The DOI matches its Crossref record; 47 of the 47 references it cites were found in a registry or an index.
Neural correlates of the LSD experience revealed by multimodal neuroimaging
Open accessAbstract
Significance: Lysergic acid diethylamide (LSD), the prototypical “psychedelic,” may be unique among psychoactive substances. In the decades that followed its discovery, the magnitude of its effect on science, the arts, and society was unprecedented. LSD produces profound, sometimes life-changing experiences in microgram doses, making it a particularly powerful scientific tool. Here we sought to examine its effects on brain activity, using cutting-edge and complementary neuroimaging techniques in the first modern neuroimaging study of LSD. Results revealed marked changes in brain blood flow, electrical activity, and network communication patterns that correlated strongly with the drug’s hallucinatory and other consciousness-altering properties. These results have implications for the neurobiology of consciousness and for potential applications of LSD in psychological research.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The cited source doesn’t support the claim as written.
In the citing paper
“Such disruption is believed to be associated with the experience of ego dissolution [71].”
From Mindfulness meditation and psychedelics: potential synergies and commonalities (2023) · cites this paper as [71]
Checked by a reasoning model — may be wrong.
Experimental — accuracy not yet measuredThe source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“In the field of psychedelic neuroscience, reduced mPFC-PCC connectivity as well as DMN deactivation and disintegration have been demonstrated post-acutely after the administration of psilocybin, LSD and ayahuasca (45, 46, 57), while long-term ayahuasca users demonstrated thinning of the PCC (117).”
From Examining the Potential Synergistic Effects Between Mindfulness Training and Psychedelic-Assisted Therapy (2021) · cites this paper as [46]
Experimental — accuracy not yet measuredThe cited source says what the claim attributes to it.
In the citing paper
“In contrast, arterial spin labeling (ASL) measurements of cerebral perfusion indicated that LSD (1) increased CBF in visual cortex of human volunteers [139].”
From Molecular and Functional Imaging Studies of Psychedelic Drug Action in Animals and Humans. (2021) · cites this paper as [139]
The cited source says what the claim attributes to it.
In the citing paper
“The increased CBF and the extent of the functional connectivity of the visual cortex correlated with the intensity of visual hallucinations; we suppose that anesthesia may have interfered in the effects of LSD (1) on CBF in the pig PET study.”
From Molecular and Functional Imaging Studies of Psychedelic Drug Action in Animals and Humans. (2021) · cites this paper as [139]
The cited source says what the claim attributes to it.
In the citing paper
“Certain psychedelic studies have further correlated these transient connectivity changes within the DMN with subjective measures of drug-induced ego-dissolution (46, 115).”
From Examining the Potential Synergistic Effects Between Mindfulness Training and Psychedelic-Assisted Therapy (2021) · cites this paper as [46]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Shaping Functional Architecture by Oscillatory Alpha Activity: Gating by Inhibition
Jensen, O., & Mazaheri, A. (2010) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2010.00186 · Cited by 3,237
Kapur, S. (2003) · American Journal of Psychiatry · doi:10.1176/appi.ajp.160.1.13 · Cited by 2,813
(1995) · PubMed · Cited by 1,320
Carhart-Harris, R. L., Leech, R., Hellyer, P. J., Shanahan, M., Feilding, A., Tagliazucchi, E., Chialvo, D. R., & Nutt, D. (2014) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2014.00020 · Cited by 1,252
Self-citationPilot Study of Psilocybin Treatment for Anxiety in Patients With Advanced-Stage Cancer
Grob, C. S., Danforth, A. L., Chopra, G. S., Hagerty, M., McKay, C. R., Halberstadt, A. L., & Greer, G. R. (2011) · Archives of General Psychiatry · doi:10.1001/archgenpsychiatry.2010.116 · Cited by 1,206
Neural correlates of the psychedelic state as determined by fMRI studies with psilocybin
Carhart-Harris, R. L., Erritzoe, D., Williams, T., Stone, J. M., Reed, L. J., Colasanti, A., Tyacke, R. J., Leech, R., Malizia, A. L., Murphy, K., et al. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1119598109 · Cited by 1,172
Self-citationPsilocybin-assisted treatment for alcohol dependence: A proof-of-concept study
Bogenschutz, M. P., Forcehimes, A. A., Pommy, J. A., Wilcox, C. E., Barbosa, P., & Strassman, R. J. (2015) · Journal of Psychopharmacology · doi:10.1177/0269881114565144 · Cited by 1,151
Pilot study of the 5-HT 2A R agonist psilocybin in the treatment of tobacco addiction
Johnson, M. W., Garcia-Romeu, A., Cosimano, M. P., & Griffiths, R. R. (2014) · Journal of Psychopharmacology · doi:10.1177/0269881114548296 · Cited by 914
Gasser, P., Holstein, D., Michel, Y., Doblin, R., Yazar-Klosinski, B., Passie, T., & Brenneisen, R. (2014) · Journal of Nervous & Mental Disease · doi:10.1097/nmd.0000000000000113 · Cited by 750
Psychometric evaluation of the altered states of consciousness rating scale (OAV)
Studerus, E., Gamma, A., & Vollenweider, F. X. (2010) · PLoS ONE · doi:10.1371/journal.pone.0012412 · Cited by 683
Research works printed but not linked: 1
- RR Monroe, RG Heath, Effects of lysergic acid and various derivatives on depth and cortical electrograms. J Neuropsychiatry 3, 75–82 (1961).
Cited by
Sorted by citations
Items 201–300 of 856
van Elk, M., Fejer, G., Lempe, P., Prochazkova, L., Kuchař, M., Hájková, K., & Marschall, J. (2021) · Psychopharmacology · doi:10.1007/s00213-021-05857-0 · Cited by 50
Isness: Using Multi-Person VR to Design Peak Mystical Type Experiences Comparable to Psychedelics
Glowacki, D. R., Wonnacott, M. D., Freire, R., Glowacki, B. R., Gale, E. M., Pike, J. E., de Haan, T., Chatziapostolou, M., & Metatla, O. (2020) · Proceedings of the 2020 CHI Conference on Human Factors in Computing Systems · doi:10.1145/3313831.3376649 · Cited by 54
An introduction to psychedelic neuroscience
Calvey, T., & Howells, F. M. (2018) · Progress in brain research · doi:10.1016/bs.pbr.2018.09.013 · Cited by 57
Magaraggia, I., Kuiperes, Z., & Schreiber, R. (2021) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2021.107467 · Cited by 51
Königsmark, V., Bergmann, J., & Reeder, R. (2021) · Cortex · doi:10.1016/j.cortex.2021.05.007 · Cited by 50
RETRACTED ARTICLE: A mechanistic model of the neural entropy increase elicited by psychedelic drugs
Herzog, R. A., Mediano, P. A. M., Rosas, F. E., Carhart-Harris, R. L., Perl, Y. S., Tagliazucchi, E., & Cofré, R. (2020) · Scientific Reports · doi:10.1038/s41598-020-74060-6 · Cited by 49
Self-citationRetractedReview of otential sychedelic reatments for PTSD
Henner, R. L., Keshavan, M. S., & Hill, K. P. (2022) · Journal of the Neurological Sciences · doi:10.1016/j.jns.2022.120302 · Cited by 60
Ayahuasca: A review of historical, pharmacological, and therapeutic aspects
Ruffell, S., Crosland‐Wood, M., Palmer, R., Netzband, N., Tsang, W., Weiss, B., Gandy, S., Cowley‐Court, T., Halman, A., McHerron, D., et al. (2023) · Psychiatry and Clinical Neurosciences Reports · doi:10.1002/pcn5.146 · Cited by 61
Adolescents are more sensitive than adults to acute behavioral and cognitive effects of THC
Murray, C. H., Huang, Z., Lee, R., & de Wit, H. (2022) · Neuropsychopharmacology · doi:10.1038/s41386-022-01281-w · Cited by 46
Classical and non-classical psychedelic drugs induce common network changes in human cortex
Dai, R., Larkin, T. E., Huang, Z., Tarnal, V., Picton, P., Vlisides, P. E., Janke, E., McKinney, A., Hudetz, A. G., Harris, R. E., et al. (2023) · NeuroImage · doi:10.1016/j.neuroimage.2023.120097 · Cited by 51
A synergistic workspace for human consciousness revealed by Integrated Information Decomposition
Luppi, A. I., Mediano, P. A. M., Rosas, F. E., Allanson, J. E., Pickard, J. D., Carhart-Harris, R. L., Williams, G. B., Craig, M. M., Finoia, P., Owen, A. M., et al. (2023) · eLife · doi:10.7554/elife.88173 · Cited by 120
Self-citationSerotonergic Psychedelics: Experimental Approaches for Assessing Mechanisms of Action
Canal, C. E. (2018) · Handbook of experimental pharmacology · doi:10.1007/164_2018_107 · Cited by 50
Effect of lysergic acid diethylamide (LSD) on reinforcement learning in humans
Kanen, J. W., Luo, Q., Kandroodi, M. R., Cardinal, R. N., Robbins, T. W., Nutt, D. J., Carhart-Harris, R. L., & den Ouden, H. E. M. (2022) · Psychological Medicine · doi:10.1017/s0033291722002963 · Cited by 47
Self-citationOrt, A., Smallridge, J. W., Sarasso, S., Casarotto, S., von Rotz, R., Casanova, A., Seifritz, E., Preller, K. H., Tononi, G., & Vollenweider, F. X. (2023) · iScience · doi:10.1016/j.isci.2023.106589 · Cited by 51
Drug Abuse and Psychosis: New Insights into Drug-induced Psychosis
Ham, S., Kim, T. K., Chung, S., & Im, H. (2017) · Experimental Neurobiology · doi:10.5607/en.2017.26.1.11 · Cited by 50
Bravermanová, A., Viktorinová, M., Tylš, F., Novák, T., Androvičová, R., Korčák, J., Horáček, J., Balíková, M., Griškova-Bulanova, I., Danielová, D., et al. (2018) · Psychopharmacology · doi:10.1007/s00213-017-4807-2 · Cited by 50
Prefrontal contributions to the stability and variability of thought and conscious experience
Zamani, A., Carhart-Harris, R. L., & Kalina Christoff, A. (2021) · Neuropsychopharmacology · doi:10.1038/s41386-021-01147-7 · Cited by 49
Self-citationMolecular and Functional Imaging Studies of Psychedelic Drug Action in Animals and Humans.
Cumming, P., Scheidegger, M., Dornbierer, D., Palner, M., Quednow, B. B., & Martin-Soelch, C. (2021) · Molecules · doi:10.3390/molecules26092451 · Cited by 43
Wang, B., Li, M., Haihambo, N. P., Qiu, Z., Sun, M., Guo, M., Zhao, X., & Han, C. (2024) · Journal of Affective Disorders · doi:10.1016/j.jad.2024.03.145 · Cited by 46
Seeing without self: Discovering new meaning with psychedelic-assisted psychotherapy
Fischman, L. G. (2019) · Neuropsychoanalysis · doi:10.1080/15294145.2019.1689528 · Cited by 52
Bridging the Gap? Altered Thalamocortical Connectivity in Psychotic and Psychedelic States
Avram, M., Rogg, H. V., Korda, A. I., Andreou, C., Müller, F., & Borgwardt, S. (2021) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2021.706017 · Cited by 49
Mindfulness meditation and psychedelics: potential synergies and commonalities
Holas, P., & Kamińska, J. (2023) · Pharmacological Reports · doi:10.1007/s43440-023-00551-8 · Cited by 43
“Such disruption is believed to be associated with the experience of ego dissolution [71].”
BackgroundOnofrj, M., Russo, M., Delli Pizzi, S., De Gregorio, D., Inserra, A., Gobbi, G., & Sensi, S. L. (2023) · Translational Psychiatry · doi:10.1038/s41398-023-02691-0 · Cited by 43
Tozzi, A. (2019) · Physics of Life Reviews · doi:10.1016/j.plrev.2018.12.004 · Cited by 44
Vejmola, Č., Tylš, F., Piorecká, V., Koudelka, V., Kadeřábek, L., Novák, T., & Páleníček, T. (2021) · Translational Psychiatry · doi:10.1038/s41398-021-01603-4 · Cited by 50
Lawn, T., Dipasquale, O., Vamvakas, A., Tsougos, I., Mehta, M. A., & Howard, M. A. (2022) · Psychopharmacology · doi:10.1007/s00213-022-06117-5 · Cited by 39
Neuroimaging in psychedelic drug development: past, present, and future
Wall, M. B., Harding, R., Zafar, R. R., Rabiner, E. A., Nutt, D., & Erritzøe, D. (2023) · Molecular Psychiatry · doi:10.1038/s41380-023-02271-0 · Cited by 43
Self-citationYu, Z., Burback, L., Winkler, O., Xu, L., Dennett, L., Vermetten, E. H. G. J. M., Greenshaw, A. J., Li, X., Milne, M., Wang, F., et al. (2024) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2024.1386321 · Cited by 49
Different hierarchical reconfigurations in the brain by psilocybin and escitalopram for depression
Deco, G., Perl, Y. S., Johnson, S., Bourke, N., Carhart-Harris, R. L., & Kringelbach, M. L. (2024) · Nature Mental Health · doi:10.1038/s44220-024-00298-y · Cited by 46
Self-citationSchipper, S., Nigam, K. B., Schmid, Y., Piechotta, V., Ljuslin, M., Beaussant, Y., Schwarzer, G., & Boehlke, C. S. (2024) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd015383.pub2 · Cited by 44
Michael, P., Luke, D. P., & Robinson, O. C. (2021) · Frontiers in Psychology · doi:10.3389/fpsyg.2021.720717 · Cited by 46
Eleftheriou, M. E., & Thomas, E. (2021) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2021.707057 · Cited by 39
“In the field of psychedelic neuroscience, reduced mPFC-PCC connectivity as well as DMN deactivation and disintegration have been demonstrated post-acutely after the administration of psilocybin, LSD and ayahuasca (45, 46, 57), while long-term ayahuasca users demonstrated thinning of the PCC (117).”
BackgroundMorgan, C. J. A., McAndrew, A., Stevens, T., Nutt, D., & Lawn, W. (2016) · Current Opinion in Behavioral Sciences · doi:10.1016/j.cobeha.2016.10.009 · Cited by 42
Self-citationAn ontology of psychedelic entity experiences in evolutionary psychology and neurophenomenology
Winkelman, M. (2018) · Journal of Psychedelic Studies · doi:10.1556/2054.2018.002 · Cited by 44
Suicide Has Many Faces, So Does Ketamine: a Narrative Review on Ketamine’s Antisuicidal Actions
Lengvenytė, A., Olié, É., & Courtet, P. (2019) · Current Psychiatry Reports · doi:10.1007/s11920-019-1108-y · Cited by 40
Smigielski, L., Kometer, M., Scheidegger, M., Stress, C., Preller, K. H., Koenig, T. W., & Vollenweider, F. X. (2020) · Human Brain Mapping · doi:10.1002/hbm.25174 · Cited by 43
Inserra, A., Gregorio, D. D., Rezai, T., López-Canul, M., Comai, S., & Gobbi, G. (2021) · Journal of Psychopharmacology · doi:10.1177/0269881121991569 · Cited by 41
Avram, M., Müller, F., Rogg, H. V., Korda, A. I., Andreou, C., Holze, F., Vizeli, P., Ley, L., Liechti, M. E., & Borgwardt, S. (2022) · Biological Psychiatry Cognitive Neuroscience and Neuroimaging · doi:10.1016/j.bpsc.2022.04.003 · Cited by 47
A Synergistic Workspace for Human Consciousness Revealed by Integrated Information DecompositionPreprint
Luppi, A. I., Mediano, P. A. M., Rosas, F. E., Allanson, J. E., Pickard, J. D., Carhart-Harris, R. L., Williams, G. B., Craig, M. M., Finoia, P., Owen, A. M., et al. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.11.25.398081 · Cited by 43
Self-citationThe effect of lysergic acid diethylamide (LSD) on whole-brain functional and effective connectivity
Bedford, P., Hauke, D. J., Wang, Z., Röth, V., Nagy-Huber, M., Holze, F., Ley, L., Vizeli, P., Liechti, M. E., Borgwardt, S., et al. (2023) · Neuropsychopharmacology · doi:10.1038/s41386-023-01574-8 · Cited by 42
From relaxed beliefs under psychedelics (REBUS) to revised beliefs after psychedelics (REBAS)
Zeifman, R. J., Spriggs, M. J., Kettner, H., Lyons, T., Rosas, F. E., Mediano, P. A. M., Erritzøe, D., & Carhart-Harris, R. L. (2025) · Scientific Reports · doi:10.1038/s41598-023-28111-3 · Cited by 62
Self-citationAdams, W. K., Barkus, C., Ferland, J. N., Sharp, T., & Winstanley, C. A. (2017) · Psychopharmacology · doi:10.1007/s00213-017-4696-4 · Cited by 41
Psychedelic treatment of functional neurological disorder: a systematic review
Butler, M., Seynaeve, M., Nicholson, T. R., Pick, S., Kanaan, R., Lees, A. J., Young, A. H., & Rucker, J. (2020) · Therapeutic Advances in Psychopharmacology · doi:10.1177/2045125320912125 · Cited by 39
Volgin, A. D., Yakovlev, O. A., Demin, K. A., Alekseeva, P. A., Kyzar, E. J., Collins, C. J., Nichols, D. E., & Kalueff, A. V. (2018) · ACS Chemical Neuroscience · doi:10.1021/acschemneuro.8b00433 · Cited by 42
Self-citationMüller, F., Holze, F., Dolder, P. C., Ley, L., Vizeli, P., Soltermann, A., Liechti, M. E., & Borgwardt, S. (2020) · Neuropsychopharmacology · doi:10.1038/s41386-020-00906-2 · Cited by 39
Zoubi, O. A., Misaki, M., Bodurka, J., Kuplicki, R., Wohlrab, C., Schoenhals, W. A., Refai, H. H., Khalsa, S. S., Stein, M. B., Paulus, M. P., et al. (2021) · Human Brain Mapping · doi:10.1002/hbm.25429 · Cited by 41
Catalysts for change: the cellular neurobiology of psychedelics
Banks, M. I., Zahid, Z., Jones, N., Sultan, Z. W., & Wenthur, C. J. (2021) · Molecular Biology of the Cell · doi:10.1091/mbc.e20-05-0340 · Cited by 45
Brys, I., Barrientos, S. A., Ward, J. E., Wallander, J., Petersson, P., & Halje, P. (2023) · Communications Biology · doi:10.1038/s42003-023-05093-6 · Cited by 37
The entropic tongue: Disorganization of natural language under LSD.
Sanz, C., Pallavicini, C., Carrillo, F., Zamberlan, F., Sigman, M., Mota, N., Copelli, M., Ribeiro, S., Nutt, D., Carhart-Harris, R. L., et al. (2020) · Consciousness and Cognition · doi:10.1016/j.concog.2020.103070 · Cited by 31
Self-citationLosing the Self in Near-Death Experiences: The Experience of Ego-Dissolution
Martial, C., Fontaine, G. P., Gosseries, O., Carhart-Harris, R. L., Timmermann, C., Laureys, S., & Cassol, H. (2021) · Brain Sciences · doi:10.3390/brainsci11070929 · Cited by 41
Self-citationThe History of Psychedelics in Medicine
Sessa, B. (2016) · Springer eBooks · doi:10.1007/978-3-642-55214-4_96-1 · Cited by 44
Self-citationIncreased sensitivity to strong perturbations in a whole-brain model of LSD
Jobst, B., Atasoy, S., Ponce‐Alvarez, A., Sanjuán, A., Roseman, L., Kaelen, M., Carhart-Harris, R. L., Kringelbach, M. L., & Deco, G. (2021) · NeuroImage · doi:10.1016/j.neuroimage.2021.117809 · Cited by 36
Self-citationDourron, H. M., Strauss, C. K., & Hendricks, P. S. (2022) · Pharmacological Reviews · doi:10.1124/pharmrev.121.000514 · Cited by 35
Psilocybin and Other Classic Psychedelics in Depression
Nutt, D., Peill, J. M., Weiss, B., Godfrey, K., Carhart-Harris, R. L., & Erritzøe, D. (2023) · Current topics in behavioral neurosciences · doi:10.1007/7854_2023_451 · Cited by 39
Self-citationMurray, C. H., Frohlich, J., Haggarty, C. J., Tare, I., Lee, R., & de Wit, H. (2024) · Neuropsychopharmacology · doi:10.1038/s41386-024-01809-2 · Cited by 36
Egger, K., Aicher, H., Cumming, P. D., & Scheidegger, M. (2024) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-024-05353-6 · Cited by 37
Synchronization in Functional Networks of the Human Brain
Hövel, P., Viol, A., Loske, P., Merfort, L., & Vuksanović, V. (2018) · Journal of Nonlinear Science · doi:10.1007/s00332-018-9505-7 · Cited by 37
Dementia-related psychosis and the potential role for pimavanserin
Cummings, J. L., Devanand, D. P., & Stahl, S. M. (2020) · CNS Spectrums · doi:10.1017/s1092852920001765 · Cited by 35
Trends in the Top-Cited Articles on Classic Psychedelics
Lawrence, D. W., Sharma, B., Griffiths, R. R., & Carhart-Harris, R. (2021) · Journal of Psychoactive Drugs · doi:10.1080/02791072.2021.1874573 · Cited by 35
Self-citationCastelhano, J., Lima, G., Teixeira, M., Soares, C., Pais, M. L., & Castelo-Branco, M. S. (2021) · Frontiers in Pharmacology · doi:10.3389/fphar.2021.739053 · Cited by 41
Liechti, M. E., & Holze, F. (2021) · Current topics in behavioral neurosciences · doi:10.1007/7854_2021_270 · Cited by 37
Kurtz, J. S., Patel, N., Gendreau, J. L., Yang, C., Brown, N. J., Bui, N., Picton, B., Harris, M., Hatter, M. J., Beyer, R. S., et al. (2022) · Cureus · doi:10.7759/cureus.29167 · Cited by 40
Müller, F., Liechti, M. E., Lang, U. E., & Borgwardt, S. (2018) · Progress in Brain Research · doi:10.1016/bs.pbr.2018.08.004 · Cited by 31
How do serotonergic psychedelics treat depression: The potential role of neuroplasticity
Artin, H., Zisook, S., & Ramanathan, D. (2021) · World Journal of Psychiatry · doi:10.5498/wjp.v11.i6.201 · Cited by 33
Exploring mechanisms of psychedelic action using neuroimaging
Erritzøe, D., Timmermann, C., Godfrey, K. E. M., Castro-Rodrigues, P., Peill, J. M., Carhart-Harris, R. L., Nutt, D., & Wall, M. B. (2024) · Nature Mental Health · doi:10.1038/s44220-023-00172-3 · Cited by 37
Self-citationBreathwork-induced psychedelic experiences modulate neural dynamics
Lewis-Healey, E., Tagliazucchi, E., Canales‐Johnson, A., & Bekinschtein, T. A. (2024) · Cerebral Cortex · doi:10.1093/cercor/bhae347 · Cited by 36
Self-citationHallucinations on demand: the utility of experimentally induced phenomena in hallucination research
Rogers, S., Keogh, R., & Pearson, J. (2020) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.2020.0233 · Cited by 33
Filippo, R. D., Rost, B. R., Stumpf, A., Cooper, C., Tukker, J. J., Harms, C., Beed, P. S., & Schmitz, D. (2021) · eLife · doi:10.7554/elife.66960 · Cited by 34
Zarkali, A., Luppi, A. I., Stamatakis, E. A., Reeves, S., McColgan, P., Leyland, L., Lees, A. J., & Weil, R. S. (2022) · Communications Biology · doi:10.1038/s42003-022-03903-x · Cited by 36
Not with a “zap” but with a “beep”: Measuring the origins of perinatal experience
Frohlich, J., Bayne, T., Crone, J. S., Dallavecchia, A., Kirkeby-Hinrup, A., Mediano, P. A. M., Moser, J., Talar, K., Gharabaghi, A., & Preissl, H. T. (2023) · NeuroImage · doi:10.1016/j.neuroimage.2023.120057 · Cited by 33
Weiss, B., Roseman, L., Giribaldi, B., Nutt, D., Carhart-Harris, R. L., & Erritzøe, D. (2024) · International Journal of Mental Health and Addiction · doi:10.1007/s11469-024-01253-9 · Cited by 41
Self-citationConscious dance: Perceived benefits and psychological well-being of participants
Laird, K. T., Vergeer, I., Hennelly, S. E., & Siddarth, P. (2021) · Complementary Therapies in Clinical Practice · doi:10.1016/j.ctcp.2021.101440 · Cited by 40
LSD-induced increase of Ising temperature and algorithmic complexity of brain dynamics
Ruffini, G., Damiani, G., Lozano‐Soldevilla, D., Deco, N., Rosas, F. E., Kiani, N. A., Ponce‐Alvarez, A., Kringelbach, M. L., Carhart-Harris, R. L., & Deco, G. (2023) · PLoS Computational Biology · doi:10.1371/journal.pcbi.1010811 · Cited by 32
Self-citationSingleton, S. P., Luppi, A. I., Carhart-Harris, R. L., Cruzat, J., Roseman, L., Nutt, D. J., Deco, G., Kringelbach, M. L., Stamatakis, E. A., & Kuceyeski, A. F. (2021) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2021.05.14.444193 · Cited by 30
Self-citationMind the Psychedelic Hype: Characterizing the Risks and Benefits of Psychedelics for Depression
Meling, D., Ehrenkranz, R. C., Nayak, S. M., Aicher, H., Funk, X., van Elk, M., Graziosi, M., Bauer, P. R., Scheidegger, M., & Yaden, D. B. (2024) · Psychoactives · doi:10.3390/psychoactives3020014 · Cited by 35
Dolder, P. C., Liechti, M. E., & Rentsch, K. (2017) · Journal of Clinical Laboratory Analysis · doi:10.1002/jcla.22265 · Cited by 31
The renaissance in psychedelic research: What do preclinical models have to offer
Murnane, K. S. (2018) · Progress in brain research · doi:10.1016/bs.pbr.2018.08.003 · Cited by 35
The Altered States Database: Psychometric data from a systematic literature review
Prugger, J., Derdiyok, E., Dinkelacker, J., Costines, C., & Schmidt, T. T. (2022) · Scientific Data · doi:10.1038/s41597-022-01822-4 · Cited by 36
Keppler, J. (2018) · Frontiers in Psychology · doi:10.3389/fpsyg.2018.01346 · Cited by 30
Psychedelic Cognition—The Unreached Frontier of Psychedelic Science
Bălăeţ, M. (2022) · Frontiers in Neuroscience · doi:10.3389/fnins.2022.832375 · Cited by 34
The evolution of N, N-Dimethyltryptamine: from metabolic pathways to brain connectivity
Gupta, S., Bhatnagar, R. K., Gupta, D., Maharaj Kumari, K., & Chopra, A. (2025) · Psychopharmacology · doi:10.1007/s00213-025-06777-z · Cited by 32
Fox, K. C. R., Girn, M., Parro, C., & Kalina Christoff, A. (2018) · Cambridge University Press eBooks · doi:10.1017/9781316556238.007 · Cited by 30
Psychedelics and dissociative substances
WINSTOCK, A. R., & Rucker, J. (2020) · doi:10.1093/med/9780198713005.003.0054 · Cited by 29
Trautwein, F., Schweitzer, Y., Dor‐Ziderman, Y., Nave, O., Ataria, Y., Fulder, S. J., & Berkovich‐Ohana, A. (2024) · Journal of Neuroscience · doi:10.1523/jneurosci.1182-23.2024 · Cited by 34
Avram, M., Fortea, L., Wollner, L., Coenen, R., Korda, A. I., Rogg, H. V., Holze, F., Vizeli, P., Ley, L., Raduà, J., et al. (2024) · Molecular Psychiatry · doi:10.1038/s41380-024-02734-y · Cited by 32
Human brain changes after first psilocybin use
Lyons, T., Spriggs, M., Kerkelä, L., Rosas, F. E., Roseman, L., Mediano, P. A. M., Timmermann, C., Oestreich, L., Pagni, B. A., Zeifman, R. J., et al. (2026) · Nature Communications · doi:10.1038/s41467-026-71962-3 · Cited by 30
Self-citationPerception is in the details: A predictive coding account of the psychedelic phenomenon
Pink-Hashkes, S., van Rooij, I. J. E. I., & Kwisthout, J. (2017) · eScholarship (California Digital Library) · Cited by 28
Psychedelics and hypnosis: Commonalities and therapeutic implications
Lemercier, C. E., & Terhune, D. B. (2018) · Journal of Psychopharmacology · doi:10.1177/0269881118780714 · Cited by 32
Le, G. H., Wong, S., Badulescu, S., Au, H., Di Vincenzo, J. D., Gill, H., Phan, L., Rhee, T. G., Ho, R., Teopiz, K. M., et al. (2024) · Journal of Affective Disorders · doi:10.1016/j.jad.2024.03.165 · Cited by 30
A role for the serotonin 2A receptor in the expansion and functioning of human transmodal cortex
Luppi, A. I., Girn, M., Rosas, F. E., Timmermann, C., Roseman, L., Erritzøe, D., Nutt, D., Stamatakis, E. A., Spreng, R. N., Xing, L., et al. (2023) · Brain · doi:10.1093/brain/awad311 · Cited by 31
Self-citationLSD-induced changes in the functional connectivity of distinct thalamic nuclei
Pizzi, S. D., Chiacchiaretta, P., Sestieri, C., Ferretti, A., Tullo, M. G., Penna, S. D., Martinotti, G., ONOFRJ, M. C., Roseman, L., Timmermann, C., et al. (2023) · NeuroImage · doi:10.1016/j.neuroimage.2023.120414 · Cited by 29
Self-citationA Comprehensive Review of the Current Status of the Cellular Neurobiology of Psychedelics
Banushi, B., & Polito, V. (2023) · Biology · doi:10.3390/biology12111380 · Cited by 33
EASTERN MYSTICISM AND TIMOTHY LEARY: HUMAN BEYOND THE CONVENTIONAL REALITY
Danylova, T. V. (2017) · Anthropological Measurements of Philosophical Research · doi:10.15802/ampr.v0i11.105498 · Cited by 28
Winne, J., Ciralli, B., Malfatti, T., Brisa, E., Doerl, J. G., Nogueira, I., Leão, K. E., & Leão, R. N. (2020) · Experimental Neurology · doi:10.1016/j.expneurol.2020.113175 · Cited by 27
Dose-response relationships of LSD-induced subjective experiences in humans
Hirschfeld, T., Prugger, J., Majić, T., & Schmidt, T. T. (2023) · Neuropsychopharmacology · doi:10.1038/s41386-023-01588-2 · Cited by 29
Buchborn, T., Kettner, H., Kärtner, L., & Meinhardt, M. W. (2023) · Frontiers in Neuroscience · doi:10.3389/fnins.2023.1232459 · Cited by 30
A Computational Account of the Development and Evolution of Psychotic Symptoms
Powers, A. R., Angelos, P. A., Bond, A., Farina, E., Fredericks, C. A., Gandhi, J., Greenwald, M. S., Hernández-Busot, G., Hosein, G. X., Kelley, M., et al. (2024) · Biological Psychiatry · doi:10.1016/j.biopsych.2024.08.026 · Cited by 29
Hypnotic suggestion produces mystical-type experiences in the laboratory: A demonstration proof.
Lynn, S. J., & Evans, J. V. (2017) · Psychology of Consciousness Theory Research and Practice · doi:10.1037/cns0000105 · Cited by 28
Self-citationTripping over the other: Could psychedelics increase empathy?
Blatchford, E., Bright, S. J., & Engel, L. B. (2020) · Journal of Evolutionary Psychology · doi:10.1556/2054.2020.00136 · Cited by 30
Effects of classic psychedelic drugs on turbulent signatures in brain dynamics
Cruzat, J., Perl, Y. S., Escrichs, A., Vohryzek, J., Timmermann, C., Roseman, L., Luppi, A. I., Ibáñez, A. M., Nutt, D. J., Carhart-Harris, R. L., et al. (2022) · Network Neuroscience · doi:10.1162/netn_a_00250 · Cited by 26
Self-citation
Metadata
- Authors
- Carhart-Harris, R. L., Muthukumaraswamy, S., Roseman, L., Kaelen, M., Droog, W., Murphy, K., Tagliazucchi, E., Schenberg, E. E., Nest, T., Orban, C., Leech, R., Williams, L. T., Williams, T. M., Bolstridge, M., Sessa, B., McGonigle, J., Sereno, M. I., Nichols, D., Hellyer, P. J., Hobden, P., Evans, J., Singh, K. D., Wise, R. G., Curran, H. V., Feilding, A., & Nutt, D. J.
- Affiliations
- Imperial College London (GB)
- University of Auckland (NZ)
- Cardiff University (GB)
- Goethe University Frankfurt (DE)
- McGill University (CA)
- Centre for Neuropsychopharmacology, Department of Medicine, Imperial College London, W12 0NN, London, United Kingdom;
- Department of Psychiatry, University of Bristol, BS8 2BN, Bristol, United Kingdom;
- University College London (GB)
- University of North Carolina at Chapel Hill (US)
- Beckley Foundation (GB)
- ORCID
- Carhart-Harris, Robin L.
- Muthukumaraswamy, Suresh
- Roseman, Leor
- Kaelen, Mendel
- Droog, Wouter
- Murphy, Kevin
- Tagliazucchi, Enzo
- Schenberg, Eduardo E.
- Leech, Robert
- Sessa, Ben
- McGonigle, John
- Sereno, Martin I.
- Nichols, David
- Hellyer, Peter J.
- Evans, John
- Singh, Krish D.
- Wise, Richard G.
- Curran, H. Valerie
- Feilding, Amanda
- Nutt, David J.
- Venue
- Proceedings of the National Academy of Sciences
- Publisher
- National Academy of Sciences
- Published
- 2016-04-11
- Volume
- 113
- Issue
- 17
- Pages
- 4853-4858
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- PMC
- PMC4855588
- OpenAlex
- W2336389811
- Cited by
- 859
- References
- 47
- Citations by year
- 2026: 79 · 2025: 85 · 2024: 110 · 2023: 112 · 2022: 83 · 2021: 85 · 2020: 67 · 2019: 70 · 2018: 74 · 2017: 64 · 2016: 29
- FWCI
- 105.63
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Proceedings of the National Academy of Sciences (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- ORCA Online Research @Cardiff (Cardiff University) (acceptedVersion)
- Research Bank (Australian Catholic University) (submittedVersion)
- BIROn (Birkbeck, University of London) (submittedVersion)
- UCL Discovery (University College London) (submittedVersion)
- eScholarship (California Digital Library) (submittedVersion)
- LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Científicas) (submittedVersion, other-oa)
- Spiral (Imperial College London) (submittedVersion, other-oa)
- Funders
- Wellcome Trust (WT090199, 200804/Z/16/Z)
- Topics
- Social Sciences › Psychology › Clinical Psychology › Psychedelics and Drug Studies
- Life Sciences › Neuroscience › Cognitive Neuroscience › Hallucinations in medical conditions
- Social Sciences › Psychology › Social Psychology › Paranormal Experiences and Beliefs
- Keywords
- lysergic acid diethylamide, LSD, psychedelics, visual hallucinations, ego dissolution, visual cortex, primary visual cortex, cerebral blood flow, alpha power, functional connectivity, parahippocampal cortex, retrosplenial cortex, consciousness, resting-state brain activity
- MeSH terms
- Brain, Brain Mapping, Cerebrovascular Circulation, Consciousness, Hallucinations, Hallucinogens, Humans, Lysergic Acid Diethylamide, Magnetic Resonance Imaging, Nerve Net, Synaptic Transmission, Oxygen, Spin Labels, Magnetoencephalography, Receptor, Serotonin, 5-HT2A, Serotonin 5-HT2 Receptor Agonists, Connectome, Multimodal Imaging
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
