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Chemokines — Chemotactic Cytokines That Mediate Inflammation

Luster, Andrew D.·1998·New England Journal of Medicine

Abstract

The attraction of leukocytes to tissues is essential for inflammation and the host response to infection. The process is controlled by chemokines, which are chemotactic cytokines. This review introduces the burgeoning family of cytokines, with special emphasis on their role in the pathophysiology of disease and their potential as targets for therapy.Structure and Function of ChemokinesOver 40 chemokines have been identified to date, most of them in the past few years. The relations among chemokines were not initially appreciated, which led to an idiosyncratic nomenclature consisting of many acronyms. When initially identified, these proteins had no known biologic . . .

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Metadata

Authors
Luster, A. D.
Venue
New England Journal of Medicine
Published
1998-02-12
Volume
338
Issue
7
Pages
436-445
ISSN
  • 0028-4793 (ISSN-L)
  • 1533-4406
OpenAlex
W2005659566
Cited by
3,630
References
3
FWCI
112.38
Type
journal article
Language
en
Open access
closed

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Luster, A. D. (1998). Chemokines — Chemotactic Cytokines That Mediate Inflammation. New England Journal of Medicine. https://doi.org/10.1056/nejm199802123380706

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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