The GPR54 Gene as a Regulator of Puberty

Seminara, Stephanie B., Messager, Sophie, Chatzidaki, Emmanouella E., Thresher, Rosemary R., Acierno, James S., Shagoury, Jenna K., Bo-Abbas, Yousef, Kuohung, Wendy, Schwinof, Kristine M., Hendrick, Alan G., Zahn, Dirk, Dixon, John, Kaiser, Ursula B., Slaugenhaupt, Susan A., Gusella, James F., O'Rahilly, Stephen, Carlton, Mark B.L., Crowley, William F., Aparicio, Samuel A.J.R., Colledge, William H.·2003·New England Journal of Medicine

DOI 10.1056/nejmoa035322

Cited by (1,009)

Items 401–500 of 1,009

Kisspeptin receptor agonist has therapeutic potential for female reproductive disorders
Ali Abbara, Pei Chia Eng, Maria Phylactou, Sophie A. Clarke, Rachel E. Richardson, Charlene M. Sykes, Chayarndorn Phumsatitpong, Edouard Mills, Manish Modi, Chioma N. Izzi‐Engbeaya et al. · 2020 · Journal of Clinical Investigation
Human GnRH Deficiency: A Unique Disease Model to Unravel the Ontogeny of GnRH Neurons
Ravikumar Balasubramanian, Andrew A. Dwyer, Stephanie Beth Seminara, Nelly Pitteloud, Ursula B. Kaiser, William F. Crowley · 2010 · Neuroendocrinology
Insulin-Like Growth Factor-I Activates KiSS-1 Gene Expression in the Brain of the Prepubertal Female Rat
Jill K. Hiney, Vinod K. Srivastava, Michelle D. Pine, W. Les Dees · 2008 · Endocrinology
Separate effects of sex hormones and sex chromosomes on brain structure and function revealed by high-resolution magnetic resonance imaging and spatial navigation assessment of the Four Core Genotype mouse model
Corre, Christina, Friedel, Miriam, Vousden, Dulcie A., Metcalf, Ariane, Spring, Shoshana, Qiu, Lily R., Lerch, Jason P., Palmert, Mark R. · 2016 · Brain Structure and Function
Shift in Kiss1 Cell Activity Requires Estrogen Receptor α
Renata Frazão, Roberta M. Cravo, José Donato, Dhirender V. Ratra, Deborah J. Clegg, Joel Keith Elmquist, Jeffrey Marc Zigman, Kevin W. Williams, Carol Fuzeti Elias · 2013 · Journal of Neuroscience
Evidence That Down Regulation of Hypothalamic KiSS‐1 Expression is Involved in the Negative Feedback Action of Testosterone to Regulate Luteinising Hormone Secretion in the Adult Male Rhesus Monkey (Macaca mulatta)
M Shibata, Robert L. Friedman, Suresh Ramaswamy, Tony M. Plant · 2007 · Journal of Neuroendocrinology
KiSS-1 system and reproduction: Comparative aspects and roles in the control of female gonadotropic axis in mammals
Juan Roa, Manuel Tena‐Sempere · 2007 · General and Comparative Endocrinology
Impaired Fibroblast Growth Factor Receptor 1 Signaling as a Cause of Normosmic Idiopathic Hypogonadotropic Hypogonadism
Taneli Raivio, Yisrael Sidis, Lacey Plummer, Huaibin Chen, Jinghong Ma, Abir Mukherjee, Elka E. Jacobson-Dickman, Richard Quinton, Guy Van Vliet, Hélène B. Lavoie et al. · 2009 · The Journal of Clinical Endocrinology & Metabolism
Kisspeptin regulates prolactin release through hypothalamic dopaminergic neurons
Szawka, Raphael E., Ribeiro, Aline B., Leite, Cristiane M., Helena, Cleyde V. V., Franci, Celso R., Anderson, Greg M., Hoffman, Gloria E., Anselmo-Franci, Janete A. · 2010 · Endocrinology
Melatonin Controls Seasonal Breeding by a Network of Hypothalamic Targets
Florent G. Revel, Mireille Masson‐Pévet, Paul Pévet, Jens Damsgaard Mikkelsen, Valérie Simonneaux · 2009 · Neuroendocrinology
A novel neuropeptide in suppressing luteinizing hormone release in goldfish, Carassius auratus
Yun Liu, Shuisheng Li, Qi Xing, Wenyi Zhou, Xiaochun Liu, Haoran Lin, Yong Zhang, Christopher H.K. Cheng · 2013 · Molecular and Cellular Endocrinology
Kisspeptins and the control of gonadotropin secretion in male and female rodents
Juan Roa, Juan Manuel Castellano, Victor Manuel Navarro, David J. Handelsman, L. Pinilla, Manuel Tena‐Sempere · 2008 · Peptides
Kisspeptin Regulates Gonadotroph and Somatotroph Function in Nonhuman Primate Pituitary via Common and Distinct Signaling Mechanisms
Raul Miguel Luque, José Córdoba‐Chacón, Manuel David Gahete, Victor Manuel Navarro, Manuel Tena‐Sempere, Rhonda Denise Kineman, Justo Pastor Castano · 2011 · Endocrinology
Control of GnRH secretion: One step back
Iain James Clarke · 2011 · Frontiers in Neuroendocrinology
The role of KiSS-1 in the regulation of puberty in higher primates
Tony M. Plant · 2006 · European Journal of Endocrinology
Kisspeptins and RFRP-3 Act in Concert to Synchronize Rodent Reproduction with Seasons
Valérie Simonneaux, Caroline Ancel, Vincent‐Joseph Poirel, François Gauer · 2013 · Frontiers in Neuroscience
Kisspeptin stimulates progesterone secretion via the Erk1/2 mitogen-activated protein kinase signaling pathway in rat luteal cells
Jing Peng, Min Tang, Bao-Ping Zhang, Peng Zhang, Ting Zhong, Teng Zong, Bei Yang, Haibin Kuang · 2013 · Fertility and Sterility
The kisspeptin (KiSS-1)/GPR54 system in cancer biology
Angeliki Makri, Nikolaos Pissimissis, Peter Lembessis, Constantin Polychronakos, Michael Koutsilieris · 2008 · Cancer Treatment Reviews
Physiology of Gnrh and Gonadotropin Secretion
Pedro Marques, Karolina Skorupskaite, Jyothis Thomas George, Richard A. Anderson · 2015
Minipuberty of human infancy – A window of opportunity to evaluate hypogonadism and differences of sex development?
Christoffer Højrup Renault, Lise Aksglæde, Ditte Wøjdemann, Anna Hansen, Rikke Beck Jensen, Anders Juul · 2020 · Annals of Pediatric Endocrinology & Metabolism
Subacute cadmium exposure disrupts the hypothalamic-pituitary-gonadal axis, leading to polycystic ovarian syndrome and premature ovarian failure features in female rats
Charles S. da Costa, Thiago Fernandes de Oliveira, Leandro Ceotto Freitas‐Lima, Alessandra Simão Padilha, Maiara Krause, Maria Tereza Weitzel Dias Carneiro, Breno Souza Salgado, Jones Bernardes Graceli · 2020 · Environmental Pollution
Kisspeptin Increases γ-Aminobutyric Acidergic and Glutamatergic Transmission Directly to Gonadotropin-Releasing Hormone Neurons in an Estradiol-Dependent Manner
Justyna Pielecka-Fortuna, Suzanne M. Moenter · 2009 · Endocrinology
Characterization of GnRH Pulse Generator Activity in Male Mice Using GCaMP Fiber Photometry
Han, Su Young, Kane, Grace, Cheong, Isaiah, Herbison, Allan E · 2019 · Endocrinology
Gonadotropin-releasing hormone plasticity: A comparative perspective
Tyler John Stevenson, Thomas P. Hahn, Scott A. MacDougall‐Shackleton, Gregory F. Ball · 2012 · Frontiers in Neuroendocrinology
The Roles of Kisspeptin System in the Reproductive Physiology of Fish With Special Reference to Chub Mackerel Studies as Main Axis
Hirofumi Ohga, Sethu Selvaraj, Michiya Matsuyama · 2018 · Frontiers in Endocrinology
MKRN3 inhibits the reproductive axis through actions in kisspeptin-expressing neurons
Ana Paula Abreu, Carlos A. Toro, Yong Bhum Song, Victor Manuel Navarro, Martha A. Bosch, Ayşegül Eren, Joy N. Liang, Rona Stephanie Carroll, Ana Cláudia Latronico, Oline K. Rønnekleiv et al. · 2020 · Journal of Clinical Investigation
What controls the timing of puberty? An update on progress from genetic investigation
Zofia K. Z. Gajdos, Joel N. Hirschhorn, Mark R. Palmert · 2009 · Current Opinion in Endocrinology Diabetes and Obesity
Update 1 of: Over One Hundred Peptide-Activated G Protein-Coupled Receptors Recognize Ligands with Turn Structure
Gloria Ruiz‐Gómez, Joel D. A. Tyndall, Bernhard Pfeiffer, Giovanni Abbenante, David P. Fairlie · 2010 · Chemical Reviews
Effects of intrauterine undernutrition on hypothalamic Kiss1 expression and the timing of puberty in female rats
Takeshi Iwasa, Toshiya Matsuzaki, Masahiro Murakami, Shigeki FUJISAWA, Riyo Kinouchi, Ganbat Gereltsetseg, Akira Kuwahara, Toshiyuki Yasui, Minoru Irahara · 2010 · The Journal of Physiology
Effects of high-fat diet-induced obesity and diabetes on Kiss1 and GPR54 expression in the hypothalamic–pituitary–gonadal (HPG) axis and peripheral organs (fat, pancreas and liver) in male rats
Monika Dudek, Pawel Antoni Kolodziejski, Ewa Pruszyńska‐Oszmałek, Maciej Sassek, Kamil Ziarniak, Krzysztof W. Nowak, Joanna Helena Sliwowska · 2016 · Neuropeptides
A comparison of the neuroendocrine mechanisms underlying the initiation of the preovulatory LH surge in the human, Old World monkey and rodent
Tony M. Plant · 2012 · Frontiers in Neuroendocrinology
20 YEARS OF LEPTIN: Leptin and reproduction: past milestones, present undertakings, and future endeavors
Farid F Chehab · 2014 · Journal of Endocrinology
Leptin is not the Critical Signal for Kisspeptin or Luteinising Hormone Restoration During Exit from Negative Energy Balance
Cadence A. True, Melissa Ann Kirigiti, Paul Kievit, Kevin L. Grove, M. Susan Smith · 2011 · Journal of Neuroendocrinology
Caloric restriction: Impact upon pituitary function and reproduction
Bronwen Martin, Erin Golden, Olga D. Carlson, Josephine Mary Egan, Mark P. Mattson, Stuart R. Maudsley · 2008 · Ageing Research Reviews
Alterations in Hypothalamic KiSS-1 System in Experimental Diabetes: Early Changes and Functional Consequences
Juan Manuel Castellano, Victor Manuel Navarro, Juan Roa, Rafael Pineda, Miguel Angel Sanchez-Garrido, David García-Galiano, Eva Vigo, Carlos Diéguez, E. Aguilar, L. Pinilla et al. · 2008 · Endocrinology
Neonatal exposure to genistein adversely impacts the ontogeny of hypothalamic kisspeptin signaling pathways and ovarian development in the peripubertal female rat
Sandra Maria Losa-Ward, Karina L. Todd, Alana W. Sullivan, Jinyan Cao, Jillian A. Mickens, Heather B. Patisaul · 2010 · Reproductive Toxicology
Developmental Changes in the Expression of Kisspeptin mRNA in Rat Hypothalamus
Ken Takumi, Norio Iijima, Hitoshi Ozawa · 2010 · Journal of Molecular Neuroscience
Endocrine Dysregulation in Anorexia Nervosa Update
Karen Klahr Miller · 2011 · The Journal of Clinical Endocrinology & Metabolism
Molecular basis of normal and pathological puberty: from basic mechanisms to clinical implications
Jesús Argente, Leo Dunkel, Ursula B. Kaiser, Ana Cláudia Latronico, Alejandro Lomniczi, Leandro Soriano‐Guillén, Manuel Tena‐Sempere · 2023 · The Lancet Diabetes & Endocrinology
Suppression of the GnRH Pulse Generator by Neurokinin B Involves a κ-Opioid Receptor-Dependent Mechanism
Pasha Grachev, X. F. Li, James S. Kinsey‐Jones, Angelique di Domenico, Robert Peter Millar, Stafford Louis Lightman, K. T. O'Byrne · 2012 · Endocrinology
The use of GnRH agonists in precocious puberty
Dick Mul, Ieuan Arwel Hughes · 2008 · European Journal of Endocrinology
Genetic Evidence for Multifactorial Control of the Reproductive Axis in Zebrafish
Yun Liu, Haipei Tang, Rui Xie, Shuisheng Li, Xiaochun Liu, Haoran Lin, Yong Zhang, Christopher H.K. Cheng · 2017 · Endocrinology
Discovering Genes Essential to the Hypothalamic Regulation of Human Reproduction Using a Human Disease Model: Adjusting to Life in the “-Omics” Era
Maria I. Stamou, Kimberly H. Cox, William F. Crowley · 2015 · Endocrine Reviews · Retracted
Metastin and its G protein-coupled receptor, GPR54: Critical pathway modulating GnRH secretion
Stephanie Beth Seminara · 2005 · Frontiers in Neuroendocrinology
Estrogen Regulates KiSS1 Gene Expression through Estrogen Receptor α and SP Protein Complexes
Li, Dali, Mitchell, Dianne, Luo, Jian, Yi, Zhengfang, Cho, Sung-Gook, Guo, Jingjing, Li, Xiaoying, Ning, Guang, Wu, Xiushan, Liu, Mingyao · 2007 · Endocrinology
Leptin-Responsive GABAergic Neurons Regulate Fertility through Pathways That Result in Reduced Kisspeptinergic Tone
Cecilia Martin, Victor Manuel Navarro, Serap Aynur Simavlı, Linh Vong, Rona Stephanie Carroll, Bradford B. Lowell, Ursula B. Kaiser · 2014 · Journal of Neuroscience
Increased Neurokinin B (Tac2) Expression in the Mouse Arcuate Nucleus Is an Early Marker of Pubertal Onset with Differential Sensitivity to Sex Steroid-Negative Feedback than Kiss1
John C. Gill, Victor Manuel Navarro, Cecilia Kwong, Sekoni D. Noel, Cecilia Martin, Shuyun Xu, Donald K. Clifton, Rona Stephanie Carroll, Robert A. Steiner, Ursula B. Kaiser · 2012 · Endocrinology
Novel mechanisms for the metabolic control of puberty: implications for pubertal alterations in early-onset obesity and malnutrition
Maria Jesus Vazquez, Inmaculada Velasco, Manuel Tena‐Sempere · 2019 · Journal of Endocrinology
Multi- and Transgenerational Outcomes of an Exposure to a Mixture of Endocrine-Disrupting Chemicals (EDCs) on Puberty and Maternal Behavior in the Female Rat
David López Rodríguez, Carlos Francisco Aylwin, Virginia Delli, Elena Sevrin, Marzia Campanile, Marion J. Martin, Delphine Franssen, Arlette Gérard, Silvia Blacher, Ezio Tirelli et al. · 2021 · Environmental Health Perspectives
Activation of Neuropeptide FF Receptors by Kisspeptin Receptor Ligands
Shinya Oishi, Ryosuke Misu, Kenji Tomita, Shohei Setsuda, Ryo Masuda, Hiroaki Ohno, Yousuke Naniwa, Nahoko Ieda, Naoko Inoue, Satoshi Ohkura et al. · 2010 · ACS Medicinal Chemistry Letters
Kisspeptin and GPR54: Discovery of a Novel Pathway in Reproduction
Stephanie Beth Seminara, W F Crowley · 2008 · Journal of Neuroendocrinology
Corticotrophin-releasing factor and stress-induced inhibition of the gonadotrophin-releasing hormone pulse generator in the female
X.F. Li, A. M. I. Knox, K.T. O'Byrne · 2010 · Brain Research
Central Mechanism Controlling Pubertal Onset in Mammals: A Triggering Role of Kisspeptin
Yoshihisa Uenoyama, Naoko Inoue, Sho Nakamura, Hiroko Tsukamura · 2019 · Frontiers in Endocrinology
Opposite Roles of Estrogen Receptor (ER)-α and ERβ in the Modulation of Luteinizing Hormone Responses to Kisspeptin in the Female Rat: Implications for the Generation of the Preovulatory Surge
Juan Roa, Eva Vigo, Juan Manuel Castellano, Francisco Gaytán, Victor Manuel Navarro, E. Aguilar, Fred A. Dijcks, A. G. H. EDERVEEN, L. Pinilla, Paula I. van Noort et al. · 2008 · Endocrinology
Hypothalamic hamartoma with epilepsy: Review of endocrine comorbidity
Victor S. Harrison, Oliver J. Oatman, John Kerrigan · 2017 · Epilepsia
RFamide peptides as mediators in environmental control of GnRH neurons
Ishwar S. Parhar, Satoshi Ogawa, Takashi Kitahashi · 2012 · Progress in Neurobiology
Neuroendocrine, gonadal, placental, and obstetric phenotypes in patients with IHH and mutations in the G-protein coupled receptor, GPR54
J. Carl Pallais, Yousef Y Bo-Abbas, Nelly Pitteloud, William F. Crowley, Stephanie Beth Seminara · 2006 · Molecular and Cellular Endocrinology
Transgenic mouse models to study Gpr54/kisspeptin physiology
William Henry Colledge · 2008 · Peptides
Neonatal Lipopolysaccharide Exposure Delays Puberty and Alters Hypothalamic Kiss1 and Kiss1r mRNA Expression in the Female Rat
A. M. I. Knox, X. F. Li, James S. Kinsey‐Jones, E. S. Wilkinson, Xueqing Wu, Yewsong Cheng, S. R. Milligan, Stafford Louis Lightman, K. T. O’Byrne · 2009 · Journal of Neuroendocrinology
RFamide Peptides: Structure, Function, Mechanisms and Pharmaceutical Potential
Maria Findeisen, Daniel Rathmann, Annette Gabriele Beck‐Sickinger · 2011 · Pharmaceuticals
Sexual differentiation and development of forebrain reproductive circuits
Sheila J. Semaan, Alexander S. Kauffman · 2010 · Current Opinion in Neurobiology
Early Onset of Puberty: Tracking Genetic and Environmental Factors
Anne‐Simone Parent, Grégory Rasier, Arlette Gérard, Sabine Heger, Christian Ludwig Roth, Claudio Alberto Mastronardi, Heike Jung, Sergio R. Ojeda, Jean‐Pierre Bourguignon · 2005 · Hormone Research in Paediatrics
Neuroanatomy of the Human Hypothalamic Kisspeptin System
Erik Hrabovszky · 2013 · Neuroendocrinology
Functional Significance of GnRH and Kisspeptin, and Their Cognate Receptors in Teleost Reproduction
Renjitha Gopurappilly, Satoshi Ogawa, Ishwar S. Parhar · 2013 · Frontiers in Endocrinology
Amygdala Kisspeptin Neurons: Putative Mediators of Olfactory Control of the Gonadotropic Axis
Rafael Pineda, Fabrice Plaisier, Robert Peter Millar, Mike Ludwig · 2016 · Neuroendocrinology
Environmental obesogen tributyltin chloride leads to abnormal hypothalamic-pituitary-gonadal axis function by disruption in kisspeptin/leptin signaling in female rats
Gabriela Cavati Sena, Leandro Ceotto Freitas‐Lima, Eduardo Merlo, Priscila L. Podratz, Julia F.P. de Araújo, Poliane A.A. Brandão, Maria Tereza Weitzel Dias Carneiro, Marina Campos Zicker, Adaliene Versiani Matos Ferreira, Christina Maeda Takiya et al. · 2017 · Toxicology and Applied Pharmacology
Neonatal and juvenile exposure to perfluorooctanoate (PFOA) and perfluorooctane sulfonate (PFOS): Advance puberty onset and kisspeptin system disturbance in female rats
Guizhen Du, Jialei Hu, Zhenyao Huang, Mingming Yu, Chuncheng Lu, Xinru Wang, Di Wu · 2018 · Ecotoxicology and Environmental Safety
Circulating MKRN3 levels decline prior to pubertal onset and through puberty: a longitudinal study of healthy girls
Hagen, Casper P., Sørensen, Kaspar, Mieritz, Mikkel G., Johannsen, Trine Holm, Almstrup, Kristian, Juul, Anders · 2015 · The Journal of Clinical Endocrinology & Metabolism
Neuroendocrine mechanisms underlying estrogen positive feedback and the LH surge
Alexander S. Kauffman · 2022 · Frontiers in Neuroscience
Evidence That Dopamine Acts via Kisspeptin to Hold GnRH Pulse Frequency in Check in Anestrous Ewes
Robert L. Goodman, Matthew J. Maltby, Robert Peter Millar, Stanley M. Hileman, Casey C Nestor, Brant Whited, Ashlie S. Tseng, Lique M. Coolen, Michael N. Lehman · 2012 · Endocrinology
Kisspeptin: Beyond the Brain
Moshmi M. Bhattacharya, Andy Vi Babwah · 2015 · Endocrinology
Kisspeptin expression in the brain: Catalyst for the initiation of puberty
J. T. Smith, Iain James Clarke · 2007 · Reviews in Endocrine and Metabolic Disorders
New Concepts on the Control of the Onset of Puberty
Sergio R. Ojeda, Alejandro Lomniczi, Ursula S. Sandau, Valérie Matagne · 2009 · Endocrine development
Sex Steroids, Growth Hormone, Leptin and the Pubertal Growth Spurt
Alan David Rogol · 2009 · Endocrine development
Identification of gonadotropin-inhibitory hormone in the zebra finch (Taeniopygia guttata): Peptide isolation, cDNA cloning and brain distribution
Yasuko Tobari, Norio Iijima, Kenta Tsunekawa, Tomohiro Osugi, Kazuo Okanoya, Kazuyoshi Tsutsui, Hitoshi Ozawa · 2010 · Peptides
Administration of Kisspeptin‐54 into Discrete Regions of the Hypothalamus Potently Increases Plasma Luteinising Hormone and Testosterone in Male Adult Rats
Michael Patterson, Kevin G. Murphy, Emily L. Thompson, Suhani Patel, Mohammad A. Ghatei, Stephen Robert Bloom · 2006 · Journal of Neuroendocrinology
Adiponectin inhibits KISS1 gene transcription through AMPK and specificity protein-1 in the hypothalamic GT1-7 neurons
Junping Wen, Chune Liu, Wenkai Bi, Yating Hu, Qingshi Chen, Huibing Huang, Jixing Liang, Liantao Li, Lixiang Lin, Gang Chen · 2012 · Journal of Endocrinology
Molecular coevolution of kisspeptins and their receptors from fish to mammals
Haet Nim Um, Ji Man Han, Jong‐Ik Hwang, Sung In Hong, Hubert Vaudry, Jae Young Seong · 2010 · Annals of the New York Academy of Sciences
Molecular and Environmental Mechanisms Regulating Puberty Initiation: An Integrated Approach
Sarantis Livadas, George Panagiotis Chrousos · 2019 · Frontiers in Endocrinology
The KISS1 metastasis suppressor: mechanistic insights and clinical utility
T. Nash Kevin · 2006 · Frontiers in bioscience
Genetics basis for GnRH-dependent pubertal disorders in humans
Letícia Ferreira Gontijo Silveira, Ericka Barbosa Trarbach, Ana Cláudia Latronico · 2010 · Molecular and Cellular Endocrinology
Haploinsufficiency of Dmxl2, Encoding a Synaptic Protein, Causes Infertility Associated with a Loss of GnRH Neurons in Mouse
Brooke K. Tata, Lukas Huijbregts, Sandrine Jacquier, Zsolt Csaba, Emmanuelle Génin, Vincent Meyer, Sofia Leka, Joëlle Dupont, Perrine Charles, Didier Chevenne et al. · 2014 · PLoS Biology
New understandings of the genetic basis of isolated idiopathic central hypogonadism
Marco Bonomi, Domenico Vladimiro Libri, Fabiana Guizzardi, Elena Guarducci, Elisabetta Maiolo, Elisa Pignatti, Roberta Asci, Luca Persani · 2011 · Asian Journal of Andrology
Role of puberty in multiple sclerosis risk and course
Tanuja Chitnis · 2013 · Clinical Immunology
Expression of kisspeptins in the brain and pituitary of the european sea bass (Dicentrarchus labrax)
Sebastián Escobar, Alicia Felip, M. Guéguen, Silvia Zanuy, Manuel Carrillo, Olivier Kah, Arianna Servili · 2012 · The Journal of Comparative Neurology
The Physiology and Pathology of the Female Reproductive Axis
Serdar Ekrem Bulun, Eli Y. Adashi, Serdar E. Bulun · 2007 · Time to knit
The regulation of reproductive neuroendocrine function by insulin and insulin-like growth factor-1 (IGF-1)
Wolfe, Andrew, Divall, Sara, Wu, Sheng · 2014 · Frontiers in Neuroendocrinology
Prepubertal exposure to an oestrogenic mycotoxin zearalenone induces central precocious puberty in immature female rats through the mechanism of premature activation of hypothalamic kisspeptin-GPR54 signaling
Rong Yang, Yimei Wang, Li Zhang, Zengming Zhao, Jun Zhao, Shuangqing Peng · 2016 · Molecular and Cellular Endocrinology
Kisspeptins and the neuroendocrine control of reproduction: Recent progress and new frontiers in kisspeptin research
Verónica Sobrino, María Soledad Avendaño, Cecilia Perdices-López, Manuel Jiménez-Puyer, Manuel Tena‐Sempere · 2022 · Frontiers in Neuroendocrinology
Developmental and Steroidogenic Effects on the Gene Expression of RFamide Related Peptides and their Receptor in the Rat Brain and Pituitary Gland
Janette H. Quennell, M. Z. Rizwan, Hana-Lee Relf, Greg M. Anderson · 2010 · Journal of Neuroendocrinology
The KISS1 metastasis suppressor: A good night kiss for disseminated cancer cells
Beck, Benjamin H., Welch, Danny R. · 2010 · European Journal of Cancer
Differential ovarian expression of KiSS‐1 and GPR‐54 during the estrous cycle and photoperiod induced recrudescence in Siberian hamsters (Phodopus sungorus)
ASHA R. SHAHED, Kelly A. Young · 2008 · Molecular Reproduction and Development
Kisspeptin stimulation of insulin secretion: mechanisms of action in mouse islets and rats
James E. Bowe, Aileen King, James S. Kinsey‐Jones, V. Foot, X. F. Li, K. T. O’Byrne, Shanta Jean Persaud, Peter M. Jones · 2009 · Diabetologia
High-Fat Diet Increases LH Pulse Frequency and Kisspeptin-Neurokinin B Expression in Puberty-Advanced Female Rats
Xiao Feng Li, Yuan Shao Lin, James S. Kinsey‐Jones, Kevin T. O'Byrne · 2012 · Endocrinology
Biosocial Development and Delinquent Involvement
Kevin M. Beaver, JOHN PAUL WRIGHT · 2005 · Youth Violence and Juvenile Justice
Primary cilia enhance kisspeptin receptor signaling on gonadotropin-releasing hormone neurons
Andrew Koemeter-Cox, Thomas W. Sherwood, Jill A. Green, Robert A. Steiner, Nicolas F. Berbari, Bradley K. Yoder, Alexander S. Kauffman, Paula C. Monsma, Anthony Brown, Candice C. Askwith et al. · 2014 · Proceedings of the National Academy of Sciences
Expression of a Tumor-Related Gene Network Increases in the Mammalian Hypothalamus at the Time of Female Puberty
Christian Ludwig Roth, Claudio Alberto Mastronardi, Alejandro Lomniczi, Hollis Wright, Ricardo Cabrera, Alison E. Mungenast, Sabine Heger, Heike Jung, Christopher Dubay, Sergio R. Ojeda · 2007 · Endocrinology
Kisspeptin Neurons and Estrogen–Estrogen Receptor α Signaling: Unraveling the Mystery of Steroid Feedback System Regulating Mammalian Reproduction
Yoshihisa Uenoyama, Naoko Inoue, Sho Nakamura, Hiroko Tsukamura · 2021 · International Journal of Molecular Sciences
Kisspeptin modulates fertilization capacity of mouse spermatozoa
Meng-Chieh Hsu, Jyun-Yuan Wang, Yue‐Jia Lee, De‐Shien Jong, Kuan‐Hao Tsui, Chih‐Hsien Chiu · 2014 · Reproduction
On the value of seasonal mammals for identifying mechanisms underlying the control of food intake and body weight
Francis J. P. Ebling · 2014 · Hormones and Behavior