The DOI matches its Crossref record; 16 of the 16 references it cites were found in a registry or an index.
Transcatheter Repair for Patients with Tricuspid Regurgitation
Abstract
BACKGROUND: Severe tricuspid regurgitation is a debilitating condition that is associated with substantial morbidity and often with poor quality of life. Decreasing tricuspid regurgitation may reduce symptoms and improve clinical outcomes in patients with this disease. METHODS: We conducted a prospective randomized trial of percutaneous tricuspid transcatheter edge-to-edge repair (TEER) for severe tricuspid regurgitation. Patients with symptomatic severe tricuspid regurgitation were enrolled at 65 centers in the United States, Canada, and Europe and were randomly assigned in a 1:1 ratio to receive either TEER or medical therapy (control). The primary end point was a hierarchical composite that included death from any cause or tricuspid-valve surgery; hospitalization for heart failure; and an improvement in quality of life as measured with the Kansas City Cardiomyopathy Questionnaire (KCCQ), with an improvement defined as an increase of at least 15 points in the KCCQ score (range, 0 to 100, with higher scores indicating better quality of life) at the 1-year follow-up. The severity of tricuspid regurgitation and safety were also assessed. RESULTS: A total of 350 patients were enrolled; 175 were assigned to each group. The mean age of the patients was 78 years, and 54.9% were women. The results for the primary end point favored the TEER group (win ratio, 1.48; 95% confidence interval, 1.06 to 2.13; P = 0.02). The incidence of death or tricuspid-valve surgery and the rate of hospitalization for heart failure did not appear to differ between the groups. The KCCQ quality-of-life score changed by a mean (±SD) of 12.3±1.8 points in the TEER group, as compared with 0.6±1.8 points in the control group (P<0.001). At 30 days, 87.0% of the patients in the TEER group and 4.8% of those in the control group had tricuspid regurgitation of no greater than moderate severity (P<0.001). TEER was found to be safe; 98.3% of the patients who underwent the procedure were free from major adverse events at 30 days. CONCLUSIONS: Tricuspid TEER was safe for patients with severe tricuspid regurgitation, reduced the severity of tricuspid regurgitation, and was associated with an improvement in quality of life. (Funded by Abbott; TRILUMINATE Pivotal ClinicalTrials.gov number, NCT03904147.).
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Cites
2021 ESC/EACTS Guidelines for the management of valvular heart disease
Vahanian, A., Beyersdorf, F., Praz, F., Milojevic, M., Baldus, S., Bauersachs, J., Capodanno, D., Conradi, L., De Bonis, M., De Paulis, R., et al. (2022) · European Heart Journal · doi:10.1093/eurheartj/ehab395 · Cited by 5,685
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Transcatheter Mitral-Valve Repair in Patients with Heart Failure
Stone, G. W., Lindenfeld, J., Abraham, W. T., Kar, S., Lim, D. S., Mishell, J. M., Whisenant, B., Grayburn, P. A., Rinaldi, M., Kapadia, S. R., et al. (2018) · New England Journal of Medicine · doi:10.1056/nejmoa1806640 · Cited by 3,017
Self-citationImpact of tricuspid regurgitation on long-term survival
Nath, J., Foster, E., & Heidenreich, P. A. (2004) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2003.09.036 · Cited by 1,677
2020 ACC/AHA Guideline for the Management of Patients With Valvular Heart Disease: Executive Summary
Otto, C. M., Nishimura, R. A., Bonow, R. O., Carabello, B. A., Erwin, J. P., Gentile, F., Jneid, H., Krieger, E. V., Mack, M., McLeod, C., et al. (2021) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2020.11.035 · Cited by 1,075
Burden of Tricuspid Regurgitation in Patients Diagnosed in the Community Setting
Topilsky, Y., Maltais, S., Medina Inojosa, J., Oguz, D., Michelena, H., Maalouf, J., Mahoney, D. W., & Enriquez-Sarano, M. (2019) · JACC: Cardiovascular Imaging · doi:10.1016/j.jcmg.2018.06.014 · Cited by 852
National Trends and Outcomes in Isolated Tricuspid Valve Surgery
Zack, C. J., Fender, E. A., Chandrashekar, P., Reddy, Y. N. V., Bennett, C. E., Stulak, J. M., Miller, V. M., & Nishimura, R. A. (2017) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2017.10.039 · Cited by 648
Transcatheter Versus Medical Treatment of Patients With Symptomatic Severe Tricuspid Regurgitation
Taramasso, M., Benfari, G., van der Bijl, P., Alessandrini, H., Attinger-Toller, A., Biasco, L., Lurz, P., Braun, D., Brochet, E., Connelly, K. A., et al. (2019) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2019.09.028 · Cited by 479
Self-citationTranscatheter Edge-to-Edge Repair for Treatment of Tricuspid Regurgitation
Lurz, P., von Bardeleben, R. S., Weber, M., Sitges, M., Sorajja, P., Hausleiter, J., Denti, P., Trochu, J.-N., Nabauer, M., Tang, G. H. L., et al. (2021) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2020.11.038 · Cited by 437
Self-citationNickenig, G., Weber, M., Lurz, P., von Bardeleben, R. S., Sitges, M., Sorajja, P., Hausleiter, J., Denti, P., Trochu, J.-N., Näbauer, M., et al. (2019) · The Lancet · doi:10.1016/s0140-6736(19)32600-5 · Cited by 424
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2024 ESC Guidelines for the management of chronic coronary syndromes
Vrints, C., Andreotti, F., Koskinas, K. C., Rossello, X., Adamo, M., Ainslie, J., Banning, A. P., Budaj, A., Buechel, R. R., Chiariello, G. A., et al. (2024) · European Heart Journal · doi:10.1093/eurheartj/ehae177 · Cited by 2,774
McDonagh, T. A., Metra, M., Adamo, M., Gardner, R. S., Baumbach, A., Böhm, M., Burri, H., Butler, J., Čelutkienė, J., Chioncel, O., et al. (2023) · European Heart Journal · doi:10.1093/eurheartj/ehad195 · Cited by 2,612
Martin, S. S., Aday, A. W., Allen, N. B., Almarzooq, Z. I., Anderson, C. A. M., Arora, P., Avery, C. L., Baker-Smith, C. M., Bansal, N., Beaton, A. Z., et al. (2025) · Circulation · doi:10.1161/cir.0000000000001303 · Cited by 1,080
Authors/Task Force Members:, McDonagh, T. A., Metra, M., Adamo, M., Gardner, R. S., Baumbach, A., Böhm, M., Burri, H., Butler, J., Čelutkienė, J., et al. (2024) · European Journal of Heart Failure · doi:10.1002/ejhf.3024 · Cited by 466
Chronological vs Biological Age in Interventional Cardiology
Damluji, A. A., Nanna, M. G., Rymer, J., Kochar, A., Lowenstern, A., Baron, S. J., Narins, C. R., & Alkhouli, M. (2024) · JACC: Cardiovascular Interventions · doi:10.1016/j.jcin.2024.01.284 · Cited by 53
Metadata
- Authors
- Sorajja, P., Whisenant, B., Hamid, N., Naik, H., Makkar, R., Tadros, P., Price, M. J., Singh, G., Fam, N., Kar, S., Schwartz, J. G., Mehta, S., Bae, R., Sekaran, N., Warner, T., Makar, M., Zorn, G., Spinner, E. M., Trusty, P. M., Benza, R., Jorde, U., McCarthy, P., Thourani, V., Tang, G. H. L., Hahn, R. T., & Adams, D. H.
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 2023-05-18
- Volume
- 388
- Issue
- 20
- Pages
- 1833-1842
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W4323076139
- Cited by
- 930
- References
- 16
- FWCI
- 163.41
- Type
- journal article
- Language
- en
- Open access
- closed
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- Sorajja, P., Whisenant, B., Hamid, N., Naik, H., Makkar, R., Tadros, P., Price, M. J., Singh, G., Fam, N., Kar, S., Schwartz, J. G., Mehta, S., Bae, R., Sekaran, N., Warner, T., Makar, M., Zorn, G., Spinner, E. M., Trusty, P. M., . . . Adams, D. H. (2023). Transcatheter Repair for Patients with Tricuspid Regurgitation. New England Journal of Medicine. https://doi.org/10.1056/nejmoa2300525
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