The DOI matches its Crossref record; 11 of the 11 references it cites were found in a registry or an index.
Knee osteoarthritis has doubled in prevalence since the mid-20th century
Open accessAbstract
Significance: Knee osteoarthritis is a highly prevalent, disabling joint disease with causes that remain poorly understood but are commonly attributed to aging and obesity. To gain insight into the etiology of knee osteoarthritis, this study traces long-term trends in the disease in the United States using large skeletal samples spanning from prehistoric times to the present. We show that knee osteoarthritis long existed at low frequencies, but since the mid-20th century, the disease has doubled in prevalence. Our analyses contradict the view that the recent surge in knee osteoarthritis occurred simply because people live longer and are more commonly obese. Instead, our results highlight the need to study additional, likely preventable risk factors that have become ubiquitous within the last half-century.
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Cites
The Measurement of Observer Agreement for Categorical Data
Landis, J. R., & Koch, G. G. (1977) · Biometrics · doi:10.2307/2529310 · Cited by 81,148
Vos, T., Flaxman, A. D., Naghavi, M., Lozano, R., Michaud, C., Ezzati, M., Shibuya, K., Salomon, J. A., Abdalla, S., Aboyans, V., et al. (2012) · The Lancet · doi:10.1016/s0140-6736(12)61729-2 · Cited by 8,291
Self-citationMatching Methods for Causal Inference: A Review and a Look Forward
Stuart, E. A. (2010) · Statistical Science · doi:10.1214/09-sts313 · Cited by 5,478
MatchIt : Nonparametric Preprocessing for Parametric Causal Inference
Ho, D. E., Imai, K., King, G., & Stuart, E. A. (2011) · Journal of Statistical Software · doi:10.18637/jss.v042.i08 · Cited by 4,385
The State of US Health, 1990-2010: Burden of Diseases, Injuries, and Risk Factors
Murray, C. J. L. (2013) · JAMA · doi:10.1001/jama.2013.13805 · Cited by 2,438 · cited 15×
“Here, we investigate long-term trends in knee OA prevalence in the United States and evaluate the effects of longevity and Significance Knee osteoarthritis is a highly prevalent, disabling joint disease with causes that remain poorly understood but are commonly attributed to aging and obesity.”
BackgroundInfluentialA newly developed visual method of sexing the os pubis
Phenice, T. W. (1969) · American Journal of Physical Anthropology · doi:10.1002/ajpa.1330300214 · Cited by 1,625
Church, T. S., Thomas, D. M., Tudor-Locke, C., Katzmarzyk, P. T., Earnest, C. P., Rodarte, R. Q., Martin, C. K., Blair, S. N., & Bouchard, C. (2011) · PLoS ONE · doi:10.1371/journal.pone.0019657 · Cited by 1,294
The role of exercise and PGC1α in inflammation and chronic disease
Handschin, C., & Spiegelman, B. M. (2008) · Nature · doi:10.1038/nature07206 · Cited by 1,083
Counterfactuals and Causal Inference: Methods and Principles for Social Research
Morgan, S. L., & Winship, C. (2014) · Cambridge University Press · doi:10.1017/cbo9781107587991 · Cited by 1,037
The Effects of Diet on Inflammation
Giugliano, D., Ceriello, A., & Esposito, K. (2006) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2006.03.052 · Cited by 842
Osteoarthritis as a disease of mechanics
Felson, D. T. (2013) · Osteoarthritis and Cartilage · doi:10.1016/j.joca.2012.09.012 · Cited by 676
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Cited by
Osteoarthritis: pathogenic signaling pathways and therapeutic targets
Yao, Q., Wu, X., Tao, C., Gong, W., Chen, M., Qu, M., Zhong, Y., He, T., Chen, S., & Xiao, G. (2023) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-023-01330-w · Cited by 1,194
Wallace, T. C., Bailey, R. L., Blumberg, J. B., Burton-Freeman, B., Chen, C.-Y. O., Crowe-White, K. M., Drewnowski, A., Hooshmand, S., Johnson, E., Lewis, R., et al. (2020) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2019.1632258 · Cited by 638
Garza, J. R., Campbell, R. E., Tjoumakaris, F. P., Freedman, K. B., Miller, L. S., Santa Maria, D., & Tucker, B. S. (2020) · The American Journal of Sports Medicine · doi:10.1177/0363546519899923 · Cited by 200
Potential efficacy of dendritic cell immunomodulation in the treatment of osteoarthritis
Alahdal, M., Zhang, H., Huang, R., Sun, W., Deng, Z., Duan, L., Ouyang, H., & Wang, D. (2021) · Rheumatology · doi:10.1093/rheumatology/keaa745 · Cited by 50
Ding, W., Xu, Y.-Q., Zhang, Y., Li, A.-X., Qiu, X., Wen, H.-J., & Tan, H.-B. (2021) · CARTILAGE · doi:10.1177/1947603520942947 · Cited by 32
Metadata
- Authors
- Wallace, I. J., Worthington, S., Felson, D. T., Jurmain, R. D., Wren, K. T., Maijanen, H., Woods, R. J., & Lieberman, D. E.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 2017-08-14
- Volume
- 114
- Issue
- 35
- Pages
- 9332-9336
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W2747777164
- Cited by
- 1,071
- References
- 11
- FWCI
- 69.59
- Type
- journal article
- Language
- en
- Open access
- bronze
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
