Glutamine and Antioxidants in Critically Ill Patients
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The only negative trial in terms of absence of effect was attributed to the delivery of a dose of GLN lower than recommended.
“The only negative trial in terms of absence of effect was attributed to the delivery of a dose of GLN lower than recommended (231).”
From ESPEN guideline on clinical nutrition in the intensive care unit. (2019) · cites this paper as [231]
Since the 1990s, many studies have shown benefits in terms of infectious complication reduction, lower mortality and reduction of hospital costs recently confirmed in an analysis including RCTs performed after 2000, using GLN as part of nutrition support.
“Since the 1990s, many studies have shown benefits in terms of infectious complication reduction, lower mortality and reduction of hospital costs recently confirmed in an analysis including RCTs performed after 2000, using GLN as part of nutrition support [84].”
From ESPEN practical and partially revised guideline: Clinical nutrition in the intensive care unit (2023) · cites this paper as [84]
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- Authors
- Heyland, D., Wischmeyer, P. E., & Day, A. G.
- Corresponding author
- Daren Heyland
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 2013-08
- Volume
- 369
- Issue
- 5
- Pages
- 482-485
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W3187093756
- Cited by
- 56
- References
- 14
- Citations by year
- 2025: 3 · 2024: 1 · 2023: 2 · 2021: 3 · 2020: 3 · 2019: 4 · 2018: 6 · 2017: 5 · 2016: 8 · 2015: 14 · 2014: 6 · 2013: 1
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- New England Journal of Medicine (publishedVersion)
- PubMed (publishedVersion)
- Pure Amsterdam UMC (publishedVersion)
- Topics
- Health Sciences › Nursing › Nutrition and Dietetics › Clinical Nutrition and Gastroenterology
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Health Sciences › Medicine › Critical Care and Intensive Care Medicine › Intensive Care Unit Cognitive Disorders
- Keywords
- glutamine, antioxidants, critically ill patients, intensive care, nutritional support, oxidative stress
- MeSH terms
- Antioxidants, Female, Glutamine, Humans, Male, Multiple Organ Failure, Respiration, Artificial
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