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Effects of Diet versus Gastric Bypass on Metabolic Function in Diabetes
Open accessAbstract
BACKGROUND: Some studies have suggested that in people with type 2 diabetes, Roux-en-Y gastric bypass has therapeutic effects on metabolic function that are independent of weight loss. METHODS: We evaluated metabolic regulators of glucose homeostasis before and after matched (approximately 18%) weight loss induced by gastric bypass (surgery group) or diet alone (diet group) in 22 patients with obesity and diabetes. The primary outcome was the change in hepatic insulin sensitivity, assessed by infusion of insulin at low rates (stages 1 and 2 of a 3-stage hyperinsulinemic euglycemic pancreatic clamp). Secondary outcomes were changes in muscle insulin sensitivity, beta-cell function, and 24-hour plasma glucose and insulin profiles. RESULTS: Weight loss was associated with increases in mean suppression of glucose production from baseline, by 7.04 μmol per kilogram of fat-free mass per minute (95% confidence interval [CI], 4.74 to 9.33) in the diet group and by 7.02 μmol per kilogram of fat-free mass per minute (95% CI, 3.21 to 10.84) in the surgery group during clamp stage 1, and by 5.39 (95% CI, 2.44 to 8.34) and 5.37 (95% CI, 2.41 to 8.33) μmol per kilogram of fat-free mass per minute in the two groups, respectively, during clamp stage 2; there were no significant differences between the groups. Weight loss was associated with increased insulin-stimulated glucose disposal, from 30.5±15.9 to 61.6±13.0 μmol per kilogram of fat-free mass per minute in the diet group and from 29.4±12.6 to 54.5±10.4 μmol per kilogram of fat-free mass per minute in the surgery group; there was no significant difference between the groups. Weight loss increased beta-cell function (insulin secretion relative to insulin sensitivity) by 1.83 units (95% CI, 1.22 to 2.44) in the diet group and by 1.11 units (95% CI, 0.08 to 2.15) in the surgery group, with no significant difference between the groups, and it decreased the areas under the curve for 24-hour plasma glucose and insulin levels in both groups, with no significant difference between the groups. No major complications occurred in either group. CONCLUSIONS: In this study involving patients with obesity and type 2 diabetes, the metabolic benefits of gastric bypass surgery and diet were similar and were apparently related to weight loss itself, with no evident clinically important effects independent of weight loss. (Funded by the National Institutes of Health and others; ClinicalTrials.gov number, NCT02207777.).
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“Caloric restriction can rapidly reduce steatosis and hepatic insulin resistance [41][42][43].”
From Obesity and MASLD: Is weight loss the (only) key to treat metabolic liver disease? (2024) · cites this paper as [43]
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“In people with type 2 diabetes, weight loss after bariatric surgery elicited no additional differences in hepatic or whole-body insulin sensitivity compared to a control diet with comparable calorie intake, suggesting that the reduction of body fat mass is the major contributing factor to the observed metabolic benefits [43].”
From Obesity and MASLD: Is weight loss the (only) key to treat metabolic liver disease? (2024) · cites this paper as [43]
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“Recent interventions with intensive diet and exercise, newer pharmacological agents (e.g., glucagon-like peptide 1 receptor agonists), or surgical weight loss have led to diabetes remission (86 -92)”
From 2. Diagnosis and Classification of Diabetes: Standards of Care in Diabetes—2024 (2024) · cites this paper as [91]
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Reproducible, interactive, scalable and extensible microbiome data science using QIIME 2
Bolyen, E., Rideout, J. R., Dillon, M. R., Bokulich, N. A., Abnet, C. C., Al-Ghalith, G. A., Alexander, H., Alm, E. J., Arumugam, M., Asnicar, F., et al. (2019) · Nature Biotechnology · doi:10.1038/s41587-019-0209-9 · Cited by 23,742
Self-citationBokulich, N. A., Kaehler, B. D., Rideout, J. R., Dillon, M. R., Bolyen, E. K., Knight, R. D., Huttley, G. A., & Caporaso, J. G. (2018) · Microbiome · doi:10.1186/s40168-018-0470-z · Cited by 6,037
Self-citationMechanisms of Insulin Action and Insulin Resistance
Petersen, M. C., & Shulman, G. I. (2018) · Physiological Reviews · doi:10.1152/physrev.00063.2017 · Cited by 3,028
Weight and Type 2 Diabetes after Bariatric Surgery: Systematic Review and Meta-analysis
Buchwald, H., Estok, R., Fahrbach, K., Banel, D., Jensen, M. D., Pories, W. J., Bantle, J. P., & Sledge, I. (2009) · The American Journal of Medicine · doi:10.1016/j.amjmed.2008.09.041 · Cited by 2,551
Bariatric Surgery versus Intensive Medical Therapy for Diabetes — 3-Year Outcomes
Schauer, P. R., Bhatt, D. L., Kirwan, J. P., Wolski, K., Brethauer, S. A., Navaneethan, S. D., Aminian, A., Pothier, C. E., Kim, E. S. H., Nissen, S. E., et al. (2014) · New England Journal of Medicine · doi:10.1056/nejmoa1401329 · Cited by 1,901
Human gut microbiota in obesity and after gastric bypass
Zhang, H., DiBaise, J. K., Zuccolo, A., Kudrna, D., Braidotti, M., Yu, Y., Parameswaran, P., Crowell, M. D., Wing, R., Rittmann, B. E., et al. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0812600106 · Cited by 1,880
Dixon, J. B., O’Brien, P. E., Playfair, J., Chapman, L., Schachter, L. M., Skinner, S., Proietto, J., Bailey, M., & Anderson, M. (2008) · JAMA · doi:10.1001/jama.299.3.316 · Cited by 1,434
Mingrone, G., Panunzi, S., De Gaetano, A., Guidone, C., Iaconelli, A., Nanni, G., Castagneto, M., Bornstein, S., & Rubino, F. (2015) · The Lancet · doi:10.1016/s0140-6736(15)00075-6 · Cited by 1,220
Differential Adaptation of Human Gut Microbiota to Bariatric Surgery–Induced Weight Loss
Furet, J.-P., Kong, L.-C., Tap, J., Poitou, C., Basdevant, A., Bouillot, J.-L., Mariat, D., Corthier, G., Doré, J., Henegar, C., et al. (2010) · Diabetes · doi:10.2337/db10-0253 · Cited by 1,173
Lim, E. L., Hollingsworth, K. G., Aribisala, B. S., Chen, M. J., Mathers, J. C., & Taylor, R. (2011) · Diabetologia · doi:10.1007/s00125-011-2204-7 · Cited by 1,164
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Nagi, K., & Habib, A. M. (2021) · Cellular Signalling · doi:10.1016/j.cellsig.2021.109976 · Cited by 11
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Schauer, P. R., & Rothberg, A. E. (2024) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/clinem/dgae888 · Cited by 13
Weight versus weight-independent effects of Roux-en-Y gastric bypass on type 2 diabetes
Klein, S., & Seeley, R. J. (2023) · Nature Metabolism · doi:10.1038/s42255-023-00823-w · Cited by 10
Self-citationChang, Y., Hsu, C., Chong, K., Yang, P., Ser, K., Lee, P., Chen, S., Hsuan, C., Lee, Y.-C., Hsu, C., et al. (2023) · Obesity Surgery · doi:10.1007/s11695-023-06656-6 · Cited by 11
Schmid, A., Arians, M., Karrasch, T., Pons‐Kühnemann, J., Schäffler, A., Roderfeld, M., & Roeb, E. (2022) · Journal of Clinical Medicine · doi:10.3390/jcm11071756 · Cited by 12
Seo, E., Kwon, Y., ALRomi, A., Eledreesi, M., & Park, S. S. (2024) · Reviews in Endocrine and Metabolic Disorders · doi:10.1007/s11154-023-09864-8 · Cited by 10
Lannoo, M., Simoens, C., Vangoitsenhoven, R., Gillard, P., D’Hoore, A. J. L., Vadder, M. D., Mertens, A. C., Deleus, E., Steenackers, N., Mathieu, C., et al. (2024) · Scientific Reports · doi:10.1038/s41598-024-59048-w · Cited by 12
Queiroz, S., Gadelha, J. G., Husain, N., & Gutu, C. S. (2025) · Obesity Surgery · doi:10.1007/s11695-025-07858-w · Cited by 12
DNA‐mediated UCP1 overexpression in adipose tissue: A promising anti‐obesity gene therapy
Zhao, Z., Hu, L., Song, B., Wu, Q., Lin, J., Liu, Q., Liu, S., Li, J., Wang, M., Li, J., et al. (2025) · Clinical and Translational Medicine · doi:10.1002/ctm2.70491 · Cited by 9
Juiz-Valiña, P., Cordido, M., Outeiriño-Blanco, E., Pértega-Díaz, S., Urones, P., García-Brao, M. J., Mena, E., Pena-Bello, L., Sangiao‐Alvarellos, S., & Cordido, F. (2021) · Journal of Clinical Medicine · doi:10.3390/jcm10163685 · Cited by 9
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Orioli, L., Canouil, M., Sawadogo, K. A., Ning, L., Deldicque, L., Lause, P., de Barsy, M., Froguel, P., Loumaye, A., Deswysen, Y., et al. (2023) · European Journal of Endocrinology · doi:10.1093/ejendo/lvad122 · Cited by 9
Cogollo, V. J., Rivera, C. E., Valera, R. J., Sarmiento-Cobos, M. F., Montorfano, L. M., Wasser, E., Menzo, E. L., Szomstein, S., & Rosenthal, R. J. (2021) · Surgery for Obesity and Related Diseases · doi:10.1016/j.soard.2021.01.031 · Cited by 9
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Haran, A., Bergel, M., Kleiman, D., Hefetz, L., Israeli, H., Weksler‐Zangen, S., Agranovich, B., Abramovich, I., Schyr, R. B., Gottlieb, E., et al. (2023) · iScience · doi:10.1016/j.isci.2023.107046 · Cited by 10
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van der Kolk, B. W., Pirinen, E., Nicoll, R., Pietiläinen, K. H., & Heinonen, S. (2024) · Trends in Endocrinology and Metabolism · doi:10.1016/j.tem.2024.08.002 · Cited by 8
Orioli, L., Thissen, J.-P., & Loumaye, A. (2025) · Clinical Nutrition · doi:10.1016/j.clnu.2025.106547 · Cited by 9
Chen, M., Surbhi, S., & Bailey, J. E. (2021) · American Journal of Health Promotion · doi:10.1177/08901171211024426 · Cited by 8
Stefater‐Richards, M. A., Panciotti, C., Feldman, H. A., GOURASH, W. F., Shirley, E., Hutchinson, J. N., Golick, L., Park, S. W., Courcoulas, A. P., & Stylopoulos, N. (2022) · Obesity · doi:10.1002/oby.23585 · Cited by 8
Spranger, L., Weiner, J. M., Bredow, J., Zeitz, U., Grittner, U., Boschmann, M., Dickmann, S., Stobäus, N., von Schwartzenberg, R. J., Brachs, M., et al. (2023) · Clinical Nutrition · doi:10.1016/j.clnu.2023.02.020 · Cited by 7
Morissette, A., & Mulvihill, E. E. (2024) · Journal of Pharmacy & Pharmaceutical Sciences · doi:10.3389/jpps.2024.13065 · Cited by 8
Hankir, M. K., Langseder, T., Bankoglu, E. E., Ghoreishi, Y., Dischinger, U., Kurlbaum, M., Kroiß, M., Otto, C., le Roux, C. W., Arora, T., et al. (2020) · iScience · doi:10.1016/j.isci.2020.101777 · Cited by 8
Shah, A. M., PRASAD, M. A., Mark, V., Holst, J. J., & Laferrère, B. (2022) · Diabetes Obesity and Metabolism · doi:10.1111/dom.14793 · Cited by 7
Flynn, C. R., Tamboli, R. A., Antoun, J., Sidani, R. M., Williams, B., Spann, M. D., English, W. J., Welch, E. B., Sundaresan, S., & Abumrad, N. N. (2022) · Diabetes Care · doi:10.2337/dc22-0069 · Cited by 8
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Becerril, S., Cienfuegos, J. A., Rodrı́guez, A., Catalán, V., Ramírez, B., Valentí, V., Moncada, R., Unamuno, X., Gómez‐Ambrosi, J., & Frühbeck, G. (2023) · Journal of Physiology and Biochemistry · doi:10.1007/s13105-023-00993-x · Cited by 7
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Balonov, I., Kurlbaum, M., Koschker, A., Stier, C. K., Faßnacht, M., & Dischinger, U. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24032354 · Cited by 6
Lan, N. S. R., Burns, K. A., Bell, D. A., & Watts, G. F. (2020) · Current Opinion in Endocrinology Diabetes and Obesity · doi:10.1097/med.0000000000000594 · Cited by 6
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Kwok, K. H. M., Andersson, D. P., Rydén, M., & Arner, P. (2021) · International Journal of Obesity · doi:10.1038/s41366-021-00914-2 · Cited by 6
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Choi, D., Kim, S., Woo, J., Lee, H., Kim, H., Jeon, J. S., Noh, H., Han, D. C., Kim, S. H., Cho, H., et al. (2022) · Obesity Facts · doi:10.1159/000521730 · Cited by 6
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Mercado, A., Pham, A. T., Wang, Z. K., Huang, W., Chan, P., Ibrahim, H., Gogineni, H. P., Huang, Y., & Wang, J. (2023) · Frontiers in Pharmacology · doi:10.3389/fphar.2023.1133415 · Cited by 6
Ke, Z., Lu, Z., Fan, L., Zhao, Q., Jiang, X., Hu, Z., Sun, F., He, Z., Tang, Y., Li, Q., et al. (2025) · Gut Microbes · doi:10.1080/19490976.2025.2473519 · Cited by 5
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Fries, C., Haange, S., Rolle-Kampczyk, U. E., Till, A., Lammert, M., Grasser, L., Medawar, E., Dietrich, A., Horstmann, A., von Bergen�, M., et al. (2022) · Metabolites · doi:10.3390/metabo12050417 · Cited by 6
Onishi, Y., Oura, T., & Takeuchi, M. (2024) · Diabetes Therapy · doi:10.1007/s13300-024-01534-5 · Cited by 5
Gupta, M., Kaul, S., Velazquez, G., Bandyopadhyay, D., Fonarow, G. C., Klein, A. L., & Ghosh, R. K. (2021) · American Journal of Cardiovascular Drugs · doi:10.1007/s40256-021-00481-x · Cited by 5
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Bannitz, R. F., Kashyap, S. R., & Patti, M. (2021) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/clinem/dgab694 · Cited by 5
Petersen, M. C., Smith, G. I., Farabi, S. S., Palacios, H. H., Shankaran, M., Hellerstein, M. K., Patterson, B. W., & Klein, S. (2026) · Cell Metabolism · doi:10.1016/j.cmet.2026.07.020 · Cited by 5
Self-citationStentebjerg, L. L., Madsen, L. R., Støving, R. K., Hartmann, B., Holst, J. J., Vinter, C. A., Juhl, C. B., Højlund, K., & Jensen, D. M. (2025) · BMJ Open Diabetes Research & Care · doi:10.1136/bmjdrc-2024-004672 · Cited by 7
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Hartl, L., Elias, J., Prager, G., Reiberger, T., & Unger, L. W. (2021) · World Journal of Gastroenterology · doi:10.3748/wjg.v27.i19.2281 · Cited by 4
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Mittendorfer, B., Patterson, B. W., Magkos, F., Yoshino, M., Bradley, D. P., Eagon, J. C., & Klein, S. (2023) · JCI Insight · doi:10.1172/jci.insight.170307 · Cited by 4
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Singh, H., Bhaskar, R., Ghosh, S., Mishra, P. K., Singh, D. K. K., Sinha, J. K., & Han, S. S. (2025) · Tissue and Cell · doi:10.1016/j.tice.2025.103293 · Cited by 4
Kumar, M., Nigam, V., Kumar, S. S., & Pathak, A. K. (2025) · Journal of Diabetes & Metabolic Disorders · doi:10.1007/s40200-025-01625-5 · Cited by 3
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Flannick, J. A. (2022) · The Lancet Diabetes & Endocrinology · doi:10.1016/s2213-8587(22)00034-1 · Cited by 3
Zhou, X., Ke, Z., Sun, F., Li, F., You, Z., Zhang, J., Gao, Y., Zhu, Z., & Tong, W. (2023) · Obesity Surgery · doi:10.1007/s11695-023-06765-2 · Cited by 3
Cefalu, W. T., Andersen, D. K., Arreaza-Rubín, G., Pin, C. L., Sato, S. M., Verchere, C. B., Woo, M., Rosenblum, N. D., Rosenblum, N. D., Cefalu, W. T., et al. (2021) · Canadian Journal of Diabetes · doi:10.1016/j.jcjd.2021.09.126 · Cited by 3
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Abu‐Gazala, S., Bergel, M., Arad, Y., Hefetz, L., Azulai, S., Baker, A., Haran, A., Israeli, H., Kleiman, D., Samuel, I., et al. (2022) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00416.2021 · Cited by 3
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Storm, A. C., & Dayyeh, B. K. A. (2021) · Gastrointestinal Endoscopy · doi:10.1016/j.gie.2020.11.022 · Cited by 3
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Spranger, L., Bredow, J., Zeitz, U., Grittner, U., Boschmann, M., Dickmann, S., Stobäus, N., von Schwartzenberg, R. J., Spranger, J., & Mai, K. (2021) · medRxiv · doi:10.1101/2021.03.25.21254300 · Cited by 3
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Salehi, M., Peterson, R., Tripathy, D., Pezzica, S., DeFronzo, R. A., & Gastaldelli, A. (2023) · medRxiv · doi:10.1101/2023.03.28.23287755 · Cited by 3
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Li, X., Nian, B., Li, R., Cao, X., Liu, Y., Liu, Y., & Xu, Y.-J. (2024) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2022.2119362 · Cited by 5
López-Delgado, D. S., Narvaez, C. A., Gonzales, N. D. C., Martinez-Galaviz, R., Rivera‐Lozada, O., & Barboza, J. J. (2025) · Journal of Clinical Medicine · doi:10.3390/jcm14238349 · Cited by 2
Bianchi, C., Prato, S. D., Rothberg, A. E., & Nauck, M. A. (2026) · Diabetes Obesity and Metabolism · doi:10.1111/dom.70674 · Cited by 2
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Steffen, R., & Horber, F. (2021) · Annals of Surgery Open · doi:10.1097/as9.0000000000000053 · Cited by 2
Rebello, C. J., Greenway, F. L., Zhang, D., Johnson, W. D., Patterson, E., & Raum, W. J. (2022) · Obesity · doi:10.1002/oby.23384 · Cited by 2
Olbers, T., & Hedberg, S. (2023) · Springer eBooks · doi:10.1007/978-3-030-60596-4_56 · Cited by 2
Godwin, I. U. (2023) · Texila international journal of public health · doi:10.21522/tijph.2013.11.02.art023 · Cited by 2
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Ghusn, W., Salameh, Y., Mosleh, K. A., Shah, M., Storm, A. C., Dayyeh, B. K. A., & Ghanem, O. M. (2024) · Surgical Innovation · doi:10.1177/15533506241273368 · Cited by 2
Wilmington, R., Ardavani, A., Hasan, N. E., Alhindi, Y., Ramzan, I., Anyiam, O., & IDRIS, I. R. (2025) · Obesities · doi:10.3390/obesities5010014 · Cited by 4
Agareva, M. Y., Michurina, S. S., Tomilova, A., Shestakova, E., Voznesenskaya, А. А., Sineokaya, M. S., Zubkova, E., Ratner, E. I., Stafeev, I., Parfyonova, Y., et al. (2025) · BMC Endocrine Disorders · doi:10.1186/s12902-025-01999-w · Cited by 2
Xu, L., Liu, L., Xie, Z., Huang, Z., Li, H., Liu, J., He, X., Deng, W., & Li, Y. (2025) · Journal of Diabetes · doi:10.1111/1753-0407.70135 · Cited by 2
Scherbaum, W. A. (2021) · Der Diabetologe · doi:10.1007/s11428-021-00782-4 · Cited by 2
(2023) · PubMed Central · Cited by 2
Ahima, R. S., & Park, H.-K. (2023) · Springer eBooks · doi:10.1007/978-3-031-40116-9_45 · Cited by 2
Newton, E., Pan, J., & Chung, W. (2022) · Clinical Liver Disease · doi:10.1002/cld.1226 · Cited by 2
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Abdul, M. M. S. (2020) · MOspace Institutional Repository (University of Missouri) · doi:10.32469/10355/81575 · Cited by 2
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Lee, G., Lee, Y. C., Park, M., Kim, S. M., Park, J.-H., & Lee, D. H. (2026) · Diabetes & Metabolism Journal · doi:10.4093/dmj.2025.0120 · Cited by 2
Raja, H., Ebrahim, S., Mamidanna, R., Patel, K., Askari, A., Arhi, C., Munasinghe, A., Rashid, F., Al‐Taan, O., Jambulingam, P. S., et al. (2023) · British Journal of Diabetes · doi:10.15277/bjd.2023.409 · Cited by 1
Azizi, M., Lorthioir, A., & Amar, L. (2023) · Elsevier eBooks · doi:10.1016/b978-0-323-88369-6.00047-5 · Cited by 2
Sun, C., Nguyen, É., Prentki, M., & RABASA-LHORET, R. P. R. (2024) · Diabetes Obesity and Metabolism · doi:10.1111/dom.15688 · Cited by 1
Lowe, A. C., Reijnders, D., Tam, C. S., Redman, L. M., Beyl, R. A., LeBlanc, K. A., Hausmann, M. G., Albaugh, V. L., Greenway, F. L., & Ravussin, É. (2024) · Clinical Obesity · doi:10.1111/cob.12726 · Cited by 1
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Musleh, A. M. (2025) · International Journal of Pharmaceutical and Bio-Medical Science · doi:10.47191/ijpbms/v5-i4-09 · Cited by 1
Anyiam, O., & IDRIS, I. R. (2025) · Expert Review of Endocrinology & Metabolism · doi:10.1080/17446651.2025.2527791 · Cited by 1
Samovski, D., Smith, G. I., Palacios, H. H., Pietka, T., Fuchs, A. G., Patti, G. J., Nawaz, A., Kahn, C. R., & Klein, S. (2025) · Diabetes Care · doi:10.2337/dci25-0101 · Cited by 1
Self-citationYao, T. S., Wu, G., Zeng, Y., Xie, Y., Cui, X., Zhang, Q., Yan, C., Cui, Z., Gong, H., Tianze, X., et al. (2026) · Cell Reports Medicine · doi:10.1016/j.xcrm.2026.102616 · Cited by 1
D’Alessio, D. A., & Campbell, J. E. (2026) · Diabetes Obesity and Metabolism · doi:10.1111/dom.70894 · Cited by 1
Plauth, M. (2023) · Elsevier eBooks · doi:10.1016/b978-0-323-98368-6.00004-5 · Cited by 1
Geronikolou, S., Cokkinos, D., Boschiero, D., Chrousos, G. P., & Albanopoulos, K. (2021) · Advances in experimental medicine and biology · doi:10.1007/978-3-030-78787-5_22 · Cited by 1
Godwin, I. U. (2023) · Texila international journal of public health · doi:10.21522/tijph.2013.11.02.art030 · Cited by 3
Aoyama, K., Nakajima, Y., Meguro, S., & Hayashi, K. (2024) · Diabetology International · doi:10.1007/s13340-024-00744-3 · Cited by 2
Metadata
- Authors
- Yoshino, M., Kayser, B. D., Yoshino, J., Stein, R. I., Reeds, D., Eagon, J. C., Eckhouse, S. R., Watrous, J. D., Jain, M., Knight, R., Schechtman, K., Patterson, B. W., & Klein, S.
- Affiliations
- Washington University in St. Louis (US)
- ORCID
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 2020-08-20
- Volume
- 383
- Issue
- 8
- Pages
- 721-732
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- PMC
- PMC7456610
- OpenAlex
- W3057164079
- Semantic Scholar
- 58b956f40f349fa8a015a5f60e342e5528184ac1
- Cited by
- 246
- References
- 47
- Citations by year
- 2026: 15 · 2025: 29 · 2024: 28 · 2023: 41 · 2022: 59 · 2021: 57 · 2020: 17
- FWCI
- 39.73
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- New England Journal of Medicine (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Digital Commons@Becker (Washington University School of Medicine) (submittedVersion)
- eScholarship (California Digital Library) (submittedVersion)
- Funders
- National Heart, Lung, and Blood Institute (T32HL130357)
- National Institute of Diabetes and Digestive and Kidney Diseases (K01DK116917, P30DK063491, P30DK56341, R01DK101578, T32DK007296, U24DK097153)
- NIH Office of the Director (S10OD020025)
- National Institute of Environmental Health Sciences (P42ES010337, R01ES027595)
- Pershing Square Foundation
- Foundation for Barnes-Jewish Hospital
- Topics
- Health Sciences › Medicine › Surgery › Bariatric Surgery and Outcomes
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Treatment and Management
- Keywords
- type 2 diabetes, Roux-en-Y gastric bypass, bariatric surgery, weight loss, dietary therapy, hepatic insulin sensitivity, skeletal muscle insulin sensitivity, beta-cell function, glucose homeostasis, glucose production, insulin-stimulated glucose disposal, obesity, hyperinsulinemic-euglycemic clamp, insulin secretion
- MeSH terms
- Adult, Blood Glucose, Diabetes Mellitus, Type 2, Female, Humans, Insulin, Insulin Resistance, Male, Middle Aged, Obesity, Prospective Studies, Remission Induction, Glucose Clamp Technique, Gastric Bypass, Weight Loss
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
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