The DOI matches its Crossref record; 177 of the 177 references it cites were found in a registry or an index.
Cardiovascular Complications of Cocaine Use
Abstract
The deaths of several celebrities in recent years in association with the nontherapeutic use of cocaine have focused widespread attention on the problem of cocaine abuse. In 1999, an estimated 25 million Americans admitted that they had used cocaine at least once; 3.7 million had used it within the previous year; and 1.5 million were current users. During the same year, cocaine was mentioned in 30 percent of all drug-related visits to emergency departments.1 Cocaine is the most commonly used illicit drug among subjects seeking care in hospital emergency departments or drug-treatment centers. In addition, it is the most frequent . . .
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“Likewise, stimulants such as caffeine and nicotine, or the use of illicit drugs (cocaine, heroin, amphetamines, LSD, synthetic drugs, cannabis, etc.) can lead to sympathetic hyperactivation and sinus tachycardia, even in young subjects without heart disease.41,42”
From Management of patients with palpitations: a position paper from the European Heart Rhythm Association (2011) · cites this paper as [42]
In the citing paper
“Indeed, it is not always possible to establish a definite cause of palpitations; often, only a likely cause can be given, and, in some cases, several possible causes have to be taken into consideration.8,42”
From Management of patients with palpitations: a position paper from the European Heart Rhythm Association (2011) · cites this paper as [42]
Citations
Cites
Gawin, F. H., & Ellinwood, E. H. (1988) · New England Journal of Medicine · doi:10.1056/nejm198805053181806 · Cited by 965
Cocaine-Induced Coronary-Artery Vasoconstriction
Lange, R. A., Cigarroa, R. G., Yancy, C. W., Willard, J. E., Popma, J. J., Sills, M. N., McBride, W., Kim, A. S., & Hillis, L. D. (1989) · New England Journal of Medicine · doi:10.1056/nejm198912073212301 · Cited by 619
New concepts in cocaine addiction: The dopamine depletion hypothesis
Dackis, C. A., & Gold, M. S. (1985) · Neuroscience & Biobehavioral Reviews · doi:10.1016/0149-7634(85)90022-3 · Cited by 607
Acute Cardiac Events Temporally Related to Cocaine Abuse
Isner, J. M., Estes, N. A. M., Thompson, P. D., Costanzo-Nordin, M. R., Subramanian, R., Miller, G., Katsas, G. G., Sweeney, K. G., & Sturner, W. Q. (1986) · New England Journal of Medicine · doi:10.1056/nejm198612043152302 · Cited by 598
Temporal Patterns of Cocaine Use in Pregnancy
Chasnoff, I. J. (1989) · JAMA · doi:10.1001/jama.1989.03420120079030 · Cited by 452
Triggering of Myocardial Infarction by Cocaine
Mittleman, M. A., Mintzer, D. M., Maclure, M., Tofler, G. H., Sherwood, J. B., & Muller, J. E. (1999) · Circulation · doi:10.1161/01.cir.99.21.2737 · Cited by 440
Potentiation of Cocaine-Induced Coronary Vasoconstriction by Beta-Adrenergic Blockade
Lange, R. A., Cigarroa, R. G., Flores, E. D., McBride, W., Kim, A. S., Wells, P. J., Bedotto, J. B., Danziger, R. S., & Hillis, L. D. (1990) · Annals of Internal Medicine · doi:10.7326/0003-4819-112-12-897 · Cited by 414
Synthesis of Prostacyclin from Platelet-derived Endoperoxides by Cultured Human Endothelial Cells
Marcus, A. J., Weksler, B. B., JAFFE, E. A., & Broekman, M. J. (1980) · Journal of Clinical Investigation · doi:10.1172/jci109967 · Cited by 380
Perinatal cerebral infarction and maternal cocaine use
Chasnoff, I. J., Bussey, M. E., Savich, R. D., & Stack, C. M. (1986) · The Journal of Pediatrics · doi:10.1016/s0022-3476(86)80896-4 · Cited by 372
Cerebrovascular Complications of the Use of the Crack Form of Alkaloidal Cocaine
Levine, S. R., Brust, J. C. M., Futrell, N., Ho, K. L., Blake, D., Millikan, C. H., Brass, L. M., Fayad, P. B., Schultz, L. R., Selwa, J. F., et al. (1990) · New England Journal of Medicine · doi:10.1056/nejm199009133231102 · Cited by 366
Research works printed but not linked: 10
- Jeffcoat AR, 1989, Drug Metab Dispos, 17, 153
- Coleman DL, 1982, West J Med, 136, 444
- Hollander JE, 1997, Vet Hum Toxicol, 39, 276
- Stenberg RG, 1989, Arch Pathol Lab Med, 113, 521
- Hollander JE, 1992, N Engl J Med, 327, 361
- 2000, Circulation, 102, I, 10.1161/01.CIR.102.suppl_2.1-i · DOI
- Escobedo LG, 1991, Arch Pathol Lab Med, 115, 900
- 10.1001/archinte.155.11.1186 · DOI
- Xiao Y, 2000, J Pharmacol Exp Ther, 292, 8
- Wit AL, Rosen MR. After depolarizations and triggered activity. In: Fozzard HA, Haber E, Jennings RB, Katz AM, Morgan HE, eds. The heart and cardiovascular system: scientific foundations. Vol. 2. New York: Raven Press, 1986:1449-90.
Cited by
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Items 801–807 of 807
The Poisoned Patient, Part 1: Interpreting Vital Signs Through a Toxicologic Lens
Trebach, J. D., & McCabe, D. (2026) · The American Journal of Emergency Medicine · doi:10.1016/j.ajem.2026.09.038
Heart Changes Due to Combined Effects with Alcohol: Caffeine and Beyond
Ma, S., & Zhang, Y. (2026) · Springer eBooks · doi:10.1007/978-3-031-35658-2_111-1
Kousteni, M., Kalk, N. J., & Copeland, C. S. (2026) · BJPsych Open · doi:10.1192/bjo.2026.12121
Emergency Management of Cocaine & Amphetamine Overdose is Important
Draghmeh, K., Gold, M. S., Fuehrlein, B., & Hicks, A. (2026) · Current Addiction Reports · doi:10.1007/s40429-026-00799-z
Demystifying Imaging Patterns of Substance Abuse-Related Lung Injury (SARLI)
Sharma, S., Davoudi, D., Patsios, D., & McInnis, M. C. (2026) · Canadian Association of Radiologists Journal · doi:10.1177/08465371261491714
Recurrent myocardial infarction in a young cocaine abuser
Stiha, R., Raissouni, Z., Ess-bai, B., Oukerraj, L., Zarzur, J., & Cherti, M. (2015) · DOAJ (DOAJ: Directory of Open Access Journals) · doi:10.11604/pamj.2015.21.194.7265
Brust, J. C. M. (2007) · Elsevier eBooks · doi:10.1016/b978-2-84299-712-0.50005-x
Metadata
- Authors
- Lange, R. A., & Hillis, L. D.
- Affiliations
- The University of Texas Southwestern Medical Center (US)
- ORCID
- Lange, Richard A.
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 2001-08-02
- Volume
- 345
- Issue
- 5
- Pages
- 351-358
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W2338565293
- Cited by
- 810
- References
- 176
- Citations by year
- 2026: 15 · 2025: 13 · 2024: 11 · 2023: 23 · 2022: 29 · 2021: 17 · 2020: 22 · 2019: 27 · 2018: 23 · 2017: 18 · 2016: 24 · 2015: 46 · 2014: 41 · 2013: 34 · 2012: 38
- FWCI
- 26.97
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- New England Journal of Medicine (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Youth, Drugs, and Violence
- Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Toxicology › Forensic Toxicology and Drug Analysis
- Keywords
- cocaine use, cardiovascular complications, cocaine abuse, cocaine-related deaths, emergency department visits, illicit drug use, drug-related hospitalizations
- MeSH terms
- Ethanol, Aortic Dissection, Aortic Aneurysm, Arrhythmias, Cardiac, Cocaine, Drug Synergism, Endocarditis, Heart Diseases, Humans, Myocardial Infarction, Smoking, Myocardial Ischemia
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