Seborrheic Dermatitis

Naldi, Luigi; Rebora, Alfredo

doi:10.1056/nejmcp0806464

Cited by 188Nail Diseases and TreatmentsDermatology and Skin DiseasesDermatological diseases and infestations

Seborrheic Dermatitis

Naldi, Luigi, Rebora, Alfredo·2009·New England Journal of Medicine

DOI 10.1056/nejmcp0806464

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Abstract

A 35-year-old man reports itching, redness, and scaling in his scalp, eyebrows, and external auditory canal. He has tried several over-the-counter dandruff shampoos, with only temporary relief, and is increasingly embarrassed by this problem. Physical examination reveals greasy scaling on the scalp and erythema with yellowish scales in the nasolabial creases. How should his case be managed?

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SD may be associated with sex hormones such as androgens.
“Men are affected more frequently than women (3.0% vs. 2.6%) in all age groups, suggesting that SD may be associated with sex hormones such as androgens [1,3,8].”
From Seborrheic Dermatitis and Dandruff: A Comprehensive Review (2015) · cites this paper as [8]
In adolescents and adults, SD affects the scalp and other seborrheic areas on the face, upper-chest, axillae, and inguinal folds.
“In adolescents and adults, SD affects the scalp and other seborrheic areas on the face, upper-chest, axillae, and inguinal folds [4,7,8].”
From Seborrheic Dermatitis and Dandruff: A Comprehensive Review (2015) · cites this paper as [8]
Men are affected more frequently than women (3.0% vs. 2.6%) in all age groups.
“Men are affected more frequently than women (3.0% vs. 2.6%) in all age groups, suggesting that SD may be associated with sex hormones such as androgens [1,3,8].”
From Seborrheic Dermatitis and Dandruff: A Comprehensive Review (2015) · cites this paper as [8]
The main differential diagnosis of SD and dandruff includes psoriasis, atopic dermatitis, tinea capitis, rosacea, and systemic lupus erythematous (SLE).
“The main differential diagnosis of SD and dandruff includes psoriasis, atopic dermatitis (mainly in the pediatric form of SD), tinea capitis, rosacea, and systemic lupus erythematous (SLE) [3,7,8] (Table 2).”
From Seborrheic Dermatitis and Dandruff: A Comprehensive Review (2015) · cites this paper as [8]
Psoriasis lesions are thicker and present as plaques sharply limited with silvery white scales.
“While psoriasis can affect similar locations as SD, typical lesions in psoriasis are thicker and present as plaques sharply limited with silvery white scales [8,32].”
From Seborrheic Dermatitis and Dandruff: A Comprehensive Review (2015) · cites this paper as [8]

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Authors: Naldi, L., & Rebora, A.
Affiliations: Centro Studi GISED (IT)
ORCID: Naldi, Luigi
Rebora, Alfredo
Venue: New England Journal of Medicine
Publisher: Massachusetts Medical Society
Published: 2009-01-22
Volume: 360
Issue: 4
Pages: 387-396
ISSN: 0028-4793 (ISSN-L)
1533-4406
DOI: 10.1056/nejmcp0806464
OpenAlex: W2465777630
Cited by: 188
References: 42
Citations by year: 2026: 11 · 2025: 3 · 2024: 9 · 2023: 15 · 2022: 8 · 2021: 7 · 2020: 10 · 2019: 17 · 2018: 3 · 2017: 9 · 2016: 12 · 2015: 16 · 2014: 15 · 2013: 18 · 2012: 12
FWCI: 1.37
Type: journal article
Language: en
Open access: closed
Locations: New England Journal of Medicine (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Epidemiology › Nail Diseases and Treatments
Health Sciences › Medicine › Dermatology › Dermatology and Skin Diseases
Health Sciences › Medicine › Infectious Diseases › Dermatological diseases and infestations
Keywords: seborrheic dermatitis, scalp, dandruff, external auditory canal, erythema, scaling, treatment management
MeSH terms: Administration, Topical, Adrenal Cortex Hormones, Antifungal Agents, Humans, Ketoconazole, Dermatitis, Seborrheic, Practice Guidelines as Topic

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Seborrheic Dermatitis

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