Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor

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Protection against Fatal Sindbis Virus Encephalitis by Beclin, a Novel Bcl-2-Interacting Protein

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Autophagy in Human Embryonic Stem Cells

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Autophagy in Toxicology: Cause or Consequence?

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Heme Oxygenase-1 Promotes Survival of Renal Cancer Cells through Modulation of Apoptosis- and Autophagy-regulating Molecules

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Autophagy regulation in preeclampsia: Pros and cons

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Targeting autophagy in breast cancer

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The Evolving, Multifaceted Roles of Autophagy in Cancer

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Distinct roles of autophagy-dependent and -independent functions of FIP200 revealed by generation and analysis of a mutant knock-in mouse modelPreprint

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Nrbf2 Protein Suppresses Autophagy by Modulating Atg14L Protein-containing Beclin 1-Vps34 Complex Architecture and Reducing Intracellular Phosphatidylinositol-3 Phosphate Levels

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Hepatitis C Virus and Cellular Stress Response: Implications to Molecular Pathogenesis of Liver Diseases

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Autophagy, cancer and angiogenesis: where is the link?

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Decreased expression of autophagic beclin 1 protein in idiopathic pulmonary fibrosis fibroblasts

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p53 and p21 Determine the Sensitivity of Noscapine-Induced Apoptosis in Colon Cancer Cells

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Autophagic cell death induced by 5-FU in Bax or PUMA deficient human colon cancer cell

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The Paradox of p53: What, How, and Why?Preprint

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Autophagy Paradox of Cancer: Role, Regulation, and Duality

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GOLGA2/GM130, cis-Golgi Matrix Protein, is a Novel Target of Anticancer Gene Therapy

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Initiation of Apoptosis and Autophagy by Photodynamic Therapy

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Autophagy-active beclin-1 correlates with favourable clinical outcome in non-Hodgkin lymphomas

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A Matter of Life or Death (or Both): Understanding Autophagy in Cancer

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Autophagy regulation and its role in gastric cancer and colorectal cancer

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Oxidative stress activates the TRPM2-Ca 2+ -CaMKII-ROS signaling loop to induce cell death in cancer cells

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Curcumin, a Multifaceted Hormetic Agent, Mediates an Intricate Crosstalk between Mitochondrial Turnover, Autophagy, and Apoptosis

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The role of autophagy in cancer: from molecular mechanism to therapeutic window

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HDAC Family Members Intertwined in the Regulation of Autophagy: A Druggable Vulnerability in Aggressive Tumor Entities

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ROS, autophagy, mitochondria and cancer: Ras, the hidden master?

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Transient receptor potential vanilloid 1 activation induces autophagy in thymocytes through ROS-regulated AMPK and Atg4C pathways

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Controlling cell growth and survival through regulated nutrient transporter expression

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Autophagy and mitophagy in the myocardium: therapeutic potential and concerns

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Inhibition of isoprenylcysteine carboxylmethyltransferase induces autophagic-dependent apoptosis and impairs tumor growth

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The Multifaceted Roles of Autophagy in Tumors—Implications for Breast Cancer

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Beclin 1 regulates growth factor receptor signaling in breast cancer

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BRCA1 Loss Preexisting in Small Subpopulations of Prostate Cancer Is Associated with Advanced Disease and Metastatic Spread to Lymph Nodes and Peripheral Blood

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Viral interactions with macroautophagy: A double-edged sword

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Targeting the Interplay of Autophagy and ROS for Cancer Therapy: An Updated Overview on Phytochemicals

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ISG20L1 is a p53 family target gene that modulates genotoxic stress-induced autophagy

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Challenges and Therapeutic Opportunities of Autophagy in Cancer Therapy

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Understanding the Role of Autophagy in Cancer Formation and Progression Is a Real Opportunity to Treat and Cure Human Cancers

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Autophagy, Oxidative Stress and Cancer Development

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Melatonin induces autophagy via an mTOR ‐dependent pathway and enhances clearance of mutant‐TGFBIp

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HAMLET (human α‐lactalbumin made lethal to tumor cells) triggers autophagic tumor cell death

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Cyclin D1 Activity Regulates Autophagy and Senescence in the Mammary Epithelium

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The Multifaceted Roles of Autophagy in Flavivirus-Host Interactions

Ke, P. (2018) · International Journal of Molecular Sciences · doi:10.3390/ijms19123940 · Cited by 78

Membrane trafficking and autophagy in pathogen-triggered cell death and immunity

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Aflatoxin B1 impairs leydig cells through inhibiting AMPK/mTOR-mediated autophagy flux pathway

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The effect of ammonia exposure on energy metabolism and mitochondrial dynamic proteins in chicken thymus: Through oxidative stress, apoptosis, and autophagy

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Regulation of the Death-Associated Protein Kinase 1 Expression and Autophagy via ATF6 Requires Apoptosis Signal-Regulating Kinase 1

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Beclin1 haploinsufficiency rescues low ambient temperature-induced cardiac remodeling and contractile dysfunction through inhibition of ferroptosis and mitochondrial injury

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Down-regulation of Beclin1 promotes direct cardiac reprogramming

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Autophagy in stem and progenitor cells

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Autophagy inhibition contributes to radiation sensitization of esophageal squamous carcinoma cells

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Beclin 1-mediated macroautophagy involves regulation of caspase-9 expression in cervical cancer HeLa cells

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Developmental regulation of MURF E3 ubiquitin ligases in skeletal muscle

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Prognostic Significance of Autophagy-Related Protein Expression in Resected Pancreatic Ductal Adenocarcinoma

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Using Functional Signature Ontology (FUSION) to Identify Mechanisms of Action for Natural Products

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Disruption of a Sirt1-Dependent Autophagy Checkpoint in the Prostate Results in Prostatic Intraepithelial Neoplasia Lesion Formation

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Autophagy-Inducing Protein Beclin-1 in Dendritic Cells Regulates CD4 T Cell Responses and Disease Severity during Respiratory Syncytial Virus Infection

Reed, M., Morris, S. B., Jang, S., Mukherjee, S., Yue, Z., & Lukacs, N. W. (2013) · The Journal of Immunology · doi:10.4049/jimmunol.1300477 · Cited by 72

Autophagy, a double-edged sword in anti-angiogenesis therapy

Liu, J., Fan, L., Wang, H., & Sun, G. (2015) · Medical Oncology · doi:10.1007/s12032-015-0721-9 · Cited by 72

Elevated p62/SQSTM1 determines the fate of autophagy-deficient neural stem cells by increasing superoxide

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Crosstalk Between ROS and Autophagy in Tumorigenesis: Understanding the Multifaceted Paradox

Hasan, A., Rizvi, S. F., Parveen, S., Pathak, N., Nazir, A., & Mir, S. S. (2022) · Frontiers in Oncology · doi:10.3389/fonc.2022.852424 · Cited by 77

Beclin 1 Expression in Ovarian Tissues and Its Effects on Ovarian Cancer Prognosis

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Autophagy Contributes to the Death/Survival Balance in Cancer PhotoDynamic Therapy

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Obscurin and KCTD6 regulate cullin-dependent small ankyrin-1 (sAnk1.5) protein turnover

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MicroRNA-146a Induced by Hypoxia Promotes Chondrocyte Autophagy through Bcl-2

Zhang, F., Wang, J., Chu, J., Yang, C., Xiao, H., Zhao, C., Sun, Z., Gao, X., Chen, G., Han, Z., et al. (2015) · Cellular Physiology and Biochemistry · doi:10.1159/000438513 · Cited by 68

The Role of Autophagy in Liver Cancer: Crosstalk in Signaling Pathways and Potential Therapeutic Targets

Cui, J., Shen, H., & Lim, L. H. K. (2020) · Pharmaceuticals · doi:10.3390/ph13120432 · Cited by 72

Autophagic Degradation of Mitochondria in White Adipose Tissue Differentiation

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Genes for Plant Autophagy: Functions and Interactions

Kim, S.-H., Kwon, C., Lee, J., & Chung, T. (2012) · Molecules and Cells · doi:10.1007/s10059-012-0098-y · Cited by 72

Polypyrimidine tract-binding protein 1-mediated down-regulation of ATG10 facilitates metastasis of colorectal cancer cells

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Sperm-borne miR-216b modulates cell proliferation during early embryo development via K-RAS

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Signaling and other functions of lipids in autophagy: a review

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Atg21 Is Required for Effective Recruitment of Atg8 to the Preautophagosomal Structure during the Cvt Pathway

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Mitophagy in hematopoietic stem cells

Joshi, A., & Kundu, M. (2013) · Autophagy · doi:10.4161/auto.26681 · Cited by 72

Cardiac Autophagy in Sepsis

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Autophagy in blood cancers: biological role and therapeutic implications

Nencioni, A., Cea, M., Montecucco, F., Longo, V. D., Patrone, F., Carella, A. M., Holyoake, T. L., & Helgason, G. V. (2013) · Haematologica · doi:10.3324/haematol.2012.079061 · Cited by 67

The Emerging Roles of Autophagy in Human Diseases

Lei, Y., & Klionsky, D. J. (2021) · Biomedicines · doi:10.3390/biomedicines9111651 · Cited by 68

Chemotherapy Resistance: Role of Mitochondrial and Autophagic Components

Bahar, E., Han, S., Kim, J., & Yoon, H. (2022) · Cancers · doi:10.3390/cancers14061462 · Cited by 67

Molecular Mechanisms of Autophagy in Cancer Development, Progression, and Therapy

Vitto, V. A. M., Bianchin, S., Zolondick, A. A., Pellielo, G., Rimessi, A., Chianese, D., Yang, H., Carbone, M., Pinton, P., Giorgi, C., et al. (2022) · Biomedicines · doi:10.3390/biomedicines10071596 · Cited by 73

Pineapple bromelain induces autophagy, facilitating apoptotic response in mammary carcinoma cells

Bhui, K., Tyagi, S., Prakash, B., & Shukla, Y. (2010) · BioFactors · doi:10.1002/biof.121 · Cited by 66

Mechanisms of CD4 T-cell depletion triggered by HIV-1 viral proteins.

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ABHD5 interacts with BECN1 to regulate autophagy and tumorigenesis of colon cancer independent of PNPLA2

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DHA-induced stress response in human colon cancer cells – Focus on oxidative stress and autophagy

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Impaired autophagy and delayed autophagic clearance of transforming growth factor β-induced protein (TGFBI) in granular corneal dystrophy type 2

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PINK1 signalling in cancer biology

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