated with disorders of sexual function, sleep, anxiety, and mood, as well as with delirium and psychotic disorders. . . .

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Authors: Mendelson, J. H., & Mello, N. K.
Affiliations: Harvard University (US)
Venue: New England Journal of Medicine
Publisher: Massachusetts Medical Society
Published: 1996-04-11
Volume: 334
Issue: 15
Pages: 965-972
ISSN: 0028-4793 (ISSN-L)
1533-4406
DOI: 10.1056/nejm199604113341507
OpenAlex: W2338649220
Cited by: 291
References: 112
Citations by year: 2024: 4 · 2023: 4 · 2022: 4 · 2021: 3 · 2020: 2 · 2019: 1 · 2018: 3 · 2017: 4 · 2016: 8 · 2015: 7 · 2014: 9 · 2013: 20 · 2012: 14
FWCI: 5.15
Type: journal article
Language: en
Open access: closed
Locations: New England Journal of Medicine (publishedVersion)
PubMed (publishedVersion)
Funders: National Institutes of Health (5r18da006116-05)
National Institute on Drug Abuse (DA 06116, K05DA000064, KO5-DA 00101, KO5 DA 00064, K05DA000101)
Topics: Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Opioid Use Disorder Treatment
Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Youth, Drugs, and Violence
Keywords: cocaine abuse, cocaine dependence, cocaine toxicity, reproductive disorders, liver necrosis, lung disease, sexual dysfunction, sleep disorders, anxiety, mood disorders, delirium, psychosis
MeSH terms: Antidepressive Agents, Carbamazepine, Cocaine, Humans, Narcotic Antagonists, Narcotics, Dopamine Agents, Substance-Related Disorders

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