The Exercise Pill — Too Good to Be True?

AMPK and PPARδ Agonists Are Exercise Mimetics

Narkar, V. A., Downes, M., Yu, R. T., Embler, E., Wang, Y.-X., Banayo, E., Mihaylova, M. M., Nelson, M. C., Zou, Y., Juguilon, H., et al. (2008) · Cell · doi:10.1016/j.cell.2008.06.051 · Cited by 1,222 · see citing works

Chronic activation of 5′-AMP-activated protein kinase increases GLUT-4, hexokinase, and glycogen in muscle

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AMP-activated protein kinase regulates gene expression by direct phosphorylation of nuclear proteins

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Genetic model for the chronic activation of skeletal muscle AMP-activated protein kinase leads to glycogen accumulation

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Targeting the AMP-Activated Protein Kinase for the Treatment of Type 2 Diabetes

Musi, N., & Goodyear, L. J. (2002) · Current Drug Targets - Immune Endocrine & Metabolic Disorders · doi:10.2174/1568005310202020119 · Cited by 68 · see citing works

Targeting the AMP-Activated Protein Kinase for the Treatment of Type 2 Diabetes

Musi, N., & Goodyear, L. J. (2002) · Current Drug Targets - Immune Endocrine & Metabolic Disorders · doi:10.2174/1568008023340730 · Cited by 15 · see citing works

A within-trial cost-effectiveness analysis of primary care referral to a commercial provider for weight loss treatment, relative to standard care—an international randomised controlled trial

Fuller, N. R., Colagiuri, S., SCHOFIELD, D. J., Olson, A. D., Shrestha, R. N., Holzapfel, C., Wolfenstetter, S. B., Holle, R., Ahern, A. L., Hauner, H., et al. (2012) · International Journal of Obesity · doi:10.1038/ijo.2012.139 · Cited by 2,125 · see citing works

Metabolic Syndrome and Insulin Resistance: Underlying Causes and Modification by Exercise Training

Roberts, C. K., Hevener, A. L., & Barnard, R. J. (2012) · Comprehensive physiology · doi:10.1002/cphy.c110062 · Cited by 919 · see citing works

Exercise is the real polypill.

Fiuza-Luces, C., Garatachea, N., Berger, N. A., & Lucia, A. (2013) · Physiology · doi:10.1152/physiol.00019.2013 · Cited by 791 · see citing works

Cellular bioenergetics as a target for obesity therapy

Tseng, Y.-H., Cypess, A. M., & Kahn, C. R. (2010) · Nature Reviews Drug Discovery · doi:10.1038/nrd3138 · Cited by 591 · see citing works

Targeting vascular (endothelial) dysfunction

Daiber, A., Steven, S., Weber, A., Shuvaev, V. V., Muzykantov, V. R., Laher, I., Li, H., Lamas, S., & Münzel, T. (2017) · British Journal of Pharmacology · doi:10.1111/bph.13517 · Cited by 501 · see citing works

Exercise acts as a drug; the pharmacological benefits of exercise

Vina, J., Sanchis‐Gomar, F., Martinez‐Bello, V, & Gomez‐Cabrera, M. (2012) · British Journal of Pharmacology · doi:10.1111/j.1476-5381.2012.01970.x · Cited by 443 · see citing works

Of mice and men: the benefits of caloric restriction, exercise, and mimetics

Mercken, E. M., Carboneau, B. A., Krzysik-Walker, S. M., & de Cabo, R. (2012) · Ageing Research Reviews · doi:10.1016/j.arr.2011.11.005 · Cited by 318 · see citing works

Optimal management of sarcopenia

Sumukadas, D. (2010) · Clinical Interventions in Aging · doi:10.2147/cia.s11473 · Cited by 303 · see citing works

AMP-activated protein kinase: an emerging drug target to regulate imbalances in lipid and carbohydrate metabolism to treat cardio-metabolic diseases

Srivastava, R. A. K., Pinkosky, S. L., Filippov, S. I., Hanselman, J. C., Cramer, C. T., & Newton, R. S. (2012) · Journal of Lipid Research · doi:10.1194/jlr.r025882 · Cited by 297 · see citing works

AMP-activated protein kinase, stress responses and cardiovascular diseases

Wang, S., Song, P., & Zou, M. (2012) · Clinical Science · doi:10.1042/cs20110625 · Cited by 243 · see citing works

Peroxisome Proliferator-activated Receptor γ Coactivator 1α or 1β Overexpression Inhibits Muscle Protein Degradation, Induction of Ubiquitin Ligases, and Disuse Atrophy

Brault, J. J., Jespersen, J. G., & Goldberg, A. L. (2010) · Journal of Biological Chemistry · doi:10.1074/jbc.m110.113092 · Cited by 217 · see citing works

Exercise training and pulmonary rehabilitation: new insights and remaining challenges

Troosters, T., Gosselink, R., Janssens, W., & Decramer, M. (2010) · European Respiratory Review · doi:10.1183/09059180.00007809 · Cited by 138 · see citing works

Adenosine Monophosphate-Activated Protein Kinase (AMPK) as a New Target for Antidiabetic Drugs: A Review on Metabolic, Pharmacological and Chemical Considerations

Gruzman, A., Babai-Shani, G., & Sasson, S. (2009) · The Review of Diabetic Studies · doi:10.1900/rds.2009.6.13 · Cited by 128 · see citing works

Peroxisome Proliferator-activated Receptor γ Coactivator 1α (PGC-1α) Promotes Skeletal Muscle Lipid Refueling in Vivo by Activating de Novo Lipogenesis and the Pentose Phosphate Pathway*

Summermatter, S., Baum, O., Santos, G., Hoppeler, H. H., & Handschin, C. (2010) · Journal of Biological Chemistry · doi:10.1074/jbc.m110.145995 · Cited by 114 · see citing works

Emerging concepts in the therapy of mitochondrial disease

Viscomi, C. F., Bottani, E., & Zeviani, M. (2015) · Biochimica et Biophysica Acta (BBA) - Bioenergetics · doi:10.1016/j.bbabio.2015.03.001 · Cited by 107 · see citing works

Lack of adequate appreciation of physical exercise's complexities can pre‐empt appropriate design and interpretation in scientific discovery

Booth, F. W., & Laye, M. J. (2009) · The Journal of Physiology · doi:10.1113/jphysiol.2009.179507 · Cited by 99 · see citing works

Irisin: A new potential hormonal target for the treatment of obesity and type 2 diabetes

Sanchis‐Gomar, F., Lippi, G., Mayero, S., Pérez-Quilis, C., & García‐Giménez, J. L. (2012) · Journal of Diabetes · doi:10.1111/j.1753-0407.2012.00194.x · Cited by 96 · see citing works

AMPK Activation via Modulation of De Novo Purine Biosynthesis with an Inhibitor of ATIC Homodimerization

Asby, D. J., Cuda, F., Beyaert, M., Houghton, F. D., Cagampang, F. R. A., & Tavassoli, A. (2015) · Chemistry & Biology · doi:10.1016/j.chembiol.2015.06.008 · Cited by 89 · see citing works

Therapeutic Approaches to Treat Mitochondrial Diseases: “One-Size-Fits-All” and “Precision Medicine” Strategies

Bottani, E., Lamperti, C., Prigione, A., Tiranti, V., Persico, N., & Brunetti, D. (2020) · Pharmaceutics · doi:10.3390/pharmaceutics12111083 · Cited by 85 · see citing works

Resistance to Aerobic Exercise Training Causes Metabolic Dysfunction and Reveals Novel Exercise-Regulated Signaling Networks

Lessard, S. J., Rivas, D. A., Alves-Wagner, A. B., Hirshman, M. F., Gallagher, I. J., Constantin‐Teodosiu, D., Atkins, R. P., Greenhaff, P. L., Qi, N., Gustafsson, T. P., et al. (2013) · Diabetes · doi:10.2337/db13-0062 · Cited by 85 · see citing works

Mimicking exercise: what matters most and where to next?

Hawley, J. A., Joyner, M. J., & GREEN, D. J. (2019) · The Journal of Physiology · doi:10.1113/jp278761 · Cited by 81 · see citing works

Current and Future Drug Targets in Weight Management

Witkamp, R. F. (2010) · Pharmaceutical Research · doi:10.1007/s11095-010-0341-1 · Cited by 78 · see citing works

Is Quadriceps Endurance Reduced in COPD?

Evans, R. A., Kaplovitch, E., Beauchamp, M. K., Dolmage, T. E., Goldstein, R. S., Gillies, C. L., Brooks, D., & Mathur, S. (2014) · CHEST Journal · doi:10.1378/chest.14-1079 · Cited by 75 · see citing works

State of Knowledge on Molecular Adaptations to Exercise in Humans: Historical Perspectives and Future Directions

Lavin, K. M., Coen, P. M., Baptista, L. C. P., Bell, M. B., Drummer, D. J., Harper, S. A., Lixandrão, M. E., McAdam, J. S., O’Bryan, S. M., Ramos, S. V., et al. (2022) · Comprehensive physiology · doi:10.1002/cphy.c200033 · Cited by 74 · see citing works

Emerging drugs: mechanism of action, mass spectrometry and doping control analysis

Thevis, M., Thomas, A., Kohler, M., Beuck, S., & Schänzer, W. (2009) · Journal of Mass Spectrometry · doi:10.1002/jms.1584 · Cited by 61 · see citing works

Sedentarismo, exercício físico e doenças crônicas

Gualano, B., & Tinucci, T. (2011) · Revista Brasileira de Educação Física e Esporte · doi:10.1590/s1807-55092011000500005 · Cited by 59 · see citing works

Chronic β2‐adrenoceptor agonist treatment alters muscle proteome and functional adaptations induced by high intensity training in young men

Hostrup, M., Onslev, J., Jacobson, G. A., Wilson, R., & Bangsbo, J. (2017) · The Journal of Physiology · doi:10.1113/jp274970 · Cited by 54 · see citing works

Endurance Exercise Mimetics in Skeletal Muscle

Matsakas, A., & Narkar, V. A. (2010) · Current Sports Medicine Reports · doi:10.1249/jsr.0b013e3181e93938 · Cited by 52 · see citing works

A Study of the Effects of Exercise on the Urinary Metabolome Using Normalisation to Individual Metabolic Output

Daskalaki, E., Blackburn, G. J., Kalna, G., Zhang, T., Anthony, N. G., & Watson, D. G. (2015) · Metabolites · doi:10.3390/metabo5010119 · Cited by 52 · see citing works

Muscle-Specific Overexpression of PGC-1α Does Not Augment Metabolic Improvements in Response to Exercise and Caloric Restriction

Wong, K. E., Mikus, C. R., Slentz, D. H., Seiler, S. E., DeBalsi, K. L., Ilkayeva, O., Crain, K. I., Kinter, M. T., Kien, C. L., Stevens, R. D., et al. (2014) · Diabetes · doi:10.2337/db14-0827 · Cited by 47 · see citing works

Novel pharmacological approaches to combat obesity and insulin resistance: targeting skeletal muscle with ‘exercise mimetics’

Carey, A. L., & Kingwell, B. A. (2009) · Diabetologia · doi:10.1007/s00125-009-1420-x · Cited by 47 · see citing works

Utilizing small nutrient compounds as enhancers of exercise-induced mitochondrial biogenesis

Craig, D. M., Ashcroft, S. P., Belew, M. Y., Stocks, B., Currell, K., Baar, K., & Philp, A. (2015) · Frontiers in Physiology · doi:10.3389/fphys.2015.00296 · Cited by 45 · see citing works

Quantification of urinary AICAR concentrations as a matter of doping controls

Thomas, A., Beuck, S., Eickhoff, J. C., Guddat, S., Krug, O., Kamber, M., Schänzer, W., & Thevis, M. (2010) · Analytical and Bioanalytical Chemistry · doi:10.1007/s00216-010-3560-8 · Cited by 43 · see citing works

Arctigenin Efficiently Enhanced Sedentary Mice Treadmill Endurance

Tang, X., Zhuang, J., Chen, J., Yu, L., Hu, L., Jiang, H., & Shen, X. (2011) · PLoS ONE · doi:10.1371/journal.pone.0024224 · Cited by 41 · see citing works

Current trends and future prospects of lipstatin: a lipase inhibitor and pro-drug for obesity

Kumar, P., & Dubey, K. K. (2015) · RSC Advances · doi:10.1039/c5ra14892h · Cited by 38 · see citing works

A Randomized Controlled Trial of Angiotensin-Converting Enzyme Inhibition for Skeletal Muscle Dysfunction in COPD

Shrikrishna, D., Tanner, R., Lee, J. Y., Natanek, S. A., Lewis, A., Murphy, P. B., Hart, N., Moxham, J., Montgomery, H., Kemp, P. R., et al. (2014) · CHEST Journal · doi:10.1378/chest.13-2483 · Cited by 37 · see citing works

Concurrent Treatment with Ursolic Acid and Low-Intensity Treadmill Exercise Improves Muscle Atrophy and Related Outcomes in Rats

Kim, J. C., Kang, Y. S., Noh, E. B., Seo, B. W., Seo, D. Y., Park, G. D., & Kim, S. H. (2018) · The Korean Journal of Physiology & Pharmacology · doi:10.4196/kjpp.2018.22.4.427 · Cited by 36 · see citing works

Pharmacological Properties of Physical Exercise in The Elderly

Viña, J., Borrás, C., Sanchis‐Gomar, F., Martinez-Bello, V. E., González, G. O., Gambini, J., Inglés, M., & Gómez‐Cabrera, M. C. (2014) · Current Pharmaceutical Design · doi:10.2174/13816128113196660704 · Cited by 36 · see citing works

The AMPK activator R419 improves exercise capacity and skeletal muscle insulin sensitivity in obese mice

Marcinko, K., Bujak, A. L., Lally, J., Ford, R. J., Wong, T. H., Smith, B. K., Kemp, B. E., Jenkins, Y., Li, W., Kinsella, T. M., et al. (2015) · Molecular Metabolism · doi:10.1016/j.molmet.2015.06.002 · Cited by 35 · see citing works

Mitochondrial disorders and drugs: what every physician should know

Orsucci, D., Ienco, E. C., Siciliano, G., & Mancuso, M. (2019) · Drugs in Context · doi:10.7573/dic.212588 · Cited by 35 · see citing works

Anti-inflammatory Property of AMP-activated Protein Kinase

Noor, H. B., Mou, N. A., Salem, L., Shimul, M. F. A., Biswas, S., Akther, R., Khan, S., Raihan, S., Mohib, M. M., & Sagor, M. A. T. (2019) · Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry · doi:10.2174/1871523018666190830100022 · Cited by 32 · see citing works

Intravenous AICAR During Hyperinsulinemia Induces Systemic Hemodynamic Changes but Has No Local Metabolic Effect

Bosselaar, M., Smits, P., van Loon, L. J. C., & Tack, C. J. (2010) · The Journal of Clinical Pharmacology · doi:10.1177/0091270010382912 · Cited by 30 · see citing works

Neuronal nitric oxide synthase is indispensable for the cardiac adaptive effects of exercise

Roof, S. R., Tang, L., Ostler, J. E., Periasamy, M., Györke, S., Billman, G. E., & Ziolo, M. T. (2013) · Basic Research in Cardiology · doi:10.1007/s00395-013-0332-6 · Cited by 30 · see citing works

One-day workshop-based training improves physical activity prescription knowledge in Latin American physicians: a pre-test post-test study

Calle, M. C. A., Lobelo, F., Jiménez-Mora, M. A., Páez, D. C., Cortés, S., de Lima, A., & Duperly, J. (2016) · BMC Public Health · doi:10.1186/s12889-016-3883-2 · Cited by 30 · see citing works

From Gene Engineering to Gene Modulation and Manipulation: Can We Prevent or Detect Gene Doping in Sports?

Fischetto, G., & Bermon, S. (2013) · Sports Medicine · doi:10.1007/s40279-013-0075-4 · Cited by 29 · see citing works

Aerobic training as an adjunctive therapy to enzyme replacement in Pompe disease

Nilsson, M. I., Samjoo, I. A., Hettinga, B. P., Koeberl, D. D., Zhang, H., Hawke, T. J., Nissar, A. A., Ali, T., Brandt, L., Ansari, M. U., et al. (2012) · Molecular Genetics and Metabolism · doi:10.1016/j.ymgme.2012.09.010 · Cited by 28 · see citing works

Targeting RalGAPα1 in skeletal muscle to simultaneously improve postprandial glucose and lipid control

Chen, Q., Rong, P., Zhu, S., Yang, X., Ouyang, Q., Wang, H. Y., & Chen, S. (2019) · Science Advances · doi:10.1126/sciadv.aav4116 · Cited by 27 · see citing works

Combined aerobic exercise and enzyme replacement therapy rejuvenates the mitochondrial–lysosomal axis and alleviates autophagic blockage in Pompe disease

Nilsson, M. I., MacNeil, L., Kitaoka, Y., Suri, R. S., Young, S. P., Kaczor, J. J., Nates, N., Ansari, M. U., Wong, T. W. Y., Ahktar, M. A., et al. (2015) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2015.05.019 · Cited by 27 · see citing works

Paradoja: "activo físicamente pero sedentario, sedentario pero activo físicamente". Nuevos antecedentes, implicaciones en la salud y recomendaciones

Cristi‐Montero, C., & Rodríguez, R. F. (2014) · Revista médica de Chile · doi:10.4067/s0034-98872014000100011 · Cited by 27 · see citing works

AMP-activated protein kinase modulators: a patent review (2006 – 2010)

Yun, H., & Ha, J. (2011) · Expert Opinion on Therapeutic Patents · doi:10.1517/13543776.2011.577069 · Cited by 26 · see citing works

El trasfondo económico de las intervenciones sanitarias en la prevención de la obesidad

Rodrı́guez, A., & López‐Valcárcel, B. G. (2009) · Revista Española de Salud Pública · doi:10.1590/s1135-57272009000100003 · Cited by 25 · see citing works

AICAR Prevents Acute Olanzapine-Induced Disturbances in Glucose Homeostasis

Bush, N. D., Townsend, L. K., & Wright, D. C. (2018) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.118.248393 · Cited by 25 · see citing works

Quantification of AICAR-ribotide concentrations in red blood cells by means of LC-MS/MS

Thomas, A., Vogel, M., Piper, T., Krug, O., Beuck, S., Schänzer, W., & Thevis, M. (2013) · Analytical and Bioanalytical Chemistry · doi:10.1007/s00216-013-7162-0 · Cited by 23 · see citing works

Voluntary Running Attenuates Metabolic Dysfunction in Ovariectomized Low-Fit Rats

Park, Y.-M., Padilla, J., Kanaley, J. A., Zidon, T. M., Welly, R. J., Britton, S. L., Koch, L. G., Thyfault, J. P., Booth, F. W., & Vieira‐Potter, V. J. (2016) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0000000000001101 · Cited by 22 · see citing works

Exercise-like effects by Estrogen-related receptor-gamma in muscle do not prevent insulin resistance in db/db mice

Badin, P.-M., Vila, I. K., Sopariwala, D. H., Yadav, V., Lorca, S., Louche, K., Kim, E. R., Tong, Q., Song, M. S., Moro, C., et al. (2016) · Scientific Reports · doi:10.1038/srep26442 · Cited by 21 · see citing works

Catalase activity prevents exercise-induced up-regulation of vasoprotective proteins in venous tissue

Dao, V. T.-V., Floeren, M., Kumpf, S., Both, C., Peter, B., Balz, V., Suvorava, T., & Kojda, G. (2010) · Journal of Cellular and Molecular Medicine · doi:10.1111/j.1582-4934.2010.01227.x · Cited by 21 · see citing works

Recent insights on chronic heart failure, cachexia and nutrition

Miján-de-la-Torre, A. (2009) · Current Opinion in Clinical Nutrition & Metabolic Care · doi:10.1097/mco.0b013e32832a2171 · Cited by 21 · see citing works

Physical inactivity is a disease synonymous for a non-permissive brain disorder

Pruimboom, L. (2011) · Medical Hypotheses · doi:10.1016/j.mehy.2011.07.022 · Cited by 19 · see citing works

Physical activity, hydration and health.

Marcos, A., Manonelles, P., Palacios, N., Wärnberǵ, J., Casajús, J. A., Pérez, M., Aznar, S., Benito, P. J., Martínez‐Gómez, D., Ortega, F. B., et al. (2014) · PubMed · doi:10.3305/nh.2014.29.6.7624 · Cited by 19 · see citing works

Acute, next‐generation AMPK activation initiates a disease‐resistant gene expression program in dystrophic skeletal muscle

Ng, S. Y., Mikhail, A. I., Mattina, S. R., Manta, A., Diffey, I. J., & Ljubicic, V. (2023) · The FASEB Journal · doi:10.1096/fj.202201846rr · Cited by 18 · see citing works

AMP-independent activator of AMPK for treatment of mitochondrial disorders

Moore, T., Yanes, R. E., Calton, M. A., Vollrath, D., Enns, G. M., & Cowan, T. M. (2020) · PLoS ONE · doi:10.1371/journal.pone.0240517 · Cited by 16 · see citing works

Detection of PPARδ agonists GW1516 and GW0742 and their metabolites in human urine

Sobolevsky, T. G., Dikunets, M. A., Sukhanova, I. I., Virus, E. D., & Rodchenkov, G. M. (2012) · Drug Testing and Analysis · doi:10.1002/dta.1413 · Cited by 16 · see citing works

Skeletal muscle dysfunction in chronic obstructive pulmonary disease

Shrikrishna, D., & Hopkinson, N. S. (2009) · Respiratory Medicine COPD Update · doi:10.1016/j.rmedu.2009.01.002 · Cited by 16 · see citing works

Obesity Drug Update: The Lost Decade?

Yao, F., & MacKenzie, R. G. (2010) · Pharmaceuticals · doi:10.3390/ph3123494 · Cited by 16 · see citing works

AICAR promotes endothelium-independent vasorelaxation by activating AMP-activated protein kinase via increased ZMP and decreased ATP/ADP ratio in aortic smooth muscle

Pyla, R., Hartney, T. J., & Segar, L. (2022) · Journal of Basic and Clinical Physiology and Pharmacology · doi:10.1515/jbcpp-2021-0308 · Cited by 13 · see citing works

PPARgamma agonist pioglitazone does not enhance performance in mice

Sanchis‐Gomar, F., Pareja-Galeano, H., & Martinez-Bello, V. E. (2013) · Drug Testing and Analysis · doi:10.1002/dta.1587 · Cited by 13 · see citing works

Impaired Musculoskeletal Response to Age and Exercise in PPARβ−/− Diabetic Mice

Fu, H., Desvergne, B., Ferrari, S., & Bonnet, N. (2014) · Endocrinology · doi:10.1210/en.2014-1585 · Cited by 13 · see citing works

Pioglitazone and Deoxyribonucleoside Combination Treatment Increases Mitochondrial Respiratory Capacity in m.3243A>G MELAS Cybrid Cells

Burgin, H. J., Sanchez, M. I. G. L., Smith, C. M., Trounce, I. A., & McKenzie, M. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21062139 · Cited by 12 · see citing works

Sitagliptin improves diastolic cardiac function but not cardiorespiratory fitness in adults with type 2 diabetes

Scalzo, R. L., Rafferty, D., Schauer, I. E., Huebschmann, A. G., Cree‐Green, M., Reusch, J. E. B., & Regensteiner, J. G. (2019) · Journal of Diabetes and its Complications · doi:10.1016/j.jdiacomp.2019.05.002 · Cited by 12 · see citing works

Identifying Gaps in Real-World Management of Diabetes in Nigeria: A Subset Analysis of Cross-Sectional Wave-7 Data from the International Diabetes Management Practices Study

Kolawole, B. A., Anumah, F. O., & Unachukwu, C. (2022) · Journal of Diabetes Mellitus · doi:10.4236/jdm.2022.124023 · Cited by 10 · see citing works

Personalised exercise prescription: Finding the best for our patients

Tuka, V., & Linhart, A. (2019) · European Journal of Preventive Cardiology · doi:10.1177/2047487319884376 · Cited by 10 · see citing works

Effect of increased physical activity on fructose-induced glycemic response in healthy individuals

Bidwell, A. J., Fairchild, T. J., Wang, L., Keslacy, S., & Kanaley, J. A. (2014) · European Journal of Clinical Nutrition · doi:10.1038/ejcn.2014.90 · Cited by 7 · see citing works

Does innovation in obesity drugs affect stock markets? An event study analysis

Pérez–Rodríguez, J. V., & López‐Valcárcel, B. G. (2012) · Gaceta Sanitaria · doi:10.1016/j.gaceta.2011.07.028 · Cited by 7 · see citing works

Stimulating Mitochondrial Biogenesis with Deoxyribonucleosides Increases Functional Capacity in ECHS1-Deficient Cells

Burgin, H. J., Crameri, J. J., Stojanovski, D., Sanchez, M. I. G. L., Ziemann, M., & McKenzie, M. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms232012610 · Cited by 6 · see citing works

Exercise pills for cardiometabolic health cannot mimic the exercise milieu

Plaza‐Florido, A., Lindholm, M. E., Carrera‐Bastos, P., Santos‐Lozano, A., Valenzuela, P. L., Fiuza‐Luces, C., Radom‐Aizik, S., & Lucı́a, A. (2025) · Trends in Endocrinology and Metabolism · doi:10.1016/j.tem.2025.07.005 · Cited by 5 · see citing works

Deleterious effects of physical inactivity on the hippocampus: New insight into the increasing prevalence of stress-related depression

Nishijima, T., & Kita, I. (2015) · The Journal of Physical Fitness and Sports Medicine · doi:10.7600/jpfsm.4.253 · Cited by 5 · see citing works

The Role of Exercise in the Quality of Life in Patients After Pancreatectomy: A Prospective Randomized Controlled Trial

Katsourakis, A., Vrabas, I. S., Papanikolaou, V., Apostolidis, S., Chatzis, I., & Noussios, G. (2018) · Journal of Clinical Medicine Research · doi:10.14740/jocmr3675 · Cited by 4 · see citing works

1,5-anhydro-D-fructose induces anti-aging effects on aging-associated brain diseases by increasing 5’-adenosine monophosphate-activated protein kinase activity via the peroxisome proliferator-activated receptor-γ co-activator-1α/brain-derived neurotrophic factor pathway

Kikuchi, K., Otsuka, S., Takada, S., Nakanishi, K., Setoyama, K., Sakakima, H., Tanaka, E., & Maruyama, I. (2023) · Aging · doi:10.18632/aging.205228 · Cited by 4 · see citing works

Physical enhancement of human performance: Is law keeping pace with science?

Solomon, L. M., Mordkoff, D. S., & Noll, R. C. (2009) · Gender Medicine · doi:10.1016/j.genm.2009.04.008 · Cited by 4 · see citing works

Kidney betaine: A potential broad spectrum exercise mimetic against aging

Wang, H., Yang, X., Jin, C., Bowen, T. S., & Xiao, J. (2025) · Journal of sport and health science/Journal of Sport and Health Science · doi:10.1016/j.jshs.2025.101092 · Cited by 3 · see citing works

Activité physique et maladie rénale chronique : quelles relations en 2013 ?

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Urine levels of 5-aminoimidazole-4-carboxamide riboside (AICAR) in patients with type 2 diabetes

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