Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor

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Autophagy and Cellular Senescence Mediated by Sox2 Suppress Malignancy of Cancer Cells

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Autophagy is involved in anticancer effects of matrine on SGC-7901 human gastric cancer cells

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Beclin 1 Biology and its Role in Heart Disease

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Autophagy function and its relationship to pathology, clinical applications, drug metabolism and toxicity

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Crosstalk between Fisetin-induced Apoptosis and Autophagy in Human Oral Squamous Cell Carcinoma

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Inhibition of autophagy enhances the effects of the AKT inhibitor MK‐2206 when combined with paclitaxel and carboplatin in BRAF wild‐type melanoma

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Autophagy regulation in the development and treatment of breast cancer

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Mir-30d increases intracellular survival ofHelicobacter pylorithrough inhibition of autophagy pathway

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Cell-cycle involvement in autophagy and apoptosis in yeast

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HIF-1a regulates hypoxia-induced autophagy via translocation of ANKRD37 in colon cancer

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Autophagy in hypoxia protects cancer cells against apoptosis induced by nutrient deprivation through a beclin1‐dependent way in hepatocellular carcinoma

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Drosophila as a model system to study autophagy

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Proteomics analysis of autophagy-deficient Atg7−/− MEFs reveals a close relationship between F-actin and autophagy

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Targeting Ca2+transport in cancer: close reality or long perspective?

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HACE1 Is a Tumor Suppressor Gene Candidate in Natural Killer Cell Neoplasms

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XIAP and cIAP1 amplifications induce Beclin 1-dependent autophagy through NFκB activation

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Upregulated SMYD3 promotes bladder cancer progression by targeting BCLAF1 and activating autophagy

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Electro-Magnetic Nano-Particle Bound Beclin1 siRNA Crosses the Blood–Brain Barrier to Attenuate the Inflammatory Effects of HIV-1 Infection in Vitro

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Transcription factor EB is involved in autophagy-mediated chemoresistance to doxorubicin in human cancer cells

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The ciliary protein RPGRIP1L governs autophagy independently of its proteasome-regulating function at the ciliary base in mouse embryonic fibroblasts

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Increased Amino Acid Uptake Supports Autophagy-Deficient Cell Survival upon Glutamine Deprivation

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Autophagy gene haploinsufficiency drives chromosome instability, increases migration, and promotes early ovarian tumors

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Dietary Energy Modulation and Autophagy: Exploiting Metabolic Vulnerabilities to Starve Cancer

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Aberrant Autolysosomal Regulation Is Linked to The Induction of Embryonic Senescence: Differential Roles of Beclin 1 and p53 in Vertebrate Spns1 Deficiency

Sasaki, T., Lian, S., Qi, J., Bayliss, P. E., Carr, C. E., Johnson, J. L., Guha, S., Kobler, P., Catz, S. D., Gill, M. S., et al. (2014) · PLoS Genetics · doi:10.1371/journal.pgen.1004409 · Cited by 57

Apoptosis regulation by autophagy gene 5

Yousefi, S., & Simon, H. (2007) · Critical Reviews in Oncology/Hematology · doi:10.1016/j.critrevonc.2007.06.005 · Cited by 55

Targeting cell death signaling in colorectal cancer: Current strategies and future perspectives

Koehler, B. C. (2014) · World Journal of Gastroenterology · doi:10.3748/wjg.v20.i8.1923 · Cited by 55

ATG proteins mediate efferocytosis and suppress inflammation in mammary involution

Teplova, I., Lozy, F., Price, S. M., Singh, S., Barnard, N., Cardiff, R. D., Birge, R. B., & Karantza, V. (2013) · Autophagy · doi:10.4161/auto.23164 · Cited by 56

Caenorhabditis elegansas a model for cancer research

Kyriakakis, E., Markaki, M., & Tavernarakis, N. (2014) · Molecular & Cellular Oncology · doi:10.4161/23723556.2014.975027 · Cited by 56

Autophagy in the placenta

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Glycine decarboxylase induces autophagy and is downregulated by miRNA-30d-5p in hepatocellular carcinoma

Zhuang, H., Wu, F., Wei, W., Dang, Y., Yang, B., Ma, X., Han, F., & Li, Y. (2019) · Cell Death and Disease · doi:10.1038/s41419-019-1446-z · Cited by 56

Beclin 1/Bcl-2 complex-dependent autophagy activity modulates renal susceptibility to ischemia-reperfusion injury and mediates renoprotection by Klotho

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Repurposing screen identifies Amlodipine as an inducer of PD-L1 degradation and antitumor immunity

Li, C., Yao, H., Wang, H., Fang, J., & Xu, J. (2020) · Oncogene · doi:10.1038/s41388-020-01592-6 · Cited by 54

Autophagy facilitates major histocompatibility complex class I expression induced by IFN-γ in B16 melanoma cells

Li, B., Zhang, L., Lichty, B. D., Li, D., Zhang, G., Feng, Z., Wan, Y., & Huang, B. (2009) · Cancer Immunology Immunotherapy · doi:10.1007/s00262-009-0752-1 · Cited by 54

Mammalian target of rapamycin (mTOR) pathway signalling in lymphomas

Drakos, E., Rassidakis, G. Z., & Medeiros, L. J. (2008) · Expert Reviews in Molecular Medicine · doi:10.1017/s1462399408000586 · Cited by 55

Nutrient Sensing in Cancer

Torrence, M. E., & Manning, B. D. (2017) · Annual Review of Cancer Biology · doi:10.1146/annurev-cancerbio-030617-050329 · Cited by 55

Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene

Qu, X., Yu, J., Bhagat, G., Furuya, N., Hibshoosh, H., Troxel, A., Rosen, J., Eskelinen, E.-L., Mizushima, N., Ohsumi, Y., et al. (2003) · Journal of Clinical Investigation · doi:10.1172/jci20039 · Cited by 2,311

Induction of autophagy and inhibition of tumorigenesis by beclin 1

Liang, X. H., Jackson, S., Seaman, M., Brown, K., Kempkes, B., Hibshoosh, H., & Levine, B. (1999) · Nature · doi:10.1038/45257 · Cited by 3,347

Autophagy, Beclin 1, and Their Relation To Oncogenesis

Sun, Y., & Peng, Z. (2008) · Laboratory Medicine · doi:10.1309/8l1x4x1wf3ugk77u · Cited by 13

New Insights Into Beclin-1: Evolution and Pan-Malignancy Inhibitor Activity

Wechman, S. L., Pradhan, A. K., DeSalle, R., Das, S. K., Emdad, L., Sarkar, D., & Fisher, P. B. (2017) · Advances in cancer research · doi:10.1016/bs.acr.2017.11.002 · Cited by 24

Research progress of autophagic gene Beclin 1 and tumor

We, Y. (2014) · Acta Medicinae Sinica