The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Mammalian nitrate biosynthesis: incorporation of 15NH3 into nitrate is enhanced by endotoxin treatment.
Open accessAbstract
Incorporation of an oral dose of [15N]ammonium acetate into urinary [15N]nitrate has been demonstrated in the rat. Investigation of the regulation of nitrate synthesis has shown that Escherichia coli lipopolysaccharide potently stimulates urinary nitrate excretion (9-fold increase). It was further shown that the enhanced rate of nitrate excretion by lipopolysaccharide was due not to a reduction in nitrate metabolic loss but rather to an increased rate of synthesis. This conclusion was based on finding a proportionally increased incorporation of [15N]ammonium into nitrate nitrogen with lipopolysaccharide treatment. Nitrate biosynthesis was also increased by intraperitoneal injection of carrageenan and subcutaneous injection of turpentine. It is proposed that the pathway of nitrate biosynthesis may be the result of oxidation of reduced nitrogen compounds by oxygen radicals generated by an activated reticuloendothelial system.
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Cites
Nitrite and nitrate are formed by endogenous synthesis in the human intestine
Tannenbaum, S. R., Fett, D., Young, V. R., Land, P. D., & Bruce, W. R. (1978) · Science · doi:10.1126/science.663630 · Cited by 284
Self-citationNitrite in Human Saliva. Its Possible Relationship to Nitrosamine Formation23
Tannenbaum, S. R., Sinskey, A. J., Weisman, M., & Bishop, W. (1974) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/53.1.79 · Cited by 237
Self-citationEpidemiological and toxicological aspects of nitrates and nitrites in the environment
Shuval, H. I., & Gruener, N. (1972) · American Journal of Public Health · doi:10.2105/ajph.62.8.1045 · Cited by 158
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Nitric oxide as a secretory product of mammalian cells
Nathan, C. (1992) · The FASEB Journal · doi:10.1096/fasebj.6.12.1381691 · Cited by 4,350
Arginine metabolism: nitric oxide and beyond
WU, G., & MORRIS, S. M. (1998) · Biochemical Journal · doi:10.1042/bj3360001 · Cited by 2,811
Stuehr, D. J., & Marletta, M. A. (1985) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.82.22.7738 · Cited by 1,126
Guanylate cyclase and the ⋅NO/cGMP signaling pathway
Denninger, J. W., & Marletta, M. A. (1999) · Biochimica et Biophysica Acta (BBA) - Bioenergetics · doi:10.1016/s0005-2728(99)00024-9 · Cited by 1,040
Mammalian nitric oxide synthases
Stuehr, D. J. (1999) · Biochimica et Biophysica Acta (BBA) - Bioenergetics · doi:10.1016/s0005-2728(99)00016-x · Cited by 996
Metadata
- Authors
- Wagner, D. A., Young, V. R., & Tannenbaum, S. R.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 1983-07
- Volume
- 80
- Issue
- 14
- Pages
- 4518-4521
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W2010568219
- Cited by
- 205
- References
- 3
- FWCI
- 1.89
- Type
- journal article
- Language
- en
- Open access
- green
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- Wagner, D. A., Young, V. R., & Tannenbaum, S. R. (1983). Mammalian nitrate biosynthesis: incorporation of 15NH3 into nitrate is enhanced by endotoxin treatment. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.80.14.4518
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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