The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.
Widespread dynamic DNA methylation in response to biotic stress
Open accessAbstract
Regulation of gene expression by DNA methylation is crucial for defining cellular identities and coordinating organism-wide developmental programs in many organisms. In plants, modulation of DNA methylation in response to environmental conditions represents a potentially robust mechanism to regulate gene expression networks; however, examples of dynamic DNA methylation are largely limited to gene imprinting. Here we report an unexpected role for DNA methylation in regulation of the Arabidopsis thaliana immune system. Profiling the DNA methylomes of plants exposed to bacterial pathogen, avirulent bacteria, or salicylic acid (SA) hormone revealed numerous stress-induced differentially methylated regions, many of which were intimately associated with differentially expressed genes. In response to SA, transposon-associated differentially methylated regions, which were accompanied by up-regulation of 21-nt siRNAs, were often coupled to transcriptional changes of the transposon and/or the proximal gene. Thus, dynamic DNA methylation changes within repetitive sequences or transposons can regulate neighboring genes in response to SA stress.
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Cites
Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources
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Human DNA methylomes at base resolution show widespread epigenomic differences
Lister, R., Pelizzola, M., Dowen, R. H., Hawkins, R. D., Hon, G., Tonti-Filippini, J., Nery, J. R., Lee, L., Ye, Z., Ngo, Q.-M., et al. (2009) · Nature · doi:10.1038/nature08514 · Cited by 4,673
Self-citationTransgenerational Inheritance of an Acquired Small RNA-Based Antiviral Response in C. elegans
Rechavi, O., Minevich, G., & Hobert, O. (2011) · Cell · doi:10.1016/j.cell.2011.10.042 · Cited by 351
Bernatavichute, Y. V., Zhang, X., Cokus, S., Pellegrini, M., & Jacobsen, S. E. (2008) · PLoS ONE · doi:10.1371/journal.pone.0003156 · Cited by 333
Cited by
Systemic Acquired Resistance: Turning Local Infection into Global Defense
Fu, Z. Q., & Dong, X. (2013) · Annual Review of Plant Biology · doi:10.1146/annurev-arplant-042811-105606 · Cited by 1,524
Patterns of population epigenomic diversity
Schmitz, R. J., Schultz, M. D., Urich, M. A., Nery, J. R., Pelizzola, M., Libiger, O., Alix, A., McCosh, R. B., Chen, H., Schork, N. J., et al. (2013) · Nature · doi:10.1038/nature11968 · Cited by 572
Self-citationThe Epigenome and Transcriptional Dynamics of Fruit Ripening
Giovannoni, J., Nguyen, C., Ampofo, B., Zhong, S., & Fei, Z. (2017) · Annual Review of Plant Biology · doi:10.1146/annurev-arplant-042916-040906 · Cited by 474
Dynamics and biological relevance of DNA demethylation in Arabidopsis antibacterial defense
Yu, A., Lepère, G., Jay, F., Wang, J., Bapaume, L., Wang, Y., Abraham, A.-L., Penterman, J., Fischer, R. L., Voinnet, O., et al. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1211757110 · Cited by 462
What we still don't know about invasion genetics
Bock, D. G., Caseys, C., Cousens, R. D., Hahn, M. A., Heredia, S. M., Hübner, S., Turner, K. G., Whitney, K. D., & Rieseberg, L. H. (2015) · Molecular Ecology · doi:10.1111/mec.13032 · Cited by 441
Metadata
- Authors
- Dowen, R. H., Pelizzola, M., Schmitz, R. J., Lister, R., Dowen, J. M., Nery, J. R., Dixon, J. E., & Ecker, J. R.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 2012-06-25
- Volume
- 109
- Issue
- 32
- Pages
- E2183-91
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W2168031748
- Cited by
- 1,005
- References
- 6
- FWCI
- 24.05
- Type
- journal article
- Language
- en
- Open access
- green
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- Dowen, R. H., Pelizzola, M., Schmitz, R. J., Lister, R., Dowen, J. M., Nery, J. R., Dixon, J. E., & Ecker, J. R. (2012). Widespread dynamic DNA methylation in response to biotic stress. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.1209329109
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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