A Randomized Trial of Therapies for Type 2 Diabetes and Coronary Artery Disease

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1. Appropriate Use Criteria for Coronary Revascularization and Trends in Utilization, Patient Selection, and Appropriateness of Percutaneous Coronary Intervention
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2. ESC Guidelines on diabetes, pre-diabetes, and cardiovascular diseases developed in collaboration with the EASD – Summary
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3. Cardiovascular outcome trials of glucose-lowering drugs or strategies in type 2 diabetes
   Holman, Rury R, Sourij, Harald, Califf, Robert M · 2014 · The Lancet
4. 8. Cardiovascular Disease and Risk Management
   American Diabetes Association · 2014 · Diabetes Care
5. Outcomes with various drug eluting or bare metal stents in patients with diabetes mellitus: mixed treatment comparison analysis of 22 844 patient years of follow-up from randomised trials
   S. Bangalore, Sunil K. Kumar, Mario V. Fusaro, N. Amoroso, A. Kirtane, R. Byrne, D. Williams, J. Slater, D. Cutlip, F. Feit · 2012 · British medical journal
6. Calcification in atherosclerosis
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7. Insulin Resistance as a Physiological Defense Against Metabolic Stress: Implications for the Management of Subsets of Type 2 Diabetes
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8. DPP-4 Inhibition by Sitagliptin Improves the Myocardial Response to Dobutamine Stress and Mitigates Stunning in a Pilot Study of Patients With Coronary Artery Disease
   Philip A. Read, Fakhar Z. Khan, Patrick M. Heck, Stephen Paul Hoole, David P. Dutka · 2010 · Circulation Cardiovascular Imaging
9. 9. Cardiovascular Disease and Risk Management
   American Diabetes Association · 2017 · Diabetes Care
10. 2024 AHA/ACC/ACS/ASNC/HRS/SCA/SCCT/SCMR/SVM Guideline for Perioperative Cardiovascular Management for Noncardiac Surgery
    Annemarie Thompson, Kirsten E. Fleischmann, Nathaniel Rosso Smilowitz, Lisa de las Fuentes, Debabrata Mukherjee, Niti R. Aggarwal, Faraz S. Ahmad, Robert B. Allen, S. Elissa Altin, Andrew David Auerbach et al. · 2024 · Journal of the American College of Cardiology
11. Comparison of coronary artery bypass surgery and percutaneous coronary intervention in patients with diabetes: a meta-analysis of randomised controlled trials
    Subodh Verma, Michael E. Farkouh, Bobby Yanagawa, DAVID H. FITCHETT, Muhammad Rauf Ahsan, Marc Ruel, Sachin Sud, Milan Gupta, Shantanu Singh, Nandini Gupta et al. · 2013 · The Lancet Diabetes & Endocrinology
12. Metformin Effects on the Heart and the Cardiovascular System: A Review of Experimental and Clinical Data
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13. Percutaneous Coronary Intervention Versus Optimal Medical Therapy in Stable Coronary Artery Disease
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14. Coronary Artery Disease and Diabetes Mellitus
    Aronson, Doron, Edelman, Elazer R. · 2014 · Cardiology Clinics
15. Initial Coronary Stent Implantation With Medical Therapy vs Medical Therapy Alone for Stable Coronary Artery Disease
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16. The Lancet Commission on rethinking coronary artery disease: moving from ischaemia to atheroma
    Sarah J. Zaman, Jason H. Wasfy, Vikas Kapil, Boback Ziaeian, William Anthony Parsonage, Sira Sriswasdi, Tim Chico, Davide Capodanno, Róisín Colleran, Nadia R. Sutton et al. · 2025 · The Lancet
17. Comparative Definitions for Moderate-Severe Ischemia in Stress Nuclear, Echocardiography, and Magnetic Resonance Imaging
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18. Thiazolidinedione safety
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19. Inducible Myocardial Ischemia and Outcomes in Patients With Coronary Artery Disease and Left Ventricular Dysfunction
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20. Ensuring the integrity of clinical practice guidelines: a tool for protecting patients
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21. Intensive glycemic control has no impact on the risk of heart failure in type 2 diabetic patients: Evidence from a 37,229 patient meta-analysis
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22. Baseline stress myocardial perfusion imaging results and outcomes in patients with stable ischemic heart disease randomized to optimal medical therapy with or without percutaneous coronary intervention
    Leslee J. Shaw, William S. Weintraub, David Joel Maron, Pamela M. Hartigan, Rory Hachamovitch, James K. Min, Marcin R. Dada, G.B. John Mancini, Sean W. Hayes, Robert A. O’Rourke et al. · 2012 · American Heart Journal
23. Diabetes Mellitus and Heart Failure
    Michael Lehrke, Nikolaus Marx · 2017 · The American Journal of Medicine
24. Effects of Percutaneous Coronary Intervention on Death and Myocardial Infarction Stratified by Stable and Unstable Coronary Artery Disease
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25. Routine Revascularization Versus Initial Medical Therapy for Stable Ischemic Heart Disease
    Sripal Bangalore, David Joel Maron, Gregg W. Stone, Judith S. Hochman · 2020 · Circulation
26. Design and baseline characteristics of participants in the R esearching cardiovascular E vents with a W eekly IN cretin in D iabetes ( REWIND ) trial on the cardiovascular effects of dulaglutide
    Hertzel C. Gerstein, Helen Martina Colhoun, Gilles R. Dagenais, Rafael Díaz, Mark C Lakshmanan, Prem S Pais, Jeffrey L. Probstfield, Matthew C. Riddle, Lars Rydén, Denis Xavier et al. · 2017 · Diabetes Obesity and Metabolism
27. Myocardial blood flow reserve assessed by positron emission tomography myocardial perfusion imaging identifies patients with a survival benefit from early revascularization
    Krishna Patel, John A. Spertus, Paul S. Chan, Brett Wesley Sperry, Firas J. Al Badarin, Kevin F. Kennedy, Randall C. Thompson, James A. Case, A. Iain McGhie, Timothy M. Bateman · 2019 · European Heart Journal
28. Peripheral Endothelial Function and Cardiovascular Events in High‐Risk Patients
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29. Metformin revisited: A critical review of the benefit–risk balance in at-risk patients with type 2 diabetes
    André Jacques Scheen, Nicolas Paquot · 2013 · Diabetes & Metabolism
30. Impact of glycemic control strategies on the progression of diabetic peripheral neuropathy in the bypass angioplasty revascularization investigation 2 diabetes (BARI 2D) cohort
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31. Sulfonylureas: A New Look at Old Therapy
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32. Canadian Cardiovascular Society Guidelines for the Diagnosis and Management of Stable Ischemic Heart Disease
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33. Trends in Aortic Valve Replacement for Elderly Patients in the United States, 1999-2011
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34. Results of a reevaluation of cardiovascular outcomes in the RECORD trial
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35. Percutaneous Coronary Intervention Versus Coronary Bypass Surgery in United States Veterans With Diabetes
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36. Risk Factor Control for Coronary Artery Disease Secondary Prevention in Large Randomized Trials
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37. Selective Referral Using CCTA Versus Direct Referral for Individuals Referred to Invasive Coronary Angiography for Suspected CAD
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38. Sex differences in mechanisms, presentation and management of ischaemic heart disease
    Filippo Crea, Irma Battipaglia, Felicita Andreotti · 2015 · Atherosclerosis
39. Glucose-lowering drugs or strategies, atherosclerotic cardiovascular events, and heart failure in people with or at risk of type 2 diabetes: an updated systematic review and meta-analysis of randomised cardiovascular outcome trials
    Ghosh-Swaby, Olivia R, Goodman, Shaun G, Leiter, Lawrence A, Cheng, Alice, Connelly, Kim A, Fitchett, David, Jüni, Peter, Farkouh, Michael E, Udell, Jacob A · 2020 · The Lancet Diabetes & Endocrinology
40. Impact of left ventricular function and the extent of ischemia and scar by stress myocardial perfusion imaging on prognosis and therapeutic risk reduction in diabetic patients with coronary artery disease: Results from the Bypass Angioplasty Revascularization Investigation 2 Diabetes (BARI 2D) trial
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41. Survival After Invasive or Conservative Management of Stable Coronary Disease
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42. Clinical Practice Guideline on management of patients with diabetes and chronic kidney disease stage 3b or higher (eGFR <45 mL/min)
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43. Cardiac mortality in patients randomised to elective coronary revascularisation plus medical therapy or medical therapy alone: a systematic review and meta-analysis
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44. Evolving concepts of the vulnerable atherosclerotic plaque and the vulnerable patient: implications for patient care and future research
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45. Cardiac computed tomography and myocardial perfusion scintigraphy for risk stratification in asymptomatic individuals without known cardiovascular disease: a position statement of the Working Group on Nuclear Cardiology and Cardiac CT of the European Society of Cardiology
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46. 2021 AHA/ACC/ASE/CHEST/SAEM/SCCT/SCMR Guideline for the Evaluation and Diagnosis of Chest Pain: Executive Summary
    Martha Gulati, Phillip David Levy, Debabrata Mukherjee, Ezra A. Amsterdam, Deepak L. Bhatt, Kim K. Birtcher, Ron Blankstein, Jack H. Boyd, Renée P. Bullock-Palmer, Theresa Conejo et al. · 2021 · Journal of the American College of Cardiology
47. Novel HDL-directed pharmacotherapeutic strategies
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48. 2011 ACCF/AHA/SCAI guideline for percutaneous coronary intervention
    Glenn N. Levine, Eric Bates, James C. Blankenship, Steven R. Bailey, John A. Bittl, Bojan Cercek, Charles E. Chambers, Stephen G. Ellis, Robert A. Guyton, Steven M. Hollenberg et al. · 2011 · Catheterization and Cardiovascular Interventions
49. Type 2 diabetes mellitus and heart failure, a scientific statement from the American Heart Association and Heart Failure Society of America
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50. Cardiovascular outcome trials in type 2 diabetes and the sulphonylurea controversy: Rationale for the active-comparator CAROLINA trial
    Julio Rosenstock, Nikolaus Marx, Steven E. Kahn, Bernard Zinman, John J.P. Kastelein, John M. Lachin, Erich Bluhmki, Sanjay Dhanji Patel, Odd-Erik Johansen, H.J. Woerle · 2013 · Diabetes and Vascular Disease Research
51. Primary and Secondary Prevention of Cardiovascular Diseases: A Practical Evidence-Based Approach
    James Henry O’Keefe, Maia D. Carter, Carl J. Lavie · 2009 · Mayo Clinic Proceedings
52. Thiazolidinedione Drugs and Cardiovascular Risks
    Sanjay Kaul, Ann F. Bolger, David M. Herrington, Robert Patrick Giugliano, Robert H. Eckel · 2010 · Journal of the American College of Cardiology
53. Myocardial Infarction in the ISCHEMIA Trial
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54. Diagnosis and management of atherosclerotic cardiovascular disease in chronic kidney disease: a review
    Roy O. Mathew, Sripal Bangalore, Michael P. Lavelle, Patricia A. Pellikka, Mandeep S. Sidhu, William E. Boden, Arif Asif · 2016 · Kidney International
55. 2021 AHA/ACC/ASE/CHEST/SAEM/SCCT/SCMR Guideline for the Evaluation and Diagnosis of Chest Pain
    Martha Gulati, Phillip David Levy, Debabrata Mukherjee, Ezra A. Amsterdam, Deepak L. Bhatt, Kim K. Birtcher, Ron Blankstein, Jack H. Boyd, Renée P. Bullock-Palmer, Theresa Conejo et al. · 2021 · Journal of cardiovascular computed tomography
56. Baseline Characteristics and Risk Profiles of Participants in the ISCHEMIA Randomized Clinical Trial
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57. The impact of medication adherence on clinical outcomes of coronary artery disease: A meta-analysis
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58. Prognosis in the era of comparative effectiveness research: Where is nuclear cardiology now and where should it be?
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59. JCS 2022 Guideline Focused Update on Diagnosis and Treatment in Patients With Stable Coronary Artery Disease
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60. Comprehensive Cardiovascular Risk Factor Control Improves Survival
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61. Is Glucose Control Important for Prevention of Cardiovascular Disease in Diabetes?
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62. Effects of Severe Hypoglycemia on Cardiovascular Outcomes and Death in the Veterans Affairs Diabetes Trial
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63. Meta-analysis: Effects of Percutaneous Coronary Intervention Versus Medical Therapy on Angina Relief
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64. Initial Invasive Versus Conservative Management of Stable Ischemic Heart Disease in Patients With a History of Heart Failure or Left Ventricular Dysfunction
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65. Endothelial dysfunction in (pre)diabetes: Characteristics, causative mechanisms and pathogenic role in type 2 diabetes
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66. Trends in postacute myocardial infarction management and mortality in patients with diabetes. A population-based study from 1995 to 2001
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67. Diagnosis and Management of Stable Angina
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68. Effects of Optimal Medical Treatment With or Without Coronary Revascularization on Angina and Subsequent Revascularizations in Patients With Type 2 Diabetes Mellitus and Stable Ischemic Heart Disease
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69. Computed Fractional Flow Reserve (FFTCT) Derived from Coronary CT Angiography
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70. Paclitaxel-Eluting versus Everolimus-Eluting Coronary Stents in Diabetes
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71. Do sulphonylureas still have a place in clinical practice?
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72. Stress Myocardial Perfusion Imaging for Assessing Prognosis: An Update
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73. Early diabetic nephropathy in type 1 diabetes
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74. Compliance With Guideline-Directed Medical Therapy in Contemporary Coronary Revascularization Trials
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75. Timing of In-Hospital Coronary Artery Bypass Graft Surgery for Non–ST-Segment Elevation Myocardial Infarction Patients
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76. Microvascular and Macrovascular Disease and Risk for Major Peripheral Arterial Disease in Patients With Type 2 Diabetes
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77. Management of Left Main Coronary Artery Disease
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78. Thiazolidinedione Drugs and Cardiovascular Risks
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79. 2024 Clinical practice guidelines for Stable coronary artery disease
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80. Unstable Angina and Non–ST Elevation Myocardial Infarction
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81. Cardiac hybrid imaging
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82. Detection of silent myocardial ischemia in asymptomatic patients with diabetes: results of a randomized trial and meta-analysis assessing the effectiveness of systematic screening
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83. Prognostic Impact of Chronic Total Occlusions
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84. Evaluation and Management of Patients With Stable Angina: Beyond the Ischemia Paradigm
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85. The Ets-1 transcription factor is involved in the development and invasion of malignant melanoma
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86. 10. Cardiovascular Disease and Risk Management: Standards of Care in Diabetes—2026
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87. Extent of Myocardial Ischemia on Positron Emission Tomography and Survival Benefit With Early Revascularization
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88. Rationale and design of the Women's Ischemia Trial to Reduce Events in Nonobstructive CAD (WARRIOR) trial
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89. The design and rationale of the Saxagliptin Assessment of Vascular Outcomes Recorded in patients with diabetes mellitus–Thrombolysis in Myocardial Infarction (SAVOR-TIMI) 53 Study
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90. The prognostic impact of concomitant coronary artery bypass grafting during aortic valve surgery: Implications for revascularization in the transcatheter era
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91. Diabetes and Metabolism
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92. Current concepts on coronary revascularization in diabetic patients
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93. Atherosclerosis evaluation and cardiovascular risk estimation using coronary computed tomography angiography
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94. Value of Exercise ECG for Risk Stratification in Suspected or Known CAD in the Era of Advanced Imaging Technologies
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95. Heart Failure Outcomes in Clinical Trials of Glucose-Lowering Agents in Patients with Diabetes
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96. Impact of the SYNTAX scores I and II in patients with diabetes and multivessel coronary disease: a pooled analysis of patient level data from the SYNTAX, PRECOMBAT, and BEST trials
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97. Serious Cardiovascular Outcomes in Diabetes
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98. Prognostic Implications of Type 2 Diabetes Mellitus in Ischemic and Nonischemic Heart Failure
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99. PPARγand Its Role in Cardiovascular Diseases
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100. Cardiovascular Disease and Risk Management: Review of the American Diabetes Association Standards of Medical Care in Diabetes 2018
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