Identification of protective and broadly conserved vaccine antigens from the genome of extraintestinal pathogenic Escherichia coli

The complete genome sequence of Escherichia coli K-12.

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Sex and virulence in Escherichia coli : an evolutionary perspective

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Extensive mosaic structure revealed by the complete genome sequence of uropathogenic Escherichia coli

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Identification of Vaccine Candidates Against Serogroup B Meningococcus by Whole-Genome Sequencing

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Organised Genome Dynamics in the Escherichia coli Species Results in Highly Diverse Adaptive Paths

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Escherichia coli Induces DNA Double-Strand Breaks in Eukaryotic Cells

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Medical and economic impact of extraintestinal infections due to Escherichia coli: focus on an increasingly important endemic problem

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Expert system for predicting protein localization sites in gram‐negative bacteria

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PSORTb v.2.0: Expanded prediction of bacterial protein subcellular localization and insights gained from comparative proteome analysis

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Structural characterization of the Sel1‐like repeat protein LceB from Legionella pneumophila

Penner, T. V., Cobo, N. L., Patel, D. T., Patel, D., Savchenko, A. V., Brassinga, A. K. C., & Prehna, G. (2023) · Protein Science · doi:10.1002/pro.4889 · Cited by 4

Targeting plasmid-encoded proteins that contain immunoglobulin-like domains to combat antimicrobial resistance

Prieto, A., Miró, L., Margolles, Y., Bernabeu, M., Salguero, D., Merino, S., Tomás, J. M., Sánchez, J. A. C., Pérez‐Bosque, A., Hüttener, M., et al. (2024) · eLife · doi:10.7554/elife.95328 · Cited by 4

Unravelling the Antibiotic Resistance: Molecular Insights and Combating Therapies

Palanikumar, P., Nathan, B., Muthusamy, K., Suganthy, M., Senthil, N., & Sampathrajan, V. (2025) · Applied Biochemistry and Biotechnology · doi:10.1007/s12010-025-05182-8 · Cited by 4

Structure-Based Peptide Mimicry of Tumor-Associated Antigens

Ohtaki, A., Kieber‐Emmons, T., & Murali, R. (2013) · Monoclonal Antibodies in Immunodiagnosis and Immunotherapy · doi:10.1089/mab.2012.0076 · Cited by 4

Understanding the commonalities and differences in genomic organizations across closely related bacteria from an energy perspective

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Photochemical inactivation as an alternative method to produce a whole-cell vaccine for uropathogenic Escherichia coli (UPEC)

Westcott, M. M., Morse, A. E., Troy, G., Blevins, M. W., Wierzba, T. F., & Sanders, J. W. (2024) · Microbiology Spectrum · doi:10.1128/spectrum.03661-23 · Cited by 3

Misconceptions About the Bioarchaeology of Plague

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Immunization with recombinant protein Ag43::UpaH with alum and 1,25(OH)2D3 adjuvants significantly protects Balb/C mice against urinary tract infection caused by uropathogenic Escherichia coli

Habibi, M., Azimi, S., Khoobbakht, D., Roghanian, P., & Karam, M. R. A. (2021) · International Immunopharmacology · doi:10.1016/j.intimp.2021.107638 · Cited by 3

Comparative genomics analysis of statistically significant genomic islands of Helicobacter pylori strains for better understanding the disease prognosis

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Pathogen-Omics: Challenges and Prospects in Research and Clinical Settings

Purkait, D., Hameed, S., & Fatima, Z. (2021) · Springer eBooks · doi:10.1007/978-981-16-0691-5_28 · Cited by 3

Bacterial Genomes and Vaccine Design

Cafardi, V., Telford, J. L., & Serruto, D. (2012) · Springer eBooks · doi:10.1007/978-1-4614-5070-2_2 · Cited by 3

Vaccinology Is Turning into an Omics‐Based Science

Prachi, P., Biagini, M., & Bagnoli, F. (2012) · Drug Development Research · doi:10.1002/ddr.21048 · Cited by 4

Considerations for Vaccine Design in the Postgenomic Era

Maritz-Olivier, C., & Richards, S. A. (2013) · Springer eBooks · doi:10.1007/978-3-319-00978-0_16 · Cited by 2

Unconventional Cyclic di-GMP Signaling in Escherichia coli

Zlatkov, N., & Uhlin, B. E. (2020) · Springer eBooks · doi:10.1007/978-3-030-33308-9_29 · Cited by 2

Meningitis-associated Escherichia coli

Kim, K. S. (2013) · Elsevier eBooks · doi:10.1016/b978-0-12-397048-0.00010-3 · Cited by 2

Microbiota and the Urogenital Tract, Pathogenesis, and Therapies

Tungland, B. C. (2018) · Elsevier eBooks · doi:10.1016/b978-0-12-814649-1.00014-4 · Cited by 2

Deep characterization of Escherichia coli in a cohort of mothers and their infants

de Muinck, & Jacques, É. (2013) · Cited by 2

Sequence alignment with k -bounded matching statisticsPreprint

Mäklin, T., Alanko, J., Biagi, E., & Puglisi, S. J. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.05.19.654936 · Cited by 2

Antibacterial Activity of Adansonia digitata Leaf Extract against Gastrointestinal Bacterial Isolates

Muhammad, J., Muaz, M., Bako, G. D., Musa, B., & Zubair, M. I. (2025) · UMYU Journal of Microbiology Research (UJMR) · doi:10.47430/ujmr.25103.034 · Cited by 1

Adaptive Immune Responses to Infection and Opportunities for Vaccine Development (Rickettsiaceae)

Valbuena, G. (2014) · ASM Press eBooks · doi:10.1128/9781555817336.ch10 · Cited by 1

Therapeutics and Vaccines Against Pathogenic Escherichia coli

Palermo, M. S., Flores‐Figueroa, J., & Paredes‐Paredes, M. (2016) · Springer eBooks · doi:10.1007/978-3-319-45092-6_11 · Cited by 1

Evaluation of virulence factors in clinical isolates of pathogenic E. coli in avian samples in Caloto, Colombia

Galv´an, H. E. D., López, H. M., Ramos, E. M., Yepes-Blandón, J. A., Campo, O., Torres, K. N. Q., Tirado, L. C. E., & Julio, R. G. V. (2023) · Revista Colombiana de Biotecnología · doi:10.15446/rev.colomb.biote.v25n2.110727 · Cited by 1

Recent Insights into the Synthesis of Oligosaccharides from Escherichia coli: Review

Sharma, A., Rabha, P., & Panchadhayee, R. (2024) · Current Organic Chemistry · doi:10.2174/0113852728322510240711045944 · Cited by 1

Immunoinformatics-driven design and computational analysis of a multiepitope vaccine targeting uropathogenic Escherichia coli

Khalid, H., & Shityakov, S. (2024) · In Silico Pharmacology · doi:10.1007/s40203-024-00288-z · Cited by 1

Design of New Vaccines in the Genomic and Post-genomic Era

Serino, L., Seib, K. L., & Pizza, M. (2012) · Springer eBooks · doi:10.1007/978-94-007-4543-8_1 · Cited by 1

New Approaches for Needed Vaccines: Bacteria

MacLennan, C. A., Mutreja, A., & Gordon Dougan, B. (2016) · Elsevier eBooks · doi:10.1016/b978-0-12-802174-3.00016-3 · Cited by 1

Population Phylogenomics of Extraintestinal PathogenicEscherichia coli

Tourret, J., & Denamur, É. (2016) · ASM Press eBooks · doi:10.1128/9781555817404.ch11 · Cited by 1

To Move or to Convene : Regulatory Circuits of Mat Fimbriae in Escherichia coli

Lehti, T. A. (2012) · Työväentutkimus Vuosikirja · Cited by 1

Phylogenetic and genomic characterization of porcine enterotoxigenic Escherichia coli

Shepard, S. M. (2011) · University of Minnesota Digital Conservancy (University of Minnesota) · Cited by 1

Biofilm-Forming Ability, Antibiotic Resistance and Phylogeny of Escherichia Coli Isolated from Extra Intestinal Infections of Humans, Dogs, and ChickensPreprint

Gunathilake, K. K., Dewasmika, P., Sandaruwan, M., Neelawala, D., Madhumali, D., Dissanayake, N., Priynatha, R., Prasada, P. V. P., & Dissanayake, D. A. (2023) · SSRN Electronic Journal · doi:10.2139/ssrn.4601825 · Cited by 1

Microbial Vaccine Design: The Reverse Vaccinology Approach

Rosini, R., Barocchi, M. A., & Rappuoli, R. (2011) · doi:10.1002/9781118023648.ch1

Regulation of Expression of Enterohemolysin Toxin by the Global Repressor HNS and Characterization of a New Class of Protein Produced by Shiga Toxin-Producing Escherichia Coli

Rogers, M. T. (2012) · ScholarWorks - WMU (Western Michigan University)

Characterization of a novel Escherichia coli IgA-binding antigen impairing neutrophil activation

Pastorello, I. (2012) · Padua Research Archive (University of Padova)

Functional genotyping of extraintestinal pathogenic E.coli (ExPEC) belonging to the highly pathogenic sequence type 95 reveals the zoonotic nature of human and avian strains

Nandanwar, N. (2014) · Universitätsbibliothek der FU Berlin Hochschulschriftenstelle u. Dokumentenserver · doi:10.17169/refubium-14004

Isolation of novel CFT073 genes c1680 and c3911 and further analysis of previously isolated novel genes for preliminary testing into potential vaccine antigen targets for extraintestinal pathogenic Escherichia coli.

Dorrington, E., Kelly, K., Mackay, M., & Pedwell, R. K. (2013)

Neonatal Septicemic Escherichia coli Protease (SslE) Induces Macrophage Activation and Polarization Through Induction of ROS and NO

Tapader, R., & Pal, A. (2019) · Springer eBooks · doi:10.1007/978-981-13-8763-0_19

The distribution of escherichia coli in pregnant women and antimicrobial susceptibility patterns of the isolates in selected rural areas in Namibia

Nangolo, L. (2018)

Las partículas similares a virus (VLPs, virus-likeparticles) y su empleo en vacunología

Ganzó, A. D., Borio, C. S., Pastorini, M., Lozano, M. E., & Goñi, S. E. (2018) · Divulgatio Perfiles académicos de posgrado · doi:10.48160/25913530di05.58

Rationales for including adjuvants in vaccines

Schijns, V. E. C. J., & Lavelle, E. C. (2011) · doi:10.2217/ebo.11.10

Vaccine Design Strategies: Pathogens to Genomes

McMullan, N. (2021) · Royal Society of Chemistry eBooks · doi:10.1039/9781788017862-00440

Artificial Intelligence and Machine Learning for Prediction and Analysis of Genomic Islands

Shukla, A., Mishra, N. K., & Choudhary, A. (2023) · Springer eBooks · doi:10.1007/978-981-19-9342-8_17

An Overview of Genomic Islands’ Main Features and Computational Prediction: The CMNR Group of Bacteria As a Case Study

Rodrigues, T. C. V., Jaiswal, A. K., Aburjaile, F. F., Almeida, C. A., Carvalho, R. D. D. O., de Paula, J. A., Santos, R. P. S., Dominici, F. V., Felice, A. G., Marques, P. H., et al. (2023) · Springer eBooks · doi:10.1007/978-981-19-9342-8_3

Progress toward the development of an effective vaccine for Extraintestinal pathogenic E. coli (ExPEC): The application of the multiple-protein subunits vaccine in different murine modelsPreprint

Xing, Y., Clark, J. R., Chang, J. D., Zulk, J. J., Chirman, D. M., Piedra, F.-A., Patras, K. A., & Maresso, A. W. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.05.31.543151

Targeting plasmid-encoded proteins that contain immunoglobulin-like domains to combat antimicrobial resistancePreprint

Prieto, A., Miró, L., Margolles, Y., Bernabeu, M., Salguero, D., Merino, S., Tomás, J. M., Sánchez, J. A. C., Pérez‐Bosque, A., Hüttener, M., et al. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.12.12.571265

Targeting plasmid-encoded proteins that contain immunoglobulin-like domains to combat antimicrobial resistancePreprint

Prieto, A., Miró, L., Margolles, Y., Bernabeu, M., Salguero, D., Merino, S., Tomás, J. M., Sánchez, J. A. C., Pérez‐Bosque, A., Hüttener, M., et al. (2024) · eLife · doi:10.7554/elife.95328.1

Targeting plasmid-encoded proteins that contain immunoglobulin-like domains to combat antimicrobial resistancePreprint

Prieto, A., Miró, L., Margolles, Y., Bernabeu, M., Salguero, D., Merino, S., Tomás, J. M., Sánchez, J. A. C., Pérez‐Bosque, A., Hüttener, M., et al. (2024) · eLife · doi:10.7554/elife.95328.2

A descriptor-free machine learning framework to improve antigen discovery for bacterial pathogens

Podda, M., Savojardo, C., Martelli, P. L., Casadio, R., Sîrbu, A., Priami, C., & Brozzi, A. (2025) · PLoS ONE · doi:10.1371/journal.pone.0323895

Monitoring of vaccine targets and interventions using global genome data: vaccines.watchPreprint

David, S., Abudahab, K., Couto, N., Daningrat, W. O. D., Yeats, C., Molloy, A., Ashton, P., Alikhan, N.-F., & Aanensen, D. M. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.06.13.659488 · Cited by 1

Systemic IgG responses to glycosylated mucinase YghJ after experimental enterotoxigenic Escherichia coli infection

Riaz, S., Steinsland, H., Boysen, A., & Hanevik, K. (2025) · Gut Pathogens · doi:10.1186/s13099-025-00748-7 · Cited by 1

Substrate Selectivity and Molecular Adaptation in the Outer Membrane Proteases of Yersinia pestis and Salmonella enterica

Haiko, J. (2010)

A matched case-control study on Escherichia coli factors contributing to sepsis and septic shock in bacteraemic patients

Maldonado, N. A., López-Hernández, I., Valik, J. K., López-Cortés, L. E., Pérez-Crespo, P. M. M., García-Montaner, A., Alcalde‐Rico, M., Sousa-Domínguez, A., Jover-Sáenz, A., Goikoetxea, J., et al. (2026) · Communications Medicine · doi:10.1038/s43856-025-01364-x

Engineering Escherichia coli to biosynthesize O-polysaccharide-derived recombinant glycoconjugate vaccines against pathogenic serotypes O8 and O9a

Li, Z., Ma, G., Liu, R. T., Wang, X., Wang, Y., Zhao, X., Meng, Q., Xie, L., Li, X., Liu, S., et al. (2026) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2026.125009

Sequencing of the invasive E. coli strain BEN2908 isolated from poultry: A comparative investigation of genomic regions shared with intestinal and extraintestinal model E. coli strains

Martins, T. W., Trotereau, A., Lahnig-Jacques, S., Branger, M., Houle, S., Dozois, C. M., Pavanelo, D. B., Horn, F., & Schouler, C. (2026) · PLoS ONE · doi:10.1371/journal.pone.0342894

Biosynthesis of a Polysaccharide-based Glycoconjugate Vaccine against Neonatal Meningitis-Causing Escherichia coli O45

Wang, Y., Liu, H., Wang, Y., Wang, B., Fang, X., Wang, H., Liu, L., & Tan, H. (2026) · ACS Synthetic Biology · doi:10.1021/acssynbio.5c00829

Taxano-genomics, a strategy incorporating genomic data into the taxonomic description of human bacteria

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Proteomic identification of novel adhesins in enterohaemorrhagic Escherichia coli 0157 -- H7 in a strategy of preventing intestinal colonization

Monteiro, R. (2018) · doi:10.70675/3c4ce78cz0b76z448fzbbf1z818babc5e794

Caractérisation du rôle de l'Antigène 43 dans le processus de colonisation d'Escherichia coli O157∶H7

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Architecture of the type II secretion systemPreprint

Tayebinia, M., Ghanem, N., Zhang, H., Yang, Y., Fornili, A., Shevchik, V. E., Dabari, V., & Pickersgill, R. W. (2026) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2026.05.07.723501

High-Risk ExPEC from Commensal Phylogroup A: Genomic Characterization of a Bovine Meningoencephalitis Isolate, BN01

Ren, J., Qin, H., Yan, W., Qi, Y., Du, D., Wang, P., Yan, W., & Jiang, J. (2026) · Microorganisms · doi:10.3390/microorganisms14071586

Revisiting the type II secretion system: it is more than you might think

Cianciotto, N. P., Mayoral, J., & Garnett, J. A. (2026) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.00118-25

Validation of electrochemiluminescent (ECL)-based immunoassay to determine the levels of antibodies against Escherichia coli O-lipopolysaccharide antigens

Kamdar, M., Shah, V., Janssen, S., Domínguez, E. G., Davies, T. A., & van den Dobbelsteen, G. (2026) · Microbiology Spectrum · doi:10.1128/spectrum.00863-26

Identification of Candidates for a Subunit Vaccine against Extraintestinal Pathogenic Escherichia coli

Durant, L., Métais, A., Soulama-Mouze, C., Genevard, J.-M., Nassif, X., & Escaich, S. (2006) · Infection and Immunity · doi:10.1128/iai.01269-06 · Cited by 64

Characterization of a novel Escherichia coli IgA-binding antigen impairing neutrophil activation

Pastorello, I. (2012) · Padua Research Archive (University of Padova)

A Novel Protective Vaccine Antigen from the Core Escherichia coli Genome

Moriel, D. G., Tan, L., Goh, K., Phan, M., Ipe, D., Lo, A. W., Peters, K. M., Ulett, G., Beatson, S., & Schembri, M. (2016) · Msphere · doi:10.1128/msphere.00326-16 · Cited by 40

Progress toward a vaccine for extraintestinal pathogenic E. coli (ExPEC) II: efficacy of a toxin-autotransporter dual antigen approach

Xing, Y., Clark, J. R., Chang, J. D., Zulk, J. J., Chirman, D. M., Piedra, F.-A., Vaughan, E. E., Santos, H. H., Patras, K. A., & Maresso, A. W. (2024) · Infection and Immunity · doi:10.1128/iai.00440-23 · Cited by 6

A Multiepitope Subunit Vaccine Conveys Protection against Extraintestinal Pathogenic Escherichia coli in Mice

Wieser, A., Romann, E., Magistro, G., Hoffmann, C., Nörenberg, D., Weinert, K., & Schubert, S. (2010) · Infection and Immunity · doi:10.1128/iai.00174-10 · Cited by 92