The DOI matches its Crossref record; 101 of the 101 references it cites were found in a registry or an index.
Drug Therapy for Alcohol Dependence
Abstract
Alcohol dependence is a chronic disorder that results from a variety of genetic, psychosocial, and environmental factors.1 As defined by the American Psychiatric Association in the Diagnostic and Statistical Manual of Mental Disorders, it is characterized by increased tolerance of the effects of alcohol, impaired control over drinking, and continued drinking despite adverse consequences (Table 1).2 Alcohol dependence affects nearly 10 percent of the population and results in social problems, considerable morbidity and mortality, and high health care costs.3,4 Alcohol dependence is treated by medical, psychological, and social interventions that reduce or eliminate the desire to drink and the . . .
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“Disulfiram blocks the enzyme aldehyde dehydrogenase (ALDH).”
From Disulfiram Efficacy in the Treatment of Alcohol Dependence: A Meta-Analysis (2014) · cites this paper as [8]
Citations
Cites
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Cited by
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Room, R., Babor, T., & Rehm, J. (2005) · The Lancet · doi:10.1016/s0140-6736(05)17870-2 · Cited by 1,625
Gambling and the Health of the Public: Adopting a Public Health Perspective
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“This figure, which coincides with that of previous publications [52,57,64], is clearly a cause for concern as adherence to treatment had shown itself to be a fundamental factor in the remission of alcohol dependence [4,51].”
BackgroundResultAddolorato, G. (2002) · Alcohol and Alcoholism · doi:10.1093/alcalc/37.5.504 · Cited by 479
“However, to date, drugs with proven efficacy are very few (see Garbutt et al., 1999; Swift, 1999; Kranzler, 2000) and the discovery of new medications capable of positively affecting the components of alcohol dependence syndrome, such as craving and loss of control on drinking or protracted…”
BackgroundCamí, J., & Farré, M. (2003) · New England Journal of Medicine · doi:10.1056/nejmra023160 · Cited by 477
Metadata
- Authors
- Swift, R. M.
- Affiliations
- Brown University (US)
- Corresponding author
- Swift, Robert M.
- ORCID
- Swift, Robert M.
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 1999-05-13
- Volume
- 340
- Issue
- 19
- Pages
- 1482-1490
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W1984819772
- Cited by
- 255
- References
- 97
- Citations by year
- 2025: 3 · 2024: 7 · 2022: 7 · 2021: 2 · 2020: 5 · 2019: 4 · 2018: 11 · 2016: 5 · 2015: 9 · 2014: 7 · 2013: 10 · 2012: 5
- FWCI
- 3.88
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- New England Journal of Medicine (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
- Health Sciences › Medicine › Pathology and Forensic Medicine › Alcohol Consumption and Health Effects
- Health Sciences › Medicine › Clinical Neurology › Alcoholism and Thiamine Deficiency
- Keywords
- alcoholism, pharmacotherapy, alcohol tolerance, impaired control, DSM-IV diagnostic criteria, health care costs
- MeSH terms
- Alcohol Deterrents, Ethanol, Alcoholism, Antidepressive Agents, Mental Disorders, Humans, Narcotic Antagonists, Receptors, Neurotransmitter, Dopamine Antagonists
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