Receptor Activator of NF-κB and Osteoprotegerin Expression by Human Microvascular Endothelial Cells, Regulation by Inflammatory Cytokines, and Role in Human Osteoclastogenesis

Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation.

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Osteoprotegerin: a novel secreted protein involved in the regulation of bone density.

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Osteoclast differentiation factor is a ligand for osteoprotegerin/osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKL

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OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph node organogenesis.

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Osteoprotegerin-deficient mice develop early onset osteoporosis and arterial calcification.

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Modulation of Osteoclast Differentiation and Function by the New Members of the Tumor Necrosis Factor Receptor and Ligand Families

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Endothelial cells in physiology and in the pathophysiology of vascular disorders.

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VEGF couples hypertrophic cartilage remodeling, ossification and angiogenesis during endochondral bone formation

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Tumor necrosis factor receptor family member RANK mediates osteoclast differentiation and activation induced by osteoprotegerin ligand.

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Identity of Osteoclastogenesis Inhibitory Factor (OCIF) and Osteoprotegerin (OPG): A Mechanism by which OPG/OCIF Inhibits Osteoclastogenesis in Vitro1

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Osteoprotegerin Enhances Osteogenesis of Human Mesenchymal Stem Cells

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The miR‐155‐5p inhibits osteoclast differentiation through targeting CXCR2 in orthodontic root resorption

Jiang, H., Kitaura, H., Liu, L., Mizoguchi, I., & Liu, S. (2021) · Journal of Periodontal Research · doi:10.1111/jre.12875 · Cited by 28

Osteoprotegerin Causes Apoptosis of Endothelial Progenitor Cells by Induction of Oxidative Stress

Kim, J., Park, Y., Kim, K., Choi, J., Kim, W., & Cho, C. (2013) · Arthritis & Rheumatism · doi:10.1002/art.37997 · Cited by 28

Human polymorphonuclear neutrophils express RANK and are activated by its ligand, RANKL

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The association between carotid or femoral atherosclerosis and low bone mass in postmenopausal women referred for osteoporosis screening. Does osteoprotegerin play a role?

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Possible Role of Osteoprotegerin and Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand as Markers of Plaque Instability in Coronary Artery Disease

Shaker, O. G., El‐Shehaby, A., & Nabih, M. I. (2010) · Angiology · doi:10.1177/0003319710370961 · Cited by 27

An advanced tri‐culture model to evaluate the dynamic interplay among osteoblasts, osteoclasts, and endothelial cells

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Reactive Oxygen Species Control Osteoblast Apoptosis through SIRT1/PGC-1α/P53 Lys382 Signaling, Mediating the Onset of Cd-Induced Osteoporosis

Ran, D., Zhou, D., Liu, G., Ma, Y., Ali, W., Yu, R., Wang, Q., Zhao, H., Zhu, J., Zou, H., et al. (2023) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.2c08505 · Cited by 25

Comparative effects of metformin and pioglitazone on fetuin-A and osteoprotegerin concentrations in patients with newly diagnosed diabetes: A randomized clinical trial

Esteghamati, A., Afarideh, M., Feyzi, S., Noshad, S., & Nakhjavani, M. (2014) · Diabetes & Metabolic Syndrome Clinical Research & Reviews · doi:10.1016/j.dsx.2014.09.009 · Cited by 26

Biomarkers Associated with Vascular Calcification in Peritoneal Dialysis

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Intima-media thickness of the carotid arteries is related to serum osteoprotegerin levels in healthy postmenopausal women

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Evidence of a role for RANKL in the development of myeloma bone disease

DELEENHEER, E. (2004) · Current Opinion in Pharmacology · doi:10.1016/j.coph.2004.03.011 · Cited by 26

Prevention of bone mineral density loss in patients with rheumatoid arthritis treated with anti-TNFα therapy

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Osteostat/Tumor Necrosis Factor Superfamily 18 Inhibits Osteoclastogenesis and Is Selectively Expressed by Vascular Endothelial Cells

Nardelli, B., Zaritskaya, L., McAuliffe, W. J., Ni, Y., Lincoln, C., Cho, Y. H., Birse, C. E., Halpern, W., Ullrich, S. J., & Moore, P. A. (2005) · Endocrinology · doi:10.1210/en.2005-0518 · Cited by 24

Epidermal Growth Factor in Liposomes May Enhance Osteoclast Recruitment during Tooth Movement in Rats

Saddi, K. R. G. C., Alves, G. D., Paulino, T. P., Ciancaglini, P., & Alves, J. B. (2008) · The Angle Orthodontist · doi:10.2319/0003-3219(2008)078[0604:egfilm]2.0.co;2 · Cited by 24

Osteoprotegerin protects endothelial cells against apoptotic cell death induced byPorphyromonas gingivaliscysteine proteinases

Kobayashi‐Sakamoto, M., Hirose, K., Nishikata, M., Isogai, E., & Chiba, I. (2006) · FEMS Microbiology Letters · doi:10.1111/j.1574-6968.2006.00458.x · Cited by 24

Inflammatory cells and bone loss in rheumatoid arthritis

Haynes, D. R. (2007) · Arthritis Research & Therapy · doi:10.1186/ar2213 · Cited by 24

RANKL immunisation inhibits prostate cancer metastasis by modulating EMT through a RANKL-dependent pathway

Park, M., Cho, Y. J., Kim, B., Ko, Y. J., Jang, Y., Moon, Y. H., Hyun, H., & Lim, W. (2021) · Scientific Reports · doi:10.1038/s41598-021-91721-2 · Cited by 23

Cystic Bone Angiomatosis: A Case Report Treated with Aminobisphosphonates and Review of the Literature

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Combination gene therapy targeting on interleukin-1β and RANKL for wear debris-induced aseptic loosening

Wang, H., Jia, T.-H., Zacharias, N., Gong, W., Du, H.-X., Wooley, P. H., & Yang, S.-Y. (2012) · Gene Therapy · doi:10.1038/gt.2012.1 · Cited by 23

Efficacy and safety of the anti-TNF biologic agents

Weaver, A. L. (2004) · Modern Rheumatology · doi:10.1007/s10165-004-0275-8 · Cited by 23

Parathyroid hormone decreases endothelial osteoprotegerin secretion: role of protein kinase A and C

Rashid, G., Plotkin, E., Klein, O., Green, J., Bernheim, J., & Benchetrit, S. (2008) · American Journal of Physiology-Renal Physiology · doi:10.1152/ajprenal.00622.2007 · Cited by 23

Can osteoprotegerin be used to identify the presence and severity of coronary artery disease in different clinical settings?

Hosbond, S. E., Diederichsen, A. C. P., Saaby, L., Rasmussen, L. M., Lambrechtsen, J., Munkholm, H., Sand, N. P. R., Gerke, O., Poulsen, T. S., & Mickley, H. (2014) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2014.07.013 · Cited by 22

A dominant function of p38 mitogen‐activated protein kinase signaling in receptor activator of nuclear factor‐κB ligand expression and osteoclastogenesis induction by Aggregatibacter actinomycetemcomitans and Escherichia coli lipopolysaccharide

Rossa, C., Liu, M., & Kirkwood, K. L. (2007) · Journal of Periodontal Research · doi:10.1111/j.1600-0765.2007.01013.x · Cited by 22

A single nucleotide polymorphism in the promoter region of the osteoprotegerin gene is related to intima‐media thickness of the carotid artery in hypertensive patients. The Swedish irbesartan left ventricular hypertrophy investigation vs atenolol (SILVHIA)

Brändström, H., Stiger, F., Kahan, T., Melhus, H., Nyström, F. H., Öhman, K. P., Malmqvist, K. K., Lind, L., & Kindmark, A. (2004) · Blood Pressure · doi:10.1080/08037050410035563 · Cited by 22

Lack of Observed Association between High Plasma Osteoprotegerin Concentrations and Ischemic Stroke Risk in a Healthy Population

Nybo, M., Johnsen, S. P., Dethlefsen, C., Overvad, K., Tjønneland, A. M., Jørgensen, J. O. L., & Rasmussen, L. M. (2008) · Clinical Chemistry · doi:10.1373/clinchem.2008.110593 · Cited by 22

Association of serum osteoprotegerin with ankle-brachial index and urine albumin: Creatinine ratio in African-Americans and non-Hispanic whites

Ali, Z., Ellington, A. A., Mosley, T. H., & Kullo, I. J. (2009) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2009.03.032 · Cited by 21

Serum RANKL, osteoprotegerin (OPG) and RANKL/OPG ratio in children with systemic lupus erythematosus

Ali, R. A. H., Hammad, A. M., El-Nahrery, E. M. A., Hamdy, N., El-Hawary, A. K., & Eid, R. (2019) · Lupus · doi:10.1177/0961203319867129 · Cited by 21

Plasma osteoprotegerin concentrations in peripheral sensory neuropathy in Type 1 and Type 2 diabetic patients

Nybo, M., Poulsen, M. K., Grauslund, J., Henriksen, J. E., & Rasmussen, L. M. (2010) · Diabetic Medicine · doi:10.1111/j.1464-5491.2010.02940.x · Cited by 21

Correlation of plasma osteoprotegerin (OPG) and receptor activator of the nuclear factor κB ligand (RANKL) levels with clinical risk factors in patients with advanced carotid atherosclerosis

Giaginis, C., Papadopouli, A. E., Zira, A. N., Katsargyris, Α., Klonaris, C., & Theocharis, S. E. (2012) · Medical Science Monitor · doi:10.12659/msm.883485 · Cited by 20

Serum levels of the osteoprotegerin, receptor activator of nuclear factor κ-B ligand, metalloproteinase-1 (MMP-1) and tissue inhibitors of MMP-1 levels are increased in men 6 months after acute myocardial infarction

Halapas, A., Zacharoulis, A., Theocharis, S. E., Karavidas, A. I., Korres, D. S., Papadopoulos, K., Katopodis, H., Stavropoulou, A., Lembessis, P., Xiromeritis, C., et al. (2008) · Clinical Chemistry and Laboratory Medicine (CCLM) · doi:10.1515/cclm.2008.091 · Cited by 20

Osteoprotegerin and receptor activator of nuclear factor‐κB ligand system in the early post‐operative period of liver transplantation

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Perspective on the Osteoclast

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Effect of Cytosolic Phospholipase A2 on Proinflammatory Cytokine-induced Bone Resorptive Genes Including Receptor Activator of Nuclear Factor Kappa B Ligand in Human Dental Pulp Cells

Kim, Y. S., Min, K., Lee, H.-D., Oh, H., & Kim, E.-C. (2010) · Journal of Endodontics · doi:10.1016/j.joen.2009.12.009 · Cited by 19

High oxygen tension prolongs the survival of osteoclast precursors via macrophage colony-stimulating factor

Yamasaki, N., Tsuboi, H., Hirao, M., Nampei, A., Yoshikawa, H., & Hashi­moto, J. (2008) · Bone · doi:10.1016/j.bone.2008.09.015 · Cited by 20

Inflammatory bowel diseases as secondary causes of osteoporosis

Bernstein, C. N. (2006) · Current Osteoporosis Reports · doi:10.1007/bf02686956 · Cited by 20

Differentiating the New Rheumatoid Arthritis Biologic Therapies

Weaver, A. L. (2003) · JCR Journal of Clinical Rheumatology · doi:10.1097/01.rhu.0000062513.64012.1d · Cited by 20

Review: Endothelial cell dysfunction, medial arterial calcification and osteoprotegerin in diabetes

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Pepstatin A, an Aspartic Proteinase Inhibitor, Suppresses RANKL-Induced Osteoclast Differentiation

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Receptor Activator of Nuclear Factor-κB Ligand (RANKL) and Its Relationship to Coronary Atherosclerosis in HIV Patients

Hwang, J. J., Wei, J., Abbara, S., Grinspoon, S. K., & Lo, J. (2012) · JAIDS Journal of Acquired Immune Deficiency Syndromes · doi:10.1097/qai.0b013e31826a6c16 · Cited by 19

Inflammatory, Metabolic, and Coagulation Effects on Medial Arterial Calcification in Patients with Peripheral Arterial Disease

Starčević, J. N., & Šabović, M. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24043132 · Cited by 19

The influence of geranylgeraniol on human oral keratinocytes after bisphosphonate treatment: An in vitro study

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Immunopathologie de la polyarthrite rhumatoïde

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New Insights to the Crosstalk between Vascular and Bone Tissue in Chronic Kidney Disease–Mineral and Bone Disorder

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Radiographic Evaluation of Frontal Sinus Dimensions and Anatomic Variations

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The Role of the Osteoprotegerin/RANKL/RANK System in Diabetic Vascular Disease

Grigoropoulou, P., Eleftheriadou, I., Zoupas, C., & Tentolouris, N. (2011) · Current Medicinal Chemistry · doi:10.2174/092986711797535281 · Cited by 18

Circulating Leptin and Osteoprotegerin Levels Affect Insulin Resistance in Healthy Premenopausal Obese Women

Ugur‐Altun, B., & Altun, A. (2007) · Archives of Medical Research · doi:10.1016/j.arcmed.2007.04.013 · Cited by 18

Glyburide inhibits the bone resorption induced by traumatic occlusion in rats

Arita, Y., Yoshinaga, Y., Kaneko, T., Kawahara, Y., Nakamura, K., Ohgi, K., Arita, S., Ryu, T., Takase, M., & Sakagami, R. (2020) · Journal of Periodontal Research · doi:10.1111/jre.12731 · Cited by 17

Interaction between Treg Apoptosis Pathways, Treg Function and HLA Risk Evolves during Type 1 Diabetes Pathogenesis

Glišić, S., & Jailwala, P. (2012) · PLoS ONE · doi:10.1371/journal.pone.0036040 · Cited by 17

Bone metabolism regulators and arterial stiffness in postmenopausal women

Albu, A., Fodor, D., Bondor, C. I., & Craciun, A. M. (2013) · Maturitas · doi:10.1016/j.maturitas.2013.07.001 · Cited by 17

Prediction of subclinical atherosclerosis by serum osteoprotegerin in premenopausal women with systemic lupus erythematous: correlation of osteoprotegerin with monocyte chemotactic protein-1

Park, Y., Shin, Y.-J., Kim, W.-U., & Cs, C. (2014) · Lupus · doi:10.1177/0961203313517151 · Cited by 17

The Role of Osteoprotegerin as a Cardioprotective Versus Reactive Inflammatory Marker: the Chicken or the Egg Paradox

Özkalaycı, F., Gülmez, Ö., Ugur‐Altun, B., Pandi-Perumal, S. R., & Altun, A. (2018) · Balkan Medical Journal · doi:10.4274/balkanmedj.2018.0579 · Cited by 17

Circulating osteoprotegerin is associated with age and systolic blood pressure, but not with lipid profile or fasting glucose, in postmenopausal women

Uemura, H., Yasui, T., Miyatani, Y., Yamada, M., Hiyoshi, M., Arisawa, K., & Irahara, M. (2007) · Menopause The Journal of The North American Menopause Society · doi:10.1097/gme.0b013e318046369b · Cited by 17

Endothelial cell reaction on a biological material

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Osteoclast: Origin and Differentiation

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Osteoprotegerin in pregnant adolescents differs by race and is related to infant birth weight z-score

Essley, B. V., McNanley, T. J., Cooper, B. E., McIntyre, A. W., Witter, F. R., Harris, Z. L., & O'Brien, K. O. (2011) · Journal of Developmental Origins of Health and Disease · doi:10.1017/s2040174411000511 · Cited by 16

Urinary osteoprotegerin: a potential biomarker of lupus nephritis disease activity

Gupta, R., Aggarwal, A., Sinha, S. K., Rajasekhar, L., Yadav, A., Gaur, P., Misra, R., & Negi, V. S. (2016) · Lupus · doi:10.1177/0961203316636470 · Cited by 16

Serum osteoprotegrin (OPG) in subclinical atherosclerosis in systemic lupus erythematosus

Kiani, A. N., Aukrust, P., Ueland, T., Hollan, I., Barr, E., Magder, L. S., & Petri, M. (2016) · Lupus · doi:10.1177/0961203316682101 · Cited by 16

The imbalance between osteoprotegerin and cathepsin K in the serum of patients with longstanding rheumatoid arthritis

Skoumal, M., Haberhauer, G., Kolarz, G., Hawa, G., Woloszczuk, W., Klingler, A., Varga, F., & Klaus Klaushofer, A. (2007) · Rheumatology International · doi:10.1007/s00296-007-0506-3 · Cited by 16

The effect of exercise on osteoprotegerin and TNF‐related apoptosis‐inducing ligand in obese patients

Davenport, C., Kenny, H., Ashley, D. T., O’Sullivan, E. P., Smith, D., & O’Gorman, D. J. (2012) · European Journal of Clinical Investigation · doi:10.1111/j.1365-2362.2012.02703.x · Cited by 15

Unbalanced Vitreous Levels of Osteoprotegerin, RANKL, RANK, and TRAIL in Proliferative Diabetic Retinopathy

El‐Asrar, A. M. A., Ahmad, A., Alam, K., Bittoun, E., Siddiquei, M. M., Mohammad, G., Mousa, A., Hertogh, G. D., & Opdenakker, G. (2017) · Ocular Immunology and Inflammation · doi:10.1080/09273948.2017.1343855 · Cited by 15

Osteoclasts at Bone Remodeling: Order from Order

Takito, J., & Nonaka, N. (2023) · Results and problems in cell differentiation · doi:10.1007/978-3-031-37936-9_12 · Cited by 14

Identifying coronary artery disease in men with type 2 diabetes

Davenport, C., Ashley, D. T., O’Sullivan, E. P., Corley, B., Fitzgerald, P., Agha, A., Thompson, C. J., O’Gorman, D. J., & Smith, D. (2011) · Journal of Hypertension · doi:10.1097/hjh.0b013e32834c1e95 · Cited by 13

Mitogen‐activated protein kinases mediate interleukin‐1β‐induced receptor activator of nuclear factor‐κB ligand expression in human periodontal ligament cells

Oikawa, A., Kobayashi, M., Okamatsu, Y., Shinki, T., Kamijo, R., Yamamoto, M., & Hasegawa, K. (2007) · Journal of Periodontal Research · doi:10.1111/j.1600-0765.2006.00959.x · Cited by 13

On the biology of the bony otic capsule and the pathogenesis of otosclerosis.

Bloch, S. L. (2012) · PubMed · Cited by 13

Omega 3 fatty acids effect on the vascular calcification biomarkers fetuin A and osteoprotegerin in hemodialysis patients

Werida, R. H., Abou-Madawy, S., Abdelsalam, M. S., & Helmy, M. W. (2021) · Clinical and Experimental Medicine · doi:10.1007/s10238-021-00740-w · Cited by 12

Serum Levels of IL-6, IL-10, IL-12, IL-17 and IFN-γ and Their Association with Markers of Bone Metabolism in Vitamin D-Deficient Female Students

Jamali, Z., Arababadi, M. K., & Asadikaram, G. (2012) · Inflammation · doi:10.1007/s10753-012-9531-9 · Cited by 12

Effects of RANKL Knockdown by Virus-like Particle-Mediated RNAi in a Rat Model of Osteoporosis

Hoffmann, D. B., Gruber, J., Böker, K. O., Deppe, D., Sehmisch, S., Schilling, A. F., Lemus-Diaz, N., Komrakova, M., & Schneider, S. (2018) · Molecular Therapy — Nucleic Acids · doi:10.1016/j.omtn.2018.06.001 · Cited by 12

Histone methyltransferase SETDB1 promotes osteogenic differentiation in osteoporosis by activating OTX2-mediated BMP-Smad and Wnt/β-catenin pathways

Hu, L., Cheng, Z., Wu, L., Luo, L., Ping, P., Li, S., Jia, Q., Yang, N., & Xu, B. (2023) · Human Cell · doi:10.1007/s13577-023-00902-w · Cited by 12

Circulating osteoprotegerin levels are elevated and correlated with antiphospholipid antibodies in patients with systemic lupus erythematosus

Kwok, S.-K., Shin, Y., Kim, H., Kim, H. S., Kim, J., Yoo, S., Choi, J., Kim, W., & Cs, C. (2009) · Lupus · doi:10.1177/0961203308094819 · Cited by 12

Effects of vascular endothelial growth factor (VEGF-A) and endostatin on bone

Sipola, A. (2009) · Cited by 12

Osteoprotegerin, but Not Receptor Activator for Nuclear Factor-κB Ligand, is Associated With Subclinical Coronary Atherosclerosis in HIV-Infected Men

Ketlogetswe, K. S., McKibben, R. A., Jacobson, L. P., Li, X., Dobs, A. S., Budoff, M. J., Witt, M. D., Palella, F. J., Kingsley, L., Margolick, J. B., et al. (2015) · JAIDS Journal of Acquired Immune Deficiency Syndromes · doi:10.1097/qai.0000000000000725 · Cited by 11

The increased expression of receptor activator of nuclear‐κB ligand (RANKL) of multiple myeloma bone marrow stromal cells is inhibited by the bisphosphonate ibandronate

Fernández, M., Pino, A. M., Figueroa, P., & Rodríguez, J. P. (2010) · Journal of Cellular Biochemistry · doi:10.1002/jcb.22676 · Cited by 11

Low extracellular Ca2+: a mediator of endothelial inflammation

Talmor‐Barkan, Y., Rashid, G., Weintal, I., Green, J., Bernheim, J., & Benchetrit, S. (2009) · Nephrology Dialysis Transplantation · doi:10.1093/ndt/gfp354 · Cited by 11

The association of bone turnover markers with pro- and anti-inflammatory adipokines in patients with gestational diabetes

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From bones to blood pressure, developing novel biologic approaches targeting the osteoprotegein pathway for pulmonary vascular disease

Dawson, S., & Lawrie, A. (2016) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2016.06.017 · Cited by 11

Deficiency of P‐selectin glycoprotein ligand‐1 is protective against the prothrombotic effects of interleukin‐1β

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Elevated serum osteoprotegerin levels predict in-hospital major adverse cardiac events in patients with ST elevation myocardial infarction

Çanğa, A., Durakoğlugil, M. E., Erdoğan, T., Kırbaş, A., Yılmaz, A., Çiçek, Y., Ergül, E., Çetın, M., & Kocaman, S. A. (2012) · Journal of Cardiology · doi:10.1016/j.jjcc.2012.05.010 · Cited by 10

RANKL Inhibits the Production of Osteoprotegerin from Smooth Muscle Cells under Basal Conditions and following Exposure to Cyclic Strain

Davenport, C., Harper, E., Rochfort, K. D., Forde, H. E., Smith, D., & Cummins, P. M. (2018) · Journal of Vascular Research · doi:10.1159/000486787 · Cited by 10

The role of 5‐lipoxygenase in Aggregatibacter actinomycetemcomitans‐induced alveolar bone loss

Madeira, M. F. M., Queiroz‐Junior, C. M., Corrêa, J. D., Werneck, S. M. C., Machado, F. S., Cunha, T. M., Garlet, G. P., Teixeira, M. M., Silva, T. A., & Souza, D. G. (2017) · Journal Of Clinical Periodontology · doi:10.1111/jcpe.12755 · Cited by 10

Osteoprotegerin in diabetic osteopathy

Valentini, A., Cianfarani, M. A., Federici, M., Tarantino, U., & Bertoli, A. (2019) · Nutrition Metabolism and Cardiovascular Diseases · doi:10.1016/j.numecd.2019.08.018 · Cited by 10

No relationship between osteoprotegerin concentrations and endothelial dysfunction in non-obese women with and without polycystic ovary syndrome

Abalı, R., Taşdemir, N., Alpsoy, Ş., Tasdemir, U. G., Güzel, S., Yüksel, M. A., Yüksel, İ. T., & Yılmaz, M. (2014) · Archives of Gynecology and Obstetrics · doi:10.1007/s00404-014-3499-7 · Cited by 10

Circulating osteoprotegerin and asymptomatic carotid atherosclerosis in postmenopausal non diabetic women

Albu, A., Bondor, C. I., Craciun, A. M., & Fodor, D. (2014) · Advances in Medical Sciences · doi:10.1016/j.advms.2014.08.002 · Cited by 9

LPS-induced inflammation disorders bone modeling and remodeling by inhibiting angiogenesis and disordering osteogenesis in chickens

Tong, X., Zhang, J., & Li, J. (2020) · Inflammation Research · doi:10.1007/s00011-020-01361-x · Cited by 10

Assessment of the Healing of Dental Implant Surgical Site Following Low-Level Laser Therapy Using Bioclinical Parameters: An Exploratory Study

Palled, V., Rao, J., Singh, R. D., Tripathi, S., Singh, K., Radav, R., Verma, U. P., & Chand, P. (2020) · Journal of Oral Implantology · doi:10.1563/aaid-joi-d-18-00316 · Cited by 9

Regulation of bone lysis in inflammatory diseases

Haynes, D. R., & Crotti, T. N. (2003) · Inflammopharmacology · doi:10.1163/156856003322699500 · Cited by 9

Biologie du remodelage osseux

Couret, I. (2004) · Médecine Nucléaire · Cited by 9

Correlation of increased plasma osteoprotegerin and cardiovascular risk factors in patients with adult growth hormone deficiency.

Xia, J., Li, L., Ren, W., Zheng, X., Liu, C., Li, J., Chen, T., Li, X., Wang, L., & Hu, Y. (2015) · Europe PMC (PubMed Central) · Cited by 8

Plasma levels of sRANKL and OPG are associated with atherogenic cytokines in patients with intermediate cardiovascular risk

Raaz‐Schrauder, D., Schrauder, M. G., Stumpf, C., Lewczuk, P., Kilian, T., Dietel, B., Garlichs, C. D., Schlundt, C., Achenbach, S. S., & Klinghammer, L. (2017) · Heart and Vessels · doi:10.1007/s00380-017-0998-z · Cited by 8

Reproductive and Lifestyle Factors and Circulating sRANKL and OPG Concentrations in Women: Results from the EPIC Cohort

Sarink, D., Yang, J., Johnson, T., Chang-Claude, J. C., Overvad, K., Olsen, A., Tjønneland, A. M., Fournier, A., Mancini, F. R., Kvaskoff, M., et al. (2019) · Cancer Epidemiology Biomarkers & Prevention · doi:10.1158/1055-9965.epi-19-0241 · Cited by 8

The Impact of Hyperbaric Oxygen Therapy on Serum C-Reactive Protein Levels, Osteoprotegerin Expression, and Osteoclast Numbers in Induced-Periodontitis Diabetic Rats

Mulawarmanti, D., Parisihni, K., & Widyastuti, W. (2020) · European Journal of Dentistry · doi:10.1055/s-0040-1712072 · Cited by 8

Osteoprotegerin: regulator, protector and marker

Othmane, T., Speer, G., Fekete, B., Szabó, T., Egresits, J., Fodor, E., Kiss, I., Nemcsik, J., Szabó, A., Németh, Z., et al. (2008) · Orvosi Hetilap · doi:10.1556/oh.2008.28470 · Cited by 7

Elevated plasma osteoprotegerin levels are associated with venous thrombosis and bleeding in patients with polycythemia vera

Kees, M., Wiesbauer, F., Gisslinger, B., Wagner, R., Shehata, M. M., & Gisslinger, H. (2004) · Thrombosis and Haemostasis · doi:10.1160/th04-06-0394 · Cited by 7

Characterization of synovial cell clones isolated from rheumatoid arthritis patients: Possible involvement of TNF-α in reduction of osteoprotegerin in synovium

Zhao, B., Takami, M., Miyamoto, Y., Suzawa, T., Yamada, A., Mochizuki, A., Yasuhara, R., Wang, X., Inoue, T., Namiki, O., et al. (2007) · Cytokine · doi:10.1016/j.cyto.2007.10.013 · Cited by 7

Low Carotid Calcium Score Is Associated With Higher Levels of Glycosaminoglycans, Tumor Necrosis Factor-Alpha, and Parathyroid Hormone in Human Carotid Plaques

Edsfeldt, A., Dias, N. V., Elmståhl, B., Müller, M. F., Berg, K. E., Nitulescu, M., Persson, A. F., Ekberg, O., & Gonçalves, I. (2011) · Stroke · doi:10.1161/strokeaha.111.620658 · Cited by 7

Coordination of early cellular reactions during activation of bone resorption in the rat mandible periosteum: An immunohistochemical study

Hassan, B., Fouilloux, I., Baroukh, B., Llorens, A., Duplan, M. B., Gosset, M., Cherruau, M., & Jl, S. (2017) · Heliyon · doi:10.1016/j.heliyon.2017.e00430 · Cited by 7

Estradiol Enhances Osteolytic Lesions in Mice Inoculated with Human Estrogen Receptor-Negative MDA-231 Breast Cancer Cells in vivo

Winding, B., Misander, H., Høegh-Andersen, P., Brünner, N., & Foged, N. T. (2003) · Breast Cancer Research and Treatment · doi:10.1023/a:1022943127689 · Cited by 7

The Role of the Receptor Activator of Nuclear Factor Kappa-B Ligand/Osteoprotegerin Ratio in Vascular Diseases: A Therapeutic Approach

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Osteoprotegerin Is Essential for the Development of Endothelial Dysfunction Induced by Angiotensin II in Mice

Dutka, M., Garczorz, W., Kosowska, A., Buczek, E., Godek, P., Wojakowski, W., & Francuz, T. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25126434 · Cited by 6

Interleukin-4 and Interleukin-13 Stimulate the Osteoclast Inhibitor Osteoprotegerin by Human Endothelial Cells Through the STAT6 Pathway

Stein, N., Kreutzmann, C., Zimmermann, S.-P., Niebergall, U., Hellmeyer, L., Goettsch, C., Schoppet, M., & Hofbauer, L. C. (2008) · Journal of Bone and Mineral Research · doi:10.1359/jbmr.080203 · Cited by 81

Role of receptor activator of nuclear factor-κB ligand and osteoprotegerin in bone cell biology

Hofbauer, L. C., & Heufelder, A. E. (2001) · Journal of Molecular Medicine · doi:10.1007/s001090100226 · Cited by 586

Human Microvascular Endothelial Cell Activation by IL-1 and TNF-α Stimulates the Adhesion and Transendothelial Migration of Circulating Human CD14+ Monocytes That Develop With RANKL Into Functional Osteoclasts

Kindle, L., Rothe, L., Kriss, M. S., Osdoby, P., & Collin‐Osdoby, P. (2006) · Journal of Bone and Mineral Research · doi:10.1359/jbmr.051027 · Cited by 117

The Effect of Paricalcitol on Osteoprotegerin Production by Human Peripheral Blood Mononuclear Cells

Eleftheriadis, T., Antoniadi, G., Liakopoulos, V., & Galaktidou, G. (2009) · The Journal of Rheumatology · doi:10.3899/jrheum.080987 · Cited by 6

VEGF-C, a Lymphatic Growth Factor, Is a RANKL Target Gene in Osteoclasts That Enhances Osteoclastic Bone Resorption through an Autocrine Mechanism

Zhang, Q., Guo, R., Lu, Y., Zhao, L., Zhou, Q., Schwarz, E. M., Huang, J. L., Chen, D., Jin, Z., Boyce, B. F., et al. (2008) · Journal of Biological Chemistry · doi:10.1074/jbc.m708055200 · Cited by 89