p53 Suppresses the Activation of the Bcl-2 Promoter by the Brn-3a POU Family Transcription Factor

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Identification and Characterization of the IKKα Promoter

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The Brn-3a transcription factor inhibits the pro-apoptotic effect of p53 and enhances cell cycle arrest by differentially regulating the activity of the p53 target genes encoding Bax and p21CIP1/Waf1

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Nuclear Factor κB- and Specificity Protein 1-dependent p53-mediated Bi-directional Regulation of the Human Manganese Superoxide Dismutase Gene

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TrkA Induces Apoptosis of Neuroblastoma Cells and Does So via a p53-dependent Mechanism*[boxs]

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Brn-3a Activates the Expression of Bcl-xL and Promotes Neuronal Survival in Vivo as Well as in Vitro

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Secreted fibroblast miR-34a induces tubular cell apoptosis in fibrotic kidney

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Different effects of genistein on molecular markers related to apoptosis in two phenotypically dissimilar breast cancer cell lines

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Apoptotic index or a combination of Bax/Bcl-2 expression correlate with survival after resection of pancreatic adenocarcinoma

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DNA damage-related gene expression as biomarkers to assess cellular response after gamma irradiation of a human lymphoblastoid cell line

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BRN2 suppresses apoptosis, reprograms DNA damage repair, and is associated with a high somatic mutation burden in melanomaPreprint

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Regulation of mast cell survival and function by tuberous sclerosis complex 1

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Codon 104 variation of p53 gene provides adaptive apoptotic responses to extreme environments in mammals of the Tibet plateau

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Inhibition of UV-C Light–Induced Apoptosis in Liver Cells by 2,3,7,8-Tetrachlorodibenzo-p-Dioxin

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p53 Targets Chromatin Structure Alteration to Repress α-Fetoprotein Gene Expression

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Physical and Functional Antagonism between Tumor Suppressor Protein p53 and Fortilin, an Anti-apoptotic Protein

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Brn-3b enhances the pro-apoptotic effects of p53 but not its induction of cell cycle arrest by cooperating in trans-activation of bax expression

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Spatially and Temporally Regulated NRF2 Gene Therapy Using Mcp-1 Promoter in Retinal Ganglion Cell Injury

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Bacterial redox protein azurin induce apoptosis in human osteosarcoma U2OS cells

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Human DDA3 is an oncoprotein down-regulated by p53 and DNA damage

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The neural crest transcription factor Brn3a is expressed in melanoma and required for cell cycle progression and survival

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Redox Homeostasis Dysregulation in Noise-Induced Hearing Loss: Oxidative Stress and Antioxidant Treatment

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Key Signaling Pathways Regulate the Development and Survival of Auditory Hair Cells

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Regulation of tNOX expression through the ROS-p53-POU3F2 axis contributes to cellular responses against oxaliplatin in human colon cancer cells

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Generation of Reactive Oxygen Species by Polyenylpyrroles Derivatives Causes DNA Damage Leading to G2/M Arrest and Apoptosis in Human Oral Squamous Cell Carcinoma Cells

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POU transcription factors in melanocytes and melanoma

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Co-expression of POU4F2/Brn-3b with p53 may be important for controlling expression of pro-apoptotic genes in cardiomyocytes following ischaemic/hypoxic insults

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In Vitro and In Vivo Transfer of bcl-2 Gene into Keratinocytes Suppresses UVB-induced Apoptosis¶

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Up-regulation of Bcl-2 by redox signals in glomerular mesangial cells

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Pou4f1 and Pou4f2 Are Dispensable for the Long-Term Survival of Adult Retinal Ganglion Cells in Mice

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Identification of a novel Bcl-2 promoter region that counteracts in a p53-dependent manner the inhibitory P2 region

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Intracellular Insulin-like Growth Factor-1 Induces Bcl-2 Expression in Airway Epithelial Cells

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Pramanicin Analog Induces Apoptosis in Human Colon Cancer Cells: Critical Roles for Bcl-2, Bim, and p38 MAPK Signaling

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p53 alters intracellular Ca2+ signaling through regulation of TRPM4

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Involvement of Various Molecular Events in Cellular Injury Induced by Smokeless Tobacco

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Anti-apoptotic factor z-Val-Ala-Asp-fluoromethylketone promotes the survival of cochlear hair cells in a mouse model for human deafness

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Coexpression of Brn‐3a POU protein with p53 in a population of neuronal progenitor cells is associated with differentiation and protection against apoptosis

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Distinct promoter elements mediate the co-operative effect of Brn-3a and p53 on the p21 promoter and their antagonism on the Bax promoter

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Mechanism of action of interleukin-2 (IL-2)-Bax, an apoptosis-inducing chimaeric protein targeted against cells expressing the IL-2 receptor

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Making Connections: p53 and the Cathepsin Proteases as Co-Regulators of Cancer and Apoptosis

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CRHR1 mediates p53 transcription induced by high altitude hypoxia through ERK 1/2 signaling in rat hepatic cells

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Knockout of p53 leads to a significant increase in ALV-J replication

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p53‐mediated enhancement of radiosensitivity by selenophosphate synthetase 1 overexpression

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Local Depletion of DNA Methylation Identifies a Repressive p53 Regulatory Region in the NEK2 Promoter

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Essential but partially redundant roles for POU4F1/Brn-3a and POU4F2/Brn-3b transcription factors in the developing heart

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Stimulation-induced gene expression in Ramos B-cells

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Impact of the p53 status of tumor cells on extrinsic and intrinsic apoptosis signaling

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Cancer cell metabolism and developmental homeodomain/POU domain transcription factors: A connecting link

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The Possible Effects of Sodium Nitrite and Sodium Benzoate as Food Additives on The Liver in Male Rats

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Cardiac expression of Brn-3a and Brn-3b POU transcription factors and regulation of Hsp27 gene expression

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The Brn-3a POU family transcription factor stimulates p53 gene expression in human and mouse tumour cells

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A minimal Bcl-x promoter is activated by Brn-3a and repressed by p53

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The Brn-3a transcription factor inhibits the pro-apoptotic effect of p53 and enhances cell cycle arrest by differentially regulating the activity of the p53 target genes encoding Bax and p21CIP1/Waf1

Budhram-Mahadeo, V. S., Morris, P. J., & Latchman, D. S. (2002) · Oncogene · doi:10.1038/sj.onc.1205842 · Cited by 53 · see citing works

Distinct promoter elements mediate the co-operative effect of Brn-3a and p53 on the p21 promoter and their antagonism on the Bax promoter

Perez-Sanchez, C. (2002) · Nucleic Acids Research · doi:10.1093/nar/gkf610 · Cited by 19 · see citing works

Brn-3a Transcription Factor Blocks p53-mediated Activation of Proapoptotic Target Genes Noxa and Bax in Vitro and in Vivo to Determine Cell Fate

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