PD-1 Blockade in Tumors with Mismatch-Repair Deficiency
Le, Dung T., Uram, Jennifer N., Wang, Hao, Bartlett, Bjarne R., Kemberling, Holly, Eyring, Aleksandra D., Skora, Andrew D., Luber, Brandon S., Azad, Nilofer S., Laheru, Dan, Biedrzycki, Barbara, Donehower, Ross C., Zaheer, Atif, Fisher, George A., Crocenzi, Todd S., Lee, James J., Duffy, Steven M., Goldberg, Richard M., de la Chapelle, Albert, Koshiji, Minori, Bhaijee, Feriyl, Huebner, Thomas, Hruban, Ralph H., Wood, Laura D., Cuka, Nathan, Pardoll, Drew M., Papadopoulos, Nickolas, Kinzler, Kenneth W., Zhou, Shibin, Cornish, Toby C., Taube, Janis M., Anders, Robert A., Eshleman, James R., Vogelstein, Bert, Diaz, Luis A.·2015·New England Journal of Medicine
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- Genomic correlates of response to immune checkpoint blockadeKeenan, Tanya E., Burke, Kelly P., Van Allen, Eliezer M. · 2019 · Nature Medicine
- Interleukin-17–induced neutrophil extracellular traps mediate resistance to checkpoint blockade in pancreatic cancerYu Zhang, Vidhi Chandra, Erick Marcelo Riquelme, Prasanta Dutta, Pompeyo R. Quesada, Amanda I. Rakoski, Michelle Annabel Zoltan, Nivedita Arora, Seyda Baydogan, William T. Horne et al. · 2020 · The Journal of Experimental Medicine
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- 'Final common pathway' of human cancer immunotherapy: targeting random somatic mutationsTran, Eric, Robbins, Paul F, Rosenberg, Steven A · 2017 · Nature Immunology
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- PD-1 Blockade in Tumors with Mismatch-Repair Deficiency2015 · New England Journal of Medicine
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- Pan-cancer adaptive immune resistance as defined by the Tumor Inflammation Signature (TIS): results from The Cancer Genome Atlas (TCGA)Patrick J. Danaher, Sarah E. Warren, Rongze Olivia. Lu, Josue A. Samayoa, Amy H. Sullivan, Irena Pekker, Brett Wallden, Francesco Maria Marincola, Alessandra Cesano · 2018 · Journal for ImmunoTherapy of Cancer
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- Pembrolizumab in patients with CLL and Richter transformation or with relapsed CLLWei Ding, Betsy R LaPlant, Timothy G. Call, Sameer Ashok Parikh, Jose Francisco Leis, Rong Lucy He, Tait D. Shanafelt, Sutapa Sinha, Jennifer G. Le‐Rademacher, Andrew L. Feldman et al. · 2017 · Blood
- The implications of IDH mutations for cancer development and therapyChristopher J. Pirozzi, Hai Yan · 2021 · Nature Reviews Clinical Oncology
- Predictive biomarkers in PD-1/PD-L1 checkpoint blockade immunotherapyXiangjiao Meng, Zhaoqin Huang, Feifei Teng, Ligang Xing, Jinming Yu · 2015 · Cancer Treatment Reviews
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- Paradigms on Immunotherapy Combinations with ChemotherapyDiego Salas‐Benito, José Luis Perez‐Gracia, Mariano Ponz‐Sarvisé, Maria Esperanza Rodriguez-Ruiz, Iván Martínez‐Forero, Eduardo Castañón Álvarez, José María López-Picazo, Miguel F. Sanmamed, Ignacio Melero · 2021 · Cancer Discovery
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- Mechanisms of Resistance to PD-1 and PD-L1 BlockadeTheodore Scott Nowicki, Siwen Hu‐Lieskovan, Antoni Ribas · 2018 · The Cancer Journal
- Tumor Mutational Burden as a Predictive Biomarker for Response to Immune Checkpoint Inhibitors: A Review of Current EvidenceSamuel Jacob Klempner, David A. Fabrizio, Shalmali Bane, Marcia L. Reinhart, Tim Peoples, Siraj Mahamed Ali, Ethan S. Sokol, Garrett Michael Frampton, Alexa Betzig Schrock, Rachel Anhorn et al. · 2019 · The Oncologist
- Clinical outcomes in metastatic uveal melanoma treated with PD‐1 and PD‐L1 antibodiesAlain Patrick Algazi, Katy K. Tsai, Alexander Noor Shoushtari, Rodrigo Ramella Munhoz, Zeynep Eroglu, Josep Maria Piulats, Patrick Alexander Ott, Douglas Buckner Johnson, Jimmy J. Hwang, ADIL I. DAUD et al. · 2016 · Cancer
- Immune checkpoint inhibitors for the treatment of MSI-H/MMR-D colorectal cancer and a perspective on resistance mechanismsİbrahim Halil Şahin, Mehmet Akce, Olatunji Boladale Alese, Walid Labib Shaib, Gregory B. Lesinski, Bassel F. El‐Rayes, Christina Sing-Ying Wu · 2019 · British Journal of Cancer
- Management of Patients with Advanced Prostate Cancer: Report of the Advanced Prostate Cancer Consensus Conference 2019Silke Gillessen, Gerhardt Attard, Tomasz M. Beer, Himisha Beltran, Anders S Bjartell, Alberto Bossi, Alberto Briganti, Robert Glen Bristow, Kim N. Chi, Noel William Clarke et al. · 2020 · European Urology
- DNA sequencing technologies: 2006–2016Elaine R. Mardis · 2017 · Nature Protocols
- T Cell–Inflamed versus Non-T Cell–Inflamed Tumors: A Conceptual Framework for Cancer Immunotherapy Drug Development and Combination Therapy SelectionJonathan Trujillo, Randy F. Sweis, Riyue Bao, Jason J. Luke · 2018 · Cancer Immunology Research
- Deep learning model for the prediction of microsatellite instability in colorectal cancer: a diagnostic studyYamashita, Rikiya, Long, Jin, Longacre, Teri, Peng, Lan, Berry, Gerald, Martin, Brock, Higgins, John, Rubin, Daniel L, Shen, Jeanne · 2021 · The Lancet Oncology
- From state-of-the-art treatments to novel therapies for advanced-stage pancreatic cancerChris Nevala-Plagemann, Manuel M. Hidalgo, Ignacio Garrido‐Laguna · 2019 · Nature Reviews Clinical Oncology
- TIM-3 regulates CD103+ dendritic cell function and response to chemotherapy in breast cancerde Mingo Pulido, Álvaro, Gardner, Alycia, Hiebler, Shandi, Soliman, Hatem, Rugo, Hope S., Krummel, Matthew F., Coussens, Lisa M., Ruffell, Brian · 2018 · Cancer Cell
- The Integrated Genomic Landscape of Thymic Epithelial TumorsMilan Radovich, Curtis R. Pickering, Ina Felau, Gavin Ha, Hailei Zhang, Heejoon Jo, Katherine A. Hoadley, Pavana Anur, Jiexin Zhang, Michael D. McLellan et al. · 2018 · Cancer Cell
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- Improving radiotherapy in cancer treatment: Promises and challengesHelen H.W. Chen, Macus Tien Kuo · 2017 · Oncotarget
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- Aristolochic acids and their derivatives are widely implicated in liver cancers in Taiwan and throughout AsiaAlvin Wei Tian Ng, Song Ling Poon, Mi Ni Huang, Jing Quan Lim, Arnoud Boot, Willie Yu, Yuka Suzuki, Saranya Thangaraju, Cedric Chuan Young Ng, Patrick B. O. Tan et al. · 2017 · Science Translational Medicine
- Genetic Predictors of Response to Systemic Therapy in Esophagogastric CancerYelena Yuriy Janjigian, Francisco Sánchez-Vega, Philip Jonsson, Walid Khaled Chatila, Jaclyn Frances Hechtman, Geoffrey Yuyat Ku, Jamie Cathleen Riches, Yaelle Tuvy, Ritika Kundra, Nancy Bouvier et al. · 2017 · Cancer Discovery
- Immune activation and response to pembrolizumab in POLE-mutant endometrial cancerJanice M. Mehnert, Anshuman Panda, Judy Zhong, Kim Marie Hirshfield, Sherri Damare, Katherine Lane, Levi O. Sokol, Mark N. Stein, Lorna Rodriguez-Rodriquez, Howard L. Kaufman et al. · 2016 · Journal of Clinical Investigation
- Remodeling of the immune and stromal cell compartment by PD-1 blockade in mismatch repair-deficient colorectal cancerJianxia Li, Cheng Wu, Huabin Hu, Ge Qin, Xueqian Wu, Fan Bai, Jianwei Zhang, Yue Cai, Yan Jiun Huang, Chao Wang et al. · 2023 · Cancer Cell
- A panoply of errors: polymerase proofreading domain mutations in cancerEmily Rayner, Inge C. van Gool, Claire Palles, Stephen E. Kearsey, Tjalling Bosse, Ian P.M. Tomlinson, David N. Church · 2016 · Nature reviews. Cancer
- Reliable Pan-Cancer Microsatellite Instability Assessment by Using Targeted Next-Generation Sequencing DataSumit Middha, Liying Zhang, Khédoudja Nafa, Gowtham Jayakumaran, Donna Wong, Hyunjae Ryan Kim, Justyna Sadowska, Michael F. Berger, Deborah F. DeLair, Jinru Shia et al. · 2017 · JCO Precision Oncology
- Evaluating Mismatch Repair Deficiency in Pancreatic Adenocarcinoma: Challenges and RecommendationsZishuo I. Hu, Jinru Shia, Zsofia Kinga Stadler, Anna M. Varghese, Marinela Capanu, Erin E. Salo‐Mullen, Maeve Aine Lowery, Luis Alberto Diaz, Diana L. Mandelker, Kenneth H. Yu et al. · 2018 · Clinical Cancer Research
- Mechanisms regulating T-cell infiltration and activity in solid tumorsLanitis, E., Dangaj, D., Irving, M., Coukos, G. · 2017 · Annals of Oncology
- Insights Gained from Single-Cell Analysis of Immune Cells in the Tumor MicroenvironmentXianwen Ren, Lei Zhang, Yuanyuan Zhang, Ziyi Li, Nathan O. Siemers, Zemin Zhang · 2021 · Annual Review of Immunology
- Clinical Activity and Safety of the Anti–Programmed Death 1 Monoclonal Antibody Dostarlimab for Patients With Recurrent or Advanced Mismatch Repair–Deficient Endometrial CancerAna Oaknin, Anna V. Tinker, Lucy Gilbert, Vanessa Samouëlian, Cara Amanda Mathews, Jubilee Brown, Maria-Pilar Barretina-Ginesta, Víctor Moreno, Adriano Gravina, Cyril Abdeddaim et al. · 2020 · JAMA Oncology
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- Prospects for gene-engineered T cell immunotherapy for solid cancersChristopher Austin Klebanoff, Steven A. Rosenberg, Nicholas P. Restifo · 2016 · Nature Medicine
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- Prevalence and mutational determinants of high tumor mutation burden in breast cancerRomualdo Barroso‐Sousa, Esha Jain, Ofir Cohen, D. Kim, Jorge E. Buendia-Buendia, Eric P. Winer, NU Lin, Sara M. Tolaney, Nikhil Wagle · 2020 · Annals of Oncology
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- Role of the gut microbiota in anticancer therapy: from molecular mechanisms to clinical applicationsZhao, Lin-Yong, Mei, Jia-Xin, Yu, Gang, Lei, Lei, Zhang, Wei-Han, Liu, Kai, Chen, Xiao-Long, Kołat, Damian, Yang, Kun, Hu, Jian-Kun · 2023 · Signal Transduction and Targeted Therapy
- Adaptive immune resistance at the tumour site: mechanisms and therapeutic opportunitiesTae Kon Kim, Esten N. Vandsemb, Roy S. Herbst, Lieping Chen · 2022 · Nature Reviews Drug Discovery
- Crosstalk Between the MSI Status and Tumor Microenvironment in Colorectal CancerLin, Anqi, Zhang, Jian, Luo, Peng · 2020 · Frontiers in Immunology
- Implications of the tumor immune microenvironment for staging and therapeuticsJanis Marie Taube, Jérôme Galon, Lynette Marie Sholl, Scott J. Rodig, Tricia R. Cottrell, Nicolás A. Giraldo, Alexander Spyridon Baras, Sanjay S. Patel, Robert A. Anders, David L. Rimm et al. · 2017 · Modern Pathology
- Mechanisms of Cancer Resistance to ImmunotherapyRilan Bai, Naifei Chen, Lingyu Li, Nawen Du, Ling Bai, Zheng Lv, Huimin Tian, Jiuwei Cui · 2020 · Frontiers in Oncology
- Genomic Analysis of Immune Cell Infiltrates Across 11 Tumor TypesMichael D. Iglesia, Joel S. Parker, Katherine A. Hoadley, Jonathan Stuart Serody, Charles M. Perou, Benjamin Garrett Vincent · 2016 · JNCI Journal of the National Cancer Institute
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- Real-world application of tumor mutational burden-high (TMB-high) and microsatellite instability (MSI) confirms their utility as immunotherapy biomarkersMatteo Palmeri, Janice M. Mehnert, Ann Willman Silk, Salma K. Jabbour, Shridar Ganesan, Pallvi Popli, Gregory Riedlinger, Ryan D. Stephenson, Alexandre Buckley de Meritens, Aliza Leiser et al. · 2021 · ESMO Open
- Alternative tumour-specific antigensChristof C. Smith, Sara R. Selitsky, Shengjie Chai, Paul M. Armistead, Benjamin Garrett Vincent, Jonathan Stuart Serody · 2019 · Nature reviews. Cancer
- Recent advances in triple negative breast cancer: the immunotherapy eraAntonio Marra, Giulia Viale, Giuseppe Curigliano · 2019 · BMC Medicine
- Practical guidance for mismatch repair-deficiency testing in endometrial cancerEllen Stelloo, Anna Mai Jansen, Elisabeth M. Osse, Remi A. Nout, Carien L. Creutzberg, Dina Ruano, David N. Church, Hans M. Morreau, Vincent T.H.B.M. Smit, Tom van Wezel et al. · 2016 · Annals of Oncology
- Tumour burden and efficacy of immune-checkpoint inhibitorsDall’Olio, Filippo G., Marabelle, Aurélien, Caramella, Caroline, Garcia, Camilo, Aldea, Mihaela, Chaput, Nathalie, Robert, Caroline, Besse, Benjamin · 2022 · Nature Reviews Clinical Oncology
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- Real-time targeted genome profile analysis of pancreatic ductal adenocarcinomas identifies genetic alterations that might be targeted with existing drugs or used as biomarkersSinghi, Aatur D., George, Ben, Greenbowe, Joel R., Chung, Jon, Suh, James, Maitra, Anirban, Klempner, Samuel J., Hendifar, Andrew, Milind, Javle M., Golan, Talia et al. · 2019 · Gastroenterology
- Stromal biology and therapy in pancreatic cancer: ready for clinical translation?Albrecht Neeße, Christian Alexander Bauer, Daniel Öhlund, Matthias Lauth, Malte Buchholz, Patrick Michl, David A. Tuveson, Thomas Mathias Gress · 2018 · Gut
- PD-1/PD-L1 blockade in cancer treatment: perspectives and issuesJunzo Hamanishi, Masaki Mandai, Noriomi Matsumura, Kaoru Abiko, Tsukasa Baba, Ikuo Konishi · 2016 · International Journal of Clinical Oncology
- Prognostic and Predictive Biomarkers in GliomasPaulina Śledzińska, Marek G. Bebyn, Jacek Furtak, Janusz Kowalewski, Marzena Anna Lewandowska · 2021 · International Journal of Molecular Sciences
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- Microsatellite Instability: A Predictive Biomarker for Cancer ImmunotherapyLiisa Chang, Minna Chang, Hanna M. Chang, Fuju Chang · 2017 · Applied immunohistochemistry & molecular morphology
- Integrating Proteomics and Transcriptomics for Systematic Combinatorial Chimeric Antigen Receptor Therapy of AMLFabiana Perna, Samuel Berman, Rajesh Kumar Soni, Jorge Mansilla‐Soto, Justin Eyquem, Mohamad Hamieh, Ronald C. Hendrickson, Cameron Brennan, Michel Sadelain · 2017 · Cancer Cell