A post-tetanic time window for the reinforcement of long-term potentiation by appetitive and aversive stimuli

A synaptic model of memory: long-term potentiation in the hippocampus

Bliss, T. V. P., & Collingridge, G. L. (1993) · Nature · doi:10.1038/361031a0 · Cited by 11,566

Long‐lasting potentiation of synaptic transmission in the dentate area of the unanaesthetized rabbit following stimulation of the perforant path

Bliss, T. V. P., & Gardner-Medwin, A. R. (1973) · The Journal of Physiology · doi:10.1113/jphysiol.1973.sp010274 · Cited by 7,424

Selective impairment of learning and blockade of long-term potentiation by an N-methyl-D-aspartate receptor antagonist, AP5

Morris, R. G. M., Anderson, E., Lynch, G. S., & Baudry, M. (1986) · Nature · doi:10.1038/319774a0 · Cited by 3,640

Time-Dependent Processes in Memory Storage: Recent studies of learning and memory indicate that memory storage involves time-dependent processes.

McGaugh, J. L. (1966) · Science · doi:10.1126/science.153.3742.1351 · Cited by 1,468

β-Adrenergic activation and memory for emotional events

Cahill, L., Prins, B., Weber, M., & McGaugh, J. L. (1994) · Nature · doi:10.1038/371702a0 · Cited by 1,271

The Structure and Organization of Memory

Squire, L. R., Knowlton, B. J., & Musen, G. (1993) · Annual Review of Psychology · doi:10.1146/annurev.ps.44.020193.002321 · Cited by 1,159

Neurobiology of learning and memory

Delacour, J. (1985) · Neuropsychologia · doi:10.1016/0028-3932(85)90073-9 · Cited by 1,026

A motivational view of learning, performance, and behavior modification.

Bindra, D. (1974) · Psychological Review · doi:10.1037/h0036330 · Cited by 594

Involvement Of Hormonal And Neuromodulatory Systems In The Regulation Of Memory Storage

McGaugh, J. L. (1989) · Annual Review of Neuroscience · doi:10.1146/annurev.ne.12.030189.001351 · Cited by 566

Inescapable versus escapable shock modulates long-term potentiation in the rat hippocampus

Shors, T. J., Seib, T. B., Levine, S., & Thompson, R. F. (1989) · Science · doi:10.1126/science.2704997 · Cited by 458

Subcortical deafferentation impairs behavioral reinforcement of long-term potentiation in the dentate gyrus of freely moving rats

Almaguer‐Melian, W., Rosillo, J. C., Frey, J. U., & Bergado, J. A. (2006) · Neuroscience · doi:10.1016/j.neuroscience.2005.12.003 · Cited by 19

Modulation of extracellular monoamine transmitter concentrations in the hippocampus after weak and strong tetanization of the perforant path in freely moving rats

Neugebauer, F., Korz, V., & Frey, J. U. (2009) · Brain Research · doi:10.1016/j.brainres.2009.03.055 · Cited by 18

Psychopharmacological possibilities in the acute disaster setting

Simon, A. B., & Gorman, J. M. (2004) · Psychiatric Clinics of North America · doi:10.1016/j.psc.2004.03.004 · Cited by 18

Neurobiological Basis of the Complex Effects of Stress on Memory and Synaptic Plasticity

Zoladz, P. R., Park, C. R., & Diamond, D. M. (2011) · Wiley eBooks · doi:10.1002/9781118083222.ch8 · Cited by 16

Priming stimulation of basal but not lateral amygdala affects long-term potentiation in the rat dentate gyrus in vivo

Li, Z., & Richter‐Levin, G. (2013) · Neuroscience · doi:10.1016/j.neuroscience.2013.03.059 · Cited by 15

Predictive Place-Cell Sequences for Goal-Finding Emerge from Goal Memory and the Cognitive Map: A Computational Model

Gönner, L., Vitay, J., & Hamker, F. H. (2017) · Frontiers in Computational Neuroscience · doi:10.3389/fncom.2017.00084 · Cited by 16

Distribution and classification of the extracellular matrix in the olfactory bulb

Hunyadi, A., Gaál, B., Matesz, C., Mészár, Z., Morawski, M., Reimann, K., Lendvai, D., Alpár, A., Wéber, I., & Rácz, É. (2019) · Brain Structure and Function · doi:10.1007/s00429-019-02010-8 · Cited by 14

Hippocampal neurotrophins after stimulation of the basolateral amygdala, and memory improvement in lesioned rats

Mercerón‐Martínez, D., Almaguer‐Melian, W., Serrano, T., Lorigados, L., Fuentes, N. P., & Bergado, J. A. (2013) · Restorative Neurology and Neuroscience · doi:10.3233/rnn-120265 · Cited by 12

Differential effects of electrical stimulation patterns, motivational-behavioral stimuli and their order of application on functional plasticity processes within one input in the dentate gyrus of freely moving rats in vivo

Almaguer‐Melian, W., Bergado, J. A., Lopez‐Rojas, J., Frey, S., & Frey, J. U. (2009) · Neuroscience · doi:10.1016/j.neuroscience.2009.11.068 · Cited by 12

Disruption of Perceptual Learning by a Brief Practice Break

Little, D., Zhang, Y.-X., & Wright, B. A. (2017) · Current Biology · doi:10.1016/j.cub.2017.10.032 · Cited by 11

Amygdala stimulation promotes recovery of behavioral performance in a spatial memory task and increases GAP-43 and MAP-2 in the hippocampus and prefrontal cortex of male rats

Mercerón‐Martínez, D., Almaguer‐Melian, W., Alberti‐Amador, E., & Bergado, J. A. (2018) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2018.06.008 · Cited by 10

Emotional and cognitive information processing: Relations to behavioral performance and hippocampal long-term potentiation in vivo during a spatial water maze training in ratsPreprint

Schulz, K., & Korz, V. (2010) · Learning & Memory · doi:10.1101/lm.1855610 · Cited by 11

Dentate gyrus norepinephrine ramping facilitates aversive contextual processing

Zhang, E. T., Saglimbeni, G. S., Feng, J., Li, Y., & Bruchas, M. R. (2025) · Nature Communications · doi:10.1038/s41467-025-55817-x · Cited by 10

Facilitation of fear extinction by novelty is modulated by β-adrenergic and 5-HT1A serotoninergic receptors in hippocampus

Nachtigall, E. G., Furini, C. R. G., Behling, J. A. K., Farias, C. P., Izquierdo, I., & Myskiw, J. D. C. (2019) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2019.107101 · Cited by 11

Behavioral reinforcement of long-term potentiation is impaired in aged rats with cognitive deficiencies

Bergado, J. A., Almaguer, W., Ravelo, J. N., Rosillo, J. C., & Frey, J. U. (2001) · Neuroscience · doi:10.1016/s0306-4522(01)00520-6 · Cited by 10

Basolateral amygdala stimulation does not recruit LTP at depotentiated synapses

Almaguer‐Melian, W., Bergado, J. A., Martí, L. M., Duany, C., & Frey, J. U. (2010) · Physiology & Behavior · doi:10.1016/j.physbeh.2010.07.007 · Cited by 8

Immediate post-defeat infusions of the noradrenergic receptor antagonist propranolol impair the consolidation of conditioned defeat in male Syrian hamsters

Gray, C. L., Krebs‐Kraft, D. L., Solomon, M. B., Norvelle, A., Parent, M. B., & Huhman, K. L. (2015) · Physiology & Behavior · doi:10.1016/j.physbeh.2015.09.010 · Cited by 9

Modulation of long-term and short-term plasticity in the dentate gyrus granule cells by activating the β-adrenergic receptors of the basolateral amygdala

Noorani, S. K., Hojati, V., Ardeshiri, M. R., Akbari, E., & Ehsani, S. (2020) · Neuroscience Letters · doi:10.1016/j.neulet.2020.134878 · Cited by 10

Basolateral amygdala stimulation plus water maze training restore dentate gyrus LTP and improve spatial learning and memory

Mercerón‐Martínez, D., Almaguer‐Melian, W., & Bergado, J. A. (2021) · Behavioural Brain Research · doi:10.1016/j.bbr.2021.113589 · Cited by 6

Emotional Tagging and Long-Term Memory Formation

Richter‐Levin, G., Kehat, O., & Anunu, R. (2014) · Springer eBooks · doi:10.1007/978-1-4939-1761-7_13 · Cited by 7

Neuromodulators of LTP and NCAMs in the amygdala and hippocampus in response to stress

Guterman, A., & Richter‐Levin, G. (2006) · Birkhäuser Basel eBooks · doi:10.1007/978-3-7643-7772-4_7 · Cited by 7

Blockade of dorsal hippocampal orexin-1 receptors impaired morphine-induced state-dependent learning

Farahmandfar, M., Kadivar, M., & Rastipisheh, S. (2016) · Neuropeptides · doi:10.1016/j.npep.2016.10.002 · Cited by 7

Involvement of the amygdala in the neuroendocrine and behavioral consequences of stress

Akirav, I., & Richter‐Levin, G. (2005) · Techniques in the behavioral and neural sciences · doi:10.1016/s0921-0709(05)80042-2 · Cited by 6

Amygdala stimulation ameliorates memory impairments and promotes c‐Fos activity in fimbria‐fornix‐lesioned rats

Mercerón‐Martínez, D., Almaguer‐Melian, W., Alberti‐Amador, E., Calderón‐Peña, R., & Bergado, J. A. (2020) · Synapse · doi:10.1002/syn.22179 · Cited by 6

Amylovis-201 enhances physiological memory formation and rescues memory and hippocampal cell loss in a streptozotocin-induced Alzheimer's disease animal model

Mercerón‐Martínez, D., Ricardo, L. A., Pina, A. B., Rojo, N. O., Seco, A. E., Hurtado, Y. V., Días, B. E., Fernández, I., García-Pupo, L., Sablón-Carrazana, M., et al. (2024) · Brain Research · doi:10.1016/j.brainres.2024.148848 · Cited by 5

The Impact of Emotional Arousal on Amygdala Activity, Memory Consolidation, and Long-Term Potentiation in the Hippocampus

Zhang, I. (2022) · Journal of Student Research · doi:10.47611/jsr.v11i2.1614 · Cited by 6

Stimulation of the nucleus raphe medialis modifies basal synaptic transmission at the dentate gyrus, but not long-term potentiation or its reinforcement by stimulation of the basolateral amygdala

Bergado, J. A., Scherf, T., Almaguer‐Melian, W., Frey, S., Lopez‐Rojas, J., & Frey, J. U. (2009) · Neuroscience Letters · doi:10.1016/j.neulet.2009.08.034 · Cited by 5

Morphine-induced potentiation in the dentate gyrus of the hippocampus involves norepinephrine

Zhu, H., & Zhou, W. (2003) · European Journal of Pharmacology · doi:10.1016/s0014-2999(03)01601-7 · Cited by 4

Noradrenergic action in prefrontal cortex in the late stage of memory consolidation

Tronel, S., Moricard, Y., & Sara, S. J. (2003) · Acta Neurobiologiae Experimentalis · Cited by 4

The Three Faces of Norepinephrine: Plasticity at the Perforant Path-Dentate Gyrus Synapse

Harley, C. W., Walling, S. G., & Brown, R. A. M. (2005) · Springer eBooks · doi:10.1007/0-387-25443-9_1 · Cited by 4

Hormetic and Non-Hormetic Dose-Response Functions in Stress Effects on Memory and Synaptic Plasticity: Issues and Mechanisms

Zoladz, P. R., & Diamond, D. M. (2008) · American Journal of Pharmacology and Toxicology · doi:10.3844/ajptsp.2008.111.124 · Cited by 4

Computational modelling of memory retention from synapse to behaviour

van Rossum, M. C. W., & Shippi, M. (2013) · Journal of Statistical Mechanics Theory and Experiment · doi:10.1088/1742-5468/2013/03/p03007 · Cited by 5

The Role of Synaptic Tagging and Capture for Memory Dynamics in Spiking Neural Networks

Luboeinski, J. (2021) · eDiss (Georg-August-Universität Göttingen) · doi:10.53846/goediss-463 · Cited by 4

Behavioral tagging: Synaptic event or cellular alteration?

Korz, V. (2017) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2017.12.005 · Cited by 3

Amygdala stimulation transforms short-term memory into remote memory by persistent activation of atypical PKC in the anterior cingulate cortex

Almaguer‐Melian, W., Mercerón‐Martínez, D., Alacán‐Ricardo, L., Pina, A. B., Hsieh, C., Bergado, J. A., & Sacktor, T. C. (2024) · Neuroscience · doi:10.1016/j.neuroscience.2025.01.065 · Cited by 2

A unique erythropoietin dosage induces the recovery of long-term synaptic potentiation in fimbria-fornix lesioned rats

Almaguer‐Melian, W., Mercerón‐Martínez, D., & Bergado, J. A. (2022) · Brain Research · doi:10.1016/j.brainres.2022.148178 · Cited by 2

Evolutionary, Historical and Mechanistic Perspectives on How Stress Affects Memory and Hippocampal Synaptic Plasticity

Farmer, G. E., Park, C. R., Bullard, L. A., & Diamond, D. M. (2014) · Springer eBooks · doi:10.1007/978-1-4939-1056-4_10 · Cited by 2

Analysis of conditions that are important for the beginning of consolidation in a model of long-term synaptic potentiation

Kudryashova, I. V. (2013) · Neurochemical Journal · doi:10.1134/s1819712413030070 · Cited by 2

Relationship between Long-Term Potentiation and the Initial Properties of CA3–CA1 Synapses: Importance of the Effects of External Factors on Hippocampal Synaptic Plasticity for Studies

Kudryashova, I. V. (2019) · Neuroscience and Behavioral Physiology · doi:10.1007/s11055-019-00776-2 · Cited by 2

A computational inquiry into navigation, with particular reference to the hippocampus

Foster, D. J. (1999) · ERA · Cited by 1

Behaviorally Induced Synaptic Tagging

Myskiw, J. D. C., Furini, C. R. G., & Izquierdo, I. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-809324-5.21122-x · Cited by 1

Langzeitpotenzierung im Hippokampus: Entdeckung, Mechanismen und Funktion

Bliss, T., Collingridge, G. L., Morris, R., & Reymann, K. G. (2018) · e-Neuroforum · doi:10.1515/nf-2017-0059 · Cited by 1

Mecanismos fisiológicos en la modulación afectiva de procesos de plasticidad sináptica

Rosado, B., & Alberto, J. A. N. (2011)

On the role of the hippocampus in the acquisition, long-term retention and semanticisation of memory

Gingell, S. (2005) · ERA

FACTORS THAT DETERMINE THE NON-LINEAR AMYGDALA INFLUENCE ON

Akirav, I., & Richter‐Levin, G. (2014)

Metaplasticity Tunes Functional Plasticity in the Rodent Hippocampus

Li, Q. (2015) · Digitale Bibliothek Braunschweig (Verbundzentrale Göttingen (VZG)) · doi:10.24355/dbbs.084-201503260942-0

Faculty Opinions recommendation of Requirement of beta-adrenergic receptor activation and protein synthesis for LTP-reinforcement by novelty in rat dentate gyrus.

Lisman, J. E. (2004) · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · doi:10.3410/f.1018259.206720

Faculty Opinions recommendation of Mechanisms of amygdala modulation of hippocampal plasticity.

McGaugh, J. L. (2002) · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · doi:10.3410/f.1010873.169108

A Unique Erythropoietin Dosage Induces the Recovery of Long-Term Synaptic Potentiation in Fimbria-Fornix Lesioned RatsPreprint

Bergado, J. A., Almaguer‐Melian, W., & Mercerón‐Martínez, D. (2022) · SSRN Electronic Journal · doi:10.2139/ssrn.4159245

Emotional Tagging and Long-Term Memory Formation

Richter‐Levin, G., Kehat, O., & Anunu, R. (2024) · Springer eBooks · doi:10.1007/978-3-031-54864-2_18

Amygdala stimulation transforms short-term memory into remote memory by persistent activation of atypical PKC in the anterior cingulate cortexPreprint

Almaguer‐Melian, W., Mercerón‐Martínez, D., Alacán‐Ricardo, L., Pina, A. B., Hsieh, C., Bergado, J. A., & Sacktor, T. C. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.09.17.613040

Adaptive synaptic mechanisms: The role of metaplasticity in synaptic tagging and capture

Jayapragas, S., Yin, L. S., & Sajikumar, S. (2024) · Elsevier eBooks · doi:10.1016/b978-0-443-15754-7.00065-1

From Erythropoiesis to Circuit Rewiring: Erythropoietin as a Precision Tool for Neurorestoration

Almaguer‐Melian, W., Mercerón‐Martínez, D., Acosta, B. B., & Bergado, J. A. (2026) · International Journal of Molecular Sciences · doi:10.3390/ijms27104329

[These authors contributed equally (shared senior authorship): Markus Werkle-Bergner, Mara Mather.]

Dahl, M., Kulesza, A., Werkle‐Bergner, M., & Mather, M. (2023) · MPG.PuRe (Max Planck Society)

Involvement of β-adrenergic receptors in protein synthesis-dependent late long-term potentiation (LTP) in the dentate gyrus of freely moving rats: the critical role of the LTP induction strength

Straube, T., & Frey, J. U. (2003) · Neuroscience · doi:10.1016/s0306-4522(03)00151-9 · Cited by 72

Requirement of β‐adrenergic receptor activation and protein synthesis for LTP‐reinforcement by novelty in rat dentate gyrus

Straube, T., Korz, V., Balschun, D., & Frey, J. U. (2003) · The Journal of Physiology · doi:10.1113/jphysiol.2003.049452 · Cited by 157

Differential effects of electrical stimulation patterns, motivational-behavioral stimuli and their order of application on functional plasticity processes within one input in the dentate gyrus of freely moving rats in vivo

Almaguer‐Melian, W., Bergado, J. A., Lopez‐Rojas, J., Frey, S., & Frey, J. U. (2009) · Neuroscience · doi:10.1016/j.neuroscience.2009.11.068 · Cited by 12

β-Adrenergic Mechanisms in Long-Term Potentiation and Norepinephrine-Induced Long-Lasting Potentiation

Sarvey, J. M. (1988) · Springer eBooks · doi:10.1007/978-1-4757-9610-0_8 · Cited by 7

Hormonal and monoamine signaling during reinforcement of hippocampal long-term potentiation and memory retrievalPreprint

Korz, V., & Frey, J. U. (2007) · Learning & Memory · doi:10.1101/lm.459807 · Cited by 37