The DOI matches its Crossref record; 14 of the 14 references it cites were found in a registry or an index.
Regional and cellular fractionation of working memory
Open accessAbstract
This chapter recounts efforts to dissect the cellular and circuit basis of a memory system in the primate cortex with the goal of extending the insights gained from the study of normal brain organization in animal models to an understanding of human cognition and related memory disorders. Primates and humans have developed an extraordinary capacity to process information “on line,” a capacity that is widely considered to underlay comprehension, thinking, and so-called executive functions. Understanding the interactions between the major cellular constituents of cortical circuits—pyramidal and nonpyramidal cells—is considered a necessary step in unraveling the cellular mechanisms subserving working memory mechanisms and, ultimately, cognitive processes. Evidence from a variety of sources is accumulating to indicate that dopamine has a major role in regulating the excitability of the cortical circuitry upon which the working memory function of prefrontal cortex depends. Here, I describe several direct and indirect intercellular mechanisms for modulating working memory function in prefrontal cortex based on the localization of dopamine receptors on the distal dendrites and spines of pyramidal cells and on interneurons in the prefrontal cortex. Interactions between monoamines and a compromised cortical circuitry may hold the key to understanding the variety of memory disorders associated with aging and disease.
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Cites
Human Memory: A Proposed System and its Control Processes
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Mnemonic coding of visual space in the monkey's dorsolateral prefrontal cortex
Funahashi, S., Bruce, C. J., & Goldman-Rakic, P. S. (1989) · Journal of Neurophysiology · doi:10.1152/jn.1989.61.2.331 · Cited by 2,685
Self-citationThe neural correlates of the verbal component of working memory
Paulesu, E., Frith, C. D., & Frackowiak, R. S. J. (1993) · Nature · doi:10.1038/362342a0 · Cited by 2,230
Modulation of memory fields by dopamine Dl receptors in prefrontal cortex
Williams, G. V., & Goldman-Rakic, P. S. (1995) · Nature · doi:10.1038/376572a0 · Cited by 1,593
Self-citationPractice-related Changes in Human Brain Functional Anatomy during Nonmotor Learning
Raichle, M. E., Fiez, J. A., Videen, T. O., MacLeod, A.-M. K., Pardo, J. V., Fox, P. T., & Petersen, S. E. (1994) · Cerebral Cortex · doi:10.1093/cercor/4.1.8 · Cited by 1,593
Cognitive Deficit Caused by Regional Depletion of Dopamine in Prefrontal Cortex of Rhesus Monkey
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Activation of the prefrontal cortex in a nonspatial working memory task with functional MRI
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Demonstrating the implicit processing of visually presented words and pseudowords
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Localization of dopamine D4 receptors in GABAergic neurons of the primate brain
Mrzljak, L., Bergson, C., Pappy, M., Huff, R., Levenson, R., & Goldman-Rakic, P. S. (1996) · Nature · doi:10.1038/381245a0 · Cited by 494
Self-citationMcCarthy, G., Blamire, A. M., Puce, A., Nobre, A. C., Bloch, G., Hyder, F., Goldman-Rakic, P., & Shulman, R. G. (1994) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.91.18.8690 · Cited by 459
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Cited by
LeDoux, J. E. (2000) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.23.1.155 · Cited by 8,444
Mesulam, M. (1998) · Brain · doi:10.1093/brain/121.6.1013 · Cited by 3,072
The Emotional Brain, Fear, and the Amygdala
LeDoux, J. (2003) · Cellular and Molecular Neurobiology · doi:10.1023/a:1025048802629 · Cited by 1,818
Stress, Depression, and Neuroplasticity: A Convergence of Mechanisms
Pittenger, C., & Duman, R. S. (2008) · Neuropsychopharmacology · doi:10.1038/sj.npp.1301574 · Cited by 1,795
Niendam, T. A., Laird, A. R., Ray, K. L., Dean, Y. M., Glahn, D. C., & Carter, C. S. (2012) · Cognitive, Affective, & Behavioral Neuroscience · doi:10.3758/s13415-011-0083-5 · Cited by 1,700
“From a traditional cognitive or neuropsychological perspective, executive functions have been thought to comprise a set of distinct cognitive domains that include vigilance, or sustained attention (Pennington & Ozonoff, 1996; Smith & Jonides, 1999); initiation of complex goal-directed behaviors (Lezak, 1995); inhibiti…”
Background
Metadata
- Authors
- Goldman-Rakic, P. S.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 1996-11-26
- Volume
- 93
- Issue
- 24
- Pages
- 13473-13480
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W2089649622
- Cited by
- 812
- References
- 14
- FWCI
- 7.53
- Type
- journal article
- Language
- en
- Open access
- green
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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