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Biology of Amyloid: Structure, Function, and Regulation

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Molecular basis for amyloid-β polymorphism

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Annular Protofibrils Are a Structurally and Functionally Distinct Type of Amyloid Oligomer

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Antiparallel β-sheet architecture in Iowa-mutant β-amyloid fibrils

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Oligomeric Intermediates in Amyloid Formation: Structure Determination and Mechanisms of Toxicity

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Comparison of Alzheimer Aβ(1–40) and Aβ(1–42) amyloid fibrils reveals similar protofilament structures

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Amyloid β-Protein Dimers Rapidly Form Stable Synaptotoxic Protofibrils

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Aβ42 Neurotoxicity Is Mediated by Ongoing Nucleated Polymerization Process Rather than by Discrete Aβ42 Species*

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α-Helix targeting reduces amyloid-β peptide toxicity

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Evidence of the Existence of Micelles in the Fibrillogenesis of β-Amyloid Peptide

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Solid‐State NMR Spectroscopic Investigation of Aβ Protofibrils: Implication of a β‐Sheet Remodeling upon Maturation into Terminal Amyloid Fibrils

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P4‐316: Stabilization of neurotoxic Alzheimer amyloid‐beta oligomers by protein engineering

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Sequestration of the Aβ Peptide Prevents Toxicity and Promotes Degradation In Vivo

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Mutagenic analysis of the nucleation propensity of oxidized Alzheimer's β‐amyloid peptide

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Structural Basis of β‐Amyloid‐Dependent Synaptic Dysfunctions

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Probing the origins, diagnosis and treatment of amyloid diseases using antibodies

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Demonstration of a common artifact in immunosorbent assays of brain extracts: Development of a solid-phase extraction protocol to enable measurement of amyloid-β from wild-type rodent brain

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Pattern Recognition with a Fibril-Specific Antibody Fragment Reveals the Surface Variability of Natural Amyloid Fibrils

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Amyloid Fibril Recognition with the Conformational B10 Antibody Fragment Depends on Electrostatic Interactions

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Phosphate and HEPES buffers potently affect the fibrillation and oligomerization mechanism of Alzheimer’s Aβ peptide

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Towards an understanding of amyloid-β oligomers: characterization, toxicity mechanisms, and inhibitors

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Chemical Fluorescent Probe for Detection of Aβ Oligomers

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Brazilin inhibits amyloid β-protein fibrillogenesis, remodels amyloid fibrils and reduces amyloid cytotoxicity

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Visualizing and trapping transient oligomers in amyloid assembly pathways

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Quantifying misfolded protein oligomers as drug targets and biomarkers in Alzheimer and Parkinson diseases

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Fabrication of an antibody-aptamer sandwich assay for electrochemical evaluation of levels of β-amyloid oligomers

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Role of aromatic amino acids in amyloid self-assembly

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Stereochemistry and amyloid inhibition: Asymmetric triplex metallohelices enantioselectively bind to Aβ peptide

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Protein structural and surface water rearrangement constitute major events in the earliest aggregation stages of tau

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Structural Insights into Aβ42 Oligomers Using Site-directed Spin Labeling

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Single-Domain Antibodies as Therapeutic and Imaging Agents for the Treatment of CNS Diseases

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Antibody-Based Drugs and Approaches Against Amyloid-β Species for Alzheimer’s Disease Immunotherapy

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An infrared sensor analysing label-free the secondary structure of the Abeta peptide in presence of complex fluids

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Antiparallel Triple-strand Architecture for Prefibrillar Aβ42 Oligomers

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Detection of Aβ Monomers and Oligomers: Early Diagnosis of Alzheimer's Disease

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p31-43 Gliadin Peptide Forms Oligomers and Induces NLRP3 Inflammasome/Caspase 1- Dependent Mucosal Damage in Small Intestine

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Camelid single-domain antibody fragments: Uses and prospects to investigate protein misfolding and aggregation, and to treat diseases associated with these phenomena

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Conformation-specific antibodies to target amyloid β oligomers and their application to immunotherapy for Alzheimer’s disease

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An ultra‐sensitive immunoassay detects and quantifies soluble Aβ oligomers in human plasma

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Ac-LVFFARK-NH 2 conjugation to β-cyclodextrin exhibits significantly enhanced performance on inhibiting amyloid β-protein fibrillogenesis and cytotoxicity

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A Generic Method for Design of Oligomer-Specific Antibodies

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Diverse Structural Conversion and Aggregation Pathways of Alzheimerʼs Amyloid-β (1–40)

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Preparation of fibril nuclei of beta-amyloid peptides in reverse micelles

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Binding affinity prediction of nanobody–protein complexes by scoring of molecular dynamics trajectories

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Design and Optimization of Anti-amyloid Domain Antibodies Specific for β-Amyloid and Islet Amyloid Polypeptide

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Inhibition of Protein Aggregation by Several Antioxidants

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A Novel Multifunctional Compound Camellikaempferoside B Decreases Aβ Production, Interferes with Aβ Aggregation, and Prohibits Aβ-Mediated Neurotoxicity and Neuroinflammation

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An Atomistic View of Amyloidogenic Self-assembly: Structure and Dynamics of Heterogeneous Conformational States in the Pre-nucleation Phase

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High-affinity Anticalins with aggregation-blocking activity directed against the Alzheimer β-amyloid peptide

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Chemically-defined camelid antibody bioconjugate for the magnetic resonance imaging of Alzheimer's disease

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In Vivo Near-Infrared Fluorescence Imaging Selective for Soluble Amyloid β Aggregates Using y-Shaped BODIPY Derivative

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Rational design of a “sense and treat” system to target amyloid aggregates related to Alzheimer’s disease

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Cognitive Enhancers (Nootropics). Part 3: Drugs Interacting with Targets other than Receptors or Enzymes. Disease-modifying Drugs

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Targeting Pathological Amyloid Aggregates with Conformation-Sensitive Antibodies

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Conformational selection in amyloid-based immunotherapy: Survey of crystal structures of antibody-amyloid complexes

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