The DOI matches its Crossref record; 43 of the 43 references it cites were found in a registry or an index.
Regulatory evolution and the origin of the bilaterians
Open accessAbstract
The adult body plan of bilaterians is achieved by imposing regional specifications on pluripotential cells. The establishment of spatial domains is governed in part by regulating expression of transcription factors. The key to understanding bilaterian evolution is contingent on our understanding of how the regulation of these transcription factors influenced bilaterian stem-group evolution.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“Molecular and morphological phylogenies agree that the bilaterian stem group emerged from a common ancestor of bilaterians and cnidarians, which probably existed much deeper in time (Peterson and Eernisse, 2001;Medina et al., 2001;Peterson and Davidson, 2000).”
From Precambrian Animal Life: Probable Developmental and Adult Cnidarian Forms from Southwest China (2002) · cites this paper as Peterson and Davidson, 2000
In the citing paper
“Molecular and morphological phylogenies agree that the bilaterian stem group emerged from a common ancestor of bilaterians and cnidarians, which probably existed much deeper in time (Peterson and Eernisse, 2001;Medina et al., 2001;Peterson and Davidson, 2000).”
From Precambrian Animal Life: Probable Developmental and Adult Cnidarian Forms from Southwest China (2002) · cites this paper as Peterson and Davidson, 2000
Citations
Cites
Patterning the Vertebrate Neuraxis
Lumsden, A., & Krumlauf, R. K. (1996) · Science · doi:10.1126/science.274.5290.1109 · Cited by 1,142
Fossils, genes and the evolution of animal limbs
Shubin, N. H., Tabin, C. J., & Carroll, S. B. (1997) · Nature · doi:10.1038/41710 · Cited by 801
Repetitive and Non-Repetitive DNA Sequences and a Speculation on the Origins of Evolutionary Novelty
Britten, R. J., & Davidson, E. H. (1971) · The Quarterly Review of Biology · doi:10.1086/406830 · Cited by 789
Self-citationThe zootype and the phylotypic stage
Slack, J. M. W., Holland, P. W. H., & Graham, C. F. (1993) · Nature · doi:10.1038/361490a0 · Cited by 699
Intertidal Invertebrates of California.
Ghiselin, M. T., Morris, R. H., Abbott, D. P., & Haderlie, E. C. (1981) · Systematic Zoology · doi:10.2307/2992426 · Cited by 559
Hox genes in brachiopods and priapulids and protostome evolution
de Rosa, R., Grenier, J. K., Andreeva, T., Cook, C. E., Adoutte, A., Akam, M., Carroll, S. B., & Balavoine, G. (1999) · Nature · doi:10.1038/21631 · Cited by 541
Intertidal Invertebrates of California
Morris, R. H., Abbott, D. P., & Haderlie, E. C. (1980) · Cited by 508
Analysis of Hox gene expression in the chick limb bud
Nelson, C. E., Morgan, B. A., Burke, A. C., Laufer, E., DiMambro, E., Murtaugh, L. C., Gonzales, E., Tessarollo, L., Parada, L. F., & Tabin, C. J. (1996) · Development · doi:10.1242/dev.122.5.1449 · Cited by 483
Taylor, H. S., Vanden Heuvel, G. B., & Igarashi, P. (1997) · Biology of Reproduction · doi:10.1095/biolreprod57.6.1338 · Cited by 463
Ligand binding was acquired during evolution of nuclear receptors
Escrivá, H., Safi, R., Hänni, C., Langlois, M., Saumitou‐Laprade, P., Stéhelin, D., Capron, A., Pierce, R. J., & Laudet, V. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.13.6803 · Cited by 403
Flagged first, then by citations
Research works printed but not linked: 1
- J R Finnerty, V A Master, S Irvine, M J Kourakis, S Warriner, M Q Martindale Mol Mar Biol Biotechnol 5, 249–258 (1996).
Cited by
Sorted by citations
Items 101–139 of 139
Molecular Paleobiology and the Cambrian Explosion: 21stCentury Answers to 19thCentury Problems
Peterson, K. J. (2008) · The Paleontological Society Papers · doi:10.1017/s1089332600001637 · Cited by 2
Self-citationSchmidt‐Rhaesa, A. (2007) · Oxford University Press eBooks · doi:10.1093/acprof:oso/9780198566687.003.0007 · Cited by 2
Schmidt‐Rhaesa, A. (2007) · Oxford University Press eBooks · doi:10.1093/acprof:oso/9780198566687.003.0014 · Cited by 2
Ozernyuk, N. D. (2019) · Paleontological Journal · doi:10.1134/s0031030119110078 · Cited by 1
“The issue of mesoderm formation in diploblastic metazoans prior to the emergence of ctenophores is a matter of discussion for molecular biologists and geneticists, in addition to being of interest for researchers in the field of evolutionary morphology (Peterson and Davidson, 2000).”
BackgroundPhanerozoic evolution—Ediacaran biota
Cabej, N. R. (2019) · Elsevier eBooks · doi:10.1016/b978-0-12-814311-7.00002-0 · Cited by 2
Control of few node genetic regulatory networks
Wei-Ming, Y., Bin-Bin, L. U., Chen, Z., & Di, Z. (2013) · Acta Physica Sinica · doi:10.7498/aps.62.010507 · Cited by 1
Schmidt‐Rhaesa, A. (2007) · Oxford University Press eBooks · doi:10.1093/acprof:oso/9780198566687.003.0011 · Cited by 1
Evolutionary and Ontogenetic Plasticity of Conserved Signaling Pathways in Animals’ Development
Kremnev, S. V. (2022) · Russian Journal of Developmental Biology · doi:10.1134/s1062360422020114 · Cited by 1
“However, the opinion that new taxa of animals arose due to the appearance of new genes is questioned (Peterson and Davidson, 2000; Levine and Tjian, 2003).”
Background舒, 德., & 张, 兴. (2014) · SCIENTIA SINICA Terrae · doi:10.1360/zd-2014-44-6-1155
Schmidt‐Rhaesa, A. (2007) · Oxford University Press eBooks · doi:10.1093/acprof:oso/9780198566687.003.0006 · Cited by 1
Coding Genes Helped the Origination and Diversification of Intragenic MicroRNAs
Liu, C., Zhang, X., Yuan, J., Xiang, J., & Li, F. (2025) · Molecular Biology and Evolution · doi:10.1093/molbev/msaf036 · Cited by 1
“…discrepancy between the genetic consistency and the morphological revolution, it was proposed that although the total number of coding genes did not change much, their regulation was profoundly updated, which contributed to the morphological novelties (Peterson and Davidson 2000; Valentine 2000).”
Schmidt‐Rhaesa, A. (2007) · Oxford University Press eBooks · doi:10.1093/acprof:oso/9780198566687.003.0003 · Cited by 1
Erwin, D. H. (2017) · History & Philosophy of the Life Sciences · doi:10.1007/s40656-017-0156-z · Cited by 1
“Together they applied the insights from Davidson’s articulation of types of development to the issue of the origin of animal body plans (Davidson et al. 1995; Peterson et al. 1997; Peterson et al. 2000a, b; Peterson and Davidson 2000).”
MethodEstudios funcionales comparados de la evolución de la segmentación en insectos
Esponda-Behrens, N. (2014) · doi:10.35537/10915/43085 · Cited by 1
STRUCTURE AND COMMUNICATION IN COMPLEX NETWORKS
Sneppen, K. (2006) · Springer eBooks · doi:10.1007/1-4020-5030-5_1
Krämer-Eis, A., Luca Ferretti, A., Schiffer, P. H., Heger, P., & Wiehe, T. (2016) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/041806
Schmidt‐Rhaesa, A. (2007) · Oxford University Press eBooks · doi:10.1093/acprof:oso/9780198566687.003.0002
articulating the Metameria (Metazoa, Coelomata) Coelomata) Coelomata) Coelomata) Coelomata)
Almeida, W. D. O., Christoffersen, M. L., Amorim, D. D. S., Rinaldo, A., Garraffoni, S., & Sene-Silva, G. (2003)
Krämer-Eis, A., Luca Ferretti, A., Schiffer, P. H., Heger, P., & Wiehe, T. (2016)
Development of the Central Nervous System
Catala, M. (2020) · Springer eBooks · doi:10.1007/978-3-319-72168-2_1
Contralateral premolars: Validation of symmetry
(2019) · Den norske tannlegeforenings Tidende · doi:10.56373/2019-8-8
“The bilaterian blueprint for segmental identity, anteroposterior vectorial patterning, and development of anatomical structures is encoded by conserved common cladistic regulatory genes known as homeotic genes such as Hox genes [29].”
BackgroundSchmidt‐Rhaesa, A. (2007) · Oxford University Press eBooks · doi:10.1093/acprof:oso/9780198566687.003.0013
Early Stages of Animal Mesoderm Evolution
Ozernyuk, N. D., & Isaeva, V. V. (2022) · Russian Journal of Developmental Biology · doi:10.1134/s1062360422020096
(2014) · Elsevier eBooks · doi:10.1016/b978-0-12-800165-3.00023-0
Schmidt‐Rhaesa, A. (2007) · Oxford University Press eBooks · doi:10.1093/acprof:oso/9780198566687.003.0012
Schmidt‐Rhaesa, A. (2007) · Oxford University Press eBooks · doi:10.1093/acprof:oso/9780198566687.003.0005
Schmidt‐Rhaesa, A. (2007) · Oxford University Press eBooks · doi:10.1093/acprof:oso/9780198566687.003.0008
Schmidt‐Rhaesa, A. (2007) · Oxford University Press eBooks · doi:10.1093/acprof:oso/9780198566687.003.0010
(2001) · Elsevier eBooks · doi:10.1016/b978-012205351-1.50006-9
(2007) · Oxford University Press eBooks · doi:10.1093/acprof:oso/9780198566687.002.0006
(2007) · Oxford University Press eBooks · doi:10.1093/acprof:oso/9780198566687.002.0003
(2007) · Oxford University Press eBooks · doi:10.1093/acprof:oso/9780198566687.002.0004
Fast Cycling Culture of the Marine Annelid Platynereis dumeriliiPreprint
Legras, M., Ghisleni, G., Soilihi, R., Celmar, E., & Balavoine, G. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.04.30.538804
Origins and Diversification of Marine Invertebrate Larvae
Boyle, M. J. (2025) · Elsevier eBooks · doi:10.1016/b978-0-08-102871-1.00029-4
Elucidation of the Pax/Six gene regulatory network in Ephydatia muelleri
Rued, A. C. (2012)
Pentaxonic Body Plan in Adult Living Echinoderms
Isaeva, V. V. (2025) · Paleontological Journal · doi:10.1134/s0031030125600842
“…larval axis, homologous to the ancestral AP axis of the bilaterian body and becoming the oral-aboral axis of the adult organism, the arms/rays of which turn out to be lateral appendages of the main axial pattern of the body (Peterson et al 2000; Smith, 2008; Lowe et al., 2015; Omori et al., 2018).”
InfluentialComparative Analysis of Individual Development in Sponges
Ereskovsky, A. V. (2010) · Springer eBooks · doi:10.1007/978-90-481-8575-7_6
Borings in Cloudina Shells: Complex Predator-Prey Dynamics in the Terminal Neoproterozoic
HUA, H., PRATT, B. R., & ZHANG, L.-Y. (2003) · PALAIOS · doi:10.1669/0883-1351(2003)018
Metadata
- Authors
- Peterson, K. J., & Davidson, E. H.
- Affiliations
- California Institute of Technology (US)
- Corresponding author
- Davidson, Eric H.
- ORCID
- Peterson, Kevin J.
- Venue
- Proceedings of the National Academy of Sciences
- Publisher
- National Academy of Sciences
- Published
- 2000-04-25
- Volume
- 97
- Issue
- 9
- Pages
- 4430-4433
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- PMC
- PMC34315
- OpenAlex
- W2147483153
- Cited by
- 139
- References
- 43
- Citations by year
- 2025: 4 · 2024: 2 · 2023: 4 · 2022: 3 · 2021: 1 · 2020: 3 · 2019: 8 · 2017: 1 · 2016: 4 · 2015: 4 · 2014: 4 · 2013: 4 · 2012: 4
- FWCI
- 4.58
- Type
- journal article
- Language
- en
- Open access
- green
- europepmc.org
- Locations
- Proceedings of the National Academy of Sciences (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- CaltechAUTHORS (California Institute of Technology) (submittedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Developmental Biology and Gene Regulation
- Life Sciences › Agricultural and Biological Sciences › Animal Science and Zoology › Marine Invertebrate Physiology and Ecology
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Chromosomal and Genetic Variations
- Keywords
- bilaterian origin, bilaterian evolution, transcription factor regulation, developmental gene regulation
- MeSH terms
- Animals, Embryo, Nonmammalian, Biological Evolution, Gene Expression Regulation, Genes, Homeobox, Invertebrates, Phylogeny, Transcription Factors, Body Patterning
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
