The DOI matches its Crossref record.
The extraordinary dielectric properties of biological materials and the action of enzymes.
Open accessAbstract
From very general theoretical considerations it is concluded that many biomolecules (i) should have metastable excited states with very high dipole moment, and (ii) should be capable of strongly excited giant dipole vibrations with frequencies near 10(11) Hz. Experimental evidence available so far seems to support these postulates. It is suggested that the two postulates should be of importance for the action of enzymes, and relevant experiments are proposed.
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Citations
Cited by
Hameroff, S., & Penrose, R. (2014) · Physics of Life Reviews · doi:10.1016/j.plrev.2013.08.002 · Cited by 983
“But even complex, active integration in Hodgkin–Huxley neurons would, apart from an entirely probabilistic (random) input, be completely algorithmic and deterministic, leaving no apparent place for a free will aspect of consciousness.”
BackgroundOrchestrated reduction of quantum coherence in brain microtubules: a model for consciousness
Hameroff, S., & Penrose, R. (1996) · Mathematics and Computers in Simulation · doi:10.1016/0378-4754(96)80476-9 · Cited by 641
Quantum computation in brain microtubules: decoherence and biological feasibility
Hagan, S., Hameroff, S. R., & Tuszyński, J. A. (2002) · Physical Review E · doi:10.1103/physreve.65.061901 · Cited by 389
On the role of organized multienzyme systems in cellular metabolism: a general synthesis
Welch, G. R. (1978) · Progress in Biophysics and Molecular Biology · doi:10.1016/0079-6107(78)90019-6 · Cited by 260
(1994) · Journal of Consciousness Studies · Cited by 216
The origins of quantum biology
McFadden, J., & Al-Khalili, J. (2018) · Proceedings of the Royal Society A: Mathematical, Physical and Engineering Sciences · doi:10.1098/rspa.2018.0674 · Cited by 192
Ionic wave propagation along actin filaments
Tuszyński, J. A., Portet, S., Dixon, J. M., Luxford, C., & Cantiello, H. F. (2004) · Biophysical Journal · doi:10.1016/s0006-3495(04)74255-1 · Cited by 163
Rasmussen, S., Karampurwala, H., Vaidyanath, R., Jensen, K. S., & Hameroff, S. (1990) · Physica D Nonlinear Phenomena · doi:10.1016/0167-2789(90)90093-5 · Cited by 153
Long range coherence in biological systems
Fröhlich, H. (1977) · La Rivista Del Nuovo Cimento Series 2 · doi:10.1007/bf02747279 · Cited by 137
Self-citation(1995) · Journal of Consciousness Studies · Cited by 111
How quantum brain biology can rescue conscious free will
Hameroff, S. (2012) · Frontiers in Integrative Neuroscience · doi:10.3389/fnint.2012.00093 · Cited by 95
'Orch OR' is the most complete, and most easily falsifiable theory of consciousness
Hameroff, S. (2021) · Cognitive Neuroscience · doi:10.1080/17588928.2020.1839037 · Cited by 84
“The Orch OR qubit Inside tubulin, pi-electron resonance forms ‘quantum friendly’ regions which extend to neighboring tubulins along helical lattice pathways to support collective ‘giant dipole oscillation’ qubits (Fröhlich, 1975; Figure 1).”
BackgroundCoherent Quantum Electrodynamics in Living Matter
Del Giudice, E., De Ninno, A., Fleischmann, M., Mengoli, G., Milani, M., Talpo, G., & Vitiello, G. (2005) · Electromagnetic Biology and Medicine · doi:10.1080/15368370500379574 · Cited by 79
Anesthesia, consciousness and hydrophobic pockets–a unitary quantum hypothesis of anesthetic action
Hameroff, S. (1998) · Toxicology Letters · doi:10.1016/s0378-4274(98)00162-3 · Cited by 62
Craddock, T. J. A., Priel, A., & Tuszynski, J. A. (2014) · Journal of Integrative Neuroscience · doi:10.1142/s0219635214400019 · Cited by 38
Millimeter wave absorption spectra of biological samples
Gandhi, O. P., Hagmann, M. J., Hill, D. W., Partlow, L. M., & Bush, L. (1980) · Bioelectromagnetics · doi:10.1002/bem.2250010305 · Cited by 30
Georgiev, D. (2007) · NeuroQuantology · doi:10.14704/nq.2007.5.1.121 · Cited by 16
“A pioneering work in that direction was done already by Fröhlich (1968, 1975, 1984, 1986).”
BackgroundBushell, W. C. (2009) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2009.04960.x · Cited by 12
Metadata
- Authors
- Fröhlich, H.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 1975-11
- Volume
- 72
- Issue
- 11
- Pages
- 4211-4215
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W2092797887
- Cited by
- 316
- References
- 0
- FWCI
- 2.39
- Type
- journal article
- Language
- en
- Open access
- green
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