The DOI matches its Crossref record; 48 of the 48 references it cites were found in a registry or an index.
The HLA System
Abstract
Deficiencies of HLA MoleculesA clinician's attention is normally drawn to a system only when it malfunctions. The HLA system is no exception in this regard, but in contrast to other systems, it also arouses interest when it functions well — too well, in fact. The most dramatic malfunction of the HLA system occurs when its genes falter in their expression, resulting in HLA class I or class II deficiencies (the bare lymphocyte syndrome, in which “bare” refers to the low level of HLA molecules on the cell surface). Severe cases of HLA deficiencies are, in fact, not caused by . . .
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
A novel MHC class I-like gene is mutated in patients with hereditary haemochromatosis
Feder, J. N., Gnirke, A., Thomas, W., Tsuchihashi, Z., Ruddy, D. A., Basava, A., Dormishian, F., Domingo, R., Ellis, M. C., Fullan, A., et al. (1996) · Nature Genetics · doi:10.1038/ng0896-399 · Cited by 3,664
Phenotypic Analysis of Antigen-Specific T Lymphocytes
Altman, J. D., Moss, P. A. H., Goulder, P. J. R., Barouch, D. H., McHeyzer-Williams, M. G., Bell, J. I., McMichael, A. J., & Davis, M. M. (1996) · Science · doi:10.1126/science.274.5284.94 · Cited by 3,544
Narcolepsy in orexin Knockout Mice
Chemelli, R. M., Willie, J. T., Sinton, C. M., Elmquist, J. K., Scammell, T., Lee, C., Richardson, J. A., Williams, S. C., Xiong, Y., Kisanuki, Y., et al. (1999) · Cell · doi:10.1016/s0092-8674(00)81973-x · Cited by 3,095
Lin, L., Faraco, J., Li, R., Kadotani, H., Rogers, W., Lin, X., Qiu, X., de Jong, P. J., Nishino, S., & Mignot, E. (1999) · Cell · doi:10.1016/s0092-8674(00)81965-0 · Cited by 2,613
Andrews, N. C. (1999) · New England Journal of Medicine · doi:10.1056/nejm199912233412607 · Cited by 2,130
Common West African HLA antigens are associated with protection from severe malaria
Hill, A. V. S., Allsopp, C. E. M., Kwiatkowski, D., Anstey, N. M., Twumasi, P., Rowe, P. A., Bennett, S., Brewster, D., McMichael, A. J., & Greenwood, B. M. (1991) · Nature · doi:10.1038/352595a0 · Cited by 1,552
HLA and HIV-1: Heterozygote Advantage and B*35-Cw*04 Disadvantage
Carrington, M., Nelson, G. W., Martin, M. P., Kissner, T., Vlahov, D., Goedert, J. J., Kaslow, R., Buchbinder, S., Hoots, K., & O'Brien, S. J. (1999) · Science · doi:10.1126/science.283.5408.1748 · Cited by 1,224
IMMUNODOMINANCE IN MAJOR HISTOCOMPATIBILITY COMPLEX CLASS I–RESTRICTED T LYMPHOCYTE RESPONSES
Yewdell, J. W., & Bennink, J. R. (1999) · Annual Review of Immunology · doi:10.1146/annurev.immunol.17.1.51 · Cited by 944
Tiwari, J. L., & Terasaki, P. I. (1985) · Springer eBooks · doi:10.1007/978-1-4613-8545-5 · Cited by 876
Feder, J. N., Penny, D. M., Irrinki, A., Lee, V. K., Lebrón, J. A., Watson, N., Tsuchihashi, Z., Sigal, E., Bjorkman, P. J., & Schatzman, R. C. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.4.1472 · Cited by 827
Cited by
Genetic Mapping in Human Disease
Altshuler, D., Daly, M. J., & Lander, E. S. (2008) · Science · doi:10.1126/science.1156409 · Cited by 1,452
Davidson, A., & Diamond, B. (2001) · New England Journal of Medicine · doi:10.1056/nejm200108023450506 · Cited by 1,042
Betterle, C., Dal Pra, C., Mantero, F., & Zanchetta, R. (2002) · Endocrine Reviews · doi:10.1210/edrv.23.3.0466 · Cited by 758
Genetics of multiple sclerosis
Dyment, D. A., Ebers, G. C., & Dessa Sadovnick, A. (2004) · The Lancet Neurology · doi:10.1016/s1474-4422(03)00663-x · Cited by 563
Acute Anterior Uveitis and HLA-B27
Chang, J. H., McCluskey, P. J., & Wakefield, D. (2005) · Survey of Ophthalmology · doi:10.1016/j.survophthal.2005.04.003 · Cited by 365
Metadata
- Authors
- Klein, J., & Sato, A.
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 2000-09-14
- Volume
- 343
- Issue
- 11
- Pages
- 782-786
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W64278426
- Cited by
- 446
- References
- 48
- FWCI
- 5.85
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: The HLA System. https://app.cochat.ai/papers/10.1056/nejm200009143431106
- The paper
- Klein, J., & Sato, A. (2000). The HLA System. New England Journal of Medicine. https://doi.org/10.1056/nejm200009143431106
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.