The DOI matches its Crossref record; 31 of the 31 references it cites were found in a registry or an index.
Social interaction-mediated lifespan extension of Drosophila Cu/Zn superoxide dismutase mutants
Open accessAbstract
Beneficial effects of social interaction on aging have been studied in humans and other species. We found that short-lived Drosophila mutants of the antioxidant enzyme Cu/Zn superoxide dismutase displayed a robust lifespan extension, with improved stress resistance and motor ability, upon cohousing with active flies of longer lifespan or younger age. Genetic, surgical, and environmental manipulations revealed motor and sensory components in behavioral interactions required for the lifespan extension induced by cohousing. Our results provide a definitive case of beneficial social interaction on lifespan and a useful entry point for analyzing the underlying molecular networks and physiological mechanisms.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“social isolation decreases the lifespan of the fruit fly, Drosophila melanogaster;12”
From Social isolation (2011) · cites this paper as [12]
In the citing paper
“experimental studies in nonhuman social species indicate that isolation has direct, deleterious physiological effects.”
From Social isolation (2011) · cites this paper as [12]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Genetic variations of Drosophila melanogaster.
Lindsley, D. L., & Grell, E. H. (1968) · Biodiversity Heritage Library (Smithsonian Institution) · doi:10.5281/zenodo.10755360 · Cited by 2,623
The influence of social hierarchy on primate health
Sapolsky, R. M. (2005) · Science · doi:10.1126/science.1106477 · Cited by 2,113
Extension of Life-Span by Loss of CHICO, a Drosophila Insulin Receptor Substrate Protein
Clancy, D. J., Gems, D., Harshman, L. G., Oldham, S., Stocker, H., Hafen, E., Leevers, S. J., & Partridge, L. (2001) · Science · doi:10.1126/science.1057991 · Cited by 1,436
Uvnäs-Moberg, K. (1998) · Psychoneuroendocrinology · doi:10.1016/s0306-4530(98)00056-0 · Cited by 966 · cited 1×
“However, the underlying molecular networks require further exploration (6).”
BackgroundHall, J. C. (1994) · Science · doi:10.1126/science.8209251 · Cited by 668
High-quality life extension by the enzyme peptide methionine sulfoxide reductase
Ruan, H., Tang, X. D., Chen, M.-L., Joiner, M.-L. A., Sun, G., Brot, N., Weissbach, H., Heinemann, S. H., Iverson, L., Wu, C., et al. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.032671199 · Cited by 454
Self-citationFighting fruit flies: A model system for the study of aggression
Chen, S., Lee, A. Y., Bowens, N. M., Huber, R., & Kravitz, E. A. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.082102599 · Cited by 412
Phillips, J. P., Campbell, S. D., Michaud, D., Charbonneau, M., & Hilliker, A. J. (1989) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.86.8.2761 · Cited by 389
Two Interdependent TRPV Channel Subunits, Inactive and Nanchung, Mediate Hearing in Drosophila
Gong, Z., Son, W., Chung, Y. D., Kim, J., Shin, D. W., McClung, C. A., Lee, Y., Lee, H. W., Chang, D., Kaang, B., et al. (2004) · Journal of Neuroscience · doi:10.1523/jneurosci.1645-04.2004 · Cited by 359
Resetting the Circadian Clock by Social Experience in Drosophila melanogaster
Levine, J. D., Funes, P., Dowse, H. B., & Hall, J. C. (2002) · Science · doi:10.1126/science.1076008 · Cited by 242
Cited by
Sorted by citations
Perceived social isolation and cognition
Cacioppo, J. T., & Hawkley, L. C. (2009) · Trends in Cognitive Sciences · doi:10.1016/j.tics.2009.06.005 · Cited by 2,144
Social relationships and health: The toxic effects of perceived social isolation
Cacioppo, J. T., & Cacioppo, S. (2014) · Social and Personality Psychology Compass · doi:10.1111/spc3.12087 · Cited by 1,057
Alone in the crowd: The structure and spread of loneliness in a large social network.
Cacioppo, J. T., Fowler, J. H., & Christakis, N. A. (2009) · Journal of Personality and Social Psychology · doi:10.1037/a0016076 · Cited by 908
Unexpected role of interferon-γ in regulating neuronal connectivity and social behaviour
Filiano, A. J., Xu, Y., Tustison, N. J., Marsh, R. L., Baker, W., Smirnov, I., Overall, C. C., Gadani, S. P., Turner, S. D., Weng, Z., et al. (2016) · Nature · doi:10.1038/nature18626 · Cited by 697
Evolutionary mechanisms for loneliness
Cacioppo, J. T., Cacioppo, S., & Boomsma, D. I. (2014) · Cognition and Emotion · doi:10.1080/02699931.2013.837379 · Cited by 576
“For instance, social isolation has been shown to decrease the lifespan of the fruit fly, Drosophila melanogaster (Ruan & Wu, 2008); promote the development of obesity and type 2 diabetes in mice (Nonogaki, Nozue, & Oka, 2007); exacerbate the infarct size and edema and decrease post-stroke survival…”
InfluentialRobinson, G. E., Fernald, R. D., & Clayton, D. F. (2008) · Science · doi:10.1126/science.1159277 · Cited by 595
Cacioppo, J. T., Hawkley, L. C., Norman, G. J., & Berntson, G. G. (2011) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2011.06028.x · Cited by 554
Brosschot, J., Verkuil, B., & Thayer, J. (2018) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph15030464 · Cited by 244
Methods to Assay Drosophila Behavior
Nichols, C. D., Becnel, J., & Pandey, U. B. (2012) · Journal of Visualized Experiments · doi:10.3791/3795 · Cited by 243
Social Interactions in “Simple” Model Systems
Sokolowski, M. B. (2010) · Neuron · doi:10.1016/j.neuron.2010.03.007 · Cited by 201
Lehmann, J., & Boesch, C. (2008) · Animal Behaviour · doi:10.1016/j.anbehav.2008.09.038 · Cited by 165
Chou, K.-L., & Afifi, T. O. (2011) · American Journal of Epidemiology · doi:10.1093/aje/kwr017 · Cited by 134
Reproductive arrest and stress resistance in winter-acclimated Drosophila suzukii
Toxopeus, J., Jakobs, R., Ferguson, L. V., Gariépy, T. D., & Sinclair, B. J. (2016) · Journal of Insect Physiology · doi:10.1016/j.jinsphys.2016.03.006 · Cited by 119
Social context, stress, and plasticity of aging
Amdam, G. V. (2010) · Aging Cell · doi:10.1111/j.1474-9726.2010.00647.x · Cited by 125
Social Neuroscience and its Relationship to Social Psychology
Cacioppo, J. T., Berntson, G. G., & Decety, J. (2010) · Social Cognition · doi:10.1521/soco.2010.28.6.675 · Cited by 123
Chronic social isolation affects thigmotaxis and whole-brain serotonin levels in adult zebrafish
Shams, S., Chatterjee, D., & Gerlai, R. T. (2015) · Behavioural Brain Research · doi:10.1016/j.bbr.2015.05.061 · Cited by 106
COSTS AND BENEFITS OF LIFETIME EXPOSURE TO MATING RIVALS IN MALEDROSOPHILA MELANOGASTER
Bretman, A. J., Westmancoat, J. D., Gage, M. J. G., & Chapman, T. (2013) · Evolution · doi:10.1111/evo.12125 · Cited by 96
Sleep in Drosophila and Its Context
Beckwith, E. J., & French, A. S. (2019) · Frontiers in Physiology · doi:10.3389/fphys.2019.01167 · Cited by 94
Kaur, K., Simon, A. F., Chauhan, V. P. S., & Chauhan, A. (2015) · Behavioural Brain Research · doi:10.1016/j.bbr.2015.02.001 · Cited by 93
Social ageing: exploring the drivers of late-life changes in social behaviour in mammals
Siracusa, E. R., Higham, J. P., Snyder‐Mackler, N., & Brent, L. J. N. (2022) · Biology Letters · doi:10.1098/rsbl.2021.0643 · Cited by 76
Social isolation causes mortality by disrupting energy homeostasis in ants
Koto, A., Mersch, D. P., Hollis, B., & Keller, L. (2015) · Behavioral Ecology and Sociobiology · doi:10.1007/s00265-014-1869-6 · Cited by 67
Social environment mediates cancer progression in Drosophila
Dawson, E. H., Bailly, T. P. M., dos Santos, J., Moreno, C., Devilliers, M., Maroni, B., Sueur, C., Casali, A., Újvári, B., Frédéric Thomas, A., et al. (2018) · Nature Communications · doi:10.1038/s41467-018-05737-w · Cited by 61
Social attraction in Drosophila is regulated by the mushroom body and serotonergic system
Sun, Y., Qiu, R., Li, X., Cheng, Y., Gao, S., Kong, F., Liu, L., & Zhu, Y. (2020) · Nature Communications · doi:10.1038/s41467-020-19102-3 · Cited by 55
What Are the Brain Mechanisms on Which Psychological Processes Are Based?
Cacioppo, J. T., & Jean Decety, A. (2009) · Perspectives on Psychological Science · doi:10.1111/j.1745-6924.2009.01094.x · Cited by 48
Age-related learning deficits can be reversible in honeybees Apis mellifera
Baker, N., Wolschin, F., & Amdam, G. V. (2012) · Experimental Gerontology · doi:10.1016/j.exger.2012.05.011 · Cited by 49
What are social insects telling us about aging?
Parker, J. D. (2024) · ePrints Soton (University of Southampton) · doi:10.25849/myrmecol.news_013:103 · Cited by 44
Sensory Perception and Aging in Model Systems: From the Outside In
Linford, N. J., Kuo, T.-H., Chan, T. P., & Pletcher, S. D. (2011) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev-cellbio-092910-154240 · Cited by 45
Galhardo, L., & Oliveira, R. F. (2013) · Hormones and Behavior · doi:10.1016/j.yhbeh.2013.10.010 · Cited by 41
Kohlmeier, P., Holländer, K., & Meunier, J. (2016) · Journal of Evolutionary Biology · doi:10.1111/jeb.12916 · Cited by 42
Sociogenomics of Cooperation and Conflict during Colony Founding in the Fire Ant Solenopsis invicta
Manfredini, F., Riba‐Grognuz, O., Wurm, Y., Keller, L., Shoemaker, D., & Grozinger, C. M. (2013) · PLoS Genetics · doi:10.1371/journal.pgen.1003633 · Cited by 40
Sex-specific effects of social isolation on ageing in Drosophila melanogaster
Leech, T., Sait, S. M., & Bretman, A. J. (2017) · Journal of Insect Physiology · doi:10.1016/j.jinsphys.2017.08.008 · Cited by 40
Iyengar, A. S. R., Imoehl, J., Ueda, A., Nirschl, J., & Wu, C. (2012) · Journal of Neurogenetics · doi:10.3109/01677063.2012.729626 · Cited by 44
Self-citationThe Genetic Basis of Emotional Behavior: Has the Time Come for a Drosophila Model?
Iliadi, K. G. (2009) · Journal of Neurogenetics · doi:10.1080/01677060802471650 · Cited by 38
Social behavior and aging: A fly model
Brenman‐Suttner, D. B., Yost, R. T., Frame, A. K., Robinson, J. W., Moehring, A. J., & Simon, A. F. (2019) · Genes Brain & Behavior · doi:10.1111/gbb.12598 · Cited by 37
High calorie diet augments age-associats sleep impairment in Drosophila
Yamazaki, M., Tomita, J., Takahama, K., Ueno, T., Mitsuyoshi, M., Sakamoto, E., Kume, S., & Kume, K. (2011) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2011.12.041 · Cited by 35
Early social isolation impairs development, mate choice and grouping behaviour of predatory mites
Schausberger, P., Gratzer, M., & Strodl, M. A. (2017) · Animal Behaviour · doi:10.1016/j.anbehav.2017.02.024 · Cited by 30
Neurophysiological and behavioral synchronization in group-living and sleeping mice
Sotelo, M. I., Markunas, C., Kudlak, T., Kohtz, C., Vyssotski, A. L., Rothschild, G., & Eban-Rothschild, A. (2023) · Current Biology · doi:10.1016/j.cub.2023.11.065 · Cited by 36
Donlea, J. M., & Shaw, P. J. (2009) · Advances in genetics · doi:10.1016/s0065-2660(09)68003-2 · Cited by 30
Liu, G., Nath, T., Linneweber, G. A., Claeys, A., Guo, Z., Li, J., Bengochea, M., Backer, S. D., Weyn, B., Sneyders, M., et al. (2018) · PLoS Computational Biology · doi:10.1371/journal.pcbi.1006410 · Cited by 30
Aging mechanisms—A perspective mostly from Drosophila
Tsurumi, A., & Li, W. X. (2020) · Advanced Genetics · doi:10.1002/ggn2.10026 · Cited by 33
Modelling Tauopathies in Drosophila : Insights from the Fruit Fly
Cowan, C. M., Sealey, M. A., Quraishe, S., Targett, M.-T., Marcellus, K. A., Allan, D. W., & Mudher, A. K. (2011) · International Journal of Alzheimer s Disease · doi:10.4061/2011/598157 · Cited by 26
Early life stress and altered social behaviors: A perspective across species
Parise, L. F., Joseph Burnett, C., & Russo, S. J. (2025) · Neuroscience Research · doi:10.1016/j.neures.2023.11.005 · Cited by 28
Social snails: the effect of social isolation on cognition is dependent on environmental context
Dalesman, S., & Lukowiak, K. D. (2011) · Journal of Experimental Biology · doi:10.1242/jeb.064857 · Cited by 21
Social interactions regulate resource utilization in a Tephritidae fruit fly
Zur, T., Nemny‐Lavy, E., Papadopoulos, N. T., & Nestel, D. (2009) · Journal of Insect Physiology · doi:10.1016/j.jinsphys.2009.05.013 · Cited by 20
Bernard, K. E., Parkes, T. L., & Merritt, T. J. S. (2011) · PLoS ONE · doi:10.1371/journal.pone.0024518 · Cited by 19
Social modulation of ageing: mechanisms, ecology, evolution
Quigley, T. P., & Amdam, G. V. (2021) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.2019.0738 · Cited by 16
Leech, T., McDowall, L., Hopkins, K., Sait, S. M., Harrison, X. A., & Bretman, A. J. (2021) · Molecular Ecology · doi:10.1111/mec.16149 · Cited by 16
The deleterious effects of old social partners on Drosophila lifespan and stress resistance
Lin, Y.-C., Zhang, M., Wang, S., Chieh, C.-W., Shen, P.-Y., Chen, Y., Chang, Y., & Kuo, T.-H. (2022) · npj Aging · doi:10.1038/s41514-022-00081-2 · Cited by 16
Behavioural and Hormonal Stress Responses to Social Separation in Ravens,Corvus corax
Munteanu, A. M., Stocker, M., Stöwe, M., Massen, J. J. M., & Bugnyar, T. (2016) · Ethology · doi:10.1111/eth.12580 · Cited by 18
Neuronal Mechanisms that Drive Organismal Aging Through the Lens of Perception
Gendron, C. M., Chakraborty, T. S., Chung, B. Y., Harvanek, Z. M., Holme, K. J., Johnson, J. C., Lyu, Y., Munneke, A. S., & Pletcher, S. D. (2019) · Annual Review of Physiology · doi:10.1146/annurev-physiol-021119-034440 · Cited by 17
The Effect of Social Isolation on Locomotor Activity in the Houseflies (Musca Domestica)
McCarthy, K., Kjærsgaard, A., Bahrndorff, S., Schou, T. M., Manenti, T., Loeschcke, V., & Pertoldi, C. (2015) · Journal of Insect Behavior · doi:10.1007/s10905-015-9501-9 · Cited by 15
Zhu, J., Ze, S., STANLEY, D. W., & Yang, B. (2014) · Archives of Insect Biochemistry and Physiology · doi:10.1002/arch.21179 · Cited by 15
Social isolation increases male aggression toward females in the field cricket Gryllus bimaculatus
Kuriwada, T. (2015) · Population Ecology · doi:10.1007/s10144-015-0522-1 · Cited by 14
Social perception of young adults prolongs the lifespan of aged Drosophila
Cho, L.-C., Yu, C.-C., & Kao, C.-F. (2021) · npj Aging and Mechanisms of Disease · doi:10.1038/s41514-021-00073-8 · Cited by 13
Manfredini, F., Martínez‐Ruiz, C., Wurm, Y., Shoemaker, D., & Brown, M. J. F. (2021) · Genes Brain & Behavior · doi:10.1111/gbb.12758 · Cited by 14
Group rearing leads to long-term changes in locomotor activity of Drosophila males
Panova, A. A., Bragina, J. V., Danilenkova, L. V., Besedina, N. G., Аркадьевна, К. Е., Александрович, Ф. С., & Камышев, Н. Г. (2013) · Open Journal of Animal Sciences · doi:10.4236/ojas.2013.34a2004 · Cited by 13
Network analyses reveal structure in insect social groups
Alwash, N., & Levine, J. D. (2019) · Current Opinion in Insect Science · doi:10.1016/j.cois.2019.07.001 · Cited by 13
Wikberg, E. C., Ting, N., & Sicotte, P. (2015) · International Journal of Primatology · doi:10.1007/s10764-015-9816-6 · Cited by 12
Öğretmenlerin Okulda Yalnızlıklarının Kariyer Evrelerine Göre İncelenmesi
Bakioğlu, A., & Korumaz, M. (2015) · Eğitim Bilimleri Dergisi · doi:10.15285/ebd.61715 · Cited by 11
Drosophila melanogaster as sentinel organism for hazard identification of environmental contaminants
Wāng, Y. (2025) · Journal of Hazardous Materials · doi:10.1016/j.jhazmat.2025.139600 · Cited by 10
PLIN2-induced ectopic lipid accumulation promotes muscle ageing in gregarious locusts
Guo, S., Hou, L., Dong, L., Nie, X., Kang, L., & Wang, X. (2023) · Nature Ecology & Evolution · doi:10.1038/s41559-023-02059-z · Cited by 10
Ageing effects of social environments in ‘non-social’ insects
Harrison, L. M., Churchill, E. R., Fairweather, M., Smithson, C. H., Chapman, T., & Bretman, A. J. (2024) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.2022.0463 · Cited by 9
Social neuroscience: how a multidisciplinary field is uncovering the biology of human interactions.
Cacioppo, J. T., & Ortigue, S. (2011) · Europe PMC (PubMed Central) · Cited by 10
Wu, M., Li, Y., Miao, Y., Qiao, H., & Wang, Y. (2023) · Journal of drug targeting · doi:10.1080/1061186x.2023.2245582 · Cited by 12
Both age and social environment shape the phenotype of ant workers
Quque, M., Brun, C., Villette, C., Sueur, C., Criscuolo, F., Heintz, D., & Bertile, F. (2023) · Scientific Reports · doi:10.1038/s41598-022-26515-1 · Cited by 12
Starvation promotes odor/feeding-time associations in fliesPreprint
Chouhan, N. S., Wolf, R., & Heisenberg, M. (2017) · Learning & Memory · doi:10.1101/lm.045039.117 · Cited by 9
Iyengar, A. S. R., Ruan, H., & Wu, C. (2021) · eNeuro · doi:10.1523/eneuro.0443-21.2021 · Cited by 8
Self-citationWang, L., Xu, Y., Di, Z., & Roehner, B. M. (2016) · Acta Ecologica Sinica · doi:10.1016/j.chnaes.2016.03.005 · Cited by 8
Chauhan, V. P. S., & Chauhan, A. (2019) · Behavioral and Brain Functions · doi:10.1186/s12993-019-0163-1 · Cited by 7
A Novel Lenticular Arena to Quantify Locomotor Competence in Walking Fruit Flies
MEKDARA, N. T., GOTO, J. J., Choudhury, S. A., Mekdara, P. J., YINGST, N., CAO, Y., BERG, O., & Müller, U. K. (2012) · Journal of Experimental Zoology Part A Ecological Genetics and Physiology · doi:10.1002/jez.1731 · Cited by 6
Bretman, A. J., Chapman, T., Rouse, J. L., & Wigby, S. (2023) · Advances in the study of behavior · doi:10.1016/bs.asb.2022.11.001 · Cited by 5
Ruland, C., Berlandi, J., Eikmeier, K., Weinert, T., Lin, F. J., Ambrée, O., Seggewiß, J., Paulus, W., & Jeibmann, A. (2017) · Genes Brain & Behavior · doi:10.1111/gbb.12451 · Cited by 5
Two novel forms of ERG oscillation in Drosophila : age and activity dependence
Ueda, A., Woods, S., McElree, I. M., O’Harrow, T. C. D. G., Inman, C., Thenuwara, S., Aftab, M., & Iyengar, A. S. R. (2018) · Journal of Neurogenetics · doi:10.1080/01677063.2018.1461866 · Cited by 5
Ueda, A., Iyengar, A. S. R., & Wu, C. (2021) · PubMed Central · doi:10.17912/micropub.biology.000385 · Cited by 4
Self-citationKudo, A. (2021) · Entomological Science · doi:10.1111/ens.12484 · Cited by 4
Navarro, J., Lairla, M. Á. C., Olivera, F. J. N., Gil‐Lacruz, M., Gil‐Lacruz, A. I., & Marijuán, P. C. (2022) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph19031253 · Cited by 4
Rostant, W. G., Mason, J. S., West, N., Maklakov, A. A., & Chapman, T. (2023) · The Journals of Gerontology Series A · doi:10.1093/gerona/glad215 · Cited by 3
Bereft and Left: The interplay between insecure attachment, isolation, and neurobiology
Bell, K., McMillin, K., & Ethridge, L. E. (2022) · Developmental Review · doi:10.1016/j.dr.2022.101020 · Cited by 3
Plant metabolites modulate social networks and lifespan in a sawfly
Singh, P., Brueggemann, L., Janz, S., Saidi, Y., Baruah, G., & Müller, C. (2024) · Journal of Animal Ecology · doi:10.1111/1365-2656.14189 · Cited by 4
The Genetic Architecture of Longevity
Arking, R. (2009) · Humana Press eBooks · doi:10.1007/978-1-60327-507-1_4 · Cited by 3
Bragina, J. V., Goncharova, A. A., Besedina, N. G., Danilenkova, L. V., Аркадьевна, К. Е., & Камышев, Н. Г. (2025) · Archives of Insect Biochemistry and Physiology · doi:10.1002/arch.70022 · Cited by 2
The (un-)Social Brain in Isolation
Fishman, A., Grinin, P., & RILJAK, V. (2025) · Physiological Research · doi:10.33549/physiolres.935565 · Cited by 2
Loneliness influences male and female life expectancy differently in Callosobruchus
Amiri, A., & Bandani, A. R. (2022) · Journal of Stored Products Research · doi:10.1016/j.jspr.2022.101942 · Cited by 3
Stoldt, M., Negroni, M. A., Feldmeyer, B., & Foitzik, S. (2025) · Molecular Ecology · doi:10.1111/mec.17649 · Cited by 3
Perception and Longevity Control in Invertebrate Model Organisms—A Mini-Review of Recent Advances
Pontillo, N., & Lyu, Y. (2025) · Biomolecules · doi:10.3390/biom15020187 · Cited by 2
Mahmoud, S. H., Moselhy, W., El-Khashab, L. A. A., & Seufi, A. M. (2018) · African Entomology · doi:10.4001/003.026.0448 · Cited by 2
Auf das ›Zwischen‹ kommt es an!
Steffens, J. (2020) · Behindertenpädagogik · doi:10.30820/0341-7301-2020-3-260 · Cited by 2
The Social Neuroscience of Social Anxiety Disorder
Syal, S., & Stein, D. J. (2014) · Wiley eBooks · doi:10.1002/9781118653920.ch4 · Cited by 2
Social Neuroscience of the Twenty-First Century
Necka, E. A., Cacioppo, S., & Cacioppo, J. T. (2015) · Elsevier eBooks · doi:10.1016/b978-0-08-097086-8.56020-6 · Cited by 2
Genes and Environments inDrosophilaSex
Hosken, D. J., Bretman, A. J., Goodwin, S. F., & Archer, C. R. (2019) · Wiley eBooks · doi:10.1002/9781119313663.ch6 · Cited by 2
An interaction between cancer progression and social environment in DrosophilaPreprint
Dawson, E. H., Bailly, T. P. M., dos Santos, J., Moreno, C., Devilliers, M., Maroni, B., Sueur, C., Casali, A., Újvári, B., Frédéric Thomas, A., et al. (2017) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/143560 · Cited by 1
Plant metabolites modulate animal social networks and lifespanPreprint
Singh, P., Brueggemann, L., Janz, S., Saidi, Y., Baruah, G., & Müller, C. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.12.20.572488 · Cited by 1
Andreatta, G., Scaramuzza, F., Ćorić, A., Orel, L., & Tessmar‐Raible, K. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.03.12.642703 · Cited by 1
del Moral, R., Navarro, J., del Hoyo, Y. L., Quintero, J. D. G., García‐Campayo, J., & Marijuán, P. C. (2014) · arXiv (Cornell University) · doi:10.48550/arxiv.1405.4136
Holden-Dye, L. M., & Walker, R. J. (2012) · Invertebrate Neuroscience · doi:10.1007/s10158-012-0131-z
Proposed Biological Mediating Mechanisms
Hyyppä, M. T. (2010) · Springer eBooks · doi:10.1007/978-90-481-9606-7_13
Characterizing Genes Associated with Social Interactions in Drosophila melanogaster
Saini, A. (2016) · TSpace (University of Toronto)
Cancer and loneliness in Drosophila
Rivero, A. (2017) · Peer Community in Evolutionary Biology · doi:10.24072/pci.evolbiol.100030
Animal Models of Pathological Aging
Emmons, E. B., Kim, Y.-C., & Narayanan, N. S. (2018) · Wiley eBooks · doi:10.1002/9781118772034.ch4
O’Harrow, T. C. D. G., Ueda, A., Xing, X., & Wu, C. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.11.27.399956
Self-citation
Metadata
- Authors
- Ruan, H., & Wu, C.-F.
- Affiliations
- University of Iowa (US)
- Corresponding author
- Wu, Chun-Fang
- Venue
- Proceedings of the National Academy of Sciences
- Publisher
- National Academy of Sciences
- Published
- 2008-05-27
- Volume
- 105
- Issue
- 21
- Pages
- 7506-7510
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- PMC
- PMC2396722
- OpenAlex
- W2148972618
- Cited by
- 112
- References
- 31
- Citations by year
- 2026: 4 · 2025: 7 · 2024: 3 · 2023: 9 · 2022: 6 · 2021: 8 · 2020: 5 · 2019: 6 · 2018: 7 · 2017: 6 · 2016: 6 · 2015: 8 · 2014: 4 · 2013: 5 · 2012: 5
- FWCI
- 2.23
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Proceedings of the National Academy of Sciences (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institutes of Health
- National Institute of Neurological Disorders and Stroke (R01NS026528, NS-26528)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Aging › Genetics, Aging, and Longevity in Model Organisms
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurobiology and Insect Physiology Research
- Life Sciences › Agricultural and Biological Sciences › Ecology, Evolution, Behavior and Systematics › Animal Behavior and Reproduction
- Keywords
- social interaction, lifespan extension, aging, Cu/Zn superoxide dismutase, mutant SOD1, Drosophila, cohousing, stress tolerance, motor abilities, behavioral interactions, antioxidant enzymes
- MeSH terms
- Alleles, Animals, Animal Communication, Drosophila, Female, Longevity, Male, Mutation, Social Behavior, Superoxide Dismutase, Drosophila Proteins
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review