Empagliflozin, Cardiovascular Outcomes, and Mortality in Type 2 Diabetes
Zinman, Bernard, Wanner, Christoph, Lachin, John M., Fitchett, David, Bluhmki, Erich, Hantel, Stefan, Mattheus, Michaela, Devins, Theresa +4 more·2015·New England Journal of Medicine
Cited by (12,156)
Items 301–400 of 12,156
- The Lancet Commission to reduce the global burden of sudden cardiac death: a call for multidisciplinary actionÉloi Marijon, Kumar Narayanan, Karen L. Smith, Sérgio Barra, Cristina Basso, Marieke T. Blom, Lia Crotti, André d’Ávila, Rajat Deo, Florence Dumas et al. · 2023 · The Lancet
- 2023 ESC Guidelines for the management of acute coronary syndromesRobert A. Byrne, Xavier Rosselló, John Joseph Coughlan, Emanuele Barbato, Colin Berry, Alaide Chieffo, Marc J. Claeys, Gheorghe‐Andrei Dan, Marc Richard Dweck, Mary Galbraith et al. · 2023 · European Heart Journal Acute Cardiovascular Care
- 2018 ACC Expert Consensus Decision Pathway on Novel Therapies for Cardiovascular Risk Reduction in Patients With Type 2 Diabetes and Atherosclerotic Cardiovascular DiseaseDas, Sandeep R., Everett, Brendan M., Birtcher, Kim K., Brown, Jenifer M., Cefalu, William T., Januzzi, James L., Kalyani, Rita Rastogi, Kosiborod, Mikhail, Magwire, Melissa L., Morris, Pamela B. et al. · 2018 · Journal of the American College of Cardiology
- AGE-RAGE axis blockade in diabetic nephropathy: Current status and future directionsSanajou, Davoud, Ghorbani Haghjo, Amir, Argani, Hassan, Aslani, Somayeh · 2018 · European Journal of Pharmacology
- Heart Failure With Preserved Ejection Fraction and DiabetesMcHugh, Kelly, DeVore, Adam D., Wu, Jingjing, Matsouaka, Roland A., Fonarow, Gregg C., Heidenreich, Paul A., Yancy, Clyde W., Green, Jennifer B., Altman, Natasha, Hernandez, Adrian F. · 2019 · Journal of the American College of Cardiology
- SGLT2 Inhibitors: A Review of Their Antidiabetic and Cardioprotective EffectsTentolouris, Anastasios, Vlachakis, Panayotis, Tzeravini, Evangelia, Eleftheriadou, Ioanna, Tentolouris, Nikolaos · 2019 · International Journal of Environmental Research and Public Health
- A Narrative Review of Chronic Kidney Disease in Clinical Practice: Current Challenges and Future PerspectivesM. Evans, R. D. Lewis, A. Morgan, M. Whyte, W. Hanif, Stephen C. Bain, S. Davies, U. Dashora, Z. Yousef, D. Patel et al. · 2021 · Advances in Therapy
- The evolution of diabetic ketoacidosis: An update of its etiology, pathogenesis and managementEbenezer A. Nyenwe, Abbas E. Kitabchi · 2015 · Metabolism
- SGLT2 Inhibition and cardiovascular events: why did EMPA-REG Outcomes surprise and what were the likely mechanisms?Naveed A. Sattar, James B. McLaren, Søren Lund Kristensen, David Preiss, John J.V. McMurray · 2016 · Diabetologia
- Polypharmacy in the Aging Patient: A Review of Glycemic Control in Older Adults With Type 2 DiabetesLipska, Kasia J., Krumholz, Harlan, Soones, Tacara, Lee, Sei J. · 2016 · JAMA
- Effects of SGLT2 inhibitors on systemic and tissue low-grade inflammation: The potential contribution to diabetes complications and cardiovascular diseaseFabrice Bonnet, André Jacques Scheen · 2018 · Diabetes & Metabolism
- Efficacy of Dapagliflozin on Renal Function and Outcomes in Patients With Heart Failure With Reduced Ejection Fraction: Results of DAPA-HFJhund, Pardeep S., Solomon, Scott D., Docherty, Kieran F., Heerspink, Hiddo J.L., Anand, Inder S., Böhm, Michael, Chopra, Vijay, de Boer, Rudolf A., Desai, Akshay S., Ge, Junbo et al. · 2021 · Circulation
- Trends in drug utilization, glycemic control, and rates of severe hypoglycemia, 2006–2013Lipska, Kasia J., Yao, Xiaoxi, Herrin, Jeph, McCoy, Rozalina G., Ross, Joseph S., Steinman, Michael A., Inzucchi, Silvio E., Gill, Thomas M., Krumholz, Harlan M., Shah, Nilay D. · 2017 · Diabetes Care
- Economic Burden of Cardiovascular Disease in Type 2 Diabetes: A Systematic ReviewThomas Ray Einarson, Annabel Acs, Craig Ludwig, Ulrik Haagen Panton · 2018 · Value in Health
- Dapagliflozin in Myocardial Infarction without Diabetes or Heart FailureStefan Karl James, David Erlinge, Robert F. Storey, Darren K. McGuire, Mark de Belder, Niclas Eriksson, Kasper Andersen, David Austin, Gabriel Arefalk, David Carrick et al. · 2023 · NEJM Evidence
- Clinical management of stable coronary artery disease in patients with type 2 diabetes mellitus: a scientific statement from the American Heart AssociationArnold, Suzanne V., Bhatt, Deepak L., Barsness, Gregory W., Beatty, Alexis L., Deedwania, Prakash C., Inzucchi, Silvio E., Kosiborod, Mikhail, Leiter, Lawrence A., Lipska, Kasia J., Newman, Jonathan D. et al. · 2020 · Circulation
- Neuroprotective effect of SGLT2 inhibitors.Pawlos, Agnieszka, Broncel, Marlena, Woźniak, Ewelina, Gorzelak-Pabiś, Paulina · 2021 · Molecules
- Japan Atherosclerosis Society (JAS) Guidelines for Prevention of Atherosclerotic Cardiovascular Diseases 2022Tomonori Okamura, Kazuhisa Tsukamoto, Hidenori Arai, Yoshio Fujioka, Yasushi Ishigaki, Shinji Koba, Hirotoshi Ohmura, Tetsuo Shoji, Koutaro Yokote, Hiroshi Yoshida et al. · 2023 · Journal of Atherosclerosis and Thrombosis
- 10. Microvascular Complications and Foot Care: Standards of Medical Care in Diabetes—2018American Diabetes Association · 2017 · Diabetes Care
- Current trends in epidemiology of cardiovascular disease and cardiovascular risk management in type 2 diabetesYun, Jae-Seung, Ko, Seung-Hyun · 2021 · Metabolism
- Empagliflozin after Acute Myocardial InfarctionJaved Butler, W. Schuyler Jones, Jacob Allen Udell, Stefan D. Anker, Mark Colquhoun Petrie, Josephine Harrington, Michaela Mattheus, Isabella Zwiener, Offer Amir, Maria Cecilia Bahit et al. · 2024 · New England Journal of Medicine
- American Association of Diabetes Educators 2017Ann M. Carracher, Payal H. Marathe, Kelly L. Close · 2017 · Journal of Diabetes
- Excess Cardiovascular Risk in Women Relative to Men Referred for Coronary Angiography Is Associated With Severely Impaired Coronary Flow Reserve, Not Obstructive DiseaseViviany R. Taqueti, Leslee J. Shaw, Nancy R. Cook, Venkatesh Locharla Murthy, Nishant R. Shah, Courtney R. Foster, Jon Mark Hainer, Ron Blankstein, Sharmila Dorbala, Marcelo F. Di Carli · 2016 · Circulation
- Machine Learning to Predict the Risk of Incident Heart Failure Hospitalization Among Patients With Diabetes: The WATCH-DM Risk ScoreMatthew W. Segar, Muthiah Vaduganathan, Kershaw V. Patel, Darren K. McGuire, Javed Butler, Gregg C. Fonarow, Mujeeb A. Basit, Vaishnavi Kannan, Justin Lee Grodin, Brendan M. Everett et al. · 2019 · Diabetes Care
- Emulating Randomized Clinical Trials With Nonrandomized Real-World Evidence StudiesJessica Myers Franklin, Elisabetta Patorno, Rishi J. Desai, Robert J. Glynn, David Martin, Kenneth Quinto, Ajinkya M Pawar, Lily Gui Bessette, Hemin Lee, Elizabeth M. Garry et al. · 2020 · Circulation
- The SGLT2 inhibitor empagliflozin improves the primary diabetic complications in ZDF ratsSebastian Steven, Matthias Walter Oelze, Alina Hanf, Swenja Kröller‐Schön, Fatemeh Kashani, Siyer Roohani, Philipp Welschof, Maximilian Kopp, Ute Gödtel‐Armbrust, Ning Xia et al. · 2017 · Redox Biology
- Nocturnal Hypertension: New Technology and EvidenceKario, Kazuomi · 2018 · Hypertension
- Consensus statement by the American Association of Clinical Endocrinologists and American College of Endocrinology on the comprehensive type 2 diabetes management algorithm—2019 executive summary.Garber, Alan J., Abrahamson, Martin J., Barzilay, Joshua I., Blonde, Lawrence, Bloomgarden, Zachary T., Bush, Michael A., Dagogo-Jack, Samuel, DeFronzo, Ralph A., Einhorn, Daniel, Fonseca, Vivian A. et al. · 2019 · Endocrine Practice
- Comparative efficacy, safety, and cardiovascular outcomes with once-weekly subcutaneous semaglutide in the treatment of type 2 diabetes: Insights from the SUSTAIN 1–7 trialsAroda, V.R., Ahmann, A., Cariou, B., Chow, F., Davies, M.J., Jódar, E., Mehta, R., Woo, V., Lingvay, I. · 2019 · Diabetes & Metabolism
- Very-Low-Calorie Ketogenic Diet (VLCKD) in the Management of Metabolic Diseases: Systematic Review and Consensus Statement from the Italian Society of Endocrinology (SIE)Caprio, M., Infante, M., Moriconi, E., Armani, A., Fabbri, A., Mantovani, G., Mariani, S., Lubrano, C., Poggiogalle, E., Migliaccio, S. et al. · 2019 · Journal of Endocrinological Investigation
- SGLT2 Inhibitors and Cardiovascular Risk: Lessons Learned From the EMPA-REG OUTCOME StudyMuhammad A Abdul‐Ghani, Stefano Del Prato, ROBERT J. CHILTON, Ralph Anthony DeFronzo · 2016 · Diabetes Care
- Hypertension and diabetes: co-prediction and time trajectoriesV. Tsimihodimos, C. González-Villalpando, J. Meigs, E. Ferrannini · 2018 · HYPERTENSION
- 11. Chronic Kidney Disease and Risk Management:
<i>Standards of Medical Care in Diabetes—2022</i>American Diabetes Association Professional Practice Committee · 2022 · Diabetes Care
- Canagliflozin and Cardiovascular and Renal Outcomes in Type 2 Diabetes Mellitus and Chronic Kidney Disease in Primary and Secondary Cardiovascular Prevention Groups: Results From the Randomized CREDENCE TrialMahaffey, Kenneth W., Jardine, Meg J., Bompoint, Severine, Cannon, Christopher P., Neal, Bruce, Heerspink, Hiddo J.L., Charytan, David M., Edwards, Robert, Agarwal, Rajiv, Bakris, George et al. · 2019 · Circulation
- Empagliflozin, a sodium glucose co-transporter-2 inhibitor, alleviates atrial remodeling and improves mitochondrial function in high-fat diet/streptozotocin-induced diabetic ratsQingmiao Shao, Lei Meng, Sharen Lee, Gary Tse, Mengqi Gong, Zhiwei Zhang, Jichao Zhao, Yungang Zhao, Guangping Li, Tong Liu · 2019 · Cardiovascular Diabetology
- Sodium-Glucose Cotransporter 2 Inhibitors and Risk of Hyperkalemia in People With Type 2 Diabetes: A Meta-Analysis of Individual Participant Data From Randomized, Controlled TrialsBrendon Lange Neuen, Megumi Oshima, Rajiv Agarwal, Clare Gabrielle Arnott, David Z.I. Cherney, Robert Edwards, Anna Maria Langkilde, Kenneth W. Mahaffey, Darren K. McGuire, Bruce Neal et al. · 2022 · Circulation
- 11. Chronic Kidney Disease and Risk Management: Standards of Care in Diabetes—2023Nuha A. ElSayed, Grazia Aleppo, Vanita R. Aroda, Raveendhara R. Bannuru, Florence M. Brown, Dennis Bruemmer, Billy S. Collins, Marisa E. Hilliard, Diana M. Isaacs, Eric L. Johnson et al. · 2022 · Diabetes Care
- Executive summary of the 2020 KDIGO Diabetes Management in CKD Guideline: evidence-based advances in monitoring and treatmentde Boer, Ian H., Caramori, M. Luiza, Chan, Juliana C.N., Heerspink, Hiddo J.L., Hurst, Clint, Khunti, Kamlesh, Liew, Adrian, Michos, Erin D., Navaneethan, Sankar D., Olowu, Wasiu A. et al. · 2020 · Kidney International
- Cardiovascular Effects of New Oral Glucose-Lowering AgentsAndré Jacques Scheen · 2018 · Circulation Research
- Cardiomyopathy in obesity, insulin resistance and diabetesMichinari Nakamura, Junichi Sadoshima · 2019 · The Journal of Physiology
- Evaluation of glomerular hemodynamic function by empagliflozin in diabetic mice using in vivo imagingKidokoro, Kengo, Cherney, David Z.I., Bozovic, Andrea, Nagasu, Hajime, Satoh, Minoru, Kanda, Eiichiro, Sasaki, Tamaki, Kashihara, Naoki · 2019 · Circulation
- The beneficial effects of empagliflozin, an SGLT2 inhibitor, on atherosclerosis in ApoE -/- mice fed a western dietHan, Ji Hye, Oh, Tae Jung, Lee, Ghayoung, Maeng, Hyo Jin, Lee, Dong Hwa, Kim, Kyoung Min, Choi, Sung Hee, Jang, Hak Chul, Lee, Hye Seung, Park, Kyong Soo et al. · 2017 · Diabetologia
- Leptin, cardiovascular diseases and type 2 diabetes mellitusNiki Katsiki, Dimitri P. Mikhailidis, Maciej Banach · 2018 · Acta Pharmacologica Sinica
- Erectile dysfunction and diabetes: A melting pot of circumstances and treatmentsGiuseppe Defeudis, Rossella Mazzilli, Marta Tenuta, Giovanni Rossini, Virginia Zamponi, Soraya Olana, Antongiulio Faggiano, Paolo Pozzilli, Andrea Maria Isidori, Daniele Gianfrilli · 2021 · Diabetes/Metabolism Research and Reviews
- Intention to treat and per protocol analysis in clinical trialsTripepi, Giovanni, Chesnaye, Nicholas C., Dekker, Friedo W., Zoccali, Carmine, Jager, Kitty J. · 2020 · Nephrology
- JAK1/JAK2 inhibition by baricitinib in diabetic kidney disease: results from a Phase 2 randomized controlled clinical trialKatherine R. Tuttle, Frank Chip Brosius, Sharon G. Adler, Matthias Kretzler, Ravindra L. Mehta, James Alan Tumlin, Yoshiya Tanaka, Masakazu Haneda, Jiajun Liu, Maria E. Silk et al. · 2017 · Nephrology Dialysis Transplantation
- 2024 ACC/AHA/AACVPR/APMA/ABC/SCAI/SVM/SVN/SVS/SIR/VESS Guideline for the Management of Lower Extremity Peripheral Artery DiseaseGornik, Heather L., Aronow, Herbert D., Goodney, Philip P., Arya, Shipra, Brewster, Luke Packard, Byrd, Lori, Chandra, Venita, Drachman, Douglas E., Eaves, Jennifer M., Ehrman, Jonathan K. et al. · 2024 · Journal of the American College of Cardiology
- Empagliflozin Effects on Pulmonary Artery Pressure in Patients With Heart FailureMichael E. Nassif, Mohammed Qintar, Sheryl L. Windsor, Rita A. Jermyn, David M. Shavelle, Fengming Tang, Sumant Lamba, Kunjan A. Bhatt, John E. Brush, Andrew B. Civitello et al. · 2021 · Circulation
- Cardiac and Kidney Benefits of Empagliflozin in Heart Failure Across the Spectrum of Kidney FunctionFaiez M. Zannad, João Pedro Ferreira, Stuart Pocock, Cordula Zeller, Stefan D. Anker, Javed Butler, Gerasimos S Filippatos, Sibylle Jenny Hauske, Martina Brueckmann, Egon Pfarr et al. · 2020 · Circulation
- Comparison of Ipragliflozin and Pioglitazone Effects on Nonalcoholic Fatty Liver Disease in Patients With Type 2 Diabetes: A Randomized, 24-Week, Open-Label, Active-Controlled TrialDaisuke Ito, Satoshi Shimizu, Kazuyuki Inoue, Daigo Saito, Morifumi Yanagisawa, Kouichi Inukai, Yuji Akiyama, Yoshihiro Morimoto, Mitsuhiko Noda, Akira Shimada · 2017 · Diabetes Care
- Macrovascular Complications in Patients with Diabetes and PrediabetesDou Huang, Marwan M. Refaat, Kamel Mohammedi, Amin Jayyousi, Jassim M. S. Al Suwaidi, Charbel Abi Khalil · 2017 · BioMed Research International
- SGLT-2 inhibitors and the risk of infections: a systematic review and meta-analysis of randomized controlled trialsRobert Puckrin, Marie‐Philippe Saltiel, Pauline Reynier, Laurent Azoulay, Oriana Hoi Yun Yu, Kristian B. Filion · 2018 · Acta Diabetologica
- Post-transplant diabetes mellitus in patients with solid organ transplantsTrond Geir Jenssen, Anders Hartmann · 2019 · Nature Reviews Endocrinology
- Sodium-Glucose Cotransporter 2 Inhibitors Mechanisms of Action: A ReviewJorge Ignacio Fonseca-Correa, Ricardo Correa‐Rotter · 2021 · Frontiers in Medicine
- 11. Chronic Kidney Disease and Risk Management: Standards of Care in Diabetes—2024Nuha A. ElSayed, Grazia Aleppo, Raveendhara R. Bannuru, Dennis Bruemmer, Billy S. Collins, Laya Ekhlaspour, Marisa E. Hilliard, Eric L. Johnson, Kamlesh K. Khunti, Ildiko Lingvay et al. · 2023 · Diabetes Care
- Effects of SGLT2 inhibitors on UTIs and genital infections in type 2 diabetes mellitus: a systematic review and meta-analysisJiali Liu, Ling Li, Sheyu Li, Pengli Jia, Ke Deng, Wenwen Chen, Xin Sun · 2017 · Scientific Reports
- The next generation of therapeutics for chronic kidney diseaseMatthew Douglas Breyer, Katalin Suszták · 2016 · Nature Reviews Drug Discovery
- Ketoacidosis associated with SGLT2 inhibitor treatment: analysis of FAERS dataBlau, Jenny E., Tella, Sri Harsha, Taylor, Simeon I., Rother, Kristina I. · 2017 · Diabetes/Metabolism Research and Reviews
- Pathophysiology and Treatment of Diabetic Cardiomyopathy and Heart Failure in Patients with Diabetes MellitusKazufumi Nakamura, Toru Miyoshi, Masashi Yoshida, Satoshi Akagi, Yukihiro Saito, Kentaro Ejiri, Naoaki Matsuo, Keishi Ichikawa, Keiichiro Iwasaki, Takanori Naito et al. · 2022 · International Journal of Molecular Sciences
- Leptin-Aldosterone-Neprilysin Axis: Identification of Its Distinctive Role in the Pathogenesis of the Three Phenotypes of Heart Failure in People With ObesityPacker, Milton · 2018 · Circulation
- Sodium–glucose cotransporter type 2 inhibitors for the treatment of type 2 diabetes mellitusAndré Jacques Scheen · 2020 · Nature Reviews Endocrinology
- Carbohydrate-based drugs launched during 2000−2021Xin Cao, Xiaojing Du, Heng Jiao, Quanlin An, Ruoxue Chen, Pengfei Fang, Jing Wang, Biao Yu · 2022 · Acta Pharmaceutica Sinica B
- Dulaglutide as add-on therapy to SGLT2 inhibitors in patients with inadequately controlled type 2 diabetes (AWARD-10): a 24-week, randomised, double-blind, placebo-controlled trialLudvik, Bernhard, Frías, Juan P, Tinahones, Francisco J, Wainstein, Julio, Jiang, Honghua, Robertson, Kenneth E, García-Pérez, Luis-Emilio, Woodward, D Bradley, Milicevic, Zvonko · 2018 · The Lancet Diabetes & Endocrinology
- Activation of Skeletal Muscle AMPK Promotes Glucose Disposal and Glucose Lowering in Non-human Primates and MiceEmily Cokorinos, Jake E. Delmore, Allan R. Reyes, Bina Albuquerque, Rasmus Kjøbsted, Nicolas O. Eskesen, Jean-Luc Tran, Aditi Jatkar, Katherine Cialdea, Ryan M. Esquejo et al. · 2017 · Cell Metabolism
- Gliflozins in the Management of Cardiovascular DiseaseEugene Braunwald M. D · 2022 · New England Journal of Medicine
- Diagnostic approaches for diabetic cardiomyopathyAna Lorenzo-Almorós, José Tuñón, Miguel Orejas, Marcelino Cortés, Jesús Egido, Óscar Lorenzo · 2017 · Cardiovascular Diabetology
- Mitochondrial ROS Formation in the Pathogenesis of Diabetic CardiomyopathyNina Kaludercic, Fabio Di Lisa · 2020 · Frontiers in Cardiovascular Medicine
- 11. Chronic Kidney Disease and Risk Management: Standards of Care in Diabetes—2025American Diabetes Association Professional Practice Committee, ElSayed, Nuha A., McCoy, Rozalina G., Aleppo, Grazia, Balapattabi, Kirthikaa, Beverly, Elizabeth A., Briggs Early, Kathaleen, Bruemmer, Dennis, Echouffo-Tcheugui, Justin B., Ekhlaspour, Laya et al. · 2025 · Diabetes Care
- Anti-inflammatory Agents in the Treatment of Diabetes and Its Vascular ComplicationsRena M. Pollack, Marc Yves Donath, Derek LeRoith, Gil Leibowitz · 2016 · Diabetes Care
- Sodium glucose transporter 2 (SGLT2) inhibition with empagliflozin improves cardiac diastolic function in a female rodent model of diabetesJavad Habibi, Annayya Rao Aroor, James R. Sowers, Guanghong Jia, Melvin Ray Hayden, Mona Garro, Brady J. Barron, Eric Mayoux, R. Scott Rector, Adam T. Whaley‐Connell et al. · 2017 · Cardiovascular Diabetology
- Vascular complications in patients with type 2 diabetes: prevalence and associated factors in 38 countries (the DISCOVER study program)Mikhail Kosiborod, Marília Brito Gomes, Antonio Nicolucci, Stuart Pocock, Wolfgang Rathmann, Marina Vladimirovna Shestakova, Hirotaka Watada, Iichiro Shimomura, Hungta Chen, Javier Cid‐Ruzafa et al. · 2018 · Cardiovascular Diabetology
- A review of GLP‐1 receptor agonists: Evolution and advancement, through the lens of randomised controlled trialsAroda, Vanita R. · 2018 · Diabetes, Obesity and Metabolism
- Effects of canagliflozin versus glimepiride on adipokines and inflammatory biomarkers in type 2 diabetesWilliam Timothy Garvey, Luc Van Gaal, Lawrence A. Leiter, Ujjwala Vijapurkar, James F. List, Robert M Cuddihy, Jimmy Ren, Michael J. Davies · 2018 · Metabolism
- Empagliflozin attenuates cardiac microvascular ischemia/reperfusion through activating the AMPKα1/ULK1/FUNDC1/mitophagy pathwayChen Cai, Zhongzhou Guo, Xing Chang, Ziying Li, Feng Wu, Jing He, Tiantian Cao, Kangrong Wang, Nengxian Shi, Hao Zhou et al. · 2022 · Redox Biology
- Highlights in Heart FailureDaniela Tomasoni, Marianna Adamo, Carlo Lombardi, Marco Metra · 2019 · ESC Heart Failure
- Effects of Icosapent Ethyl on Total Ischemic EventsBhatt, Deepak L., Steg, Ph. Gabriel, Miller, Michael, Brinton, Eliot A., Jacobson, Terry A., Ketchum, Steven B., Doyle, Ralph T., Juliano, Rebecca A., Jiao, Lixia, Granowitz, Craig et al. · 2019 · Journal of the American College of Cardiology
- Diabetic CardiomyopathyStefania Paolillo, Fabio Marsico, Maria Prastaro, Francesco Renga, Luca Esposito, Fabiana De Martino, Pierfrancesco Di Napoli, Immacolata Esposito, Antonio Ambrosio, Monica Ianniruberto et al. · 2019 · Heart Failure Clinics
- Empagliflozin Blunts Worsening Cardiac Dysfunction Associated With Reduced NLRP3 (Nucleotide-Binding Domain-Like Receptor Protein 3) Inflammasome Activation in Heart FailureNikole J. Byrne, Nobutoshi Matsumura, Zaid H. Maayah, Mourad Ferdaoussi, Shingo Takahara, Ahmed M. Darwesh, Jody L. Levasseur, James W.S. Jahng, Dyonne Y. Vos, Nirmal Parajuli et al. · 2020 · Circulation Heart Failure
- Standards of specialized diabetes care. Edited by Dedov I.I., Shestakova M.V., Mayorov A.Yu. 9th editionIvan Ivanovich Dedov, Marina Vladimirovna Shestakova, Alexander Yur'evich Mayorov, Ol'ga Konstantinovna Vikulova, Gagik Radikovich Galstyan, Тамара Леонидовна Кураева, Valentina Aleksandrovna Peterkova, Olga Mikhailovna Smirnova, Elena Georgievna Starostina, Elena Viktorovna Surkova et al. · 2019 · Diabetes Mellitus
- Cardiovascular and Renal Outcomes With Canagliflozin According to Baseline Kidney Function: Data From the CANVAS ProgramNeuen, Brendon L., Ohkuma, Toshiaki, Neal, Bruce, Matthews, David R., de Zeeuw, Dick, Mahaffey, Kenneth W., Fulcher, Greg, Desai, Mehul, Li, Qiang, Deng, Hsiaowei et al. · 2018 · Circulation
- Understanding and overcoming metformin gastrointestinal intoleranceFabrice Bonnet, André Jacques Scheen · 2016 · Diabetes Obesity and Metabolism
- An Overview of the Cardiorenal Protective Mechanisms of SGLT2 InhibitorsTeresa Salvatore, Raffaele Galiero, Alfredo Caturano, Luca Rinaldi, Anna Di Martino, Gaetana Albanese, Jessica Di Salvo, Raffaella Epifani, Raffaele Marfella, Giovanni Docimo et al. · 2022 · International Journal of Molecular Sciences
- Effect of the glucagon-like peptide-1 receptor agonists semaglutide and liraglutide on kidney outcomes in patients with type 2 diabetes: pooled analysis of SUSTAIN 6 and LEADERShaman, Ahmed M., Bain, Stephen C., Bakris, George L., Buse, John B., Idorn, Thomas, Mahaffey, Kenneth W., Mann, Johannes F.E., Nauck, Michael A., Rasmussen, Søren, Rossing, Peter et al. · 2022 · Circulation
- Blood pressure and glycaemic effects of dapagliflozin versus placebo in patients with type 2 diabetes on combination antihypertensive therapy: a randomised, double-blind, placebo-controlled, phase 3 studyMichael A. Weber, Traci A. Mansfield, Valerie A. Cain, Nayyar Iqbal, Shamik J. Parikh, Agata Ptaszynska · 2015 · The Lancet Diabetes & Endocrinology
- Sodium‐Glucose Cotransporter 2 Inhibition for the Prevention of Cardiovascular Events in Patients With Type 2 Diabetes Mellitus: A Systematic Review and Meta‐AnalysisArnott, Clare, Li, Qiang, Kang, Amy, Neuen, Brendon L., Bompoint, Severine, Lam, Carolyn S. P., Rodgers, Anthony, Mahaffey, Kenneth W., Cannon, Christopher P., Perkovic, Vlado et al. · 2020 · Journal of the American Heart Association
- Urinary tract and genital infections in patients with type 2 diabetes treated with sodium‐glucose co‐transporter 2 inhibitors: A meta‐analysis of randomized controlled trialsDandan Li, Tiansheng Wang, Su Shen, Zhenwei Fang, Yue Dong, Huilin Tang · 2016 · Diabetes Obesity and Metabolism
- Mineralocorticoid receptor antagonists in diabetic kidney disease — mechanistic and therapeutic effectsJonatan Barrera‐Chimal, Ixchel Lima‐Posada, George L. Bakris, Frédéric Jaisser · 2021 · Nature Reviews Nephrology
- The SGLT2 inhibitor dapagliflozin reduces liver fat but does not affect tissue insulin sensitivity: a randomized, double-blind, placebo-controlled study with 8-week treatment in type 2 diabetes patientsLatva-Rasku, Aino, Honka, Miikka-Juhani, Kullberg, Joel, Mononen, Nina, Lehtimäki, Terho, Saltevo, Juha, Kirjavainen, Anna K., Saunavaara, Virva, Iozzo, Patricia, Johansson, Lars et al. · 2019 · Diabetes Care
- Increased Hematocrit During Sodium-Glucose Cotransporter 2 Inhibitor Therapy Indicates Recovery of Tubulointerstitial Function in Diabetic KidneysMotoaki Sano, Makoto Takei, Yasuyuki Shiraishi, Yoshihiko Suzuki · 2016 · Journal of Clinical Medicine Research
- ESVM Guideline on peripheral arterial diseaseUlrich Frank, Sigrid Nikol, J. J. F. Belch, Vinko Boc, Marianne Brodmann, P. Carpentier, Ali Chraim, Caitríona Canning, Evangelos P. Dimakakos, Anders Gottsäter et al. · 2019 · VASA
- Twenty-Four-Hour Blood Pressure–Lowering Effect of a Sodium-Glucose Cotransporter 2 Inhibitor in Patients With Diabetes and Uncontrolled Nocturnal Hypertension: Results From the Randomized, Placebo-Controlled SACRA StudyKario, Kazuomi, Okada, Kenta, Kato, Mitsutoshi, Nishizawa, Masafumi, Yoshida, Tetsuro, Asano, Tsuguyoshi, Uchiyama, Kazuaki, Niijima, Yawara, Katsuya, Tomohiro, Urata, Hidenori et al. · 2019 · Circulation
- SGLT2 inhibition via dapagliflozin improves generalized vascular dysfunction and alters the gut microbiota in type 2 diabetic miceLee, Dustin M., Battson, Micah L., Jarrell, Dillon K., Hou, Shuofei, Ecton, Kayl E., Weir, Tiffany L., Gentile, Christopher L. · 2018 · Cardiovascular Diabetology
- Metabolomics in Diabetes and Diabetic Complications: Insights from Epidemiological StudiesJin, Qiao, Ma, Ronald Ching Wan · 2021 · Cells
- Evaluation of the Effects of Sodium–Glucose Co-Transporter 2 Inhibition with Empagliflozin on Morbidity and Mortality in Patients with Chronic Heart Failure and a Preserved Ejection Fraction: Rationale for and Design of the EMPEROR-Preserved TrialStefan D. Anker, Javed Butler, Gerasimos S Filippatos, Waheed Jamal, Afshin Salsali, Janet M. Schnee, Karen A. Kimura, Cordula Zeller, Jyothis Thomas George, Martina Brueckmann et al. · 2019 · European Journal of Heart Failure
- The SGLT2 inhibitor canagliflozin in heart failure: the CHIEF-HF remote, patient-centered randomized trialSpertus, John A., Birmingham, Mary C., Nassif, Michael, Damaraju, C. V., Abbate, Antonio, Butler, Javed, Lanfear, David E., Lingvay, Ildiko, Kosiborod, Mikhail N., Januzzi, James L. · 2022 · Nature Medicine
- Effectiveness of dapagliflozin on vascular endothelial function and glycemic control in patients with early-stage type 2 diabetes mellitus: DEFENCE studyFumika Shigiyama, Naoki Kumashiro, Masahiko Miyagi, Kayoko Ikehara, Eiichiro Kanda, Hiroshi Uchino, Takahisa Hirose · 2017 · Cardiovascular Diabetology
- Hypertension and Heart FailureJeremy A. Slivnick, Brent C. Lampert · 2019 · Heart Failure Clinics
- Pooled analysis of Phase III trials indicate contrasting influences of renal function on blood pressure, body weight, and HbA1c reductions with empagliflozinCherney, David Z.I., Cooper, Mark E., Tikkanen, Ilkka, Pfarr, Egon, Johansen, Odd Erik, Woerle, Hans J., Broedl, Uli C., Lund, Søren S. · 2018 · Kidney International
- Dapagliflozin in patients with cardiometabolic risk factors hospitalised with COVID-19 (DARE-19): A randomised, double-blind, placebo-controlled, phase 3 trialKosiborod, Mikhail N, Esterline, Russell, Furtado, Remo H M, Oscarsson, Jan, Gasparyan, Samvel B, Koch, Gary G, Martinez, Felipe, Mukhtar, Omar, Verma, Subodh, Chopra, Vijay et al. · 2021 · The Lancet Diabetes & Endocrinology
- Renal Protection with SGLT2 Inhibitors: Effects in Acute and Chronic Kidney DiseaseClifford J. Bailey, Caroline Day, Srikanth Bellary · 2022 · Current Diabetes Reports