The DOI matches its Crossref record; 44 of the 44 references it cites were found in a registry or an index.
Cytokinins modulate auxin-induced organogenesis in plants via regulation of the auxin efflux
Open accessAbstract
Postembryonic de novo organogenesis represents an important competence evolved in plants that allows their physiological and developmental adaptation to changing environmental conditions. The phytohormones auxin and cytokinin (CK) are important regulators of the developmental fate of pluripotent plant cells. However, the molecular nature of their interaction(s) in control of plant organogenesis is largely unknown. Here, we show that CK modulates auxin-induced organogenesis (AIO) via regulation of the efflux-dependent intercellular auxin distribution. We used the hypocotyl explants-based in vitro system to study the mechanism underlying de novo organogenesis. We show that auxin, but not CK, is capable of triggering organogenesis in hypocotyl explants. The AIO is accompanied by endogenous CK production and tissue-specific activation of CK signaling. CK affects differential auxin distribution, and the CK-mediated modulation of organogenesis is simulated by inhibition of polar auxin transport. CK reduces auxin efflux from cultured tobacco cells and regulates expression of auxin efflux carriers from the PIN family in hypocotyl explants. Moreover, endogenous CK levels influence PIN transcription and are necessary to maintain intercellular auxin distribution in planta . Based on these findings, we propose a model in which auxin acts as a trigger of the organogenic processes, whose output is modulated by the endogenously produced CKs. We propose that an important mechanism of this CK action is its effect on auxin distribution via regulation of expression of auxin efflux carriers.
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Cites
Ethylene Biosynthesis and its Regulation in Higher Plants
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Local, Efflux-Dependent Auxin Gradients as a Common Module for Plant Organ Formation
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Self-citationChemical regulation of growth and organ formation in plant tissues cultured in vitro.
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The PIN auxin efflux facilitator network controls growth and patterning in Arabidopsis roots
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Self-citationEfflux-dependent auxin gradients establish the apical–basal axis of Arabidopsis
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Regulation of phyllotaxis by polar auxin transport
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Self-citationLateral relocation of auxin efflux regulator PIN3 mediates tropism in Arabidopsis
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Self-citationAn Auxin-Dependent Distal Organizer of Pattern and Polarity in the Arabidopsis Root
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Cited by
In Posidonia oceanica cadmium induces changes in DNA methylation and chromatin patterning
Greco, M., Chiappetta, A., Bruno, L., & Bitonti, M. B. (2012) · Journal of Experimental Botany · doi:10.1093/jxb/err313 · Cited by 538
A Mutually Inhibitory Interaction between Auxin and Cytokinin Specifies Vascular Pattern in Roots
Bishopp, A., Help, H., El-Showk, S., Weijers, D., Scheres, B., Friml, J., Benková, E., Mähönen, A. P., & Helariutta, Y. (2011) · Current Biology · doi:10.1016/j.cub.2011.04.017 · Cited by 441
Self-citationEvolution of cytokinin biosynthesis and degradation
Frebort, I., Kowalska, M., Hluska, T., Frebortova, J., & Galuszka, P. (2011) · Journal of Experimental Botany · doi:10.1093/jxb/err004 · Cited by 422
Cytokinin regulates root meristem activity via modulation of the polar auxin transport
Růžička, K., Šimášková, M., Duclercq, J., Petrášek, J., Zažímalová, E., Simon, S., Friml, J., Van Montagu, M. C. E., & Benková, E. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0900060106 · Cited by 419
Self-citationMoubayidin, L., Di Mambro, R., & Sabatini, S. (2009) · Trends in Plant Science · doi:10.1016/j.tplants.2009.06.010 · Cited by 375
Metadata
- Authors
- Pernisová, M., Klíma, P., Horák, J., Válková, M., Malbeck, J., Souček, P., Reichman, P., Hoyerová, K., Dubová, J., Friml, J., Za;žímalová, E., & Hejátko, J.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 2009-03-03
- Volume
- 106
- Issue
- 9
- Pages
- 3609-3614
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W2007057810
- Cited by
- 253
- References
- 44
- FWCI
- 23.80
- Type
- journal article
- Language
- en
- Open access
- green
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- Pernisová, M., Klíma, P., Horák, J., Válková, M., Malbeck, J., Souček, P., Reichman, P., Hoyerová, K., Dubová, J., Friml, J., Za;žímalová, E., & Hejátko, J. (2009). Cytokinins modulate auxin-induced organogenesis in plants via regulation of the auxin efflux. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.0811539106
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