Trends in Metastatic Breast and Prostate Cancer — Lessons in Cancer Dynamics
Abstract
Interview with Dr. H. Gilbert Welch on trends in the incidence of metastatic cancers and their implications for both screening and our understanding of cancer. (06:57)Download Discordant trends in the incidence of metastatic breast and prostate cancer since the widespread implementation of early-detection efforts may reflect distinct disease dynamics or may result from the different screening strategies used.
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Overdiagnosis-related harms may require many years before they become apparent, similar to other cancers.
“This is a difficult balance to achieve since the harms of overdiagnosis can take many years to become evident, as is the case for other cancers.114–116”
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Conte, B., Soldato, D., Razeti, M. G., Fregatti, P., de Azambuja, E., Schettini, F., Prat, A., Mastro, L. D., & Lambertini, M. (2021) · Clinical Breast Cancer · doi:10.1016/j.clbc.2021.10.001 · Cited by 11 · see citing works
Goodson, J. D. (2016) · CHEST Journal · doi:10.1016/j.chest.2016.11.057 · Cited by 11 · see citing works
The Breast Cancer Screening “Arcade” and the “Whack-A-Mole” Efforts to Reduce Access to Screening
Kopans, D. B. (2017) · Seminars in Ultrasound CT and MRI · doi:10.1053/j.sult.2017.06.002 · Cited by 11 · see citing works
Hewitt, K. C., Son, J. D., Glencer, A., Borowsky, A. D., Cooperberg, M. R., & Esserman, L. J. (2020) · Cancer Epidemiology Biomarkers & Prevention · doi:10.1158/1055-9965.epi-20-0110 · Cited by 11 · see citing works
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Moschovas, M. C., Abdel, J., Saikali, S., Sandri, M. F., Bhat, S., Rogers, T., Gamal, A., Loy, D., Patel, E., Reddy, S. K., et al. (2024) · International braz j urol · doi:10.1590/s1677-5538.ibju.2023.0530 · Cited by 10 · see citing works
What's new in screening in 2015?
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Trends in Metastatic Breast and Prostate Cancer.
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Self-citationWho and when should we screen for prostate cancer? Interviews with key opinion leaders
Carlsson, S., Leapman, M. S., Carroll, P. R., Schröder, F. H., Albertsen, P. C., Ilić, D., Barry, M. J., Frosch, D. L., & Vickers, A. J. (2015) · BMC Medicine · doi:10.1186/s12916-015-0526-x · Cited by 9 · see citing works
Self-citationNew agents for the management of resistant metastatic breast cancer
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- Authors
- Welch, H. G., Gorski, D. H., & Albertsen, P. C.
- Affiliations
- Dartmouth Institute for Health Policy and Clinical Practice (US)
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 2015-10-29
- Volume
- 373
- Issue
- 18
- Pages
- 1685-1687
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W2288757641
- Cited by
- 188
- References
- 5
- Citations by year
- 2026: 3 · 2025: 5 · 2024: 7 · 2023: 13 · 2022: 15 · 2021: 11 · 2020: 18 · 2019: 18 · 2018: 19 · 2017: 39 · 2016: 37 · 2015: 2
- FWCI
- 14.13
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- New England Journal of Medicine (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Oncology › Global Cancer Incidence and Screening
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Prostate Cancer Diagnosis and Treatment
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Lung Cancer Diagnosis and Treatment
- Keywords
- metastatic breast cancer, metastatic prostate cancer, cancer incidence trends, cancer screening, early detection, disease dynamics
- MeSH terms
- Adult, Breast Neoplasms, Female, Humans, Male, Mammography, Middle Aged, Neoplasm Metastasis, Prostatic Neoplasms, United States, Incidence, Prostate-Specific Antigen, SEER Program, Early Detection of Cancer
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
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