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Cited by 315

The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.

Humanized anti-CD25 (daclizumab) inhibits disease activity in multiple sclerosis patients failing to respond to interferon β

Open access
Bielekova, Bibiana, Richert, Nancy, Howard, Thomas, Blevins, Gregg, Markovic-Plese, Silva, McCartin, Jennifer, Würfel, Jens, Ohayon, Joan, Waldmann, Thomas A., McFarland, Henry F., Martin, Roland·2004·Proceedings of the National Academy of Sciences
DOI 10.1073/pnas.0402653101
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Abstract

Identifying effective treatment combinations for MS patients failing standard therapy is an important goal. We report the results of a phase II open label baseline-to-treatment trial of a humanized monoclonal antibody against CD25 (daclizumab) in 10 multiple sclerosis patients with incomplete response to IFN-β therapy and high brain inflammatory and clinical disease activity. Daclizumab was very well tolerated and led to a 78% reduction in new contrast-enhancing lesions and to a significant improvement in several clinical outcome measures.

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Crossref · 10.1073/pnas.0402653101

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Metadata

Authors
Bielekova, B., Richert, N., Howard, T., Blevins, G., Markovic-Plese, S., McCartin, J., Würfel, J., Ohayon, J., Waldmann, T. A., McFarland, H. F., & Martin, R.
Venue
Proceedings of the National Academy of Sciences
Publisher
Proceedings of the National Academy of Sciences
Published
2004-05-25
Volume
101
Issue
23
Pages
8705-8708
ISSN
  • 0027-8424 (ISSN-L)
  • 1091-6490
DOI
10.1073/pnas.0402653101
OpenAlex
W1996481500
Cited by
315
References
1
FWCI
14.79
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Humanized anti-CD25 (daclizumab) inhibits disease activity in multiple sclerosis patients failing to respond to interferon β. https://app.cochat.ai/papers/10.1073/pnas.0402653101
The paper
Bielekova, B., Richert, N., Howard, T., Blevins, G., Markovic-Plese, S., McCartin, J., Würfel, J., Ohayon, J., Waldmann, T. A., McFarland, H. F., & Martin, R. (2004). Humanized anti-CD25 (daclizumab) inhibits disease activity in multiple sclerosis patients failing to respond to interferon β. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.0402653101

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.