SHANK3,the Synapse, and Autism

Shank3 mutant mice display autistic-like behaviours and striatal dysfunction

Peça, J., Feliciano, C., Ting, J. T., Wang, W., Wells, M. F., Venkatraman, T. N., Lascola, C. D., Fu, Z., & Feng, G. (2011) · Nature · doi:10.1038/nature09965 · Cited by 1,570 · see citing works

Etiological heterogeneity in autism spectrum disorders: More than 100 genetic and genomic disorders and still counting

Betancur, C. (2011) · Brain Research · doi:10.1016/j.brainres.2010.11.078 · Cited by 954 · see citing works

De novo mutations in the gene encoding the synaptic scaffolding protein <i>SHANK3</i> in patients ascertained for schizophrenia

Gauthier, J., Champagne, N., Lafrenière, R. G., Xiong, L., Spiegelman, D., Brustein, E., Lapointe, M., Peng, H., Côté, M., Noreau, A., et al. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0906232107 · Cited by 369 · see citing works

Excess of de novo deleterious mutations in genes associated with glutamatergic systems in nonsyndromic intellectual disability

Hamdan, F. F., Gauthier, J., Araki, Y., Lin, D.-T., Yoshizawa, Y., Higashi, K., Park, A.-R., Spiegelman, D., Dobrzeniecka, S., Piton, A., et al. (2011) · The American Journal of Human Genetics · doi:10.1016/j.ajhg.2011.02.001 · Cited by 349 · see citing works

The cytoskeletal scaffold Shank3 is recruited to pathogen-induced actin rearrangements

Huett, A. S., Leong, J. M., Podolsky, D. K., & Xavier, R. J. (2009) · Experimental Cell Research · doi:10.1016/j.yexcr.2009.04.003 · Cited by 16 · see citing works

Functional annotation of the human brain methylome identifies tissue-specific epigenetic variation across brain and blood

Davies, M. N., Volta, M., Pidsley, R., Lunnon, K., Dixit, A., Lovestone, S., Coarfa, C., Harris, R. A., Milosavljevic, A., Troakes, C., et al. (2012) · Genome Biology · doi:10.1186/gb-2012-13-6-r43 · Cited by 630 · see citing works

Reduced Excitatory Neurotransmission and Mild Autism-Relevant Phenotypes in Adolescent <i>Shank3</i> Null Mutant Mice

Yang, M., Bozdagi, O., Scattoni, M. L., Wöhr, M., Roullet, F. I., Katz, A. M., Abrams, D. N., Kalikhman, D., Simon, H., Woldeyohannes, L., et al. (2012) · The Journal of Neuroscience · doi:10.1523/jneurosci.6107-11.2012 · Cited by 369 · see citing works

Genetic Removal of p70 S6 Kinase 1 Corrects Molecular, Synaptic, and Behavioral Phenotypes in Fragile X Syndrome Mice

Bhattacharya, A., Kaphzan, H., Alvarez-Dieppa, A. C., Murphy, J. P., Pierre, P., & Klann, E. (2012) · Neuron · doi:10.1016/j.neuron.2012.07.022 · Cited by 316 · see citing works

Developmental Trajectories in Children With and Without Autism Spectrum Disorders: The First 3 Years

Landa, R. J., Gross, A. L., Stuart, E. A., & Faherty, A. (2013) · Child Development · doi:10.1111/j.1467-8624.2012.01870.x · Cited by 316 · see citing works

Synaptic Signaling in Learning and Memory

Kennedy, M. B. (2016) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a016824 · Cited by 270 · see citing works

Reduction in parvalbumin expression not loss of the parvalbumin-expressing GABA interneuron subpopulation in genetic parvalbumin and shank mouse models of autism

Filice, F., Vörckel, K. J., Sungur, A. Ö., Wöhr, M., & Schwaller, B. (2016) · Molecular Brain · doi:10.1186/s13041-016-0192-8 · Cited by 240 · see citing works

Neurobiological Sequelae of Witnessing Stressful Events in Adult Mice

Warren, B. L., Vialou, V. F., Iñiguez, S. D., Alcantara, L. F., Wright, K. N., Feng, J., Kennedy, P. J., LaPlant, Q., Shen, L., Nestler, E. J., et al. (2013) · Biological Psychiatry · doi:10.1016/j.biopsych.2012.06.006 · Cited by 222 · see citing works

Epigenetic understanding of gene-environment interactions in psychiatric disorders: a new concept of clinical genetics

Kubota, T., Miyake, K., & Hirasawa, T. (2012) · Clinical Epigenetics · doi:10.1186/1868-7083-4-1 · Cited by 157 · see citing works

Novel Shank3 mutant exhibits behaviors with face validity for autism and altered striatal and hippocampal function

Jaramillo, T. C., Speed, H. E., Xuan, Z., Reimers, J. M., Escamilla, C. O., Weaver, T. P., Liu, S., Filonova, I., & Powell, C. M. (2017) · Autism Research · doi:10.1002/aur.1664 · Cited by 119 · see citing works

Neuronal L-Type Calcium Channel Signaling to the Nucleus Requires a Novel CaMKIIα-Shank3 Interaction

Perfitt, T. L., Wang, X., Dickerson, M. T., Stephenson, J. R., Nakagawa, T., Jacobson, D. A., & Colbran, R. J. (2020) · The Journal of Neuroscience · doi:10.1523/jneurosci.0893-19.2020 · Cited by 54 · see citing works

First-degree relatives of young children with autism spectrum disorders: Some gender aspects

Eriksson, M. A., Westerlund, J., Anderlid, B. M., Gillberg, C., & Fernell, E. (2012) · Research in Developmental Disabilities · doi:10.1016/j.ridd.2012.03.025 · Cited by 43 · see citing works

Distinct molecular programs regulate synapse specificity in cortical inhibitory circuits

Favuzzi, E., Deogracias, R., Marques–Smith, A., Maeso, P. A., Jézéquel, J., Exposito-Alonso, D., Balia, M., Kroon, T., Hinojosa, A. J., Maraver, E. F., et al. (2019) · Science · doi:10.1126/science.aau8977 · Cited by 217 · see citing works

Identification of a protein related to tubulin in the postsynaptic

Feit, H. W., & COTMANt, C. W. (2016)

The postsynaptic density: a possible role in long-lasting effects in the central nervous system.

Siekevitz, P. (1985) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.82.10.3494 · Cited by 197 · see citing works

Extending computational models of astrocyte-neuron interactions with biochemical mechanisms on the postsynaptic terminal

Saudargienė, A., Manninen, T., Havela, R., & Linne, M. (2015) · BMC Neuroscience · doi:10.1186/1471-2202-16-s1-p148

Quantal analysis and synaptic anatomy--integrating two views of hippocampal plasticity.

Lisman, J., & Harris, K. (1993) · Trends in Neurosciences · doi:10.1016/0166-2236(93)90122-3 · Cited by 271 · see citing works