Cited by 561Physiological and biochemical adaptationsCancer, Hypoxia, and MetabolismPlant responses to water stress

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Hypoxia-induced gene expression profiling in the euryoxic fish Gillichthys mirabilis

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Gracey, Andrew Y., Troll, Joshua V., Somero, George N.·2001·Proceedings of the National Academy of Sciences

DOI 10.1073/pnas.98.4.1993PMC PMC29370

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Abstract

Hypoxia is important in both biomedical and environmental contexts and necessitates rapid adaptive changes in metabolic organization. Mammals, as air breathers, have a limited capacity to withstand sustained exposure to hypoxia. By contrast, some aquatic animals, such as certain fishes, are routinely exposed and resistant to severe environmental hypoxia. Understanding the changes in gene expression in fishes exposed to hypoxic stress could reveal novel mechanisms of tolerance that may shed new light on hypoxia and ischemia in higher vertebrates. Using cDNA microarrays, we have studied gene expression in a hypoxia-tolerant burrow-dwelling goby fish, Gillichthys mirabilis. We show that a coherent picture of a complex transcriptional response can be generated for a nonmodel organism for which sequence data were unavailable. We demonstrate that: ( i ) although certain shifts in gene expression mirror changes in mammals, novel genes are differentially expressed in fish; and ( ii ) tissue-specific patterns of expression reflect the different metabolic roles of tissues during hypoxia.

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Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction
Chomczynski, P., & Sacchi, N. (1987) · Analytical Biochemistry · doi:10.1006/abio.1987.9999 · Cited by 65,515
Cluster analysis and display of genome-wide expression patterns
Eisen, M. B., Spellman, P. T., Brown, P. O., & Botstein, D. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.25.14863 · Cited by 16,184
Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling
Alizadeh, A. A., Eisen, M. B., Davis, R. E., Ma, C., Lossos, I. S., Rosenwald, A., Boldrick, J. C., Sabet, H., Tran, T., Yu, X., et al. (2000) · Nature · doi:10.1038/35000501 · Cited by 9,925
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Suppression subtractive hybridization: a method for generating differentially regulated or tissue-specific cDNA probes and libraries.
Diatchenko, L. B., Lau, Y. C., Campbell, A. P., Chenchik, A. A., Moqadam, F., Huang, B. C. B., Lukyanov, S., Lukyanov, K. A., Gurskaya, N. G., Sverdlov, E. D., et al. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.12.6025 · Cited by 3,009
Exploring the new world of the genome with DNA microarrays
Brown, P. O., & Botstein, D. (1999) · Nature Genetics · doi:10.1038/4462 · Cited by 2,430
Systematic variation in gene expression patterns in human cancer cell lines
Ross, D. T., Scherf, U., Eisen, M. B., Perou, C. M., Rees, C., Spellman, P., Iyer, V., Jeffrey, S. S., Van de Rijn, M., Waltham, M., et al. (2000) · Nature Genetics · doi:10.1038/73432 · Cited by 2,088
Regulation of Mammalian O 2 Homeostasis by Hypoxia-Inducible Factor 1
Semenza, G. L. (1999) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev.cellbio.15.1.551 · Cited by 1,914
Transcriptional regulation of genes encoding glycolytic enzymes by hypoxia-inducible factor 1.
Semenza, G., Roth, P. H., Fang, H. M., & Wang, G. L. (1994) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)31580-6 · Cited by 1,892
HIF-1: mediator of physiological and pathophysiological responses to hypoxia
Semenza, G. L. (2000) · Journal of Applied Physiology · doi:10.1152/jappl.2000.88.4.1474 · Cited by 1,822

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Research works printed but not linked: 6

Z R Li, R Hromchak, A Mudipalli, A Bloch Cancer Res 58, 4282–4287 (1998).
T Chard Growth Regul 4, 91–100 (1994).
S Matsuda, J Kawamura-Tsuzuku, M Ohsugi, M Yoshida, M Emi, Y Nakamura, M Onda, Y Yoshida, A Nishiyama, T Yamamoto Oncogene 12, 705–713 (1996).
Y W Kim, G A Otterson, R A Kratzke, A B Coxon, F J Kaye Mol Cell Biol 14, 7256–7264 (1994).
R W Smith, D F Houlihan, G E Nilsson, J G Brechin Am J Physiol 271, R897–R904 (1996).
N M Aguilar Ph.D. thesis (Scripps Oceanographic Institute, Univ. of California, San Diego), pp. 201 (2000).

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Authors: Gracey, A. Y., Troll, J. V., & Somero, G. N.
Affiliations: Hopkins Marine Station (US)
ORCID: Gracey, Andrew Y.
Somero, George N.
Venue: Proceedings of the National Academy of Sciences
Publisher: National Academy of Sciences
Published: 2001-02-13
Volume: 98
Issue: 4
Pages: 1993-1998
ISSN: 0027-8424 (ISSN-L)
1091-6490
DOI: 10.1073/pnas.98.4.1993
PMC: PMC29370
OpenAlex: W2008308093
Cited by: 561
References: 32
Citations by year: 2026: 7 · 2025: 7 · 2024: 15 · 2023: 9 · 2022: 10 · 2021: 21 · 2020: 13 · 2019: 18 · 2018: 20 · 2017: 31 · 2016: 21 · 2015: 19 · 2014: 19 · 2013: 23 · 2012: 21
FWCI: 27.02
Type: journal article
Language: en
Open access: green
www.ncbi.nlm.nih.gov
Locations: Proceedings of the National Academy of Sciences (publishedVersion)
PubMed Central (publishedVersion)
PubMed (publishedVersion)
Topics: Physical Sciences › Environmental Science › Ecology › Physiological and biochemical adaptations
Life Sciences › Biochemistry, Genetics and Molecular Biology › Cancer Research › Cancer, Hypoxia, and Metabolism
Life Sciences › Agricultural and Biological Sciences › Plant Science › Plant responses to water stress
Keywords: hypoxia, hypoxia tolerance, Gillichthys mirabilis, gene expression profiling, transcriptional response, tissue-specific gene expression, hypoxia-ischemia
MeSH terms: Amino Acids, Animals, Hypoxia, Base Sequence, Brain, Cell Division, Glycolysis, Liver, Molecular Sequence Data, Myocardium, Oxygen, Perciformes, DNA, Complementary, Muscle, Skeletal, Gene Expression Profiling

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Hypoxia-induced gene expression profiling in the euryoxic fish Gillichthys mirabilis

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