Bacterial Diarrhea
Abstract
A 47-year-old man reports a 1-week history of diarrhea, with grossly bloody stools for the past 5 days. He reports no history of travel, contacts with sick persons, or underlying gastrointestinal disease. How should he be evaluated and treated for an infectious cause of his illness?
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Most non-inflammatory diarrhea is caused by Clostridium food poisoning, ETEC, Staphylococcus, Vibrio cholerae, viruses (norovirus and rotavirus), and parasites (Giardia and Cryptosporidium).
“non-inflammatory diarrhea is caused by Clostridium food poisoning, ETEC, Staphylococcus, Vibrio cholerae, viruses (norovirus and rotavirus), and parasites (Giardia and Cryptosporidium) [8]”
From Guideline for the Antibiotic Use in Acute Gastroenteritis (2019) · cites this paper as [8]
Most acute inflammatory diarrhea is caused by Campylobacter, C. difficile, enterohemorrhagic E. coli, EIEC, Salmonella, Shigella, and Yersinia.
“Most acute inflammatory diarrhea is caused by Campylobacter, C. difficile, enterohemorrhagic E. coli (EHEC hereafter), EIEC, Salmonella, Shigella, and Yersinia”
From Guideline for the Antibiotic Use in Acute Gastroenteritis (2019) · cites this paper as [8]
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“Diarrhea in prisons can be accounted for by norovirus, C. difficile, Shigella, Cryptosporidium, Giardia, Salmonella, STEC, and rotavirus, and diarrhea in childcare services may have been caused by rotavirus, Cryptosporidium, Giardia, Shigella, or STEC.”
BackgroundInfluentialClinical Guideline for the Diagnosis and Treatment of Gastrointestinal Infections
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- Authors
- DuPont, H. L.
- Affiliations
- Baylor St. Luke's Medical Center (US)
- Corresponding author
- DuPont, Herbert L.
- ORCID
- DuPont, Herbert L.
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 2009-10-15
- Volume
- 361
- Issue
- 16
- Pages
- 1560-1569
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W2439575626
- Cited by
- 155
- References
- 47
- Citations by year
- 2026: 3 · 2025: 7 · 2024: 5 · 2023: 5 · 2022: 8 · 2021: 7 · 2020: 7 · 2019: 11 · 2018: 8 · 2017: 9 · 2016: 9 · 2015: 11 · 2014: 9 · 2013: 14 · 2012: 15
- FWCI
- 1.86
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- New England Journal of Medicine (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institute of Diabetes and Digestive and Kidney Diseases (DK56338, P30DK056338)
- Topics
- Life Sciences › Agricultural and Biological Sciences › Food Science › Salmonella and Campylobacter epidemiology
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Clinical Biochemistry › Bacterial Identification and Susceptibility Testing
- Health Sciences › Medicine › Infectious Diseases › Clostridium difficile and Clostridium perfringens research
- Keywords
- bacterial diarrhea, bloody diarrhea, infectious diarrhea, differential diagnosis, clinical evaluation, treatment, traveler's diarrhea
- MeSH terms
- Bacterial Infections, Cross Infection, Diarrhea, Dysentery, Escherichia coli, Foodborne Diseases, Humans, Male, Middle Aged, Travel, Practice Guidelines as Topic, Shiga Toxins
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