The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
The mouse kinome: Discovery and comparative genomics of all mouse protein kinases
Open accessAbstract
We have determined the full protein kinase (PK) complement (kinome) of mouse. This set of 540 genes includes many novel kinases and corrections or extensions to >150 published sequences. The mouse has orthologs for 510 of the 518 human PKs. Nonorthologous kinases arise only by retrotransposition and gene decay. Orthologous kinase pairs vary in sequence conservation along their length, creating a map of functionally important regions for every kinase pair. Many species-specific sequence inserts exist and are frequently alternatively spliced, allowing for the creation of evolutionary lineage-specific functions. Ninety-seven kinase pseudogenes were found, all distinct from the 107 human kinase pseudogenes. Chromosomal mapping links 163 kinases to mutant phenotypes and unlocks the use of mouse genetics to determine functions of orthologous human kinases.
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Cites
The sequence of the human genome
Venter, J. C., Adams, M. D., Myers, E. W., Li, P. W., Mural, R. J., Sutton, G. G., Smith, H. O., Yandell, M., Evans, C. A., Holt, R. A., et al. (2001) · Science · doi:10.1126/science.1058040 · Cited by 13,909
Initial sequencing and comparative analysis of the mouse genome
Mouse Genome Sequencing Consortium (2002) · Nature · doi:10.1038/nature01262 · Cited by 7,187
A molecular timescale for vertebrate evolution
Kumar, S., & Hedges, S. B. (1998) · Nature · doi:10.1038/31927 · Cited by 1,936
Cited by
Mechanisms of specificity in protein phosphorylation
Ubersax, J. A., & Ferrell Jr, J. E. (2007) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2203 · Cited by 1,451
MAPKAP kinases — MKs — two's company, three's a crowd
Gaestel, M. (2006) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm1834 · Cited by 413
OrthoInspector: comprehensive orthology analysis and visual exploration
Linard, B., Thompson, J. D., Poch, O., & Lecompte, O. (2011) · BMC Bioinformatics · doi:10.1186/1471-2105-12-11 · Cited by 64
Zhong, W., Xie, Y., Abdallah, M., Awonuga, A. O., Slater, J. A., Sipahi, L., Puscheck, E. E., & Rappolee, D. A. (2010) · Reproduction · doi:10.1530/rep-10-0268 · Cited by 48
MacKay, K. B., Tu, Y., Young, S. G., & Clarke, S. G. (2013) · PLoS ONE · doi:10.1371/journal.pone.0065967 · Cited by 14
Metadata
- Authors
- Caenepeel, S., Charydczak, G., Sudarsanam, S., Hunter, T., & Manning, G.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 2004-08-02
- Volume
- 101
- Issue
- 32
- Pages
- 11707-11712
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W2113071946
- Cited by
- 308
- References
- 3
- FWCI
- 7.33
- Type
- journal article
- Language
- en
- Open access
- green
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- Caenepeel, S., Charydczak, G., Sudarsanam, S., Hunter, T., & Manning, G. (2004). The mouse kinome: Discovery and comparative genomics of all mouse protein kinases. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.0306880101
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