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A Protective Role of the Low Density Lipoprotein Receptor-related Protein against Amyloid β-Protein Toxicity*
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These effects were blocked by exogenous administration of RAP and are dependent on calcium/calmodulin-dependent kinase 2 signaling.
“These effects were blocked by exogenous administration of RAP and are dependent on calcium/calmodulin-dependent kinase 2 signaling (Van Uden et al., 2000).”
From Increased Extracellular Amyloid Deposition and Neurodegeneration in Human Amyloid Precursor Protein Transgenic Mice Deficient in Receptor-Associated Protein (2002) · cites this paper as Van Uden et al., 2000
In the presence of α2M, LRP protects neural cell lines against the neurotoxic effects of Aβ.
“In addition, previous studies have shown that, in the presence of ␣2M, LRP protects neural cell lines against the neurotoxic effects of A (Fabrizi et al., 1999;Van Uden et al., 1999b, 2000).”
From Increased Extracellular Amyloid Deposition and Neurodegeneration in Human Amyloid Precursor Protein Transgenic Mice Deficient in Receptor-Associated Protein (2002) · cites this paper as Van Uden et al., 2000
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An essential role for postsynaptic calmodulin and protein kinase activity in long-term potentiation
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Shinohara, M., Tachibana, M., Kanekiyo, T., & Bu, G. (2017) · Journal of Lipid Research · doi:10.1194/jlr.r075796 · Cited by 297
Zerbinatti, C. V., Wozniak, D. F., Cirrito, J., Cam, J. A., Osaka, H., Bales, K. R., Zhuo, M., Paul, S. M., Holtzman, D. M., & Bu, G. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0305803101 · Cited by 133
Functional Roles of the Interaction of APP and Lipoprotein Receptors
Pohlkamp, T., Wasser, C. R., & Herz, J. (2017) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2017.00054 · Cited by 92
Van Uden, E., Mallory, M., Veinbergs, I., Alford, M., Rockenstein, E., & Masliah, E. (2002) · The Journal of Neuroscience · doi:10.1523/jneurosci.22-21-09298.2002 · Cited by 91
Self-citation
Metadata
- Authors
- Van Uden, E., Sagara, Y., Van Uden, J., Orlando, R., Mallory, M., Rockenstein, E., & Masliah, E.
- Venue
- Journal of Biological Chemistry
- Publisher
- Elsevier BV
- Published
- 2000-09
- Volume
- 275
- Issue
- 39
- Pages
- 30525-30530
- ISSN
- 0021-9258
- Cited by
- 35
- References
- 1
- Language
- en
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