The DOI matches its Crossref record; 41 of the 41 references it cites were found in a registry or an index.
A functional genomics approach toward the understanding of secondary metabolism in plant cells
Open accessAbstract
Despite the tremendous importance of secondary metabolites for humans as for the plant itself, plant secondary metabolism remains poorly characterized. Here, we present an experimental approach, based on functional genomics, to facilitate gene discovery in plant secondary metabolism. Targeted metabolite analysis was combined with cDNA-amplified fragment length polymorphism-based transcript profiling of jasmonate-elicited tobacco Bright yellow 2 cells. Transcriptome analysis suggested an extensive jasmonate-mediated genetic reprogramming of metabolism, which correlated well with the observed shifts in the biosynthesis of the metabolites investigated. This method, which in addition to transcriptome data also generates gene tags, in the future might lead to the creation of novel tools for metabolic engineering of medicinal plant systems in general.
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Cited by
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Metadata
- Authors
- Goossens, A., Häkkinen, S. T., Laakso, I., Seppänen-Laakso, T., Biondi, S., De Sutter, V., Lammertyn, F., Nuutila, A. M., Söderlund, H., Zabeau, M., Inzé, D., & Oksman-Caldentey, K.-M.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 2003-06-25
- Volume
- 100
- Issue
- 14
- Pages
- 8595-8600
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W2048898143
- Cited by
- 406
- References
- 41
- FWCI
- 6.65
- Type
- journal article
- Language
- en
- Open access
- green
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- Goossens, A., Häkkinen, S. T., Laakso, I., Seppänen-Laakso, T., Biondi, S., De Sutter, V., Lammertyn, F., Nuutila, A. M., Söderlund, H., Zabeau, M., Inzé, D., & Oksman-Caldentey, K.-M. (2003). A functional genomics approach toward the understanding of secondary metabolism in plant cells. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.1032967100
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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