Cited by 808Statistical Methods and Bayesian InferenceMeta-analysis and systematic reviewsProbability and Statistical Research

Revised standards for statistical evidence

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Johnson, Valen E.·2013·Proceedings of the National Academy of Sciences

Abstract

Recent advances in Bayesian hypothesis testing have led to the development of uniformly most powerful Bayesian tests, which represent an objective, default class of Bayesian hypothesis tests that have the same rejection regions as classical significance tests. Based on the correspondence between these two classes of tests, it is possible to equate the size of classical hypothesis tests with evidence thresholds in Bayesian tests, and to equate P values with Bayes factors. An examination of these connections suggest that recent concerns over the lack of reproducibility of scientific studies can be attributed largely to the conduct of significance tests at unjustifiably high levels of significance. To correct this problem, evidence thresholds required for the declaration of a significant finding should be increased to 25-50:1, and to 100-200:1 for the declaration of a highly significant finding. In terms of classical hypothesis tests, these evidence standards mandate the conduct of tests at the 0.005 or 0.001 level of significance.

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  1. [2]Naik G. (December 2, 2011) Scientists’ elusive goal: Reproducing study results. Wall Street Journal, Health Section.
  2. [11]Jeffreys H. Theory of Probability. 3rd Ed. Oxford: Oxford Univ Press; 1961. [Google Scholar]

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Authors
Johnson, V. E.
Affiliations
Texas A&M University (US)
Corresponding author
Johnson, Valen E.
Venue
Proceedings of the National Academy of Sciences
Published
2013-11-11
Volume
110
Issue
48
Pages
19313-19317
ISSN
  • 0027-8424 (ISSN-L)
  • 1091-6490
OpenAlex
W1970588407
Cited by
808
References
22
Citations by year
2026: 11 · 2025: 17 · 2024: 30 · 2023: 52 · 2022: 48 · 2021: 55 · 2020: 52 · 2019: 67 · 2018: 94 · 2017: 115 · 2016: 94 · 2015: 86 · 2014: 85 · 2013: 2
FWCI
78.55
Type
journal article
Language
en
Open access
Locations
  • Proceedings of the National Academy of Sciences (publishedVersion)
  • Europe PMC (PubMed Central) (publishedVersion)
  • PubMed Central (publishedVersion)
  • PubMed (publishedVersion)
  • OakTrust (Texas A&M University Libraries) (submittedVersion)
Funders
National Cancer Institute (R01CA158113)
Topics
  • Physical Sciences › Mathematics › Statistics and Probability › Statistical Methods and Bayesian Inference
  • Social Sciences › Decision Sciences › Statistics, Probability and Uncertainty › Meta-analysis and systematic reviews
  • Physical Sciences › Mathematics › Statistics and Probability › Probability and Statistical Research
Keywords
Bayesian hypothesis testing, Bayes factor, p-values, significance level, reproducibility, evidence thresholds
MeSH terms
Bayes Theorem, Statistics as Topic, Reproducibility of Results, Models, Statistical

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