Alternative RNA Splicing Generates a Glycosylphosphatidylinositol-anchored Form of Ceruloplasmin in Mammalian Brain

Molecular cloning: A laboratory manual

Deininger, P. L. (1990) · Analytical Biochemistry · doi:10.1016/0003-2697(90)90595-z · Cited by 84,684

Hephaestin, a ceruloplasmin homologue implicated in intestinal iron transport, is defective in the sla mouse

Vulpe, C. D., Kuo, Y.-M., Murphy, T. L., Cowley, L., Askwith, C., Libina, N., Gitschier, J., & Anderson, G. J. (1999) · Nature Genetics · doi:10.1038/5979 · Cited by 1,084

Altered Brain Metabolism of Iron as a Cause of Neurodegenerative Diseases?

Gerlach, M., Ben‐Shachar, D., Riederer, P. F., & Youdim, M. B. H. (1994) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.1994.63030793.x · Cited by 704

A permease-oxidase complex involved in high-affinity iron uptake in yeast.

Stearman, R., Yuan, D. S., Yamaguchi-Iwai, Y., Klausner, R. D., & Dancis, A. (1996) · Science · doi:10.1126/science.271.5255.1552 · Cited by 683

The possible significance of the ferrous oxidase activity of ceruloplasmin in normal human serum.

Osaki, S., Johnson, D. A., & Frieden, E. (1966) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)96527-0 · Cited by 679

The FET3 gene of S. cerevisiae encodes a multicopper oxidase required for ferrous iron uptake.

Askwith, C., Eide, D., Van Ho, A., Bernard, P. S., Li, L., Davis-Kaplan, S., Sipe, D. M., & Kaplan, J. (1994) · Cell · doi:10.1016/0092-8674(94)90346-8 · Cited by 670

Aceruloplasminemia: molecular characterization of this disorder of iron metabolism.

Harris, Z. L., Takahashi, Y., Miyajima, H., Serizawa, M., MacGillivray, R. T., & Gitlin, J. D. (1995) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.92.7.2539 · Cited by 558

HOW GLYCOSYL-PHOSPHATIDYLINOSITOL-ANCHORED MEMBRANE PROTEINS ARE MADE

Udenfriend, S., & Kodukula, K. (1995) · Annual Review of Biochemistry · doi:10.1146/annurev.bi.64.070195.003023 · Cited by 485

A mutation in the ceruloplasmin gene is associated with systemic hemosiderosis in humans

Yoshida, K., Furihata, K., Takeda, S., Nakamura, A., Yamamoto, K., Morita, H., Hiyamuta, S., Ikeda, S.-I., Shimizu, N., & Yanagisawa, N. (1995) · Nature Genetics · doi:10.1038/ng0395-267 · Cited by 463

The X-ray structure of human serum ceruloplasmin at 3.1 Å: nature of the copper centres

Zaitseva, I., Zaitsev, V., Card, G. L., Ka, M., Bax, B. D., Ralph, A. C., & Lindley, P. F. (1996) · JBIC Journal of Biological Inorganic Chemistry · doi:10.1007/s007750050018 · Cited by 355

Trace elements in human physiology and pathology. Copper

Tapiero, H., Townsend, D. M., & Tew, K. D. (2003) · Biomedicine & Pharmacotherapy · doi:10.1016/s0753-3322(03)00012-x · Cited by 1,046

C ERULOPLASMIN M ETABOLISM AND F UNCTION

Hellman, N. E., & Gitlin, J. D. (2002) · Annual Review of Nutrition · doi:10.1146/annurev.nutr.22.012502.114457 · Cited by 954

Copper and iron disorders of the brain

Madsen, E., & Gitlin, J. D. (2007) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.30.051606.094232 · Cited by 557

Intracellular iron transport and storage: from molecular mechanisms to health implications

Mackenzie, E. L., Iwasaki, K., & Tsuji, Y. (2008) · Antioxidants & Redox Signaling · doi:10.1089/ars.2007.1893 · Cited by 526

Striking while the iron is hot: Iron metabolism and ferroptosis in neurodegeneration

Masaldan, S., Bush, A. I., Devos, D., Rolland, A., & Moreau, C. (2018) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2018.09.033 · Cited by 494

Ceruloplasmin regulates iron levels in the CNS and prevents free radical injury

Patel, B. N., Dunn, R. J., Jeong, S. Y., Zhu, Q., Julien, J.-P., & David, S. (2002) · The Journal of Neuroscience · doi:10.1523/jneurosci.22-15-06578.2002 · Cited by 379

Glycosylphosphatidylinositol-anchored ceruloplasmin is required for iron efflux from cells in the central nervous system

Jeong, S. Y., & David, S. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m301988200 · Cited by 377

Ceruloplasmin and other copper binding components of blood plasma and their functions: an update

Linder, M. C. (2016) · Metallomics · doi:10.1039/c6mt00103c · Cited by 327

An overview of molecular basis of iron metabolism regulation and the associated pathologies

Silva, B., & Faustino, P. (2015) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2015.03.011 · Cited by 300

Copper and Oxidative Stress in the Pathogenesis of Alzheimer’s Disease

Eskici, G., & Axelsen, P. H. (2012) · Biochemistry · doi:10.1021/bi3006169 · Cited by 291

Iron homeostasis and toxicity in retinal degeneration

He, X., Hahn, P., Iacovelli, J., Wong, R., King, C., Bhisitkul, R., Massaro-Giordano, M., & Dunaief, J. L. (2007) · Progress in Retinal and Eye Research · doi:10.1016/j.preteyeres.2007.07.004 · Cited by 260

Brain iron metabolism: Neurobiology and neurochemistry

Ke, Y., & Qian, Z. (2007) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2007.07.009 · Cited by 239

Iron and neurodegenerative disorders

Thompson, K. J., Shoham, S., & Connor, J. R. (2001) · Brain Research Bulletin · doi:10.1016/s0361-9230(01)00510-x · Cited by 235

The long history of iron in the Universe and in health and disease

Sheftel, A. D., Mason, A. B., & Ponka, P. (2011) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/j.bbagen.2011.08.002 · Cited by 244

Structure to function relationships in ceruloplasmin: a 'moonlighting' protein

Bielli, P., & Calabrese, L. (2002) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-002-8519-2 · Cited by 212

Brain Iron Homeostasis: From Molecular Mechanisms To Clinical Significance and Therapeutic Opportunities

Singh, N., Haldar, S., Tripathi, A. K., Horback, K., Wong, J., Sharma, D., Beserra, A., Suda, S., Anbalagan, C., Dev, S., et al. (2013) · Antioxidants and Redox Signaling · doi:10.1089/ars.2012.4931 · Cited by 208

Brain iron transport and neurodegeneration

Qian, Z., & Shen, X. (2001) · Trends in Molecular Medicine · doi:10.1016/s1471-4914(00)01910-9 · Cited by 196

Iron: The Redox-active Center of Oxidative Stress in Alzheimer Disease

Castellani, R. J., Moreira, P. I., Liu, G., Dobson, J., Perry, G., Smith, M. A., & Zhu, X. (2007) · Neurochemical Research · doi:10.1007/s11064-007-9360-7 · Cited by 180

Neurodegeneration with brain iron accumulation: update on pathogenic mechanisms

Levi, S., & Finazzi, D. (2014) · Frontiers in Pharmacology · doi:10.3389/fphar.2014.00099 · Cited by 164

Ceruloplasmin and what it might do

Healy, J., & Tipton, K. F. (2007) · Journal of Neural Transmission · doi:10.1007/s00702-007-0687-7 · Cited by 166

Iron transport across the blood–brain barrier: development, neurovascular regulation and cerebral amyloid angiopathy

McCarthy, R. C., & Kosman, D. J. (2014) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-014-1771-4 · Cited by 163

Mechanism of Copper Uptake from Blood Plasma Ceruloplasmin by Mammalian Cells

Ramos, D., Mar, D., Ishida, M., Vargas, R. E., Gaite, M., Montgomery, A. P., & Linder, M. C. (2016) · PLoS ONE · doi:10.1371/journal.pone.0149516 · Cited by 156

The molecular and cellular basis of copper dysregulation and its relationship with human pathologies

Maung, M. T., Carlson, A., Olea‐Flores, M., Elkhadragy, L., Schachtschneider, K. M., Navarro‐Tito, N., & Padilla‐Benavides, T. (2021) · The FASEB Journal · doi:10.1096/fj.202100273rr · Cited by 158

Ceruloplasmin in neurodegenerative diseases

Vassiliev, V. B., Harris, Z. L., & Zatta, P. F. (2005) · Brain Research Reviews · doi:10.1016/j.brainresrev.2005.03.003 · Cited by 151

Parkinson's disease: Alterations in iron and redox biology as a key to unlock therapeutic strategies

Ma, L., Azad, M. G., Dharmasivam, M., Richardson, V., Quinn, R. J., Feng, Y., Pountney, D. L., Tonissen, K. F., Mellick, G. D., Yanatori, I., et al. (2021) · Redox Biology · doi:10.1016/j.redox.2021.101896 · Cited by 151

Age-Related Changes in Iron Homeostasis and Cell Death in the Cerebellum of Ceruloplasmin-Deficient Mice

Jeong, S. Y., & David, S. (2006) · Journal of Neuroscience · doi:10.1523/jneurosci.2922-06.2006 · Cited by 149

Copper Transport and Metabolism Are Normal in Aceruloplasminemic Mice

Meyer, L. A., Durley, A. P., Prohaska, J. R., & Harris, Z. L. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m105361200 · Cited by 136

Cuprous oxidase activity of yeast Fet3p and human ceruloplasmin: implication for function

Stoj, C. S., & Kosman, D. J. (2003) · FEBS Letters · doi:10.1016/s0014-5793(03)01218-3 · Cited by 132

Dysregulation of Iron Homeostasis in the Central Nervous System and the Role of Ferroptosis in Neurodegenerative Disorders

David, S., Jhelum, P., Ryan, F., Jeong, S. Y., & Kroner, A. (2021) · Antioxidants and Redox Signaling · doi:10.1089/ars.2021.0218 · Cited by 134

Impact of Copper Limitation on Expression and Function of Multicopper Oxidases (Ferroxidases)

Prohaska, J. R. (2011) · Advances in Nutrition · doi:10.3945/an.110.000208 · Cited by 130

Brain iron homeostasis, the choroid plexus, and localization of iron transport proteins

Rouault, T. A., Zhang, D., & Jeong, S. Y. (2009) · Metabolic Brain Disease · doi:10.1007/s11011-009-9169-y · Cited by 126

Aceruloplasminemia

Miyajima, H. (2014) · Neuropathology · doi:10.1111/neup.12149 · Cited by 120

Redox Cycling in Iron Uptake, Efflux, and Trafficking

Kosman, D. J. (2010) · Journal of Biological Chemistry · doi:10.1074/jbc.r110.113217 · Cited by 127

Retinal iron homeostasis in health and disease

Song, D., & Dunaief, J. L. (2013) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2013.00024 · Cited by 122

sAPP modulates iron efflux from brain microvascular endothelial cells by stabilizing the ferrous iron exporter ferroportin

McCarthy, R. C., Park, Y., & Kosman, D. J. (2014) · EMBO Reports · doi:10.15252/embr.201338064 · Cited by 113

Ceruloplasmin gene variations and substantia nigra hyperechogenicity in Parkinson disease

Hochstrasser, H., Bauer, P., Walter, U., Behnke, S., Spiegel, J., Csoti, I., Zeiler, B., Bornemann, A., Pahnke, J., Becker, G., et al. (2004) · Neurology · doi:10.1212/01.wnl.0000144276.29988.c3 · Cited by 111

Ceruloplasmin-ferroportin system of iron traffic in vertebrates

Musci, G. (2014) · World Journal of Biological Chemistry · doi:10.4331/wjbc.v5.i2.204 · Cited by 111

Metal transporters and disease

Andrews, N. C. (2002) · Current Opinion in Chemical Biology · doi:10.1016/s1367-5931(02)00307-1 · Cited by 110

Aceruloplasminemia

Kono, S. (2013) · International review of neurobiology · doi:10.1016/b978-0-12-410502-7.00007-7 · Cited by 107

Aceruloplasminemia: new clinical, pathophysiological and therapeutic insights

Loréal, O., Turlin, B., Pigeon, C., Moisan, A., Ropert, M., Morice, P., Gandon, Y., Jouanolle, A., Vérin, M., Hider, R. C., et al. (2002) · Journal of Hepatology · doi:10.1016/s0168-8278(02)00042-9 · Cited by 106

Molecular Functions of Ceruloplasmin in Metabolic Disease Pathology

Liu, Z., Wang, M., Zhang, C., Zhou, S., & Ji, G. (2022) · Diabetes Metabolic Syndrome and Obesity · doi:10.2147/dmso.s346648 · Cited by 110

Aceruloplasminemia: A Severe Neurodegenerative Disorder Deserving an Early Diagnosis

Marchi, G., Busti, F., Zidanes, A. L., Castagna, A., & Girelli, D. (2019) · Frontiers in Neuroscience · doi:10.3389/fnins.2019.00325 · Cited by 106

Glial Cell Ceruloplasmin and Hepcidin Differentially Regulate Iron Efflux from Brain Microvascular Endothelial Cells

McCarthy, R. C., & Kosman, D. J. (2014) · PLoS ONE · doi:10.1371/journal.pone.0089003 · Cited by 103

Does Ceruloplasmin Defend Against Neurodegenerative Diseases?

Wang, B., & Wang, X. (2018) · Current Neuropharmacology · doi:10.2174/1570159x16666180508113025 · Cited by 104

Hereditary Causes of Disturbed Iron Homeostasis in the Central Nervous System

Ponka, P. (2004) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1306.022 · Cited by 99

Iron in neurodegenerative disorders

Berg, D., Becker, G., Riederer, P. F., & Rieß, O. (2002) · Neurotoxicity Research · doi:10.1080/1029842021000045444 · Cited by 98

Iron Efflux from Oligodendrocytes Is Differentially Regulated in Gray and White Matter

Schulz, K., Vulpe, C. D., Harris, Z. L., & David, S. (2011) · Journal of Neuroscience · doi:10.1523/jneurosci.2838-11.2011 · Cited by 98

Ceruloplasmin Protects Injured Spinal Cord from Iron-Mediated Oxidative Damage

Rathore, K. I., Kerr, B. J., Redensek, A., López‐Vales, R., Jeong, S. Y., Ponka, P., & David, S. (2008) · Journal of Neuroscience · doi:10.1523/jneurosci.3649-08.2008 · Cited by 98

Expression of Iron-Related Proteins at the Neurovascular Unit Supports Reduction and Reoxidation of Iron for Transport Through the Blood-Brain Barrier

Burkhart, A., Skjørringe, T., Johnsen, K. B., Siupka, P., Thomsen, L. B., Nielsen, M. S., Thomsen, L. L., & Moos, T. (2015) · Molecular Neurobiology · doi:10.1007/s12035-015-9582-7 · Cited by 98

Brain Iron Metabolism and Neurodegenerative Disorders

Sipe, J. C., Lee, P. L., & Beutler, E. (2002) · Developmental Neuroscience · doi:10.1159/000065701 · Cited by 94

Fre1p Cu2+ Reduction and Fet3p Cu1+ Oxidation Modulate Copper Toxicity in Saccharomyces cerevisiae

Shi, X., Stoj, C. S., Romeo, A. M., Kosman, D. J., & Zhu, Z. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m307019200 · Cited by 93

Brain Iron Metabolism, Redox Balance and Neurological Diseases

Gao, G., You, L., Zhang, J. J., Chang, Y., & Yu, P. (2023) · Antioxidants · doi:10.3390/antiox12061289 · Cited by 95

Ferroportin and Exocytoplasmic Ferroxidase Activity Are Required for Brain Microvascular Endothelial Cell Iron Efflux

McCarthy, R. C., & Kosman, D. J. (2013) · Journal of Biological Chemistry · doi:10.1074/jbc.m113.455428 · Cited by 93

Hepatic but not brain iron is rapidly chelated by deferasirox in aceruloplasminemia due to a novel gene mutation

Finkenstedt, A., Wolf, E., Höfner, E., Gasser, B. I., Boesch, S., Bakry, R. S., Creus, M., Kremser, C., Schocke, M., Theurl, M., et al. (2010) · Journal of Hepatology · doi:10.1016/j.jhep.2010.04.039 · Cited by 90

Biochemical Analysis of a Missense Mutation in Aceruloplasminemia

Hellman, N. E., Kono, S., Miyajima, H., & Gitlin, J. D. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m109123200 · Cited by 84

Biological effects of mutant ceruloplasmin on hepcidin-mediated internalization of ferroportin

Kono, S., Yoshida, K., Tomosugi, N., Terada, T., Hamaya, Y., Kanaoka, S., & Miyajima, H. (2010) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2010.07.011 · Cited by 85

The role of iron as a mediator of oxidative stress in Alzheimer disease

Castellani, R. J., Moreira, P. I., Perry, G. L., & Zhu, X. (2012) · BioFactors · doi:10.1002/biof.1010 · Cited by 82

Systemic iron metabolism: a review and implications for brain iron metabolism

Rouault, T. A. (2001) · Pediatric Neurology · doi:10.1016/s0887-8994(01)00260-0 · Cited by 81

Coexpression patterns indicate that GPI-anchored non-specific lipid transfer proteins are involved in accumulation of cuticular wax, suberin and sporopollenin

Edstam, M. M., Blomqvist, K., Eklöf, A., Wennergren, U., & Edqvist, J. (2013) · Plant Molecular Biology · doi:10.1007/s11103-013-0113-5 · Cited by 80

Molecular and pathological basis of aceruloplasminemia

Kono, S., & Miyajima, H. (2006) · Biological Research · doi:10.4067/s0716-97602006000100003 · Cited by 79

Microarray analysis reveals novel gene expression changes associated with erectile dysfunction in diabetic rats

Sullivan, C. J., Teal, T. H., Luttrell, I. P., Tran, K., Peters, M. A., & Wessells, H. (2005) · Physiological Genomics · doi:10.1152/physiolgenomics.00112.2005 · Cited by 76

Rethinking the role of ceruloplasmin in brain iron metabolism

Qian, Z. M., & Ke, Y. (2001) · Brain Research Reviews · doi:10.1016/s0165-0173(01)00056-x · Cited by 76

Iron and ageing: an introduction to iron regulatory mechanisms

Levenson, C. W., & Tassabehji, N. M. (2004) · Ageing Research Reviews · doi:10.1016/j.arr.2004.03.001 · Cited by 74

The copper-iron connection: Hereditary aceruloplasminemia

Nittis, T., & Gitlin, J. D. (2002) · Seminars in Hematology · doi:10.1053/shem.2002.35633 · Cited by 74

Immune cells and hepatocytes express glycosylphosphatidylinositol-anchored ceruloplasmin at their cell surface

Marques, L., Auriac, A., Willemetz, A., Banha, J., Silva, B. D. R., Canonne‐Hergaux, F., & Costa, L. M. G. (2011) · Blood Cells Molecules and Diseases · doi:10.1016/j.bcmd.2011.11.005 · Cited by 73

The ferroportin-ceruloplasmin system and the mammalian iron homeostasis machine: regulatory pathways and the role of lactoferrin

di Patti, M. C. B., Cutone, A., Polticelli, F., Rosa, L., Lepanto, M. S., Valenti, P., & Musci, G. (2018) · BioMetals · doi:10.1007/s10534-018-0087-5 · Cited by 66

Effects of development and iron status on ceruloplasmin expression in rat brain

Chang, Y. Z., Qian, Z., Wang, K., Zhu, L., Yang, X. D., Du, J. R., Jiang, L. H., Ho, K. P., Wang, Q., & Ke, Y. (2005) · Journal of Cellular Physiology · doi:10.1002/jcp.20321 · Cited by 64

Anemia and iron overload due to compound heterozygosity for novel ceruloplasmin mutations

Bosio, S., Gobbi, M. D., Roetto, A., Zecchina, G., Leonardo, E., Rizzetto, M., Lucetti, C., Petrozzi, L., Bonuccelli, U., & Camaschella, C. (2002) · Blood · doi:10.1182/blood-2002-02-0584 · Cited by 63

Hephaestin and Ceruloplasmin Play Distinct but Interrelated Roles in Iron Homeostasis in Mouse Brain

Jiang, R., Hua, C., Wan, Y., Jiang, B., Hu, H., Zheng, J., Fuqua, B. K., Dunaief, J. L., Anderson, G. J., David, S., et al. (2015) · Journal of Nutrition · doi:10.3945/jn.114.207316 · Cited by 60

Silver Ions as a Tool for Understanding Different Aspects of Copper Metabolism

Puchkova, L. V., Broggini, M., Polishchuk, E. V., Ilyechova, E. Y., & Polishchuk, R. (2019) · Nutrients · doi:10.3390/nu11061364 · Cited by 57

Iron gene expression profile in atherogenic Mox macrophages

Marques, L., Nègre‐Salvayre, A., Costa, L. M. G., & Canonne‐Hergaux, F. (2016) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2016.03.004 · Cited by 62

Analysis of the human hephaestin gene and protein: comparative modelling of the N-terminus ecto-domain based upon ceruloplasmin

Syed, B. A., Beaumont, N. J., Patel, A., Naylor, C. E., Bayele, H. K., Joannou, C. L., Rowe, P. S., Evans, R. W., & Srai, S. K. (2002) · Protein Engineering Design and Selection · doi:10.1093/protein/15.3.205 · Cited by 59

Hepatic Iron Overload Associated With a Decreased Serum Ceruloplasmin Level in a Novel Clinical Type of Aceruloplasminemia

Kono, S., Suzuki, H., Takahashi, K., Takahashi, Y., Shirakawa, K., Murakawa, Y., Yamaguchi, S., & Miyajima, H. (2006) · Gastroenterology · doi:10.1053/j.gastro.2006.04.017 · Cited by 58

Ceruloplasmin replacement therapy ameliorates neurological symptoms in a preclinical model of aceruloplasminemia

Zanardi, A., Conti, A., Cremonesi, M., D’Adamo, P., Gilberti, E., Apostoli, P., Cannistraci, C. V., Piperno, A., David, S., & Alessio, M. (2017) · EMBO Molecular Medicine · doi:10.15252/emmm.201708361 · Cited by 59

Brain Ceruloplasmin Expression After Experimental Intracerebral Hemorrhage and Protection Against Iron-Induced Brain Injury

Liu, H., Hua, Y., Keep, R. F., & Xi, G. (2018) · Translational Stroke Research · doi:10.1007/s12975-018-0669-0 · Cited by 57

Glycosylphosphatidylinositol-linked ceruloplasmin is expressed in multiple rodent organs and is lower following dietary copper deficiency

Mostad, E., & Prohaska, J. R. (2011) · Experimental Biology and Medicine · doi:10.1258/ebm.2010.010256 · Cited by 56

Development and iron‐dependent expression of hephaestin in different brain regions of rats

Qian, Z., Chang, Y., Zhu, L., Yang, L., Du, J., Ho, K., Wang, Q. L., Li, L., Wang, C., Ge, X., et al. (2007) · Journal of Cellular Biochemistry · doi:10.1002/jcb.21352 · Cited by 55

Ceruloplasmin expression by human peripheral blood lymphocytes: A new link between immunity and iron metabolism

Banha, J., Marques, L., Oliveira, R., Martins, M. D. F., Paixão, E., Pereira, D., Malhó, R., Penque, D., & Costa, L. M. G. (2007) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2007.10.032 · Cited by 53

Ceruloplasmin Plays a Neuroprotective Role in Cerebral Ischemia

Ryan, F., Zarruk, J. G., Lößlein, L., & David, S. (2019) · Frontiers in Neuroscience · doi:10.3389/fnins.2018.00988 · Cited by 53

Looking for a partner: ceruloplasmin in protein–protein interactions

Vasilyev, V. B. (2019) · BioMetals · doi:10.1007/s10534-019-00189-1 · Cited by 54

Overdosing on iron: Elevated iron and degenerative brain disorders

D’Mello, S. R., & Kindy, M. S. (2020) · Experimental Biology and Medicine · doi:10.1177/1535370220953065 · Cited by 49

Role of copper in the process of spermatogenesis

Ogórek, M., Gąsior, Ł., Pierzchała, O., Daszkiewicz, R., & Lenartowicz, M. (2017) · Postępy Higieny i Medycyny Doświadczalnej · doi:10.5604/01.3001.0010.3846 · Cited by 50

Copper Metabolism of Newborns Is Adapted to Milk Ceruloplasmin as a Nutritive Source of Copper: Overview of the Current Data

Puchkova, L. V., Babich, P. S., Zatulovskaia, Y. A., Ilyechova, E. Y., & Sole, F. D. (2018) · Nutrients · doi:10.3390/nu10111591 · Cited by 47

Iron metabolism in the eye: A review

Goralska, M., Ferrell, J., Harned, J., Lall, M. M., Nagar, S., Fleisher, L. N., & McGahan, M. C. (2008) · Experimental Eye Research · doi:10.1016/j.exer.2008.10.026 · Cited by 49

Expression of a membrane‐bound form of the ferroxidase ceruloplasmin by leptomeningeal cells

Mittal, B., Doroudchi, M. M., Jeong, S. Y., Patel, B. N., & David, S. (2003) · Glia · doi:10.1002/glia.10158 · Cited by 47

Genetic and Clinical Heterogeneity in Thirteen New Cases with Aceruloplasminemia. Atypical Anemia as a Clue for an Early Diagnosis

Cuenca, M. V., Marchi, G., Barqué, A., Esteban-Jurado, C., Marchetto, A., Giorgetti, A., Chelban, V., Houlden, H., Wood, N. W., Piubelli, C., et al. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21072374 · Cited by 45

The Effect of Ceruloplasmin on Iron Release from Placental (BeWo) Cells; Evidence for an Endogenous Cu Oxidase

Danzeisen, R., Ponnambalam, S., Lea, R. G., Page, K., Gambling, L., & McArdle, H. J. (2000) · Placenta · doi:10.1053/plac.2000.0582 · Cited by 47

Schwann Cells Provide Iron to Axonal Mitochondria and Its Role in Nerve Regeneration

Mietto, B. S., Jhelum, P., Schulz, K., & David, S. (2021) · Journal of Neuroscience · doi:10.1523/jneurosci.0900-21.2021 · Cited by 45

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Wiggins, J. E., Goyal, M., Wharram, B. L., & Wiggins, R. C. (2006) · Journal of the American Society of Nephrology · doi:10.1681/asn.2005111239 · Cited by 44

Ceruloplasmin Alters the Tissue Disposition and Neurotoxicity of Manganese, but not its Loading onto Transferrin

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Dominant Mutants of Ceruloplasmin Impair the Copper Loading Machinery in Aceruloplasminemia

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Ferroptosis in Neurological Disease

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Molecular Regulation of Copper Homeostasis in the Male Gonad during the Process of Spermatogenesis

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FET3P, ceruloplasmin, and the role of copper in iron metabolism

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The Features of Copper Metabolism in the Rat Liver during Development

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Brain Iron Metabolism and Regulation

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Interleukin-1β up-regulates iron efflux in rat C6 glioma cells through modulation of ceruloplasmin and ferroportin-1 synthesis

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Characterization of the ceruloplasmin gene and its potential role as an indirect marker for selection to Aeromonas hydrophila resistance in rohu, Labeo rohita

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Parallels and contrasts between iron and copper metabolism

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Gene expression of D-amino acid oxidase in cultured rat astrocytes: regional and cell type specific expression

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Ceruloplasmin : novel form and function in the central nervous system

Patel, B. N. (2000) · eScholarship@McGill (McGill) · doi:10.82308/14357

A Novel Glycosylphosphatidylinositol-anchored Form of Ceruloplasmin Is Expressed by Mammalian Astrocytes

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Role of ceruloplasmin in maintaining iron homeostasis in the CNS

Jeong, S. Y. (2002) · eScholarship@McGill (McGill) · doi:10.82308/15716

Glycosylphosphatidylinositol-anchored ceruloplasmin is required for iron efflux from cells in the central nervous system

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Expression of the ceruloplasmin gene in the human retina and brain: implications for a pathogenic model in aceruloplasminemia

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