The DOI matches its Crossref record; 47 of the 47 references it cites were found in a registry or an index.
A bacterial cytokine
Open accessAbstract
Viable cells of Micrococcus luteus secrete a factor, which promotes the resuscitation and growth of dormant, nongrowing cells of the same organism. The resuscitation-promoting factor (Rpf) is a protein, which has been purified to homogeneity. In picomolar concentrations, it increases the viable cell count of dormant M. luteus cultures at least 100-fold and can also stimulate the growth of viable cells. Rpf also stimulates the growth of several other high G+C Gram-positive organisms, including Mycobacterium avium, Mycobacterium bovis (BCG), Mycobacterium kansasii , Mycobacterium smegmatis, and Mycobacterium tuberculosis . Similar genes are widely distributed among high G+C Gram-positive bacteria; genome sequencing has uncovered examples in Mycobacterium leprae and Mb. tuberculosis and others have been detected by hybridization in Mb. smegmatis , Corynebacterium glutamicum, and Streptomyces spp. The mycobacterial gene products may provide different targets for the detection and control of these important pathogens. This report is thus a description of a proteinaceous autocrine or paracrine bacterial growth factor or cytokine.
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Cites
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Cited by
Bacterial Growth and Cell Division: a Mycobacterial Perspective
Hett, E. C., & Rubin, E. J. (2008) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.00028-07 · Cited by 408
Dahl, J. L., Kraus, C. N., Boshoff, H. I. M., Doan, B., Foley, K., Avarbock, D., Kaplan, G., Mizrahi, V., Rubin, H., & Barry, C. E. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1631248100 · Cited by 349
Kana, B. D., Gordhan, B. G., Downing, K. J., Sung, N., Vostroktunova, G., Machowski, E. E., Tsenova, L., Young, M., Kaprelyants, A., Kaplan, G., et al. (2008) · Molecular Microbiology · doi:10.1111/j.1365-2958.2007.06078.x · Cited by 295
Self-citationThe rpf gene of Micrococcus luteus encodes an essential secreted growth factor
Mukamolova, G. V., Turapov, O. A., Kazarian, K., Telkov, M., Kaprelyants, A. S., Kell, D. B., & Young, M. (2002) · Molecular Microbiology · doi:10.1046/j.1365-2958.2002.03183.x · Cited by 178
Self-citationShiloh, M. U., & DiGiuseppe Champion, P. A. (2010) · Current Opinion in Microbiology · doi:10.1016/j.mib.2009.11.006 · Cited by 137
Metadata
- Authors
- Mukamolova, G. V., Kaprelyants, A. S., Young, D. I., Young, M., & Kell, D. B.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 1998-07-21
- Volume
- 95
- Issue
- 15
- Pages
- 8916-8921
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W2058208662
- Cited by
- 448
- References
- 47
- FWCI
- 6.64
- Type
- journal article
- Language
- en
- Open access
- green
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- Mukamolova, G. V., Kaprelyants, A. S., Young, D. I., Young, M., & Kell, D. B. (1998). A bacterial cytokine. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.95.15.8916
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