The DOI matches its Crossref record; 18 of the 18 references it cites were found in a registry or an index.
Intravascular Imaging–Guided or Angiography-Guided Complex PCI
Abstract
BACKGROUND: Data regarding clinical outcomes after intravascular imaging-guided percutaneous coronary intervention (PCI) for complex coronary-artery lesions, as compared with outcomes after angiography-guided PCI, are limited. METHODS: In this prospective, multicenter, open-label trial in South Korea, we randomly assigned patients with complex coronary-artery lesions in a 2:1 ratio to undergo either intravascular imaging-guided PCI or angiography-guided PCI. In the intravascular imaging group, the choice between intravascular ultrasonography and optical coherence tomography was at the operators' discretion. The primary end point was a composite of death from cardiac causes, target-vessel-related myocardial infarction, or clinically driven target-vessel revascularization. Safety was also assessed. RESULTS: A total of 1639 patients underwent randomization, with 1092 assigned to undergo intravascular imaging-guided PCI and 547 assigned to undergo angiography-guided PCI. At a median follow-up of 2.1 years (interquartile range, 1.4 to 3.0), a primary end-point event had occurred in 76 patients (cumulative incidence, 7.7%) in the intravascular imaging group and in 60 patients (cumulative incidence, 12.3%) in the angiography group (hazard ratio, 0.64; 95% confidence interval, 0.45 to 0.89; P = 0.008). Death from cardiac causes occurred in 16 patients (cumulative incidence, 1.7%) in the intravascular imaging group and in 17 patients (cumulative incidence, 3.8%) in the angiography group; target-vessel-related myocardial infarction occurred in 38 (cumulative incidence, 3.7%) and 30 (cumulative incidence, 5.6%), respectively; and clinically driven target-vessel revascularization in 32 (cumulative incidence, 3.4%) and 25 (cumulative incidence, 5.5%), respectively. There were no apparent between-group differences in the incidence of procedure-related safety events. CONCLUSIONS: Among patients with complex coronary-artery lesions, intravascular imaging-guided PCI led to a lower risk of a composite of death from cardiac causes, target-vessel-related myocardial infarction, or clinically driven target-vessel revascularization than angiography-guided PCI. (Supported by Abbott Vascular and Boston Scientific; RENOVATE-COMPLEX-PCI ClinicalTrials.gov number, NCT03381872).
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Cites
2018 ESC/EACTS guidelines on myocardial revascularization
Neumann, F.-J., Sousa-Uva, M., Ahlsson, A., Alfonso, F., Banning, A. P., Benedetto, U., Byrne, R. A., Collet, J.-P., Falk, V., Head, S. J., et al. (2019) · European Heart Journal · doi:10.1093/eurheartj/ehy394 · Cited by 7,167
Third Universal Definition of Myocardial Infarction
Thygesen, K., Alpert, J. S., Jaffe, A. S., Simoons, M. L., Chaitman, B. R., & White, H. D. (2012) · Circulation · doi:10.1161/cir.0b013e31826e1058 · Cited by 2,985
Garcia-Garcia, H. M., McFadden, E. P., Farb, A., Mehran, R., Stone, G. W., Spertus, J., Onuma, Y., Morel, M.-A., van Es, G.-A., Zuckerman, B., et al. (2018) · Circulation · doi:10.1161/circulationaha.117.029289 · Cited by 990
Räber, L., Mintz, G. S., Koskinas, K. C., Johnson, T. W., Holm, N. R., Onuma, Y., Radu, M. D., Joner, M., Yu, B., Jia, H., et al. (2018) · European Heart Journal · doi:10.1093/eurheartj/ehy285 · Cited by 770
Ali, Z. A., Maehara, A., Généreux, P., Shlofmitz, R. A., Fabbiocchi, F., Nazif, T. M., Guagliumi, G., Meraj, P. M., Alfonso, F., Samady, H., et al. (2016) · The Lancet · doi:10.1016/s0140-6736(16)31922-5 · Cited by 658
Moussa, I. D., Klein, L. W., Shah, B., Mehran, R., Mack, M. J., Brilakis, E. S., Reilly, J. P., Zoghbi, G., Holper, E., & Stone, G. W. (2013) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2013.08.720 · Cited by 650
Una clasificación simple de las lesiones coronarias en bifurcación
Medina, A., de Lezo, J. S., & Pan, M. (2006) · Revista Española de Cardiología · doi:10.1157/13084649 · Cited by 621
Hong, S.-J., Kim, B.-K., Shin, D.-H., Nam, C.-M., Kim, J.-S., Ko, Y.-G., Choi, D., Kang, T.-S., Kang, W.-C., Her, A.-Y., et al. (2015) · JAMA · doi:10.1001/jama.2015.15454 · Cited by 621
Self-citationBangalore, S., Kumar, S., Fusaro, M., Amoroso, N., Attubato, M. J., Feit, F., Bhatt, D. L., & Slater, J. (2012) · Circulation · doi:10.1161/circulationaha.112.097014 · Cited by 574
Efficacy and Safety of Dual Antiplatelet Therapy After Complex PCI
Giustino, G., Chieffo, A., Palmerini, T., Valgimigli, M., Feres, F., Abizaid, A., Costa, R. A., Hong, M.-K., Kim, B.-K., Jang, Y., et al. (2016) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2016.07.760 · Cited by 454
Cited by
2024 ESC Guidelines for the management of chronic coronary syndromes
Vrints, C., Andreotti, F., Koskinas, K. C., Rossello, X., Adamo, M., Ainslie, J., Banning, A. P., Budaj, A., Buechel, R. R., Chiariello, G. A., et al. (2024) · European Heart Journal · doi:10.1093/eurheartj/ehae177 · Cited by 2,774
Rao, S. V., O’Donoghue, M. L., Ruel, M., Rab, T., Tamis-Holland, J. E., Alexander, J. H., Baber, U., Baker, H., Cohen, M. G., Cruz-Ruiz, M., et al. (2025) · Circulation · doi:10.1161/cir.0000000000001309 · Cited by 625
OCT or Angiography Guidance for PCI in Complex Bifurcation Lesions
Holm, N. R., Andreasen, L. D., Neghabat, O., Laanmets, P., Kumsars, I., Bennett, J., Olsen, N. T., Odenstedt, J., Hoffmann, P., Dens, J., et al. (2023) · New England Journal of Medicine · doi:10.1056/nejmoa2307770 · Cited by 375
Stone, G. W., Christiansen, E. H., Ali, Z. A., Andreasen, L. N., Maehara, A., Ahmad, Y., Landmesser, U., & Holm, N. R. (2024) · The Lancet · doi:10.1016/s0140-6736(23)02454-6 · Cited by 323
Metadata
- Authors
- Lee, J. M., Choi, K. H., Song, Y. B., Lee, J.-Y., Lee, S.-J., Lee, S. Y., Kim, S. M., Yun, K. H., Cho, J. Y., Kim, C. J., Ahn, H.-S., Nam, C.-W., Yoon, H.-J., Park, Y. H., Lee, W. S., Jeong, J.-O., Song, P. S., Doh, J.-H., Jo, S.-H., Yoon, C.-H., Kang, M. G., Koh, J.-S., Lee, K. Y., Lim, Y.-H., Cho, Y.-H., Cho, J.-M., Jang, W. J., Chun, K.-J., Hong, D., Park, T. K., Yang, J. H., Choi, S.-H., Gwon, H.-C., & Hahn, J.-Y.
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 2023-05-04
- Volume
- 388
- Issue
- 18
- Pages
- 1668-1679
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W4323262082
- Cited by
- 572
- References
- 18
- FWCI
- 136.42
- Type
- journal article
- Language
- en
- Open access
- closed
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- Lee, J. M., Choi, K. H., Song, Y. B., Lee, J.-Y., Lee, S.-J., Lee, S. Y., Kim, S. M., Yun, K. H., Cho, J. Y., Kim, C. J., Ahn, H.-S., Nam, C.-W., Yoon, H.-J., Park, Y. H., Lee, W. S., Jeong, J.-O., Song, P. S., Doh, J.-H., Jo, S.-H., . . . Hahn, J.-Y. (2023). Intravascular Imaging–Guided or Angiography-Guided Complex PCI. New England Journal of Medicine. https://doi.org/10.1056/nejmoa2216607
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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