The DOI matches its Crossref record; 11 of the 11 references it cites were found in a registry or an index.
Identification of a gene, MLL, that spans the breakpoint in 11q23 translocations associated with human leukemias.
Open accessAbstract
Recurring chromosomal translocations involving chromosome 11, band q23, have been observed in acute lymphoid leukemias and especially in acute myeloid leukemias. We recently showed that breakpoints in four 11q23 translocations, t(4;11)(q21;q23), t(6;11)(q27;q23), t(9;11)(p22;q23), and t(11;19)(q23;p13.3), were contained within a yeast artificial chromosome clone bearing the CD3D and CD3G gene loci. We have identified within the CD3 yeast artificial chromosome a transcription unit that spans the breakpoint junctions of the 4;11, 9;11, and 11;19 translocations, and we describe two other, related transcripts that are upregulated in the RS4;11 cell line. We have named this gene MLL (myeloid/lymphoid, or mixed-lineage, leukemia.
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Monoubiquitination of Human Histone H2B: The Factors Involved and Their Roles in HOX Gene Regulation
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Metadata
- Authors
- Ziemin-van der Poel, S., McCabe, N. R., Gill, H. J., Espinosa, R., Patel, Y., Harden, A., Rubinelli, P., Smith, S. D., LeBeau, M. M., & Rowley, J. D.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 1991-12
- Volume
- 88
- Issue
- 23
- Pages
- 10735-10739
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W2112087352
- Cited by
- 585
- References
- 11
- FWCI
- 19.37
- Type
- journal article
- Language
- en
- Open access
- green
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- The paper
- Ziemin-van der Poel, S., McCabe, N. R., Gill, H. J., Espinosa, R., Patel, Y., Harden, A., Rubinelli, P., Smith, S. D., LeBeau, M. M., & Rowley, J. D. (1991). Identification of a gene, MLL, that spans the breakpoint in 11q23 translocations associated with human leukemias. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.88.23.10735
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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