9. Cardiovascular Disease and Risk Management

Empagliflozin, Cardiovascular Outcomes, and Mortality in Type 2 Diabetes

Zinman, B., Wanner, C., Lachin, J. M., Fitchett, D., Bluhmki, E., Hantel, S., Mattheus, M., Devins, T., Johansen, O. E., Woerle, H. J., et al. (2015) · New England Journal of Medicine · doi:10.1056/nejmoa1504720 · Cited by 12,315 · see citing works

Age-specific relevance of usual blood pressure to vascular mortality: a meta-analysis of individual data for one million adults in 61 prospective studies

(2002) · The Lancet · doi:10.1016/s0140-6736(02)11911-8 · Cited by 10,266 · see citing works

European Guidelines on cardiovascular disease prevention in clinical practice (version 2012)

Authors/Task Force Members:, Perk, J., De Backer, G., Gohlke, H., Graham, I., Reiner, Ž., Verschuren, M., Albus, C., Benlian, P., Boysen, G., et al. (2012) · European Heart Journal · doi:10.1093/eurheartj/ehs092 · Cited by 8,490 · see citing works

2014 Evidence-Based Guideline for the Management of High Blood Pressure in Adults: Report From the Panel Members Appointed to the Eighth Joint National Committee (JNC 8)

James, P. A., Oparil, S., Carter, B. L., Cushman, W. C., Dennison-Himmelfarb, C., Handler, J., Lackland, D. T., LeFevre, M. L., MacKenzie, T. D., Ogedegbe, O., et al. (2014) · JAMA · doi:10.1001/jama.2013.284427 · Cited by 7,950 · see citing works

Liraglutide and Cardiovascular Outcomes in Type 2 Diabetes

Marso, S. P., Daniels, G. H., Brown-Frandsen, K., Kristensen, P., Mann, J. F. E., Nauck, M. A., Nissen, S. E., Pocock, S., Poulter, N. R., Ravn, L. S., et al. (2016) · New England Journal of Medicine · doi:10.1056/nejmoa1603827 · Cited by 7,629 · see citing works

Effects of losartan on renal and cardiovascular outcomes in patients with type 2 diabetes and nephropathy

Brenner, B. M., Cooper, M. E., de Zeeuw, D., Keane, W. F., Mitch, W. E., Parving, H.-H., Remuzzi, G., Snapinn, S. M., Zhang, Z., & Shahinfar, S. (2001) · New England Journal of Medicine · doi:10.1056/nejmoa011161 · Cited by 7,493 · see citing works

Efficacy and safety of cholesterol-lowering treatment: prospective meta-analysis of data from 90 056 participants in 14 randomised trials of statins

(2005) · The Lancet · doi:10.1016/s0140-6736(05)67394-1 · Cited by 6,848 · see citing works

A Randomized Trial of Intensive versus Standard Blood-Pressure Control

The SPRINT Research Group (2015) · New England Journal of Medicine · doi:10.1056/nejmoa1511939 · Cited by 6,325 · see citing works

Effects of intensive blood-pressure lowering and low-dose aspirin in patients with hypertension: principal results of the hypertension optimal treatment (HOT) randomised trial

Hansson, L., Zanchetti, A., Carruthers, S. G., Dahlöf, B., Elmfeldt, D., Julius, S., Ménard, J., Rahn, K. H., Wedel, H., & Westerling, S. (1998) · The Lancet · doi:10.1016/s0140-6736(98)04311-6 · Cited by 5,728 · see citing works

Effects on Blood Pressure of Reduced Dietary Sodium and the Dietary Approaches to Stop Hypertension (DASH) Diet

Sacks, F. M., Svetkey, L. P., Vollmer, W. M., Appel, L. J., Bray, G. A., Harsha, D., Obarzanek, E., Conlin, P. R., Miller, E. R., Simons-Morton, D. G., et al. (2001) · New England Journal of Medicine · doi:10.1056/nejm200101043440101 · Cited by 5,638 · see citing works

Intensive versus Moderate Lipid Lowering with Statins after Acute Coronary Syndromes

Cannon, C. P., Braunwald, E., McCabe, C. H., Rader, D. J., Rouleau, J. L., Belder, R., Joyal, S. V., Hill, K. A., Pfeffer, M. A., & Skene, A. M. (2004) · New England Journal of Medicine · doi:10.1056/nejmoa040583 · Cited by 4,938 · see citing works

Optimal Medical Therapy with or without PCI for Stable Coronary Disease

Boden, W. E., O'Rourke, R. A., Teo, K. K., Hartigan, P. M., Maron, D. J., Kostuk, W. J., Knudtson, M., Dada, M., Casperson, P., Harris, C. L., et al. (2007) · New England Journal of Medicine · doi:10.1056/nejmoa070829 · Cited by 4,699 · see citing works

Ezetimibe Added to Statin Therapy after Acute Coronary Syndromes

Cannon, C. P., Blazing, M. A., Giugliano, R. P., McCagg, A., White, J. A., Theroux, P., Darius, H., Lewis, B. S., Ophuis, T. O., Jukema, J. W., et al. (2015) · New England Journal of Medicine · doi:10.1056/nejmoa1410489 · Cited by 4,487 · see citing works

Secondary prevention of macrovascular events in patients with type 2 diabetes in the PROactive Study (PROspective pioglitAzone Clinical Trial In macroVascular Events): a randomised controlled trial

Dormandy, J. A., Charbonnel, B., Eckland, D. J., Erdmann, E., Massi-Benedetti, M., Moules, I. K., Skene, A. M., Tan, M. H., Lefèbvre, P. J., Murray, G. D., et al. (2005) · The Lancet · doi:10.1016/s0140-6736(05)67528-9 · Cited by 4,129 · see citing works

Primary prevention of cardiovascular disease with atorvastatin in type 2 diabetes in the Collaborative Atorvastatin Diabetes Study (CARDS): multicentre randomised placebo-controlled trial

Colhoun, H. M., Betteridge, D. J., Durrington, P. N., Hitman, G. A., W Neil, H. A., Livingstone, S. J., Thomason, M. J., Mackness, M. I., Charlton-Menys, V., & Fuller, J. H. (2004) · The Lancet · doi:10.1016/s0140-6736(04)16895-5 · Cited by 3,755 · see citing works

Aspirin in the primary and secondary prevention of vascular disease: collaborative meta-analysis of individual participant data from randomised trials

(2009) · The Lancet · doi:10.1016/s0140-6736(09)60503-1 · Cited by 3,675 · see citing works

Effects of intensive blood-pressure control in type 2 diabetes mellitus

(2010) · New England Journal of Medicine · doi:10.1056/nejmoa1001286 · Cited by 3,598 · see citing works

Telmisartan, ramipril, or both in patients at high risk for vascular events

(2008) · New England Journal of Medicine · doi:10.1056/nejmoa0801317 · Cited by 3,502 · see citing works

Effect of a multifactorial intervention on mortality in type 2 diabetes

Gæde, P., Lund-Andersen, H., Parving, H.-H., & Pedersen, O. (2008) · New England Journal of Medicine · doi:10.1056/nejmoa0706245 · Cited by 3,489 · see citing works

Saxagliptin and cardiovascular outcomes in patients with type 2 diabetes mellitus

Scirica, B. M., Bhatt, D. L., Braunwald, E., Steg, P. G., Davidson, J., Hirshberg, B., Ohman, P., Frederich, R., Wiviott, S. D., Hoffman, E. B., et al. (2013) · New England Journal of Medicine · doi:10.1056/nejmoa1307684 · Cited by 3,470 · see citing works

Effects of long-term fenofibrate therapy on cardiovascular events in 9795 people with type 2 diabetes mellitus (the FIELD study): randomised controlled trial

(2005) · The Lancet · doi:10.1016/s0140-6736(05)67667-2 · Cited by 3,284 · see citing works

Effects of ramipril on cardiovascular and microvascular outcomes in people with diabetes mellitus: results of the HOPE study and MICRO-HOPE substudy

(2000) · The Lancet · doi:10.1016/s0140-6736(99)12323-7 · Cited by 3,179 · see citing works

Niacin in Patients with Low HDL Cholesterol Levels Receiving Intensive Statin Therapy

The AIM-HIGH Investigators (2011) · New England Journal of Medicine · doi:10.1056/nejmoa1107579 · Cited by 2,911 · see citing works

Cardiovascular effects of intensive lifestyle intervention in type 2 diabetes

The Look AHEAD Research Group (2013) · New England Journal of Medicine · doi:10.1056/nejmoa1212914 · Cited by 2,908 · see citing works

MRC/BHF Heart Protection Study of cholesterol-lowering with simvastatin in 5963 people with diabetes: a randomised placebo-controlled trial

(2003) · The Lancet · doi:10.1016/s0140-6736(03)13636-7 · Cited by 2,876 · see citing works

Effects of Combination Lipid Therapy in Type 2 Diabetes Mellitus

(2010) · New England Journal of Medicine · doi:10.1056/nejmoa1001282 · Cited by 2,837 · see citing works

The effects of lowering LDL cholesterol with statin therapy in people at low risk of vascular disease: meta-analysis of individual data from 27 randomised trials

Collaborators, C. T. T. (. (2012) · The Lancet · doi:10.1016/s0140-6736(12)60367-5 · Cited by 2,833 · see citing works

Effects of candesartan in patients with chronic heart failure and reduced left-ventricular systolic function taking angiotensin-converting-enzyme inhibitors: the CHARM-Added trial

McMurray, J. J., Östergren, J., Swedberg, K., Granger, C. B., Held, P., Michelson, E. L., Olofsson, B., Yusuf, S., & Pfeffer, M. A. (2003) · The Lancet · doi:10.1016/s0140-6736(03)14283-3 · Cited by 2,604 · see citing works

Effect of Sitagliptin on Cardiovascular Outcomes in Type 2 Diabetes

Green, J. B., Bethel, M. A., Armstrong, P. W., Buse, J. B., Engel, S. S., Garg, J., Josse, R., Kaufman, K. D., Koglin, J., Korn, S., et al. (2015) · New England Journal of Medicine · doi:10.1056/nejmoa1501352 · Cited by 2,577 · see citing works

Statins and risk of incident diabetes: A collaborative meta-analysis of randomised statin trials

Sattar, N., Preiss, D., Murray, H. M., Welsh, P., Buckley, B. M., de Craen, A. J., Seshasai, S. R. K., McMurray, J. J., Freeman, D. J., Jukema, J. W., et al. (2010) · The Lancet · doi:10.1016/s0140-6736(09)61965-6 · Cited by 2,436 · see citing works

Effect of Intensive Compared With Moderate Lipid-Lowering Therapy on Progression of Coronary Atherosclerosis

Nissen, S. E., Tuzcu, E. M., Schoenhagen, P., Brown, B. G., Ganz, P., Vogel, R. A., Crowe, T., Howard, G., Cooper, C. J., Brodie, B. R., et al. (2004) · JAMA · doi:10.1001/jama.291.9.1071 · Cited by 2,358 · see citing works

Platelet Activation and Atherothrombosis

Davì, G., & Patrono, C. (2007) · New England Journal of Medicine · doi:10.1056/nejmra071014 · Cited by 2,135 · see citing works

Role of diabetes in congestive heart failure: The Framingham study

Kannel, W. B., Hjortland, M., & Castelli, W. P. (1974) · The American Journal of Cardiology · doi:10.1016/0002-9149(74)90089-7 · Cited by 2,090 · see citing works

Efficacy of cholesterol-lowering therapy in 18,686 people with diabetes in 14 randomised trials of statins: A meta-analysis

Collaborators, C. T. T. (. (2008) · The Lancet · doi:10.1016/s0140-6736(08)60104-x · Cited by 2,081 · see citing works

Benazepril plus amlodipine or hydrochlorothiazide for hypertension in high-risk patients

Jamerson, K., Weber, M. A., Bakris, G. L., Dahlöf, B., Pitt, B., Shi, V., Hester, A., Gupte, J., Gatlin, M., & Velazquez, E. J. (2008) · New England Journal of Medicine · doi:10.1056/nejmoa0806182 · Cited by 2,065 · see citing works

Effects of a fixed combination of perindopril and indapamide on macrovascular and microvascular outcomes in patients with type 2 diabetes mellitus (the ADVANCE trial): a randomised controlled trial

Patel, A. (2007) · The Lancet · doi:10.1016/s0140-6736(07)61303-8 · Cited by 2,054 · see citing works

A Randomized Trial of Therapies for Type 2 Diabetes and Coronary Artery Disease

(2009) · New England Journal of Medicine · doi:10.1056/nejmoa0805796 · Cited by 1,939 · see citing works

Statins for the primary prevention of cardiovascular disease

Taylor, F., Huffman, M. D., Macedo, A. F., Moore, T. H., Burke, M., Davey Smith, G., Ward, K., Ebrahim, S., & Gay, H. C. (2013) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd004816.pub5 · Cited by 1,934 · see citing works

Effects of candesartan on mortality and morbidity in patients with chronic heart failure: the CHARM-Overall programme

Pfeffer, M. A., Swedberg, K. B., Granger, C. B., Held, P., McMurray, J. J. V., Michelson, E. L., Olofsson, B., Östergren, J., & Yusuf, S. (2003) · The Lancet · doi:10.1016/s0140-6736(03)14282-1 · Cited by 1,885 · see citing works

Effects of candesartan in patients with chronic heart failure and reduced left-ventricular systolic function intolerant to angiotensin-converting-enzyme inhibitors: the CHARM-Alternative trial

Granger, C. B., McMurray, J. J., Yusuf, S., Held, P., Michelson, E. L., Olofsson, B., Östergren, J., Pfeffer, M. A., & Swedberg, K. (2003) · The Lancet · doi:10.1016/s0140-6736(03)14284-5 · Cited by 1,686 · see citing works

Cholesterol Lowering With Simvastatin Improves Prognosis of Diabetic Patients With Coronary Heart Disease: A subgroup analysis of the Scandinavian Simvastatin Survival Study (4S)

Pyörälä, K., Pedersen, T. R., Kjekshus, J., Faergeman, O., Olsson, A. G., Thorgeirsson, G., & The Scandinavian Simvastatin Survival Study (4S) Group (1997) · Diabetes Care · doi:10.2337/diacare.20.4.614 · Cited by 1,623 · see citing works

Early Intensive vs a Delayed Conservative Simvastatin Strategy in Patients With Acute Coronary Syndromes: Phase Z of the A to Z Trial

de Lemos, J. A., Blazing, M. A., Wiviott, S. D., Lewis, E. F., Fox, K. A. A., White, H. D., Rouleau, J.-L., Pedersen, T. R., Gardner, L. H., Mukherjee, R., et al. (2004) · JAMA · doi:10.1001/jama.292.11.1307 · Cited by 1,333 · see citing works

Diabetes in Older Adults

Kirkman, M. S., Briscoe, V. J., Clark, N., Florez, H., Haas, L. B., Halter, J. B., Huang, E. S., Korytkowski, M. T., Munshi, M. N., Odegard, P. S., et al. (2012) · Diabetes Care · doi:10.2337/dc12-1801 · Cited by 1,274 · see citing works

Combined angiotensin inhibition for the treatment of diabetic nephropathy

Fried, L. F., Emanuele, N., Zhang, J. H., Brophy, M., Conner, T. A., Duckworth, W., Leehey, D. J., McCullough, P. A., O'Connor, T., Palevsky, P. M., et al. (2013) · New England Journal of Medicine · doi:10.1056/nejmoa1303154 · Cited by 1,169 · see citing works

The Effect of Nisoldipine as Compared with Enalapril on Cardiovascular Outcomes in Patients with Non-Insulin-Dependent Diabetes and Hypertension

Estacio, R. O., Jeffers, B. W., Hiatt, W. R., Biggerstaff, S. L., Gifford, N., & Schrier, R. W. (1998) · New England Journal of Medicine · doi:10.1056/nejm199803053381003 · Cited by 1,158 · see citing works

Angiotensin-converting-enzyme inhibition in stable coronary artery disease

(2004) · New England Journal of Medicine · doi:10.1056/nejmoa042739 · Cited by 1,123 · see citing works

Primary Prevention of Cardiovascular Diseases in People With Diabetes Mellitus

Buse, J. B., Ginsberg, H. N., Bakris, G. L., Clark, N. G., Costa, F., Eckel, R., Fonseca, V., Gerstein, H. C., Grundy, S., Nesto, R. W., et al. (2007) · Diabetes Care · doi:10.2337/dc07-9917 · Cited by 1,055 · see citing works

Long term mortality of mothers and fathers after pre-eclampsia: population based cohort studyPre-eclampsia and cardiovascular disease later in life: who is at risk?

Irgens, H. U., Roberts, J. M., Reisæter, L., Irgens, L. M., & Lie, R. T. (2001) · BMJ · doi:10.1136/bmj.323.7323.1213 · Cited by 1,040 · see citing works

Prognostic Value of Ambulatory and Home Blood Pressures Compared With Office Blood Pressure in the General Population: Follow-Up Results From the Pressioni Arteriose Monitorate e Loro Associazioni (PAMELA) Study

Sega, R., Facchetti, R., Bombelli, M., Cesana, G., Corrao, G., Grassi, G., & Mancia, G. (2005) · Circulation · doi:10.1161/01.cir.0000160923.04524.5b · Cited by 1,009 · see citing works

Effects of the angiotensin-receptor blocker telmisartan on cardiovascular events in high-risk patients intolerant to angiotensin-converting enzyme inhibitors: a randomised controlled trial

(2008) · The Lancet · doi:10.1016/s0140-6736(08)61242-8 · Cited by 1,000 · see citing works

Cardiovascular Events and Their Reduction With Pravastatin in Diabetic and Glucose-Intolerant Myocardial Infarction Survivors With Average Cholesterol Levels: Subgroup Analyses in the Cholesterol And Recurrent Events (CARE) Trial

Goldberg, R. B., Mellies, M. J., Sacks, F. M., Moyé, L. A., Howard, B. V., Howard, W. J., Davis, B. R., Cole, T. G., Pfeffer, M. A., & Braunwald, E. (1998) · Circulation · doi:10.1161/01.cir.98.23.2513 · Cited by 986 · see citing works

Achievement of Goals in U.S. Diabetes Care, 1999–2010

Ali, M. K., Bullard, K. M., Saaddine, J. B., Cowie, C. C., Imperatore, G., & Gregg, E. W. (2013) · New England Journal of Medicine · doi:10.1056/nejmsa1213829 · Cited by 979 · see citing works

The prevention of progression of arterial disease and diabetes (POPADAD) trial: factorial randomised placebo controlled trial of aspirin and antioxidants in patients with diabetes and asymptomatic peripheral arterial disease

Belch, J., MacCuish, A., Campbell, I., Cobbe, S., Taylor, R., Prescott, R., Lee, R., Bancroft, J., MacEwan, S., Shepherd, J., et al. (2008) · BMJ · doi:10.1136/bmj.a1840 · Cited by 977 · see citing works

Evaluation and Treatment of Hypertriglyceridemia: An Endocrine Society Clinical Practice Guideline

Berglund, L., Brunzell, J. D., Goldberg, A. C., Goldberg, I. J., Sacks, F., Murad, M. H., & Stalenhoef, A. F. H. (2012) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2011-3213 · Cited by 887 · see citing works

Blood Pressure Lowering in Type 2 Diabetes: A Systematic Review and Meta-analysis

Emdin, C. A., Rahimi, K., Neal, B., Callender, T., Perkovic, V., & Patel, A. (2015) · JAMA · doi:10.1001/jama.2014.18574 · Cited by 854 · see citing works

Outcome Results of the Fosinopril Versus Amlodipine Cardiovascular Events Randomized Trial (FACET) in Patients With Hypertension and NIDDM

Tatti, P., Pahor, M., Byington, R. P., Mauro, P. D., Guarisco, R., Strollo, G., & Strollo, F. (1998) · Diabetes Care · doi:10.2337/diacare.21.4.597 · Cited by 843 · see citing works

Cardiovascular benefits and diabetes risks of statin therapy in primary prevention: an analysis from the JUPITER trial

Ridker, P. M., Pradhan, A., MacFadyen, J. G., Libby, P., & Glynn, R. J. (2012) · The Lancet · doi:10.1016/s0140-6736(12)61190-8 · Cited by 816 · see citing works

Cardiac Outcomes After Screening for Asymptomatic Coronary Artery Disease in Patients With Type 2 Diabetes: The DIAD Study: A Randomized Controlled Trial

Young, L. H., Wackers, F. J. T., Chyun, D. A., Davey, J. A., Barrett, E. J., Taillefer, R., Heller, G. V., Iskandrian, A. E., Wittlin, S. D., Filipchuk, N., et al. (2009) · JAMA · doi:10.1001/jama.2009.476 · Cited by 809 · see citing works

Diabetes as a risk factor for stroke in women compared with men: A systematic review and meta-analysis of 64 cohorts, including 775 385 individuals and 12 539 strokes

Peters, S. A. E., Huxley, R. R., & Woodward, M. (2014) · The Lancet · doi:10.1016/s0140-6736(14)60040-4 · Cited by 805 · see citing works

Detection of Silent Myocardial Ischemia in Asymptomatic Diabetic Subjects

Wackers, F. J. T., Young, L. H., Inzucchi, S. E., Chyun, D. A., Davey, J. A., Barrett, E. J., Taillefer, R., Wittlin, S. D., Heller, G. V., Filipchuk, N., et al. (2004) · Diabetes Care · doi:10.2337/diacare.27.8.1954 · Cited by 791 · see citing works

Heart failure and mortality outcomes in patients with type 2 diabetes taking alogliptin versus placebo in EXAMINE: a multicentre, randomised, double-blind trial

Zannad, F., Cannon, C. P., Cushman, W. C., Bakris, G. L., Menon, V., Perez, A. T., Fleck, P. R., Mehta, C. R., Kupfer, S., Wilson, C., et al. (2015) · The Lancet · doi:10.1016/s0140-6736(14)62225-x · Cited by 757 · see citing works

Diabetes and hypertension: a position statement by the American Diabetes Association

de Boer, I. H., Bangalore, S., Benetos, A., Davis, A. M., Michos, E. D., Muntner, P., Rossing, P., Zoungas, S., & Bakris, G. (2017) · Diabetes Care · doi:10.2337/dci17-0026 · Cited by 714 · see citing works

Antihypertensive drug therapy for mild to moderate hypertension during pregnancy

Abalos, E., Duley, L., & Steyn, D. W. (2014) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd002252.pub3 · Cited by 705 · see citing works

Diabetes as risk factor for incident coronary heart disease in women compared with men: a systematic review and meta-analysis of 64 cohorts including 858,507 individuals and 28,203 coronary events

Peters, S. A. E., Huxley, R. R., & Woodward, M. (2014) · Diabetologia · doi:10.1007/s00125-014-3260-6 · Cited by 701 · see citing works

Follow-up of blood-pressure lowering and glucose control in type 2 diabetes

Zoungas, S., Chalmers, J., Neal, B., Billot, L., Li, Q., Hirakawa, Y., Arima, H., Monaghan, H., Joshi, R., Colagiuri, S., et al. (2014) · New England Journal of Medicine · doi:10.1056/nejmoa1407963 · Cited by 626 · see citing works

Prognostic value of coronary artery calcium screening in subjects with and without diabetes

Raggi, P., Shaw, L. J., Berman, D. S., & Callister, T. Q. (2004) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2003.09.068 · Cited by 608 · see citing works

Efficacy and Safety of Atorvastatin in the Prevention of Cardiovascular End Points in Subjects With Type 2 Diabetes

Knopp, R. H., d’Emden, M., Smilde, J. G., Pocock, S. J., & on behalf of the ASPEN Study Group (2006) · Diabetes Care · doi:10.2337/dc05-2415 · Cited by 550 · see citing works

Effect of Lowering LDL Cholesterol Substantially Below Currently Recommended Levels in Patients With Coronary Heart Disease and Diabetes

Shepherd, J., Barter, P., Carmena, R., Deedwania, P., Fruchart, J.-C., Haffner, S., Hsia, J., Breazna, A., LaRosa, J., Grundy, S., et al. (2006) · Diabetes Care · doi:10.2337/dc05-2465 · Cited by 525 · see citing works

Type 1 Diabetes Mellitus and Cardiovascular Disease

de Ferranti, S. D., de Boer, I. H., Fonseca, V. A., Fox, C. S., Golden, S. H., Lavie, C. J., Magge, S. N., Marx, N., McGuire, D. K., Orchard, T. J., et al. (2014) · Circulation · doi:10.1161/cir.0000000000000034 · Cited by 504 · see citing works

Primary and Secondary Prevention of Cardiovascular Disease

Vandvik, P. O., Lincoff, A. M., Gore, J. M., Gutterman, D. D., Sonnenberg, F. A., Alonso-Coello, P., Akl, E. A., Lansberg, M. G., Guyatt, G. H., & Spencer, F. A. (2012) · Chest · doi:10.1378/chest.11-2306 · Cited by 476 · see citing works

High-Density Lipoprotein as a Therapeutic Target: A Systematic Review

Singh, I. M., Shishehbor, M. H., & Ansell, B. J. (2007) · JAMA · doi:10.1001/jama.298.7.786 · Cited by 468 · see citing works

Pharmacogenetic Study of Statin Therapy and Cholesterol Reduction

Chasman, D. I. (2004) · JAMA · doi:10.1001/jama.291.23.2821 · Cited by 453 · see citing works

Aspirin Dose for the Prevention of Cardiovascular Disease: A Systematic Review

Campbell, C. L., Smyth, S., Montalescot, G., & Steinhubl, S. R. (2007) · JAMA · doi:10.1001/jama.297.18.2018 · Cited by 444 · see citing works

Statin Therapy and Risk of Developing Type 2 Diabetes: A Meta-Analysis

Rajpathak, S. N., Kumbhani, D. J., Crandall, J., Barzilai, N., Alderman, M., & Ridker, P. M. (2009) · Diabetes Care · doi:10.2337/dc09-0738 · Cited by 439 · see citing works

Aspirin for primary prevention of cardiovascular events in people with diabetes: meta-analysis of randomised controlled trials

De Berardis, G., Sacco, M., Strippoli, G. F. M., Pellegrini, F., Graziano, G., Tognoni, G., & Nicolucci, A. (2009) · BMJ · doi:10.1136/bmj.b4531 · Cited by 395 · see citing works

Comparative efficacy and safety of blood pressure-lowering agents in adults with diabetes and kidney disease: a network meta-analysis

Palmer, S. C., Mavridis, D., Navarese, E., Craig, J. C., Tonelli, M., Salanti, G., Wiebe, N., Ruospo, M., Wheeler, D. C., & Strippoli, G. F. M. (2015) · The Lancet · doi:10.1016/s0140-6736(14)62459-4 · Cited by 395 · see citing works

Risk stratification in uncomplicated type 2 diabetes: prospective evaluation of the combined use of coronary artery calcium imaging and selective myocardial perfusion scintigraphy

Anand, D. V., Lim, E., Hopkins, D., Corder, R., Shaw, L. J., Sharp, P., Lipkin, D., & Lahiri, A. (2006) · European Heart Journal · doi:10.1093/eurheartj/ehi808 · Cited by 392 · see citing works

Reduction in Cardiovascular Events With Atorvastatin in 2,532 Patients With Type 2 Diabetes

Sever, P. S., Poulter, N. R., Dahlöf, B., Wedel, H., Collins, R., Beevers, G., Caulfield, M., Kjeldsen, S. E., Kristinsson, A., McInnes, G. T., et al. (2005) · Diabetes Care · doi:10.2337/diacare.28.5.1151 · Cited by 390 · see citing works

Reporting rate of rhabdomyolysis with fenofibrate + statin versus gemfibrozil + any statin

Jones, P. H., & Davidson, M. H. (2005) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2004.08.076 · Cited by 387 · see citing works

Risk of all-cause mortality and vascular events in women versus men with type 1 diabetes: a systematic review and meta-analysis

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Patients with diabetes without significant angiographic coronary artery disease have the same risk of myocardial infarction as patients without diabetes in a real-world population receiving appropriate prophylactic treatment

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Antidiabetic treatment patterns and specialty care utilization among patients with type 2 diabetes and cardiovascular disease

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Diabetes Mellitus Is Associated With Increased Risk of Ischemic Stroke in Patients With and Without Coronary Artery Disease

Olesen, K. K. W., Madsen, M., Gyldenkerne, C., Thrane, P. G., Würtz, M., Thim, T., Jensen, L. O., Eikelboom, J. W., Bøtker, H. E., Sørensen, H. T., et al. (2019) · Stroke · doi:10.1161/strokeaha.119.026099 · Cited by 51 · see citing works

Type 2 diabetes in general practice in Norway 2005–2014: moderate improvements in risk factor control but still major gaps in complication screening

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Cardiovascular, electrophysiologic, and hematologic effects of omega-3 fatty acids beyond reducing hypertriglyceridemia: as it pertains to the recently published REDUCE-IT trial

Sheikh, O., Hei, A. V., Battisha, A., Hammad, T., Pham, S. V., & CHILTON, R. J. (2019) · Cardiovascular Diabetology · doi:10.1186/s12933-019-0887-0 · Cited by 52 · see citing works

Bariatric Surgery in Patients with Cirrhosis and Portal Hypertension

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European Heart Rhythm Association (EHRA) position paper on arrhythmia management and device therapies in endocrine disorders, endorsed by Asia Pacific Heart Rhythm Society (APHRS) and Latin American Heart Rhythm Society (LAHRS)

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Cardiovascular disease prevention strategies for type 2 diabetes mellitus

Katsiki, N., Purrello, F., Tsioufis, C. P., & Mikhailidis, D. P. (2017) · Expert Opinion on Pharmacotherapy · doi:10.1080/14656566.2017.1351946 · Cited by 42 · see citing works

Preclinical carotid atherosclerosis in patients with latent autoimmune diabetes in adults (LADA), type 2 diabetes and classical type 1 diabetes

Hernández, M., López‐Cano, C., Real, J., Valls, J., de Victoria, E. O.-M., Vázquez, F., Rubinat, E., Granado-Casas, M., Alonso, N., Molí, T., et al. (2017) · Cardiovascular Diabetology · doi:10.1186/s12933-017-0576-9 · Cited by 41 · see citing works

Genetic Variants in HSD17B3, SMAD3, and IPO11 Impact Circulating Lipids in Response to Fenofibrate in Individuals With Type 2 Diabetes

Rotroff, D. M., Pijut, S. S., Marvel, S. W., Jack, J. R., Havener, T. M., Pujol, A., Schlüter, A., Graf, G. A., Ginsberg, H. N., Shah, H., et al. (2017) · Clinical Pharmacology & Therapeutics · doi:10.1002/cpt.798 · Cited by 39 · see citing works

Genetic Tools for Coronary Risk Assessment in Type 2 Diabetes: A Cohort Study From the ACCORD Clinical Trial

Morieri, M. L., Gao, H., Pigeyre, M., Shah, H., Sjaarda, J., Mendonça, C., Hastings, T., Buranasupkajorn, P., Motsinger‐Reif, A. A., Rotroff, D. M., et al. (2018) · Diabetes Care · doi:10.2337/dc18-0709 · Cited by 40 · see citing works

Effect of purslane on blood lipids and glucose: A systematic review and meta‐analysis of randomized controlled trials

Hadi, A., Pourmasoumi, M., Najafgholizadeh, A., Kafeshani, M., & Sahebkar, A. (2018) · Phytotherapy Research · doi:10.1002/ptr.6203 · Cited by 39 · see citing works

The healthy Nordic diet for blood glucose control: a systematic review and meta-analysis of randomized controlled clinical trials

Zimorovat, A., Mohammadi, M., Ramezani‐Jolfaie, N., & Salehi‐Abargouei, A. (2019) · Acta Diabetologica · doi:10.1007/s00592-019-01369-8 · Cited by 36 · see citing works

Dyslipidemia and its associated factors among adult diabetes outpatients in West Shewa zone public hospitals, Ethiopia

Abdissa, D., & Hirpa, D. (2022) · BMC Cardiovascular Disorders · doi:10.1186/s12872-022-02489-w · Cited by 36 · see citing works

Reversing the tide — diagnosis and prevention of T2DM in populations of African descent

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Co-occurrence of Cardiometabolic Disease Risk Factors: Unhealthy Eating, Tobacco, Alcohol, Sedentary Lifestyle and Socioeconomic Aspects

Eduard, M.-S., Parra‐Flores, J., & Rodríguez-Fernández, A. (2019) · Arquivos Brasileiros de Cardiologia · doi:10.5935/abc.20190213 · Cited by 35 · see citing works

Relationship Between Number of Multiple Risk Factors and Coronary Artery Disease Risk With and Without Diabetes Mellitus

Yamada, M. H., Fujihara, K., OSAWA, T., Yamamoto, M., Kaneko, M., Kitazawa, M., Matsubayashi, Y., Yamada, T., YAMANAKA, N., Seida, H., et al. (2019) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2019-00168 · Cited by 34 · see citing works

Cardiovascular Complications Over 5 Years and Their Association With Survival in the GERODIAB Cohort of Elderly French Patients With Type 2 Diabetes

Bauduceau, B., Floch, J. P. L., Halimi, S., Verny, C., Doucet, J., & Intergroup, T. S. (2017) · Diabetes Care · doi:10.2337/dc17-1437 · Cited by 33 · see citing works

Comparative effectiveness of angiotensin-converting enzyme inhibitors versus angiotensin II receptor blockers for major renal outcomes in patients with diabetes: a 15-year cohort study

Wu, H.-Y., Peng, C.-L., Chen, P.-C., Chiang, C.-K., Chang, C.-J., Huang, J.-W., Peng, Y.-S., Tu, Y.-K., Chu, T.-S., Hung, K.-Y., et al. (2017) · PLOS ONE · doi:10.1371/journal.pone.0177654 · Cited by 33 · see citing works

The effects of quinoa seed supplementation on cardiovascular risk factors: A systematic review and meta‐analysis of controlled clinical trials

Karimian, J., Abedi, S., Shirinbakhshmasoleh, M., Moodi, F., Moodi, V., & Ghavami, A. (2020) · Phytotherapy Research · doi:10.1002/ptr.6901 · Cited by 33 · see citing works

The effect of polymorphisms (174G> C and 572C> G) on the Interleukin-6 gene in coronary artery disease: a systematic review and meta-analysis

Salari, N., Mansouri, K., Far, A. H., Ghasemi, H., Mohammadi, M., Jalali, R., & Vaisi-Raygani, A. (2021) · Genes and Environment · doi:10.1186/s41021-021-00172-8 · Cited by 31 · see citing works

Pulse wave velocity and cardiac autonomic function in type 2 diabetes mellitus

Chorepsima, S., Eleftheriadou, I., Tentolouris, A., Moyssakis, I. E., Protogerou, A. D., Kokkinos, A. D., Sfikakis, P. P., & Tentolouris, N. (2017) · BMC Endocrine Disorders · doi:10.1186/s12902-017-0178-2 · Cited by 31 · see citing works

The importance of dyslipidaemia in the pathogenesis of cardiovascular disease in people with diabetes

Gonna, H., & Ray, K. K. (2019) · Diabetes Obesity and Metabolism · doi:10.1111/dom.13691 · Cited by 30 · see citing works

Aspirin for Primary Prevention of Cardiovascular Disease in the 21st Century: A Review of the Evidence

Angiolillo, D. J., & Capodanno, D. (2021) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2020.12.022 · Cited by 29 · see citing works

Impact of different dietary approaches on glycemic control and cardiovascular risk factors in patients with type 2 diabetes: a protocol for a systematic review and network meta-analysis

Schwingshackl, L., Chaimani, A., HOFFMANN, G. E., Schwedhelm, C., & Boeing, H. (2017) · Systematic Reviews · doi:10.1186/s13643-017-0455-1 · Cited by 29 · see citing works

A nationwide assessment of blood pressure control and the associated factors in Chinese type 2 diabetes mellitus patients

Zhang, Y., Li, Y., Dong, Y., Wu, Y., Bian, R., Ji-hu, L., & Ji, L. (2019) · Journal of Clinical Hypertension · doi:10.1111/jch.13675 · Cited by 25 · see citing works

Genetic Variation in Kruppel like Factor 15 Is Associated with Left Ventricular Hypertrophy in Patients with Type 2 Diabetes: Discovery and Replication Cohorts

Patel, S. K., Wai, B., Lang, C. C., Levin, D., Palmer, C. N. A., Parry, H., Velkoska, E., Harrap, S. B., Srivastava, P., & Burrell, L. M. (2017) · EBioMedicine · doi:10.1016/j.ebiom.2017.03.036 · Cited by 27 · see citing works

Cardiovascular effects of sodium glucose cotransporter 2 inhibitors

Cavaiola, T. S., & Pettus, J. (2018) · Diabetes Metabolic Syndrome and Obesity · doi:10.2147/dmso.s154602 · Cited by 27 · see citing works

What Should Be the Target Blood Pressure in Elderly Patients With Diabetes?

Solini, A., & Grossman, E. (2016) · Diabetes Care · doi:10.2337/dcs15-3027 · Cited by 27 · see citing works

ApoB/ApoA-I ratio is independently associated with carotid atherosclerosis in type 2 diabetes mellitus with well-controlled LDL cholesterol levels

Jun, J. E., Choi, Y. J., Lee, Y., Kim, D. J., Park, S. W., Huh, B. W., Lee, E. J., Jee, S. H., Hur, K. Y., Choi, S. H., et al. (2017) · The Korean Journal of Internal Medicine · doi:10.3904/kjim.2017.396 · Cited by 26 · see citing works

Cardiovascular Effects of Different GLP-1 Receptor Agonists in Patients with Type 2 Diabetes

Bahtiyar, G., Pujals-Kury, J., & Sacerdote, A. (2018) · Current Diabetes Reports · doi:10.1007/s11892-018-1043-z · Cited by 24 · see citing works

Aspirin for the primary prevention of cardiovascular disease: latest evidence

Capodanno, D., Ingala, S., Calderone, D., & Angiolillo, D. J. (2019) · Expert Review of Cardiovascular Therapy · doi:10.1080/14779072.2019.1651199 · Cited by 24 · see citing works

Inhibition of semicarbazide-sensitive amine oxidase reduces atherosclerosis in apolipoprotein E-deficient mice

Wang, S., Yu, T., Tsai, F., Weston, C. J., Lin, M., Hung, C., Kao, H., Li, Y., Solé, M., Unzeta, M., et al. (2018) · Translational research · doi:10.1016/j.trsl.2018.03.001 · Cited by 24 · see citing works

Impact of pharmacy services on initial clinical outcomes and medication adherence among veterans with uncontrolled diabetes

Gatwood, J. D., Chisholm‐Burns, M. A., Davis, R. L., Thomas, F., Potukuchi, P. K., Hung, A. M., McFarland, M. S., & Kovesdy, C. P. (2018) · BMC Health Services Research · doi:10.1186/s12913-018-3665-x · Cited by 24 · see citing works

Impact of atherosclerotic cardiovascular disease on healthcare resource utilization and costs in patients with type 2 diabetes mellitus in a real-world setting

Weng, W., Tian, Y., Kong, S. X., Ganguly, R., Hersloev, M., Brett, J., & Hobbs, T. M. (2020) · Clinical Diabetes and Endocrinology · doi:10.1186/s40842-019-0090-y · Cited by 24 · see citing works

Validation of the diabetes screening tools proposed by the American Diabetes Association in an aging Chinese population

Woo, Y.-C., Lee, C.-H., Fong, C., Tso, A., Cheung, B., & Lam, K. (2017) · PLoS ONE · doi:10.1371/journal.pone.0184840 · Cited by 19 · see citing works

Influences on Diabetes Self-Management Education Participation in a Low-Income, Spanish-Speaking, Latino Population

Testerman, J., & Chase, D. A. (2017) · Diabetes Spectrum · doi:10.2337/ds16-0046 · Cited by 23 · see citing works

Association between refill adherence to lipid-lowering medications and the risk of cardiovascular disease and mortality in Swedish patients with type 2 diabetes mellitus: a nationwide cohort study

Karlsson, S. A., Hero, C., Svensson, A., Franzén, S., Miftaraj, M., Guðbjörnsdóttir, S., Eeg‐Olofsson, K., Eliasson, B., & Sundell, K. A. (2018) · BMJ Open · doi:10.1136/bmjopen-2017-020309 · Cited by 22 · see citing works

Proprotein convertase subtilisin-kexin type 9 (PCSK9) inhibitors: Shaping the future after the further cardiovascular outcomes research with PCSK9 inhibition in subjects with elevated risk (FOURIER) trial

Katsiki, N., Athyros, V. G., Mikhailidis, D. P., & Mantzoros, C. S. (2017) · Metabolism · doi:10.1016/j.metabol.2017.04.007 · Cited by 21 · see citing works

Factors associated with diabetic nephropathy in children, adolescents, and adults with type 1 diabetes

Huang, C., Ting, W., Lo, F., Tsai, J.-D., Sun, F., Chan, C.-I., Chiang, Y.-T., Lin, C., Cheng, B.-W., Wu, Y., et al. (2017) · Journal of the Formosan Medical Association · doi:10.1016/j.jfma.2017.09.015 · Cited by 22 · see citing works

Cardiovascular Screening for the Asymptomatic Patient with Diabetes: More Cons Than Pros

Makrilakis, K., & Liatis, S. (2017) · Journal of Diabetes Research · doi:10.1155/2017/8927473 · Cited by 21 · see citing works

The Evolving Epidemiology of Atherosclerotic Cardiovascular Disease in People with Diabetes

Pasquel, F. J., Gregg, E. W., & Ali, M. K. (2018) · Endocrinology and Metabolism Clinics of North America · doi:10.1016/j.ecl.2017.11.001 · Cited by 19 · see citing works

Associations between glycaemic control and activation of the renin-angiotensin-aldosterone system in participants with type 2 diabetes mellitus and hypertension

Griffin, T. P., Wall, D., Browne, G. A., Dennedy, M. C., & O’Shea, P. M. (2017) · Annals of Clinical Biochemistry International Journal of Laboratory Medicine · doi:10.1177/0004563217728964 · Cited by 21 · see citing works

Comparison Among Recommendations for the Management of Arterial Hypertension Issued by Last US, Canadian, British and European Guidelines

Antza, C., Doundoulakis, I., Stabouli, S., & Kotsis, V. (2017) · High Blood Pressure & Cardiovascular Prevention · doi:10.1007/s40292-017-0236-x · Cited by 18 · see citing works

Type 2 Diabetes

Samson, S. L., & Garber, A. J. (2018) · Elsevier eBooks · doi:10.1016/b978-0-12-801238-3.95795-7 · Cited by 18 · see citing works

Impact of cardiovascular disease on health care economic burden and resource utilization: a retrospective cohort study in adults in the United States with type 2 diabetes with or without stroke, myocardial infarction, and peripheral arterial disease

King, A., RAJPURA, J. R., Liang, Y. M., Paprocki, Y., & Uzoigwe, C. (2022) · Current Medical Research and Opinion · doi:10.1080/03007995.2022.2125259 · Cited by 18 · see citing works

Intensive versus standard multifactorial cardiovascular risk factor control in screen‐detected type 2 diabetes: 5‐year and longer‐term modelled outcomes of the ADDITION‐Leicester study

Webb, D. R., Dales, J., Zaccardi, F., Hill, S., Moore, C., Farooqi, A. M., Griffin, S. J., Davies, M. J., & Khunti, K. K. (2018) · Diabetes/Metabolism Research and Reviews · doi:10.1002/dmrr.3111 · Cited by 16 · see citing works

Intensive multidisciplinary weight management in patients with type 1 diabetes and obesity: a one-year retrospective matched cohort study

Mottalib, A., Tomah, S., Hafida, S., Elseaidy, T., Kasetty, M., Ashrafzadeh, S., & Hamdy, O. (2019) · Diabetes, Obesity and Metabolism · doi:10.1111/dom.13478 · Cited by 15 · see citing works

Impact of diabetes on subclinical atherosclerosis and major cardiovascular events in individuals with and without non-alcoholic fatty liver disease

Wang, B., Zhao, Z., Liu, S., Wang, S., Chen, Y., Xu, Y. H., Xu, M., Wang, W., Ning, G., Li, M., et al. (2021) · Diabetes Research and Clinical Practice · doi:10.1016/j.diabres.2021.108873 · Cited by 15 · see citing works

Prevalence of nephropathy in Indian children and youth with type 1 diabetes mellitus

Karguppikar, M. B., Oza, C. M., Shah, N., Khadilkar, V. V., Gondhalekar, K. M., & Khadilkar, A. V. (2022) · Journal of Pediatric Endocrinology and Metabolism · doi:10.1515/jpem-2021-0644 · Cited by 15 · see citing works

Association of High Levels of Spot Urine Protein with High Blood Pressure, Mean Arterial Pressure and Pulse Pressure with the Development of Diabetic Chronic Kidney Dysfunction or Failure among Diabetic Patients. Statistical Regression Modeling to Predict Diabetic Proteinuria

Aziz, K. M. A. (2018) · Current Diabetes Reviews · doi:10.2174/1573399814666180924114041 · Cited by 16 · see citing works

Laparoscopic loop duodenaljejunal bypass with sleeve gastrectomy in type 2 diabetic patients

Hanipah, Z. N., Hsin, M.-C., Liu, C.-C., & Huang, C. (2019) · Surgery for Obesity and Related Diseases · doi:10.1016/j.soard.2019.01.016 · Cited by 15 · see citing works

A Mobile Health-Based Disease Management Program Improves Blood Pressure in People With Multiple Lifestyle-Related Diseases at Risk of Developing Vascular Disease ― A Retrospective Observational Study ―

Kanai, M., Toda, T., Yamamoto, K., Akimoto, M., & Hagiwara, Y. (2022) · Circulation Reports · doi:10.1253/circrep.cr-22-0024 · Cited by 14 · see citing works

Evaluating the short-term cost-effectiveness of liraglutide versus lixisenatide in patients with type 2 diabetes in the United States

Hunt, B., McConnachie, C. C., Gamble, C. L., & Dang‐Tan, T. (2017) · Journal of Medical Economics · doi:10.1080/13696998.2017.1347793 · Cited by 14 · see citing works

Dyslipidaemia in the elderly: to treat or not to treat?

Katsiki, N., Kolovou, G. D., Pérez‐Martínez, P., & Mikhailidis, D. P. (2018) · Expert Review of Clinical Pharmacology · doi:10.1080/17512433.2018.1425138 · Cited by 14 · see citing works

Predicting the risk of atherosclerotic cardiovascular disease (ASCVD) in Pakistani population

Hassan, K., Mohydin, B. S., Fawwad, A., Waris, N., Iqbal, S., & Jawaid, M. (2018) · Clinical Epidemiology and Global Health · doi:10.1016/j.cegh.2018.04.002 · Cited by 14 · see citing works

Simultaneous angiotensin receptor blockade and glucagon‐like peptide‐1 receptor activation ameliorate albuminuria in obese insulin‐resistant rats

Rodríguez, R., Escobedo, B., Lee, A. Y., Thorwald, M. A., Godoy-Lugo, J. A., Nakano, D., Nishiyama, A., Parkes, D. G., & Ortiz, R. M. (2019) · Clinical and Experimental Pharmacology and Physiology · doi:10.1111/1440-1681.13206 · Cited by 14 · see citing works

Incidence and Predictors of Aspirin Discontinuation in Older Adult Veteran Nursing Home Residents at End of Life

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Prescription of lipid-lowering medications for patients with type 2 diabetes mellitus and risk-associated LDL cholesterol: a nationwide study of guideline adherence from the Swedish National Diabetes Register

Karlsson, S. A., Franzén, S., Svensson, A., Miftaraj, M., Eliasson, B., & Sundell, K. A. (2018) · BMC Health Services Research · doi:10.1186/s12913-018-3707-4 · Cited by 13 · see citing works

Individual and Combined Cardiometabolic Morbidities and the Subsequent Risk of Cardiovascular Events in Chinese Adults

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Blood Pressure Monitoring as a Digital Health Tool for Improving Diabetes Clinical Outcomes: Retrospective Real-world Study

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8. Cardiovascular Disease and Risk Management

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Section 10: Cardiovascular Disease and Risk Management

(2025) · Clinical Diabetes · doi:10.2337/cd25-a010

Chapter 17: Cardiovascular Disease and Risk Management

(2022) · American Diabetes Association eBooks · doi:10.2337/9781580408172.ch17

Managing Cardiovascular Disease and Events in the Patient with Diabetes

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Topics in Cardiovascular Disease and Diabetes

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