The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
The antimicrobial peptide ZY4 combats multidrug-resistant Pseudomonas aeruginosa and Acinetobacter baumannii infection
Open accessAbstract
Significance: This work showed that a designed cyclic peptide ZY4 exhibits excellent activity against Pseudomonas aeruginosa and Acinetobacter baumannii . ZY4 not only inhibits planktonic growth and biofilm formation but also kills persister cells by permeabilizing bacterial membrane. ZY4 showed low propensity to induce resistance, high stability in vivo, and therapeutic potentials in MDR P. aeruginosa – and A. baumannii –induced infection. The present study provides a promising drug candidate in the war against multidrug resistance.
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Cites
Defensins: antimicrobial peptides of innate immunity
Ganz, T. (2003) · Nature Reviews Immunology · doi:10.1038/nri1180 · Cited by 3,066
The antimicrobial peptide SAAP-148 combats drug-resistant bacteria and biofilms
de Breij, A., Riool, M., Cordfunke, R. A., Malanovic, N., de Boer, L., Koning, R. I., Ravensbergen, E., Franken, M., van der Heijde, T., Boekema, B. K., et al. (2018) · Science Translational Medicine · doi:10.1126/scitranslmed.aan4044 · Cited by 555
Fauvart, M., De Groote, V. N., & Michiels, J. (2011) · Journal of Medical Microbiology · doi:10.1099/jmm.0.030932-0 · Cited by 425
Cited by
Antimicrobial peptides for combating drug-resistant bacterial infections
Xuan, J., Feng, W., Wang, J., Wang, R., Zhang, B., Bo, L., Chen, Z.-S., Yang, H., & Sun, L. (2023) · Drug Resistance Updates · doi:10.1016/j.drup.2023.100954 · Cited by 665
Balasubramaniam, B., Prateek, Ranjan, S., Saraf, M., Kar, P., Singh, S. P., Thakur, V. K., Singh, A., & Gupta, R. K. (2021) · ACS Pharmacology & Translational Science · doi:10.1021/acsptsci.0c00174 · Cited by 285
Antifungal Activity of ToAP2D Peptide Against Sporothrix globosa
Yan, T., Li, F., Li, J., & Chen, F. (2021) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2021.761518 · Cited by 16
Metadata
- Authors
- Mwangi, J., Yin, Y., Wang, G., Yang, M., Li, Y., Zhang, Z., & Lai, R.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 2019-12-16
- Volume
- 116
- Issue
- 52
- Pages
- 26516-26522
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W2994634742
- Cited by
- 286
- References
- 3
- FWCI
- 21.94
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- Mwangi, J., Yin, Y., Wang, G., Yang, M., Li, Y., Zhang, Z., & Lai, R. (2019). The antimicrobial peptide ZY4 combats multidrug-resistant Pseudomonas aeruginosa and Acinetobacter baumannii infection. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.1909585117
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