Ketoacidosis during a Low-Carbohydrate Diet
Open accessAbstract
To the Editor: It is believed that low-carbohydrate diets work best in reducing weight when producing ketosis.1 We report on a 51-year-old white woman who does not have diabetes but had ketoacidosis while consuming a “no-carbohydrate” diet. There was no family history of diabetes, and she was not currently taking any medications. While adhering to a regimen of carbohydrate restriction, she reached a stable weight of 59.1 kg, a decrease from 72.7 kg. After several months of stable weight, she was admitted to the hospital four times with vomiting but without abdominal pain. On each occasion, she reported no alcohol . . .
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Metabolic ketoacidosis with ketogenic diets is a hazard, particularly with sodium−glucose cotransporter 2 (SGLT2) inhibitors.
“Metabolic ketoacidosis with ketogenic diets is a hazard, particularly with sodium−glucose cotransporter 2 (SGLT2) inhibitors [82–87].”
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- Authors
- Shah, P., & Isley, W. L.
- Affiliations
- Mayo Clinic (US)
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 2006-01-05
- Volume
- 354
- Issue
- 1
- Pages
- 97-98
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W2095471147
- Cited by
- 95
- References
- 5
- Citations by year
- 2026: 1 · 2025: 6 · 2024: 7 · 2023: 4 · 2022: 3 · 2021: 14 · 2020: 11 · 2019: 7 · 2018: 2 · 2017: 4 · 2016: 6 · 2015: 4 · 2014: 1 · 2013: 1 · 2012: 1
- FWCI
- 3.31
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- New England Journal of Medicine (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Physiology › Diet and metabolism studies
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Research
- Health Sciences › Medicine › Physiology › Dietary Effects on Health
- Keywords
- ketoacidosis, low-carbohydrate diet, carbohydrate restriction, weight loss, vomiting, ketosis
- MeSH terms
- Blood Glucose, Dietary Fats, Fatty Acids, Female, Humans, Ketosis, Middle Aged, Obesity, Diet, Carbohydrate-Restricted
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