The DOI matches its Crossref record; 9 of the 9 references it cites were found in a registry or an index.
Extracellular vesicles and viruses: Are they close relatives?
Open accessAbstract
Extracellular vesicles (EVs) released by various cells are small phospholipid membrane-enclosed entities that can carry miRNA. They are now central to research in many fields of biology because they seem to constitute a new system of cell–cell communication. Physical and chemical characteristics of many EVs, as well as their biogenesis pathways, resemble those of retroviruses. Moreover, EVs generated by virus-infected cells can incorporate viral proteins and fragments of viral RNA, being thus indistinguishable from defective (noninfectious) retroviruses. EVs, depending on the proteins and genetic material incorporated in them, play a significant role in viral infection, both facilitating and suppressing it. Deciphering the mechanisms of EV-cell interactions may facilitate the design of EVs that inhibit viral infection and can be used as vehicles for targeted drug delivery.
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Cited by
The biology , function , and biomedical applications of exosomes
Kalluri, R., & LeBleu, V. S. (2020) · Science · doi:10.1126/science.aau6977 · Cited by 10,770
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Extracellular vesicles as a next-generation drug delivery platform
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RNA delivery by extracellular vesicles in mammalian cells and its applications
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Extracellular Vesicles and Nanoparticles: Emerging Complexities
Jeppesen, D. K., Zhang, Q., Franklin, J. L., & Coffey, R. J. (2023) · Trends in Cell Biology · doi:10.1016/j.tcb.2023.01.002 · Cited by 705
Metadata
- Authors
- Nolte-‘t Hoen, E., Cremer, T., Gallo, R. C., & Margolis, L. B.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 2016-07-18
- Volume
- 113
- Issue
- 33
- Pages
- 9155-9161
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W2495898729
- Cited by
- 494
- References
- 9
- FWCI
- 17.00
- Type
- journal article
- Language
- en
- Open access
- green
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- Nolte-‘t Hoen, E., Cremer, T., Gallo, R. C., & Margolis, L. B. (2016). Extracellular vesicles and viruses: Are they close relatives? Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.1605146113
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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