Vertebrobasilar disease
Abstract
About 20 percent of ischemic strokes involve the posterior circulation. The correct diagnosis is often delayed, and workups in patients with symptoms may not always suggest vertebrobasilar disease. This review explains the causes, typical presentations, and characteristic findings of common strokes resulting from disease in the vertebral, basilar, or posterior cerebral arteries. Recommendations are made for treatment with thrombolytic agents and the prophylactic use of antiplatelet agents or anticoagulants.
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Fewer than 1% of patients with vertebrobasilar ischaemia present with a single presenting symptom.
“Fewer than 1% of patients with vertebrobasilar ischaemia present with a single presenting symptom.”
From 2018 ESC Guidelines for the diagnosis and management of syncope (2018) · cites this paper as [425]
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- Authors
- Savitz, S. I., & Caplan, L. R.
- Affiliations
- Beth Israel Deaconess Medical Center (US)
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 2005-06-23
- Volume
- 352
- Issue
- 25
- Pages
- 2618-2626
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W2615504795
- Cited by
- 485
- References
- 52
- Citations by year
- 2026: 22 · 2025: 16 · 2024: 14 · 2023: 24 · 2022: 33 · 2021: 31 · 2020: 27 · 2019: 30 · 2018: 29 · 2017: 25 · 2016: 14 · 2015: 22 · 2014: 23 · 2013: 21 · 2012: 24
- FWCI
- 2.18
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- New England Journal of Medicine (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Epidemiology › Acute Ischemic Stroke Management
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Cerebrovascular and Carotid Artery Diseases
- Life Sciences › Neuroscience › Neurology › Vestibular and auditory disorders
- Keywords
- vertebrobasilar disease, posterior circulation stroke, ischemic stroke, vertebral artery, basilar artery, posterior cerebral artery, stroke diagnosis, thrombolysis, antiplatelet agents, anticoagulants, stroke prevention
- MeSH terms
- Arteriosclerosis, Brain Ischemia, Consciousness Disorders, Diagnosis, Differential, Embolism, Humans, Prognosis, Vertebrobasilar Insufficiency, Vertigo, Vertebral Artery Dissection
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