An mRNA Vaccine against SARS-CoV-2 — Preliminary Report
Jackson, Lisa A., Anderson, Evan J., Rouphael, Nadine G., Roberts, Paul C., Makhene, Mamodikoe, Coler, Rhea N., McCullough, Michele P., Chappell, James D., Denison, Mark R., Stevens, Laura J., Pruijssers, Andrea J., McDermott, Adrian, Flach, Britta, Doria-Rose, Nicole A., Corbett, Kizzmekia S., Morabito, Kaitlyn M., O’Dell, Sijy, Schmidt, Stephen D., Swanson, Phillip A., Padilla, Marcelino, Mascola, John R., Neuzil, Kathleen M., Bennett, Hamilton, Sun, Wellington, Peters, Etza, Makowski, Mat, Albert, Jim, Cross, Kaitlyn, Buchanan, Wendy, Pikaart-Tautges, Rhonda, Ledgerwood, Julie E., Graham, Barney S., Beigel, John H.·2020·New England Journal of Medicine
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- mRNA-1273 or mRNA-Omicron boost in vaccinated macaques elicits similar B cell expansion, neutralizing responses, and protection from OmicronMatthew Gagné, Juan I. Moliva, Kathryn E. Foulds, Shayne F. Andrew, Barbara J. Flynn, Anne P. Werner, Danielle A. Wagner, I‐Ting Teng, Bob C. Lin, Christopher A. Moore et al. · 2022 · Cell
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- Suboptimal Response to Coronavirus Disease 2019 Messenger RNA Vaccines in Patients With Hematologic Malignancies: A Need for Vigilance in the Postmasking EraMounzer Agha, Maggie Blake, Charles Chilleo, Alan H. Wells, Ghady Haidar · 2021 · Open Forum Infectious Diseases
- Anionic Lipid Nanoparticles Preferentially Deliver mRNA to the Hepatic Reticuloendothelial SystemPattipeiluhu, Roy, Arias‐Alpizar, Gabriela, Basha, Genc, Chan, Karen Y. T., Bussmann, Jeroen, Sharp, Thomas H., Moradi, Mohammad‐Amin, Sommerdijk, Nico, Harris, Edward N., Cullis, Pieter R. et al. · 2022 · Advanced Materials
- A single dose of self-transcribing and replicating RNA-based SARS-CoV-2 vaccine produces protective adaptive immunity in micede Alwis, Ruklanthi, Gan, Esther S., Chen, Shiwei, Leong, Yan Shan, Tan, Hwee Cheng, Zhang, Summer L., Yau, Clement, Low, Jenny G.H., Kalimuddin, Shirin, Matsuda, Daiki et al. · 2021 · Molecular Therapy
- Decline of Humoral Responses against SARS-CoV-2 Spike in Convalescent IndividualsBeaudoin-Bussières, Guillaume, Laumaea, Annemarie, Anand, Sai Priya, Prévost, Jérémie, Gasser, Romain, Goyette, Guillaume, Medjahed, Halima, Perreault, Josée, Tremblay, Tony, Lewin, Antoine et al. · 2020 · mBio
- Chimeric spike mRNA vaccines protect against Sarbecovirus challenge in miceDavid R. Martinez, Alexandra Schäfer, Sarah R. Leist, Gabriela De la Cruz, Ande West, Elena N. Atochina‐Vasserman, Lisa C. Lindesmith, Norbert Pardi, Robert Parks, Maggie Barr et al. · 2021 · Science
- SARS-CoV-2 antibody-positivity protects against reinfection for at least seven months with 95% efficacy2021
- COVID-19: Unmasking Emerging SARS-CoV-2 Variants, Vaccines and Therapeutic StrategiesRenuka Raman, Krishna J. Patel, Kishu Ranjan · 2021 · Biomolecules
- COVID-19 in people with rheumatic diseases: risks, outcomes, treatment considerationsRebecca Grainger, Alfred H.J. Kim, Richard P. Conway, Jinoos Yazdany, Philip Cameron Robinson · 2022 · Nature Reviews Rheumatology
- Structural basis for broad coronavirus neutralizationMaximilian M. Sauer, M. Alejandra Tortorici, Young‐Jun Park, Alexandra C. Walls, Leah J. Homad, Oliver J. Acton, John E. Bowen, Chunyan Wang, Xiaoli Xiong, Willem de van der Schueren et al. · 2021 · Nature Structural & Molecular Biology
- FDA-authorized mRNA COVID-19 vaccines are effective per real-world evidence synthesized across a multi-state health systemColin Pawlowski, Patrick J. Lenehan, Arjun Puranik, Vineet Agarwal, AJ Venkatakrishnan, Michiel J.M. Niesen, John Charles O’Horo, Abinash Virk, Melanie D. Swift, Andrew D. Badley et al. · 2021 · Med
- Elicitation of broadly protective sarbecovirus immunity by receptor-binding domain nanoparticle vaccinesWalls, Alexandra C., Miranda, Marcos C., Schäfer, Alexandra, Pham, Minh N., Greaney, Allison, Arunachalam, Prabhu S., Navarro, Mary-Jane, Tortorici, M. Alejandra, Rogers, Kenneth, O’Connor, Megan A. et al. · 2021 · Cell
- Vaccine delivery systems toward lymph nodesYingyue Ding, Zhaoting Li, Ana Jaklenec, Quanyin Hu · 2021 · Advanced Drug Delivery Reviews
- T Cell Responses to SARS-CoV-2Alessandro Sette, John Sidney, Shane Crotty · 2023 · Annual Review of Immunology
- Polymer‐Based mRNA Delivery Strategies for Advanced TherapiesWenqian Yang, Lucas Mixich, Eger Boonstra, Horacio Cabral · 2023 · Advanced Healthcare Materials
- Nanotechnology for modern medicine: next step towards clinical translationShrey Sindhwani, Warren C. W. Chan · 2021 · Journal of Internal Medicine
- Modeling of waning immunity after SARS-CoV-2 vaccination and influencing factorsLaura Pérez‐Alós, José Juan Almagro Armenteros, Johannes Roth Madsen, Cecilie Bo Hansen, Ida Jarlhelt, Sebastian Rask Hamm, Line Dam Heftdal, Mia Marie Pries‐Heje, Dina Leth Møller, Kamille Fogh et al. · 2022 · Nature Communications
- Drug combination therapy for emerging viral diseasesZeenat A. Shyr, Yu‐Shan Cheng, Donald C. Lo, Wei Zheng · 2021 · Drug Discovery Today
- Germinal center responses to SARS-CoV-2 mRNA vaccines in healthy and immunocompromised individuals2022
- Targeting Inflammation and Immunosenescence to Improve Vaccine Responses in the ElderlyBranca Isabel Pereira, Xiao‐Ning Xu, Arne N. Akbar · 2020 · Frontiers in Immunology
- Human IgG and IgA responses to COVID-19 mRNA vaccinesJulian Campillo Luna, Adam V. Wisnewski, Carrie A. Redlich · 2021 · PLoS ONE
- Nanovaccines: A game changing approach in the fight against infectious diseasesPriyanka, Mai Abdel Haleem Abusalah, Hitesh Chopra, Abhilasha Sharma, Suhad Asad Mustafa, Om Prakash Choudhary, Manish Kumar Sharma, Manish K. Dhawan, Rajiv Khosla, Aanchal Loshali et al. · 2023 · Biomedicine & Pharmacotherapy
- Nucleic acid drugs: recent progress and future perspectivesXiaoyi Sun, Sarra Setrerrahmane, Chencheng Li, Jialiang Hu, Hanmei Xu · 2024 · Signal Transduction and Targeted Therapy
- Orthogonal Design of Experiments for Optimization of Lipid Nanoparticles for mRNA Engineering of CAR T CellsMargaret M. Billingsley, Alex G. Hamilton, David Mai, Savan K. Patel, Kelsey L. Swingle, Neil C. Sheppard, Carl H. June, Michael J. Mitchell · 2021 · Nano Letters
- Kinetics and correlates of the neutralizing antibody response to SARS-CoV-2 infection in humansVanshylla, Kanika, Di Cristanziano, Veronica, Kleipass, Franziska, Dewald, Felix, Schommers, Philipp, Gieselmann, Lutz, Gruell, Henning, Schlotz, Maike, Ercanoglu, Meryem S., Stumpf, Ricarda et al. · 2021 · Cell Host & Microbe
- A Comprehensive Review of Viral Characteristics, Transmission, Pathophysiology, Immune Response, and Management of SARS-CoV-2 and COVID-19 as a Basis for Controlling the PandemicChris R. Triggle, Devendra Bansal, Hong Ding, Md. Mazharul Islam, Elmoubasher Farag, Hamad Abdel Hadi, Ali A. Sultan · 2021 · Frontiers in Immunology
- Staphylococcus aureus Vaccine Research and Development: The Past, Present and Future, Including Novel Therapeutic StrategiesJonah Clegg, Elisabetta Soldaini, Rachel M. McLoughlin, Stephen F. Rittenhouse, Fábio Bagnoli, Sanjay Kumar Phogat · 2021 · Frontiers in Immunology
- Antibody and T Cell Response to SARS-CoV-2 Messenger RNA BNT162b2 Vaccine in Kidney Transplant Recipients and Hemodialysis PatientsDominique Bertrand, M. Hamzaoui, Véronique Lemee, Julie Lamulle, Mélanie Hanoy, Charlotte Laurent, Ludivine Lebourg, Isabelle Étienne, Mathilde Lemoine, Frank Le Roy et al. · 2021 · Journal of the American Society of Nephrology
- SARS-CoV-2 mRNA vaccines induce broad CD4+ T cell responses that recognize SARS-CoV-2 variants and HCoV-NL63Woldemeskel, Bezawit A., Garliss, Caroline C., Blankson, Joel N. · 2021 · Journal of Clinical Investigation
- In vivo kinetics of SARS-CoV-2 infection and its relationship with a person’s infectiousnessRuian Ke, Carolin Zitzmann, David D. Ho, Ruy Miguel Ribeiro, Alan S. Perelson · 2021 · Proceedings of the National Academy of Sciences
- Non-liver mRNA DeliveryLoughrey, David, Dahlman, James E. · 2022 · Accounts of Chemical Research
- Learning from the past: development of safe and effective COVID-19 vaccinesShan Su, Lanying Du, Shibo Jiang · 2020 · Nature Reviews Microbiology
- Pathogenesis of Multiple Organ Injury in COVID-19 and Potential Therapeutic StrategiesMiquéias Lopes‐Pacheco, Pedro Leme Silva, Fernanda Ferreira Cruz, Denise Battaglini, Chiara Robba, Paolo P. Pelosi, Marcelo Marcos Morales, Celso Caruso Neves, Patrícia R. M. Rocco · 2021 · Frontiers in Physiology
- Neutralizing Antibodies Against SARS-CoV-2 Variants After Infection and VaccinationEdara, Venkata Viswanadh, Hudson, William H., Xie, Xuping, Ahmed, Rafi, Suthar, Mehul S. · 2021 · JAMA
- Bivalent SARS-CoV-2 mRNA vaccines increase breadth of neutralization and protect against the BA.5 Omicron variant in miceScheaffer, Suzanne M., Lee, Diana, Whitener, Bradley, Ying, Baoling, Wu, Kai, Liang, Chieh-Yu, Jani, Hardik, Martin, Philippa, Amato, Nicholas J., Avena, Laura E. et al. · 2023 · Nature Medicine
- SARS-CoV-2 Omicron boosting induces de novo B cell response in humansWafaa B. Alsoussi, Sameer Kumar Malladi, Julian Q. Zhou, Zhuoming Liu, Baoling Ying, Wooseob Kim, Aaron J. Schmitz, Tingting Lei, Stephen C. Horvath, Alexandria J. Sturtz et al. · 2023 · Nature
- A single dose of the SARS-CoV-2 vaccine BNT162b2 elicits Fc-mediated antibody effector functions and T cell responsesAlexandra Tauzin, Manon Nayrac, Mehdi Benlarbi, Shang Yu Gong, Romain Gasser, Guillaume Beaudoin-Bussières, Nathalie Brassard, Annemarie Laumaea, Dani Vézina, Jérémie Prévost et al. · 2021 · Cell Host & Microbe
- Immunity to SARS‐CoV‐2 induced by infection or vaccinationXaquín Castro Dopico, Sebastian Ols, Karin Loré, Gunilla B. Karlsson Hedestam · 2021 · Journal of Internal Medicine
- The known unknowns of T cell immunity to COVID-19Karlsson, Annika C., Humbert, Marion, Buggert, Marcus · 2020 · Science Immunology
- Prediction of lipid nanoparticles for mRNA vaccines by the machine learning algorithmWei Wang, Shuo Feng, Zhuyifan Ye, Hanlu Gao, Jinzhong Lin, Defang Ouyang · 2021 · Acta Pharmaceutica Sinica B
- mRNA cancer vaccines: Advances, trends and challengesQing He, Hua Gao, Dejiang Tan, Heng Zhang, Junzhi Wang · 2022 · Acta Pharmaceutica Sinica B
- Cytokine Storm: The Primary Determinant for the Pathophysiological Evolution of COVID-19 DeteriorationRuirong Chen, Zhien Lan, Jujian Ye, Limin Pang, Yi Liu, Wei Wu, Xiaohuan Qin, Yang Guo, Peidong Zhang · 2021 · Frontiers in Immunology
- Shedding of infectious SARS-CoV-2 despite vaccinationKasen K. Riemersma, Luis A. Haddock, Nancy A. Wilson, Nicholas R. Minor, Jens C. Eickhoff, Brittany Grogan, Amanda Kita-Yarbro, Peter Halfmann, Hannah E. Segaloff, Anna Kocharian et al. · 2022 · PLoS Pathogens
- Inhaled mRNA therapy for treatment of cystic fibrosis: Interim results of a randomized, double‐blind, placebo‐controlled phase 1/2 clinical studySteven Mark Rowe, Jonathan B. Zuckerman, Daniel J. Dorgan, Jorge E. Lascano, Karen McCoy, Manu Jain, Michael S. Schechter, Sherstin T. Lommatzsch, V. Indihar, Noah Lechtzin et al. · 2023 · Journal of Cystic Fibrosis
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- Revealing Public Opinion Towards COVID-19 Vaccines With Twitter Data in the United States: Spatiotemporal PerspectiveTao Hu, Siqin Wang, Wei Ping Luo, Mengxi Zhang, Xiao Huang, Yingwei Yan, Regina Liu, Kelly Ly, Viraj Kacker, Bing She et al. · 2021 · Journal of Medical Internet Research
- Efficacy of the BNT162b2 mRNA COVID-19 vaccine in patients with B-cell non-Hodgkin lymphomaChava Perry, Efrat Luttwak, Roi Balaban, Gabi Shefer, M. Morales, Adi Aharon, Yaara Tabib, Yael Chava Cohen, Noam Benyamini, Ofrat Beyar‐Katz et al. · 2021 · Blood Advances
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